AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes

Genes and Development

Volumn 30, Issue 5, 2016, Pages 535-552

  Young, Nathan P ^a   Kamireddy, Anwesh ^a   Van Nostrand, Jeanine L ^a   Eichner, Lillian J ^a   Shokhirev, Maxim Nikolaievich ^b   Dayn, Yelena ^c   Shaw, Reuben J ^a  

^a Salk institute for Biological Sciences   (United States)

^b Razavi Newman Integrative Genomics and Bioinformatics Core   (United States)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

AMPK; Embryonic stem cells; Endoderm; Germ layer specification; Lysosomes; Tfeb; Wnt

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN DERIVATIVE; PROTEIN TFEB; UNCLASSIFIED DRUG; WNT PROTEIN; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; TCFEB PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FATE; CELL LINEAGE; CONTROLLED STUDY; EMBRYONIC STEM CELL; GENE INACTIVATION; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; ENDODERM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE; MUTATION; PATHOLOGY; WNT SIGNALING PATHWAY;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELL LINEAGE; EMBRYONIC STEM CELLS; ENDODERM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LYSOSOMES; MICE; MUTATION; SIGNAL TRANSDUCTION; WNT SIGNALING PATHWAY;

EID: 84959487667     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.274142.115     Document Type: Article

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