RPD3 histone deacetylase and nutrition have distinct but interacting effects on Drosophila longevity

Aging

Volumn 7, Issue 12, 2015, Pages 1112-1129

  Frankel, Stewart ^a   Woods, Jared ^b   Ziafazeli, Tahereh ^b,c   Rogina, Blanka ^b  

^a UNIVERSITY OF HARTFORD   (United States)

^b UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^c MCMASTER UNIVERSITY   (Canada)

Author keywords

Aging; Dietary restriction; Drosophila; Longevity; Rpd3

Indexed keywords

DROSOPHILA PROTEIN; HISTONE DEACETYLASE 1; RPD3 PROTEIN, DROSOPHILA;

ANIMAL; ANIMAL FOOD; DROSOPHILA MELANOGASTER; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; LONGEVITY; MALE; METABOLISM; MUTATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMAL FEED; ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENE EXPRESSION REGULATION; GENOTYPE; HISTONE DEACETYLASE 1; LONGEVITY; MALE; MUTATION; SIGNAL TRANSDUCTION;

EID: 84958149071     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100856     Document Type: Article

References (47)

1. Kenyon CJ. The genetics of ageing. Nature. 2010; 464:504-512.
2. Katewa SD and Kapahi P. Role of Tor signaling in aging and related biologica processes in Drosophila melanogaster. Exp. Gerontol. 2011; 46:382-390.
3. Kapahi P, Zid BM, Harper T, Koslover D, Sapin V, and Benzer S. Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway. Curr. Biol. 2004; 14:885-890.
4. rd, Steffen KK, Westman EA, Hu D, Dang N, Kerr EO, Kirkland KT, Fields S, and Kennedy BK. Regulation of yeast replicative life by Tor and Sch9 in response to nutrients. Science. 2005; 310:1193-6.
5. Jia K, Chen D, and Riddle DL. The Tor pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development. 2004; 131:3897-906.
6. Lamming DW, Ye L, Katajisto P, Goncalves MD, Saitoh M, Stevens DM, Davis JG, Salmon AB, Richardson A, Ahima RS, Guertin DA, Sabatini DM, and Baur JA. Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity. Science. 2012: 335:1638-1643.
7. Haberland M, Montgomery RL, and Olson EN. The many roles of histone deacetylases in development and physiology: implication for disease and therapy. Nat. Rev. Genet. 2009; 10:32-42.
8. Rogina B, Helfand SL, and Frankel S. Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction. Science 2002; 298:1745.
9. Rogina B and Helfand SL. Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc. Natl. Acad. Sci. USA 2004; 101:15998-16003.
10. Mottus R, Sobel, RE, and Grigliatti TA. Mutational analysis of a histone deacetylase in Drosophila melanogaster: missense mutations suppress gene silencing associated with position effect variegation. Genetics. 2000; 154:657-668.
11. Frankel S, Ziafazeli T, and Rogina B. dSir2 and longevity in Drosophila. Exp. Gerontol. 2011; 46:391-6.
12. Whitaker R, Faulkner S, Miyokawa R, Burthenn L, Henriksen M, Wood JG, and Helfand SL. Increased expression of Drosophila Sir2 extends life span in a dose-dependent manner. Aging. 2013; 5:682-91.
13. Edwards C, Canfield J, Copes N, Rehan M, Lipps D, and Bradshaw PC, D-beta-hydroxybutyrate extends lifespan in C. elegans. Aging. 2014; 6:621-44.
14. Kang H-L, Benzer S, and Min K-T. Life extension in Drosophila by feeding a drug. Proc. Natl. Acad. Sci. USA 2002; 99: 838-843.
15. Zhao Y, Sun H, Lu J, Li X, Chen X, Tao D, Huang W, and Huang B. Lifespan extension and elevated hsp gene expression in Drosophila caused by histone deacetylase inhibitors. J. Exp. Biol. 2005; 208:697-705.
16. McDonald P, Maizi BM, and Arking R. Chemical regulation of mid-and late-life longevities in Drosophila. Exp. Gerontol. 2013; 48:240-9.
17. Kim S, Benguria A, Lai C-Y, and Jazwinski SM. Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae. Mol. Biol. Cell. 1999; 10:3125-56.
18. Jiang JC, Wawryn J, Shantha Kumara HMC, and Jazwinski SM. Distinct roles of processes modulated by histone deacetylases Rpd3, Hda1p, and Sip2 in life extension by caloric restriction in yeast. Exp. Gerontol. 2002; 37:1023-30.
19. McCay CM, Crowell MF, andMaynard LA. The effect of retarded growth upon the length of life span and upon the ultimate body size. J. Nutr. 1935; 10:63-79.
20. Weindruch RH and Walford RL. The Retardation of Aging and Disease by Dietary Restriction. 1988; Springfield, IL, C. C. Thomas.
21. Alic N and Partridge L. Death and dessert: nutrient signaling pathways and aging. Curr. Opin. Cell Biol. 2011; 23:738-743.
22. Mair W, Piper MDW, Partridge L. Calories do not explain extension of life span by dietary restriction in Drosophila. PLoS Biol. 2005; 3:e223.
23. Partridge L, Piper MDW, and Mair W. Dietary restriction in Drosophila. Mech Aging Dev 2005; 126: 938-950.
24. Tatar M. The plate half-full: Status of research on the mechanisms of dietary restriction in Drosophila melanogaster. Exp. Gerontol. 2011; 46:363-368.
25. Pallos J, Bodai L, Lukacsovich T, Purcell JM, Steffan JS, Thompson LM, and Marsh JL. Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease. Hum. Mol. Genet. 2008; 17:3767-3775.
26. Bross TG, Rogina B, and Helfand SL. Behavioral, physical, and demographic changes in Drosophila populations through dietary restriction. Aging Cell, 2005; 4:309-317.
27. Gershman B, Puig O, Hang L, Peitzch RM, Tatar M, and Garofalo RS. High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO. Physiol. Genomics. 2007; 29:24-34.
28. De Rubertis F, Kadosh D, Henchoz S, Pauli D, Reuter G, Struhl K, and Spierer P. The histone deacetylase RPD3 conteracts genomic silencing in Drosophila and yeast. Nature. 1996; 384:589-91.
29. Chapman T, and Partridge L. Female fitness in Drosophila melanogaster: an interaction between the effects of nutrition and of encounter rate with males. Proc. R. Soc. Lond. B Biol. Sci. 1996; 263:755-59.
30. Grandison RC, Wong R, Bass TM, Partridge L, and Piper MDW. Effect of a standardized dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster. PLoS ONE. 2009; 4:e4067.
31. Lasko P and Sonenberg N. Coordinated transcriptional and translational control in metabolic homeostasis in flies. Genes Dev. 2007; 21:235-237.
32. Zid BM, Rogers AN, Katewa SD, Vargas MA, Kolipinski MC, Lu TA, Benzer S, and Kapahi P. 4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila. Cell. 2009; 139:149-160.
33. Bauer J, Chang C, Bae G, Morris SNS, and Helfand SL. Dominant-negative Dmp53 extends life span through the dTOR pathway in D. melanogaster. Mech. Ageing Dev. 2010; 131:193-201.
34. Partridge L, Alic N, Bjedov I, Piper MDW. Aging in Drosophila. The role of the insulin/Igf and Tor signaling network. Exp. Gerontol. 2011; 46:376-381.
35. Lu J-Y, Lin Y-Y, Sheu J-C, Wu J-T, Lee F-J, Chen Y, Lin M-I, Chiang F-T, Tai T-Y, Berger SL, Zhao Y, Tsai K-S, Zhu H, Chuang LM, Boeke JD. Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction. Cell. 2011; 146:969-979.
36. Burger JMS, Hwangbo DS, Corby-Harris V, and Promislow DEL. The functional cost and benefits of dietary restriction in Drosophila. Aging Cell. 2007; 6:63-71.
37. Chippindale AK, Leroi AM, Kim SB, and Rose MR. Phenotypic plasticity and selection in Drosophila life-history evolution. I. Nutrition and cost of reproduction. J. Evol. Biol. 1993; 6:171-193.
38. Katewa, SD, Demontis F, Kolipinski M, Hubbard A, Gill MS, Perrimon, N, Meloc S, and Kapahi P. Intramyocellular fatty-acid metabolism plays a critical role in medicting responses to dietary restriction in Drosophila melanogaster. Cell Metab. 2012; 16:97-103.
39. Wang PY, Neretti N, Whitaker R, Hosier S, Chang C, Lu D, Rogina B. and Helfand SL. Long-lived Indy and calorie restriction interact to extend life span. Proc Natl Acad Sci USA. 2009; 106:9262-9267.
40. Teleman AA, Chen Y-W and Cohen SM. 4E-BP functions as a metabolic brake used under stress conditions but not during normal growth. Genes Dev. 2005; 19:1844-1848;
41. Tettweiler G, Miron M, Jenkins M, Sonenberg N, and Lasko PF. Starvation and oxidative stress resistance in Drosophila are mediated through the eIF4E-binding protein, d4E-BP. Genes Dev. 2005; 19:1840-1843.
42. Bai H, Post S, Kang P and Tatar M. Drosophila longevity assurance conferred by reduced insulin receptor substrate Chico partially requires d4eBP. PLOS One. 2015; e:0134415
43. Rogina B and Helfand SL. Indy mutations and Drosophila longevity. Front. Genet. 2013; 4:47 doi: 10.3389/gene.2013.00047.
44. Woods J, Kowalski S, and Rogina B. Determination of the spontaneous locomotor activity in Drosophila melanogaster. J Vis. Exp. 2014; 86: doi: 10.3791/51449.
45. Chomczynski P. and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 1987; 162:156-9.
46. Rogers RP. and Rogina B. Increased mitochondrial biogenesis preserves intestinal stem cell homeostasis and contributes to longevity in Indy mutant flies. Aging (Albany, NY) 2014; 6:335-350.
47. Kopp ZA, et al. Heart-specific Rpd3 downregulation enhances cardiac function and longevity. Aging (Albany, NY). 2015; 7:648-663.