Evidence for a synergistic action of glutaric and 3-hydroxyglutaric acids disturbing rat brain energy metabolism

International Journal of Developmental Neuroscience

Volumn 25, Issue 6, 2007, Pages 391-398

  Ferreira, Gustavo C ^a   Tonin, Anelise ^a   Schuck, Patrícia F ^a   Viegas, Carolina M ^a   Ceolato, Paula C ^a   Latini, Alexandra ^b   Perry, Marcos L S ^a   Wyse, Angela T S ^a   Dutra Filho, Carlos S ^a   Wannmacher, Clóvis M D ^a   Vargas, Carmen R ^a,c   Wajner, Moacir ^a,c,d  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^c HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^d UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

Author keywords

3 Hydroxyglutaric acid; Energy metabolism; Glutaric acid; Glutaric acidemia type I; Quinolinic acid

Indexed keywords

3 HYDROXYGLUTARIC ACID; ACETIC ACID; CARBON DIOXIDE; CATALASE; CREATINE KINASE; GLUCOSE; GLUTARIC ACID; GLUTARYL COENZYME A DEHYDROGENASE; GLUTATHIONE; PYRUVATE DEHYDROGENASE; QUINOLINIC ACID; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN METABOLISM; BRAIN TISSUE; CONTROLLED STUDY; DRUG POTENTIATION; ENERGY METABOLISM; ENZYME DEFICIENCY; GLUCOSE UTILIZATION; GLUTARIC ACIDEMIA TYPE 1; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIOXIDANTS; BRAIN; BRAIN CHEMISTRY; BRAIN DISEASES, METABOLIC; CREATINE KINASE; DRUG SYNERGISM; ENERGY METABOLISM; GLUCOSE; GLUTARATES; LACTIC ACID; MULTIPLE ACYL COENZYME A DEHYDROGENASE DEFICIENCY; ORGAN CULTURE TECHNIQUES; OXIDATIVE STRESS; PYRUVATE DEHYDROGENASE COMPLEX; QUINOLINIC ACID; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES;

RATTUS;

EID: 35748951029     PISSN: 07365748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2007.05.009     Document Type: Article

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