-
1
-
-
84871695502
-
dSir2 in the adult fat body, but not in muscles, regulates life span in a diet-dependent manner
-
Banerjee, K.K., Ayyub, C., Ali, S.Z., Mandot, V., Prasad, N., Kolthur-Seetharam, N.G.U., dSir2 in the adult fat body, but not in muscles, regulates life span in a diet-dependent manner. Cell Rep. 2 (2012), 1485–1491.
-
(2012)
Cell Rep.
, vol.2
, pp. 1485-1491
-
-
Banerjee, K.K.1
Ayyub, C.2
Ali, S.Z.3
Mandot, V.4
Prasad, N.5
Kolthur-Seetharam, N.G.U.6
-
2
-
-
84897460111
-
HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy
-
Beharry, A.W., Sandesara, P.B., Roberts, B.M., Ferreira, L.F., Senf, S.M., Judge, A.R., HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy. J. Cell Sci. 127 (2014), 1441–1453.
-
(2014)
J. Cell Sci.
, vol.127
, pp. 1441-1453
-
-
Beharry, A.W.1
Sandesara, P.B.2
Roberts, B.M.3
Ferreira, L.F.4
Senf, S.M.5
Judge, A.R.6
-
3
-
-
0034610367
-
Genomewide studies of histone deacetylase function in yeast
-
Bernstein, B.E., Tong, J.K., Schreiber, S.L., Genomewide studies of histone deacetylase function in yeast. Proc. Natl. Acad. Sci. U. S. A. 97 (2000), 13708–13713.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 13708-13713
-
-
Bernstein, B.E.1
Tong, J.K.2
Schreiber, S.L.3
-
4
-
-
80053168829
-
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
-
Burnett, C., Valentini, S., Cabreiro, F., Goss, M., Somogyvári, M., Piper, M.D., Hoddinott, M., Sutphin, G.L., Leko, V., McElwee, J.J., Vazquez-Manrique, R.P., Orfila, A.M., Ackerman, D., Au, C., Vinti, G., Riesen, M., Howard, K., Neri, C., Bedalov, A., Kaeberlein, M., Soti, C., Partridge, L., Gems, D., Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature 477 (2011), 482–485.
-
(2011)
Nature
, vol.477
, pp. 482-485
-
-
Burnett, C.1
Valentini, S.2
Cabreiro, F.3
Goss, M.4
Somogyvári, M.5
Piper, M.D.6
Hoddinott, M.7
Sutphin, G.L.8
Leko, V.9
McElwee, J.J.10
Vazquez-Manrique, R.P.11
Orfila, A.M.12
Ackerman, D.13
Au, C.14
Vinti, G.15
Riesen, M.16
Howard, K.17
Neri, C.18
Bedalov, A.19
Kaeberlein, M.20
Soti, C.21
Partridge, L.22
Gems, D.23
more..
-
5
-
-
79952775153
-
Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppresing authophagy
-
Cao, D.J., Wang, Z.V., Battiprolu, P.K., Jiang, N., Morales, C.R., Kong, Y., Rothermel, B.A., Gillete, T.G., Hill, J.A., Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppresing authophagy. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 4123–4128.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 4123-4128
-
-
Cao, D.J.1
Wang, Z.V.2
Battiprolu, P.K.3
Jiang, N.4
Morales, C.R.5
Kong, Y.6
Rothermel, B.A.7
Gillete, T.G.8
Hill, J.A.9
-
6
-
-
28844469898
-
Increase in activity during calroie restriction require Sirt1
-
Chen, D., Steele, A.D., Lindquist, S., Guarente, L., Increase in activity during calroie restriction require Sirt1. Science, 310, 2005, 1641.
-
(2005)
Science
, vol.310
, pp. 1641
-
-
Chen, D.1
Steele, A.D.2
Lindquist, S.3
Guarente, L.4
-
7
-
-
68949212379
-
Lysine cetylation targets protein comolexes and co-regulates major cellulsr functions
-
Choudhary, C., Kumar, C., Gnad, F., Nielse, M.L., Rehmen, M., Walther, T.C., Olsen, J.V., Mann, M., Lysine cetylation targets protein comolexes and co-regulates major cellulsr functions. Science 325 (2009), 834–840.
-
(2009)
Science
, vol.325
, pp. 834-840
-
-
Choudhary, C.1
Kumar, C.2
Gnad, F.3
Nielse, M.L.4
Rehmen, M.5
Walther, T.C.6
Olsen, J.V.7
Mann, M.8
-
8
-
-
0029805633
-
The histone deacetylase RPD3 counteracts genomic silencing in Drosophila and yeast
-
De Rubertis, F., Kadosh, D., Henchoz, S., Pauli, D., Reuter, G., Struhl, K., Spierer, P., The histone deacetylase RPD3 counteracts genomic silencing in Drosophila and yeast. Nature 384 (1996), 589–591.
-
(1996)
Nature
, vol.384
, pp. 589-591
-
-
De Rubertis, F.1
Kadosh, D.2
Henchoz, S.3
Pauli, D.4
Reuter, G.5
Struhl, K.6
Spierer, P.7
-
9
-
-
13844309711
-
Clinical development of histone deacetylase inhibitors as anticancer agents
-
Drummond, D.C., Noble, C.O., Kirpotin, D.B., Guo, Z., Scott, G.K., Benz, C.C., Clinical development of histone deacetylase inhibitors as anticancer agents. Annu. Rev. Pharmacol. Toxicol. 45 (2005), 495–528.
-
(2005)
Annu. Rev. Pharmacol. Toxicol.
, vol.45
, pp. 495-528
-
-
Drummond, D.C.1
Noble, C.O.2
Kirpotin, D.B.3
Guo, Z.4
Scott, G.K.5
Benz, C.C.6
-
10
-
-
79952529158
-
A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism
-
Feng, D., Liu, T., Sun, Z., Bugge, A., Mullican, S.E., Alenghat, T., Liu, X.S., Lazar, M.A., A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism. Science 331 (2011), 1315–1319.
-
(2011)
Science
, vol.331
, pp. 1315-1319
-
-
Feng, D.1
Liu, T.2
Sun, Z.3
Bugge, A.4
Mullican, S.E.5
Alenghat, T.6
Liu, X.S.7
Lazar, M.A.8
-
11
-
-
34248523169
-
Recovery of learning and memory is associated with chromatin remodelling
-
Fischer, A., Sananbenesi, F., Wang, X., Dobbin, M., Tsai, L.H., Recovery of learning and memory is associated with chromatin remodelling. Nature 447 (2007), 178–182.
-
(2007)
Nature
, vol.447
, pp. 178-182
-
-
Fischer, A.1
Sananbenesi, F.2
Wang, X.3
Dobbin, M.4
Tsai, L.H.5
-
12
-
-
52049126629
-
Histone deacetylase inhibitors improve learning consolidation in young and in KA-induced-neurodegeneration and SAMP-8-mutant mice
-
Fontan-Lozano, A., Romero-Granados, R., Troncoso, J., Munera, A., Delgado-Garcia, J.M., Carrion, A.M., Histone deacetylase inhibitors improve learning consolidation in young and in KA-induced-neurodegeneration and SAMP-8-mutant mice. Mol. Cell. Neurosci. 39 (2008), 193–201.
-
(2008)
Mol. Cell. Neurosci.
, vol.39
, pp. 193-201
-
-
Fontan-Lozano, A.1
Romero-Granados, R.2
Troncoso, J.3
Munera, A.4
Delgado-Garcia, J.M.5
Carrion, A.M.6
-
13
-
-
79954631819
-
dSir2 and longevity in Drosophila
-
Frankel, S., Ziafazeli, T., Rogina, B., dSir2 and longevity in Drosophila. Exp. Gerontol. 46 (2011), 391–396.
-
(2011)
Exp. Gerontol.
, vol.46
, pp. 391-396
-
-
Frankel, S.1
Ziafazeli, T.2
Rogina, B.3
-
14
-
-
84958149071
-
RPD3 histone deacetylase and nutrition have distinct but interacting effects on Drosophila longevity
-
Frankel, S., Woods, J.K., Ziafazeli, T., Rogina, B., RPD3 histone deacetylase and nutrition have distinct but interacting effects on Drosophila longevity. Aging 7 (2015), 1–18.
-
(2015)
Aging
, vol.7
, pp. 1-18
-
-
Frankel, S.1
Woods, J.K.2
Ziafazeli, T.3
Rogina, B.4
-
15
-
-
85001852252
-
Histone deacetylase (HDAC) inhibitors — emerging roles in neuronal memory, learning, synaptic plasticity and neural regeneration
-
Ganai, S.A., Ramadoss, M., Mahadevan, V., Histone deacetylase (HDAC) inhibitors — emerging roles in neuronal memory, learning, synaptic plasticity and neural regeneration. Curr. Neuropharmacol., 5, 2015, 15067.
-
(2015)
Curr. Neuropharmacol.
, vol.5
, pp. 15067
-
-
Ganai, S.A.1
Ramadoss, M.2
Mahadevan, V.3
-
16
-
-
66449123586
-
Acetylation/deacetylation modulates the stability of DNA replication licensing factor Cdt1
-
Glozak, M.A., Seto, E., Acetylation/deacetylation modulates the stability of DNA replication licensing factor Cdt1. J. Biol. Chem. 284 (2009), 11446–11453.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 11446-11453
-
-
Glozak, M.A.1
Seto, E.2
-
17
-
-
84941425076
-
Loss of histone deacetylase Hdac1 disrupts metabolic processes in intestinal epithelial cells
-
Gonneaud, A., Turgeon, N., Boisvert, F.M., Boudreau, F., Asselin, C., Loss of histone deacetylase Hdac1 disrupts metabolic processes in intestinal epithelial cells. FEBS Lett. 589 (2015), 2776–2783.
-
(2015)
FEBS Lett.
, vol.589
, pp. 2776-2783
-
-
Gonneaud, A.1
Turgeon, N.2
Boisvert, F.M.3
Boudreau, F.4
Asselin, C.5
-
18
-
-
47249153469
-
Sir2 mediates apoptosis through JNK-dependent pathways in Drosophila
-
Griswold, A.J., Chang, K.T., Runko, A.P., Knight, M.A., Min, K.T., Sir2 mediates apoptosis through JNK-dependent pathways in Drosophila. Proc. Natl. Acad. Sci. U. S. A. 105 (2008), 8673–8678.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 8673-8678
-
-
Griswold, A.J.1
Chang, K.T.2
Runko, A.P.3
Knight, M.A.4
Min, K.T.5
-
19
-
-
0033609055
-
Three proteins define a class of human histone deacetylases related to yeast Hda1p
-
Grozinger, C.M., Hassig, C.A., Schreiber, S.L., Three proteins define a class of human histone deacetylases related to yeast Hda1p. Proc. Natl. Acad. Sci. U. S. A. 96 (1999), 4868–4873.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 4868-4873
-
-
Grozinger, C.M.1
Hassig, C.A.2
Schreiber, S.L.3
-
20
-
-
0842325787
-
Histone deacetylase is a target of valproic acid-mediated cellular differentiation
-
Gurvich, N., Tsygankova, O.M., Meinkoth, J.L., Klein, P.S., Histone deacetylase is a target of valproic acid-mediated cellular differentiation. Cancer Res. 64 (2004), 1079–1086.
-
(2004)
Cancer Res.
, vol.64
, pp. 1079-1086
-
-
Gurvich, N.1
Tsygankova, O.M.2
Meinkoth, J.L.3
Klein, P.S.4
-
21
-
-
84886812954
-
The nextus of chromatin regulation and intermediary metabolism
-
Gut, P., Verdin, E., The nextus of chromatin regulation and intermediary metabolism. Nature 502 (2013), 489–498.
-
(2013)
Nature
, vol.502
, pp. 489-498
-
-
Gut, P.1
Verdin, E.2
-
22
-
-
77949887506
-
Mammalian sirtuins: biological insights and disease relevance
-
Haigis, M.C., Sinclair, D.A., Mammalian sirtuins: biological insights and disease relevance. Annu. Rev. Pathol. 5 (2010), 253–295.
-
(2010)
Annu. Rev. Pathol.
, vol.5
, pp. 253-295
-
-
Haigis, M.C.1
Sinclair, D.A.2
-
23
-
-
84877648303
-
Overexpression of Sir2 in the adult fat body is sufficient to extend lifespan of male and female drosophila
-
Hoffman, J., Romey, R., Fink, C., Yong, L., Roder, T., Overexpression of Sir2 in the adult fat body is sufficient to extend lifespan of male and female drosophila. Aging 4 (2013), 315–327.
-
(2013)
Aging
, vol.4
, pp. 315-327
-
-
Hoffman, J.1
Romey, R.2
Fink, C.3
Yong, L.4
Roder, T.5
-
24
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
Imai, S., Armstrong, C.M., Kaberlein, M., Guarente, L., Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403 (2000), 795–800.
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaberlein, M.3
Guarente, L.4
-
26
-
-
0037112901
-
MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation
-
Ito, A., Kawaguchi, Y., Lai, C.H., Kovacs, J.J., Higashimoto, Y., Appella, E., Yao, T.P., MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation. EMBO J. 21 (2002), 6236–6245.
-
(2002)
EMBO J.
, vol.21
, pp. 6236-6245
-
-
Ito, A.1
Kawaguchi, Y.2
Lai, C.H.3
Kovacs, J.J.4
Higashimoto, Y.5
Appella, E.6
Yao, T.P.7
-
27
-
-
0036696982
-
Distinct roles of processes modulated by histone deacetylases Rpd3p, Hda1p, and Sir2p in life extension by caloric restriction in yeast
-
Jiang, J.C., Wawryn, J., Shantha Kumara, H.M., Jazwinski, S.M., Distinct roles of processes modulated by histone deacetylases Rpd3p, Hda1p, and Sir2p in life extension by caloric restriction in yeast. Exp. Gerontol. 37 (2002), 1023–1030.
-
(2002)
Exp. Gerontol.
, vol.37
, pp. 1023-1030
-
-
Jiang, J.C.1
Wawryn, J.2
Shantha Kumara, H.M.3
Jazwinski, S.M.4
-
28
-
-
0034617261
-
Histone deacetylases specifically down-regulate p53-dependent gene activation
-
Juan, L.J., Shia, W.J., Chen, M.H., Yang, W.M., Seto, E., Lin, Y.S., Wu, C.W., Histone deacetylases specifically down-regulate p53-dependent gene activation. J. Biol. Chem. 275 (2000), 20436–20443.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 20436-20443
-
-
Juan, L.J.1
Shia, W.J.2
Chen, M.H.3
Yang, W.M.4
Seto, E.5
Lin, Y.S.6
Wu, C.W.7
-
29
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
Kaeberlein, M., McVey, M., Guerente, L., The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 13 (1999), 2570–2580.
-
(1999)
Genes Dev.
, vol.13
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guerente, L.3
-
30
-
-
84858000209
-
The sirtuin SIRT6 regulates lifespan in male mice
-
Kanfi, Y., Naiman, S., Amir, G., Peshti, V., Zinman, G., Nahum, L., Bar-Joseph, Z., Cohen, H.Y., The sirtuin SIRT6 regulates lifespan in male mice. Nature 483 (2012), 218–221.
-
(2012)
Nature
, vol.483
, pp. 218-221
-
-
Kanfi, Y.1
Naiman, S.2
Amir, G.3
Peshti, V.4
Zinman, G.5
Nahum, L.6
Bar-Joseph, Z.7
Cohen, H.Y.8
-
31
-
-
0037154205
-
Life span extension in drosophila by feeding a drug
-
Kang, H., Benzer, S., Min, K., Life span extension in drosophila by feeding a drug. Proc. Natl. Acad. Sci. U. S. A. 99 (2002), 838–843.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 838-843
-
-
Kang, H.1
Benzer, S.2
Min, K.3
-
32
-
-
0030877160
-
A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulators
-
Kasten, M.M., Dorland, S., Stillman, D.J., A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulators. Mol. Cell. Biol. 17 (1997), 4852–4858.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 4852-4858
-
-
Kasten, M.M.1
Dorland, S.2
Stillman, D.J.3
-
33
-
-
79954632599
-
Role of TOR signaling in aging and related biological processes in Drosophila melanogaster
-
Katewa, S.D., Kapahi, P., Role of TOR signaling in aging and related biological processes in Drosophila melanogaster. Exp. Gerontol. 46 (2011), 382–390.
-
(2011)
Exp. Gerontol.
, vol.46
, pp. 382-390
-
-
Katewa, S.D.1
Kapahi, P.2
-
34
-
-
53249130741
-
Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
-
Kazantsev, A.G., Thompson, L.M., Therapeutic application of histone deacetylase inhibitors for central nervous system disorders. Nat. Rev. Drug Discov. 7 (2008), 854–868.
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, pp. 854-868
-
-
Kazantsev, A.G.1
Thompson, L.M.2
-
35
-
-
0032831936
-
Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae
-
Kim, S., Benguria, A., Lai, C.Y., Jazwinski, S.M., Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae. Mol. Biol. Cell 10 (1999), 3125–3136.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 3125-3136
-
-
Kim, S.1
Benguria, A.2
Lai, C.Y.3
Jazwinski, S.M.4
-
36
-
-
41949120723
-
Liver-specific deletion of histone deacetylase 3 discrupts metabolic transcriptional network
-
Knutson, S.K., Chyla, B.J., Amann, J.M., Bhaskara, S., Huppert, S.S., Hiebert, S.W., Liver-specific deletion of histone deacetylase 3 discrupts metabolic transcriptional network. EMBO J. 27 (2008), 1017–1028.
-
(2008)
EMBO J.
, vol.27
, pp. 1017-1028
-
-
Knutson, S.K.1
Chyla, B.J.2
Amann, J.M.3
Bhaskara, S.4
Huppert, S.S.5
Hiebert, S.W.6
-
37
-
-
84943400659
-
Heart-specific Rpd3 downregulation enhances cardiac function and longevity
-
Kopp, Z.A., et al. Heart-specific Rpd3 downregulation enhances cardiac function and longevity. Aging 7 (2015), 648–663.
-
(2015)
Aging
, vol.7
, pp. 648-663
-
-
Kopp, Z.A.1
-
38
-
-
34047255367
-
Valproic acid, a molecular lead to multiple regulatory pathways
-
Kostrouchova, M., Kostrouch, Z., Kostrouchova, M., Valproic acid, a molecular lead to multiple regulatory pathways. Folia Biol. 53 (2007), 37–49.
-
(2007)
Folia Biol.
, vol.53
, pp. 37-49
-
-
Kostrouchova, M.1
Kostrouch, Z.2
Kostrouchova, M.3
-
39
-
-
0032582489
-
Extended life-span and stress resistance in the Drosophila mutant methuselah
-
Lin, Y.J., Seroude, L., Benzer, S., Extended life-span and stress resistance in the Drosophila mutant methuselah. Science 282 (1998), 943–946.
-
(1998)
Science
, vol.282
, pp. 943-946
-
-
Lin, Y.J.1
Seroude, L.2
Benzer, S.3
-
40
-
-
80052939858
-
Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction
-
Lu, J.-Y., Lin, Y.-Y., Sheu, J.-C., Wu, J.-T., Lee, F.-J., Chen, Y., Lin, M.-I., Chiang, F.-T., Tai, T.-Y., Berger, S.L., Zhao, Y., Tsai, K.-S., Zhu, H., Chuang, L.-M., Boeke, J.D., Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction. Cell 146 (2011), 1–11.
-
(2011)
Cell
, vol.146
, pp. 1-11
-
-
Lu, J.-Y.1
Lin, Y.-Y.2
Sheu, J.-C.3
Wu, J.-T.4
Lee, F.-J.5
Chen, Y.6
Lin, M.-I.7
Chiang, F.-T.8
Tai, T.-Y.9
Berger, S.L.10
Zhao, Y.11
Tsai, K.-S.12
Zhu, H.13
Chuang, L.-M.14
Boeke, J.D.15
-
41
-
-
0033535957
-
The Rpd3 histone deacetylase is required for segmentation of the Drosophila embryo
-
Mannervik, M., Levine, M., The Rpd3 histone deacetylase is required for segmentation of the Drosophila embryo. Proc. Natl. Acad. Sci. U. S. A. 96 (1999), 6797–6801.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 6797-6801
-
-
Mannervik, M.1
Levine, M.2
-
42
-
-
33846122993
-
Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug
-
Marks, P.A., Breslow, R., Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug. Nat. Biotechnol. 25 (2007), 84–90.
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 84-90
-
-
Marks, P.A.1
Breslow, R.2
-
43
-
-
84872761579
-
Chemical regulation of mid- and late-life longevities in Drosophila
-
McDonald, P., Maizi, B.M., Arking, R., Chemical regulation of mid- and late-life longevities in Drosophila. Exp. Gerontol. 48 (2013), 240–249.
-
(2013)
Exp. Gerontol.
, vol.48
, pp. 240-249
-
-
McDonald, P.1
Maizi, B.M.2
Arking, R.3
-
44
-
-
84871650811
-
Metabolic reprogramming by class i and II histone deacetylases
-
Mihaylova, M.M., Shaw, R.J., Metabolic reprogramming by class i and II histone deacetylases. Trends Endocrinol. Metab. 24 (2012), 48–57.
-
(2012)
Trends Endocrinol. Metab.
, vol.24
, pp. 48-57
-
-
Mihaylova, M.M.1
Shaw, R.J.2
-
45
-
-
66049101024
-
Histone deacetylase 1 and 2 control the progression of neural precursors to neurons during brain development
-
Montgomery, R.L., Hsieh, J., Barbosa, A.C., Richardson, J.A., Olson, E.N., Histone deacetylase 1 and 2 control the progression of neural precursors to neurons during brain development. Proc. Natl. Acad. Sci. U. S. A. 106 (2009), 7876–7881.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 7876-7881
-
-
Montgomery, R.L.1
Hsieh, J.2
Barbosa, A.C.3
Richardson, J.A.4
Olson, E.N.5
-
46
-
-
0033952282
-
Mutational analysis of a histone deacetylase in Drosophila melanogaster: missense mutations suppress gene silencing associated with position effect variegation
-
Mottus, R., Sobel, R.E., Grigliatti, T.A., Mutational analysis of a histone deacetylase in Drosophila melanogaster: missense mutations suppress gene silencing associated with position effect variegation. Genetics 154 (2000), 657–668.
-
(2000)
Genetics
, vol.154
, pp. 657-668
-
-
Mottus, R.1
Sobel, R.E.2
Grigliatti, T.A.3
-
47
-
-
53249114029
-
Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease
-
Pallos, J., Bodai, L., Lukacsovich, T., Purcell, J.M., Steffan, J.S., Thompson, L.M., Marsh, J.L., Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease. Hum. Mol. Genet. 17 (2008), 3767–3775.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 3767-3775
-
-
Pallos, J.1
Bodai, L.2
Lukacsovich, T.3
Purcell, J.M.4
Steffan, J.S.5
Thompson, L.M.6
Marsh, J.L.7
-
48
-
-
77953589623
-
dSir2 mediates the increased spontaneous physical activity in flies on calorie restriction
-
Parashar, V., Rogina, B., dSir2 mediates the increased spontaneous physical activity in flies on calorie restriction. Aging 1 (2009), 529–541.
-
(2009)
Aging
, vol.1
, pp. 529-541
-
-
Parashar, V.1
Rogina, B.2
-
49
-
-
0034669165
-
Chromosomal localization links the SIN3–RPD3 complex to the regulation of chromatin condensation, histone acetylation and gene expression
-
Pile, L.A., Wassarman, D.A., Chromosomal localization links the SIN3–RPD3 complex to the regulation of chromatin condensation, histone acetylation and gene expression. EMBO J. 19 (2000), 6131–6140.
-
(2000)
EMBO J.
, vol.19
, pp. 6131-6140
-
-
Pile, L.A.1
Wassarman, D.A.2
-
50
-
-
0141621080
-
The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: implications for the regulation of energy metabolism
-
Pile, L.A., Spellman, P.T., Katzenberger, R.J., Wassarman, D.A., The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: implications for the regulation of energy metabolism. J. Biol. Chem. 278 (2003), 37840–37848.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 37840-37848
-
-
Pile, L.A.1
Spellman, P.T.2
Katzenberger, R.J.3
Wassarman, D.A.4
-
51
-
-
84900481019
-
Increased mitochondrial biogenesis preserves intestinal stem cell homeostasis and contributes to longevity in Indy mutant flies
-
Rogers, R.P., Rogina, B., Increased mitochondrial biogenesis preserves intestinal stem cell homeostasis and contributes to longevity in Indy mutant flies. Aging 6 (2014), 335–350.
-
(2014)
Aging
, vol.6
, pp. 335-350
-
-
Rogers, R.P.1
Rogina, B.2
-
52
-
-
8644224064
-
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
-
Rogina, B., Helfand, S.L., Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc. Natl. Acad. Sci. U. S. A. 101 (2004), 15998–16003.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 15998-16003
-
-
Rogina, B.1
Helfand, S.L.2
-
53
-
-
18744416824
-
Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction
-
Rogina, B., Helfand, S.L., Frankel, S., Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction. Science, 298, 2002, 1745.
-
(2002)
Science
, vol.298
, pp. 1745
-
-
Rogina, B.1
Helfand, S.L.2
Frankel, S.3
-
54
-
-
84921425001
-
Erasers of histone acetylations: the histone deacetyase enzymes
-
Seto, E., Yoshida, M., Erasers of histone acetylations: the histone deacetyase enzymes. Cold Spring Harb. Perspect. Biol., 6, 2014, a08713.
-
(2014)
Cold Spring Harb. Perspect. Biol.
, vol.6
, pp. a08713
-
-
Seto, E.1
Yoshida, M.2
-
55
-
-
0029932598
-
A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p
-
Taunton, J., Hassig, C.A., Schreiber, S.L., A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science 272 (1996), 408–411.
-
(1996)
Science
, vol.272
, pp. 408-411
-
-
Taunton, J.1
Hassig, C.A.2
Schreiber, S.L.3
-
56
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum, H.A., Guarente, L., Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410 (2001), 227–230.
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
57
-
-
0026060619
-
RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae
-
Vidal, M., Gaber, R.F., RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae. Mol. Cell. Biol. 11 (1991), 6317–6327.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 6317-6327
-
-
Vidal, M.1
Gaber, R.F.2
-
58
-
-
0026046959
-
RPD1 (SIN3/UME4) is required for maximal activation and repression of diverse yeast genes
-
Vidal, M., Strich, R., Esposito, R.E., Gaber, R.F., RPD1 (SIN3/UME4) is required for maximal activation and repression of diverse yeast genes. Mol. Cell. Biol. 11 (1991), 6306–6316.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 6306-6316
-
-
Vidal, M.1
Strich, R.2
Esposito, R.E.3
Gaber, R.F.4
-
59
-
-
84886768309
-
Increased expression of Drosophila Sir2 extends life span in a dose-dependent manner
-
Whitaker, R., Faulkner, S., Miyokawa, R., Burhenn, L., Henriksen, M., Wood, J.G., Helfand, S.L., Increased expression of Drosophila Sir2 extends life span in a dose-dependent manner. Aging 9 (2013), 682–691.
-
(2013)
Aging
, vol.9
, pp. 682-691
-
-
Whitaker, R.1
Faulkner, S.2
Miyokawa, R.3
Burhenn, L.4
Henriksen, M.5
Wood, J.G.6
Helfand, S.L.7
-
60
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
Wood, J.G., Rogina, B., Lavu, S., Howitz, K., Helfand, S.L., Tatar, M., Sinclair, D.A., Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 430 (2004), 686–689.
-
(2004)
Nature
, vol.430
, pp. 686-689
-
-
Wood, J.G.1
Rogina, B.2
Lavu, S.3
Howitz, K.4
Helfand, S.L.5
Tatar, M.6
Sinclair, D.A.7
-
61
-
-
39749127166
-
The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men
-
Yang, X.J., Seto, E., The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men. Nat. Rev. Mol. Cell Biol. 9 (2008), 206–218.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 206-218
-
-
Yang, X.J.1
Seto, E.2
-
62
-
-
0029850458
-
Transcriptional repression by YYi is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3
-
Yang, W.M., Inouye, C., Zeng, Y., Bearss, D., Seto, E., Transcriptional repression by YYi is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3. Proc. Natl. Acad. Sci. U. S. A. 93 (1996), 12845–12850.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 12845-12850
-
-
Yang, W.M.1
Inouye, C.2
Zeng, Y.3
Bearss, D.4
Seto, E.5
-
63
-
-
12244251445
-
Stat3 dimerization regulated by reversible acetylation of a single lysine residue
-
Yuan, Z.L., Guan, Y.J., Chatterjee, D., Chin, Y.E., Stat3 dimerization regulated by reversible acetylation of a single lysine residue. Science 307 (2005), 269–273.
-
(2005)
Science
, vol.307
, pp. 269-273
-
-
Yuan, Z.L.1
Guan, Y.J.2
Chatterjee, D.3
Chin, Y.E.4
-
64
-
-
15044356553
-
Lifespan extension and elevated hsp gene expression in Drosophila caused by histone deacetylase inhibitors
-
Zhao, Y., Sun, H., Lu, J., Li, X., Chen, X., Tao, D., Huang, W., Huang, B., Lifespan extension and elevated hsp gene expression in Drosophila caused by histone deacetylase inhibitors. J. Exp. Biol. 208 (2005), 687–705.
-
(2005)
J. Exp. Biol.
, vol.208
, pp. 687-705
-
-
Zhao, Y.1
Sun, H.2
Lu, J.3
Li, X.4
Chen, X.5
Tao, D.6
Huang, W.7
Huang, B.8
-
65
-
-
84864290214
-
Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid
-
Zhao, L., Chen, C.N., Hajji, N., Oliver, E., Cotroneo, E., Wharton, J., Wang, D., Li, M., McKinsey, T.A., Stenmark, K.R., et al. Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid. Circulation 126 (2012), 455–467.
-
(2012)
Circulation
, vol.126
, pp. 455-467
-
-
Zhao, L.1
Chen, C.N.2
Hajji, N.3
Oliver, E.4
Cotroneo, E.5
Wharton, J.6
Wang, D.7
Li, M.8
McKinsey, T.A.9
Stenmark, K.R.10
|