메뉴 건너뛰기




Volumn 5, Issue 2, 2016, Pages

Trial Watch—Immunostimulation with cytokines in cancer therapy

(13)  Vacchelli, Erika a,b,c,d,e   Aranda, Fernando f   Bloy, Norma a,b,c,d,e   Buqué, Aitziber a,b,c,d,e   Cremer, Isabelle a,b,c,d   Eggermont, Alexander e   Fridman, Wolf Hervé a,b,c,d   Fucikova, Jitka g,h   Galon, Jérôme a,b,c,d   Spisek, Radek g,h   Zitvogel, Laurence a,e   Kroemer, Guido a,b,c,d,e,i,j   Galluzzi, Lorenzo a,b,c,d,e  

a INSERM   (France)

Author keywords

Anticancer vaccines; checkpoint blockers; GM CSF; IL 2; oncolytic virotherapy; Type I interferon

Indexed keywords


EID: 84959386440     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.1080/2162402X.2015.1115942     Document Type: Article
Times cited : (41)

References (158)
  • 1
    • 38849201080 scopus 로고    scopus 로고
    • SnapShot: Cytokines I
    • 18243106
    • C.M.Tato, D.J.Cua. SnapShot: Cytokines I. Cell 2008; 132:324.e1; PMID:18243106
    • (2008) Cell , vol.132 , pp. 324
    • Tato, C.M.1    Cua, D.J.2
  • 2
    • 38849201080 scopus 로고    scopus 로고
    • SnapShot: Cytokines II
    • 18267079
    • C.M.Tato, D.J.Cua. SnapShot: Cytokines II. Cell 2008; 132:500; PMID:18267079
    • (2008) Cell , vol.132 , pp. 500
    • Tato, C.M.1    Cua, D.J.2
  • 3
    • 38849201080 scopus 로고    scopus 로고
    • SnapShot: Cytokines III
    • 18329374
    • C.M.Tato, D.J.Cua. SnapShot: Cytokines III. Cell 2008; 132:900; PMID:18329374
    • (2008) Cell , vol.132 , pp. 900
    • Tato, C.M.1    Cua, D.J.2
  • 4
    • 40749104204 scopus 로고    scopus 로고
    • SnapShot: Cytokines IV
    • C.M.Tato, D.J.Cua. SnapShot: Cytokines IV. Cell 2008; 132:1062.e1-2; PMID:18358817
    • (2008) Cell , vol.132 , pp. 1-2
    • Tato, C.M.1    Cua, D.J.2
  • 7
    • 0037326059 scopus 로고    scopus 로고
    • 2. Cytokines and chemokines
    • 12592293
    • L.C.Borish, J.W.Steinke. 2. Cytokines and chemokines. J Allergy Clin Immunol 2003; 111:S460-75; PMID:12592293; http://dx.doi.org/10.1067/mai.2003.108
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 460-475
    • Borish, L.C.1    Steinke, J.W.2
  • 8
    • 31544469229 scopus 로고    scopus 로고
    • 3. Cytokines and chemokines
    • 16455343
    • J.W.Steinke, L.Borish. 3. Cytokines and chemokines. J Allergy Clin Immunol 2006; 117:S441-5; PMID:16455343; http://dx.doi.org/10.1016/j.jaci.2005.07.001
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 441-445
    • Steinke, J.W.1    Borish, L.2
  • 9
    • 84926353551 scopus 로고    scopus 로고
    • Stress-related and homeostatic cytokines regulate Vgamma9Vdelta2 T-cell surveillance of mevalonate metabolism
    • 25960933
    • G.Gruenbacher, O.Nussbaumer, H.Gander, B.Steiner, N.Leonhartsberger, M.Thurnher. Stress-related and homeostatic cytokines regulate Vgamma9Vdelta2 T-cell surveillance of mevalonate metabolism. Oncoimmunology 2014; 3:e953410; PMID:25960933; http://dx.doi.org/10.4161/21624011.2014.953410
    • (2014) Oncoimmunology , vol.3 , pp. 953410
    • Gruenbacher, G.1    Nussbaumer, O.2    Gander, H.3    Steiner, B.4    Leonhartsberger, N.5    Thurnher, M.6
  • 10
    • 85027950647 scopus 로고    scopus 로고
    • Cytokines: true to their family name
    • 23827957
    • M.Papatriantafyllou. Cytokines: true to their family name. Nat Rev Immunol 2013; 13:544-5; PMID:23827957; http://dx.doi.org/10.1038/nri3496
    • (2013) Nat Rev Immunol , vol.13 , pp. 544-545
    • Papatriantafyllou, M.1
  • 11
    • 84886944873 scopus 로고    scopus 로고
    • Targeting two co-operating cytokines efficiently shapes immune responses
    • 23802072
    • A.A.Hombach, H.Abken. Targeting two co-operating cytokines efficiently shapes immune responses. Oncoimmunology 2013; 2:e23205; PMID:23802072; http://dx.doi.org/10.4161/onci.23205
    • (2013) Oncoimmunology , vol.2 , pp. 23205
    • Hombach, A.A.1    Abken, H.2
  • 12
    • 84871684612 scopus 로고    scopus 로고
    • New insights into mechanisms of stem cell daughter fate determination in regenerative tissues
    • 23273858
    • A.Sada, T.Tumbar. New insights into mechanisms of stem cell daughter fate determination in regenerative tissues. Int Rev Cell Mol Biol 2013; 300:1-50; PMID:23273858; http://dx.doi.org/10.1016/B978-0-12-405210-9.00001-1
    • (2013) Int Rev Cell Mol Biol , vol.300 , pp. 1-50
    • Sada, A.1    Tumbar, T.2
  • 13
    • 77952921841 scopus 로고    scopus 로고
    • The colony-stimulating factors and cancer
    • 20495576
    • D.Metcalf. The colony-stimulating factors and cancer. Nat Rev Cancer 2010; 10:425-34; PMID:20495576; http://dx.doi.org/10.1038/nrc2843
    • (2010) Nat Rev Cancer , vol.10 , pp. 425-434
    • Metcalf, D.1
  • 14
    • 33845529437 scopus 로고    scopus 로고
    • Pro-angiogenic cytokines and their role in tumor angiogenesis
    • 17006765
    • G.Neufeld, O.Kessler. Pro-angiogenic cytokines and their role in tumor angiogenesis. Cancer Metastasis Rev 2006; 25:373-85; PMID:17006765; http://dx.doi.org/10.1007/s10555-006-9011-5
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 373-385
    • Neufeld, G.1    Kessler, O.2
  • 15
    • 33747152779 scopus 로고    scopus 로고
    • Cytokines and chemokines as regulators of angiogenesis in health and disease
    • 16918437
    • R.Benelli, G.Lorusso, A.Albini, D.M.Noonan. Cytokines and chemokines as regulators of angiogenesis in health and disease. Curr Pharm Des 2006; 12:3101-15; PMID:16918437; http://dx.doi.org/10.2174/138161206777947461
    • (2006) Curr Pharm Des , vol.12 , pp. 3101-3115
    • Benelli, R.1    Lorusso, G.2    Albini, A.3    Noonan, D.M.4
  • 16
    • 0025225333 scopus 로고
    • Interleukin-1 receptor antagonist reduces mortality from endotoxin shock
    • 2147233
    • K.Ohlsson, P.Bjork, M.Bergenfeldt, R.Hageman, R.C.Thompson. Interleukin-1 receptor antagonist reduces mortality from endotoxin shock. Nature 1990; 348:550-2; PMID:2147233; http://dx.doi.org/10.1038/348550a0
    • (1990) Nature , vol.348 , pp. 550-552
    • Ohlsson, K.1    Bjork, P.2    Bergenfeldt, M.3    Hageman, R.4    Thompson, R.C.5
  • 17
    • 0023491364 scopus 로고
    • Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia
    • 3317066
    • K.J.Tracey, Y.Fong, D.G.Hesse, K.R.Manogue, A.T.Lee, G.C.Kuo, S.F.Lowry, A.Cerami. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature 1987; 330:662-4; PMID:3317066; http://dx.doi.org/10.1038/330662a0
    • (1987) Nature , vol.330 , pp. 662-664
    • Tracey, K.J.1    Fong, Y.2    Hesse, D.G.3    Manogue, K.R.4    Lee, A.T.5    Kuo, G.C.6    Lowry, S.F.7    Cerami, A.8
  • 19
    • 84898035587 scopus 로고    scopus 로고
    • New insights into vertebrate skin regeneration
    • 24725426
    • A.W.Seifert, M.Maden. New insights into vertebrate skin regeneration. Int Rev Cell Mol Biol 2014; 310:129-69; PMID:24725426; http://dx.doi.org/10.1016/B978-0-12-800180-6.00004-9
    • (2014) Int Rev Cell Mol Biol , vol.310 , pp. 129-169
    • Seifert, A.W.1    Maden, M.2
  • 20
  • 21
    • 84925719346 scopus 로고    scopus 로고
    • Regulation of antiviral T cell responses by type I interferons
    • 25790790
    • J.Crouse, U.Kalinke, A.Oxenius. Regulation of antiviral T cell responses by type I interferons. Nat Rev Immunol 2015; 15:231-42; PMID:25790790; http://dx.doi.org/10.1038/nri3806
    • (2015) Nat Rev Immunol , vol.15 , pp. 231-242
    • Crouse, J.1    Kalinke, U.2    Oxenius, A.3
  • 24
    • 84890034987 scopus 로고    scopus 로고
    • Danger signalling during cancer cell death: origins, plasticity and regulation
    • 23686135
    • A.D.Garg, S.Martin, J.Golab, P.Agostinis. Danger signalling during cancer cell death: origins, plasticity and regulation. Cell Death Differ 2014; 21:26-38; PMID:23686135; http://dx.doi.org/10.1038/cdd.2013.48
    • (2014) Cell Death Differ , vol.21 , pp. 26-38
    • Garg, A.D.1    Martin, S.2    Golab, J.3    Agostinis, P.4
  • 26
    • 84906255404 scopus 로고    scopus 로고
    • Immunogenic cell death inducers as anticancer agents
    • 25114034
    • O.Kepp, L.Senovilla, G.Kroemer. Immunogenic cell death inducers as anticancer agents. Oncotarget 2014; 5:5190-1; PMID:25114034; http://dx.doi.org/10.18632/oncotarget.2266
    • (2014) Oncotarget , vol.5 , pp. 5190-5191
    • Kepp, O.1    Senovilla, L.2    Kroemer, G.3
  • 28
    • 84875552922 scopus 로고    scopus 로고
    • Immunogenic cell death in cancer therapy
    • 23157435
    • G.Kroemer, L.Galluzzi, O.Kepp, L.Zitvogel. Immunogenic cell death in cancer therapy. Annu Rev Immunol 2013; 31:51-72; PMID:23157435; http://dx.doi.org/10.1146/annurev-immunol-032712-100008
    • (2013) Annu Rev Immunol , vol.31 , pp. 51-72
    • Kroemer, G.1    Galluzzi, L.2    Kepp, O.3    Zitvogel, L.4
  • 30
    • 84928761118 scopus 로고    scopus 로고
    • Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
    • 25765070
    • N.A.Rizvi, M.D.Hellmann, A.Snyder, P.Kvistborg, V.Makarov, J.J.Havel, W.Lee, J.Yuan, P.Wong, T.S.Ho Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science 2015; 348:124-8; PMID:25765070; http://dx.doi.org/10.1126/science.aaa1348
    • (2015) Science , vol.348 , pp. 124-128
    • Rizvi, N.A.1    Hellmann, M.D.2    Snyder, A.3    Kvistborg, P.4    Makarov, V.5    Havel, J.J.6    Lee, W.7    Yuan, J.8    Wong, P.9    Ho, T.S.10
  • 33
    • 7144227930 scopus 로고    scopus 로고
    • Recombinant human interleukin-2, recombinant human interferon alfa-2a, or both in metastatic renal-cell carcinoma. Groupe Francais d’Immunotherapie
    • 9562581
    • S.Negrier, B.Escudier, C.Lasset, J.Y.Douillard, J.Savary, C.Chevreau, A.Ravaud, A.Mercatello, J.Peny, M.Mousseau Recombinant human interleukin-2, recombinant human interferon alfa-2a, or both in metastatic renal-cell carcinoma. Groupe Francais d’Immunotherapie. N Engl J Med 1998; 338:1272-8; PMID:9562581; http://dx.doi.org/10.1056/NEJM199804303381805
    • (1998) N Engl J Med , vol.338 , pp. 1272-1278
    • Negrier, S.1    Escudier, B.2    Lasset, C.3    Douillard, J.Y.4    Savary, J.5    Chevreau, C.6    Ravaud, A.7    Mercatello, A.8    Peny, J.9    Mousseau, M.10
  • 34
    • 4344656396 scopus 로고    scopus 로고
    • Management of cutaneous melanoma
    • 15342808
    • H.Tsao, M.B.Atkins, A.J.Sober. Management of cutaneous melanoma. N Engl J Med 2004; 351:998-1012; PMID:15342808; http://dx.doi.org/10.1056/NEJMra041245
    • (2004) N Engl J Med , vol.351 , pp. 998-1012
    • Tsao, H.1    Atkins, M.B.2    Sober, A.J.3
  • 35
    • 84896698630 scopus 로고    scopus 로고
    • Cutaneous melanoma
    • 24054424
    • A.M.Eggermont, A.Spatz, C.Robert. Cutaneous melanoma. Lancet 2014; 383:816-27; PMID:24054424; http://dx.doi.org/10.1016/S0140-6736(13)60802-8
    • (2014) Lancet , vol.383 , pp. 816-827
    • Eggermont, A.M.1    Spatz, A.2    Robert, C.3
  • 36
    • 77955538712 scopus 로고    scopus 로고
    • Clinical uses of GM-CSF, a critical appraisal and update
    • 19707424
    • M.Arellano, S.Lonial. Clinical uses of GM-CSF, a critical appraisal and update. Biologics 2008; 2:13-27; PMID:19707424; http://dx.doi.org/10.2147/BTT.S1355
    • (2008) Biologics , vol.2 , pp. 13-27
    • Arellano, M.1    Lonial, S.2
  • 38
    • 84858702393 scopus 로고    scopus 로고
    • A randomised phase II study of the efficacy, safety and cost-effectiveness of pegfilgrastim and filgrastim after autologous stem cell transplant for lymphoma and myeloma (PALM study)
    • 22248711
    • C.Sebban, A.Lefranc, L.Perrier, P.Moreau, D.Espinouse, A.Schmidt, L.Kammoun, H.Ghesquieres, C.Ferlay, J.O.Bay A randomised phase II study of the efficacy, safety and cost-effectiveness of pegfilgrastim and filgrastim after autologous stem cell transplant for lymphoma and myeloma (PALM study). Eur J Cancer 2012; 48:713-20; PMID:22248711; http://dx.doi.org/10.1016/j.ejca.2011.12.016
    • (2012) Eur J Cancer , vol.48 , pp. 713-720
    • Sebban, C.1    Lefranc, A.2    Perrier, L.3    Moreau, P.4    Espinouse, D.5    Schmidt, A.6    Kammoun, L.7    Ghesquieres, H.8    Ferlay, C.9    Bay, J.O.10
  • 39
    • 84934439761 scopus 로고    scopus 로고
    • Hematopoietic stem cell mobilization with G-CSF
    • 22890920
    • C.Hosing. Hematopoietic stem cell mobilization with G-CSF. Methods Mol Biol 2012; 904:37-47; PMID:22890920; http://dx.doi.org/10.1007/978-1-61779-943-3_3
    • (2012) Methods Mol Biol , vol.904 , pp. 37-47
    • Hosing, C.1
  • 40
    • 0036182360 scopus 로고    scopus 로고
    • Mobilization of peripheral blood stem cells with chemotherapy and recombinant human granulocyte colony-stimulating factor (rhG-CSF): a randomized evaluation of different doses of rhG-CSF
    • 11841454
    • T.Demirer, M.Ayli, M.Ozcan, N.Gunel, R.Haznedar, M.Dagli, T.Fen, Y.Genc, S.Dincer, O.Arslan Mobilization of peripheral blood stem cells with chemotherapy and recombinant human granulocyte colony-stimulating factor (rhG-CSF): a randomized evaluation of different doses of rhG-CSF. Br J Haematol 2002; 116:468-74; PMID:11841454; http://dx.doi.org/10.1046/j.1365-2141.2002.03264.x
    • (2002) Br J Haematol , vol.116 , pp. 468-474
    • Demirer, T.1    Ayli, M.2    Ozcan, M.3    Gunel, N.4    Haznedar, R.5    Dagli, M.6    Fen, T.7    Genc, Y.8    Dincer, S.9    Arslan, O.10
  • 41
    • 84871991303 scopus 로고    scopus 로고
    • Pegfilgrastim prophylaxis is associated with a lower risk of hospitalization of cancer patients than filgrastim prophylaxis: a retrospective United States claims analysis of granulocyte colony-stimulating factors (G-CSF)
    • 23298389
    • A.Naeim, H.J.Henk, L.Becker, V.Chia, S.Badre, X.Li, R.Deeter. Pegfilgrastim prophylaxis is associated with a lower risk of hospitalization of cancer patients than filgrastim prophylaxis: a retrospective United States claims analysis of granulocyte colony-stimulating factors (G-CSF). BMC Cancer 2013; 13:11; PMID:23298389; http://dx.doi.org/10.1186/1471-2407-13-11
    • (2013) BMC Cancer , vol.13 , pp. 11
    • Naeim, A.1    Henk, H.J.2    Becker, L.3    Chia, V.4    Badre, S.5    Li, X.6    Deeter, R.7
  • 42
    • 84863902271 scopus 로고    scopus 로고
    • Cost-utility analysis of primary prophylaxis versus secondary prophylaxis with granulocyte colony-stimulating factor in elderly patients with diffuse aggressive lymphoma receiving curative-intent chemotherapy
    • 22393098
    • K.K.Chan, E.Siu, M.D.Krahn, K.Imrie, S.M.Alibhai. Cost-utility analysis of primary prophylaxis versus secondary prophylaxis with granulocyte colony-stimulating factor in elderly patients with diffuse aggressive lymphoma receiving curative-intent chemotherapy. J Clin Oncol 2012; 30:1064-71; PMID:22393098; http://dx.doi.org/10.1200/JCO.2011.36.8647
    • (2012) J Clin Oncol , vol.30 , pp. 1064-1071
    • Chan, K.K.1    Siu, E.2    Krahn, M.D.3    Imrie, K.4    Alibhai, S.M.5
  • 43
    • 84862530664 scopus 로고    scopus 로고
    • Favorable effect of priming with granulocyte colony-stimulating factor in remission induction of acute myeloid leukemia restricted to dose escalation of cytarabine
    • 22422824
    • T.Pabst, E.Vellenga, W.van Putten, H.C.Schouten, C.Graux, M.C.Vekemans, B.Biemond, P.Sonneveld, J.Passweg, L.Verdonck Favorable effect of priming with granulocyte colony-stimulating factor in remission induction of acute myeloid leukemia restricted to dose escalation of cytarabine. Blood 2012; 119:5367-73; PMID:22422824; http://dx.doi.org/10.1182/blood-2011-11-389841
    • (2012) Blood , vol.119 , pp. 5367-5373
    • Pabst, T.1    Vellenga, E.2    van Putten, W.3    Schouten, H.C.4    Graux, C.5    Vekemans, M.C.6    Biemond, B.7    Sonneveld, P.8    Passweg, J.9    Verdonck, L.10
  • 44
    • 80054760660 scopus 로고    scopus 로고
    • Long-term results of tumor necrosis factor alpha- and melphalan-based isolated limb perfusion in locally advanced extremity soft tissue sarcomas
    • 21931039
    • J.P.Deroose, A.M.Eggermont, A.N.van Geel, J.W.Burger, M.A.den Bakker, J.H.de Wilt, C.Verhoef. Long-term results of tumor necrosis factor alpha- and melphalan-based isolated limb perfusion in locally advanced extremity soft tissue sarcomas. J Clin Oncol 2011; 29:4036-44; PMID:21931039; http://dx.doi.org/10.1200/JCO.2011.35.6618
    • (2011) J Clin Oncol , vol.29 , pp. 4036-4044
    • Deroose, J.P.1    Eggermont, A.M.2    van Geel, A.N.3    Burger, J.W.4    den Bakker, M.A.5    de Wilt, J.H.6    Verhoef, C.7
  • 45
    • 84856676019 scopus 로고    scopus 로고
    • 20 years experience of TNF-based isolated limb perfusion for in-transit melanoma metastases: TNF dose matters
    • 21879272
    • J.P.Deroose, A.M.Eggermont, A.N.van Geel, J.H.de Wilt, J.W.Burger, C.Verhoef. 20 years experience of TNF-based isolated limb perfusion for in-transit melanoma metastases: TNF dose matters. Ann Surg Oncol 2012; 19:627-35; PMID:21879272; http://dx.doi.org/10.1245/s10434-011-2030-7
    • (2012) Ann Surg Oncol , vol.19 , pp. 627-635
    • Deroose, J.P.1    Eggermont, A.M.2    van Geel, A.N.3    de Wilt, J.H.4    Burger, J.W.5    Verhoef, C.6
  • 46
    • 80053574336 scopus 로고    scopus 로고
    • Long-term outcome of isolated limb perfusion with tumour necrosis factor-alpha for patients with melanoma in-transit metastases
    • 21739427
    • J.P.Deroose, D.J.Grunhagen, A.N.van Geel, J.H.de Wilt, A.M.Eggermont, C.Verhoef. Long-term outcome of isolated limb perfusion with tumour necrosis factor-alpha for patients with melanoma in-transit metastases. Br J Surg 2011; 98:1573-80; PMID:21739427; http://dx.doi.org/10.1002/bjs.7621
    • (2011) Br J Surg , vol.98 , pp. 1573-1580
    • Deroose, J.P.1    Grunhagen, D.J.2    van Geel, A.N.3    de Wilt, J.H.4    Eggermont, A.M.5    Verhoef, C.6
  • 47
    • 0029958293 scopus 로고    scopus 로고
    • The success of TNF alpha in isolated limb perfusion for irresectable extremity soft tissue sarcomas, melanoma and carcinomas: observations in patients and preclinical perfusion models
    • 8854755
    • A.M.Eggermont. The success of TNF alpha in isolated limb perfusion for irresectable extremity soft tissue sarcomas, melanoma and carcinomas: observations in patients and preclinical perfusion models. Gan To Kagaku Ryoho 1996; 23:1357-70; PMID:8854755
    • (1996) Gan To Kagaku Ryoho , vol.23 , pp. 1357-1370
    • Eggermont, A.M.1
  • 48
    • 0009885824 scopus 로고    scopus 로고
    • Isolated limb perfusion with tumor necrosis factor and melphalan for limb salvage in 186 patients with locally advanced soft tissue extremity sarcomas. The cumulative multicenter European experience
    • discussion 64-5
    • A.M.Eggermont, H.Schraffordt Koops, J.M.Klausner, B.B.Kroon, P.M.Schlag, D.Lienard, A.N.van Geel, H.J.Hoekstra, I.Meller, O.E.Nieweg Isolated limb perfusion with tumor necrosis factor and melphalan for limb salvage in 186 patients with locally advanced soft tissue extremity sarcomas. The cumulative multicenter European experience. Ann Surg 1996; 224:756-64; discussion 64-5; http://dx.doi.org/10.1097/00000658-199612000-00011; PMID:8968230
    • (1996) Ann Surg , vol.224 , pp. 756-764
    • Eggermont, A.M.1    Schraffordt Koops, H.2    Klausner, J.M.3    Kroon, B.B.4    Schlag, P.M.5    Lienard, D.6    van Geel, A.N.7    Hoekstra, H.J.8    Meller, I.9    Nieweg, O.E.10
  • 49
    • 0030625628 scopus 로고    scopus 로고
    • Isolated limb perfusion with high-dose tumor necrosis factor-alpha for locally advanced extremity soft tissue sarcomas
    • 9286497
    • A.M.Eggermont, H.Schraffordt Koops, J.M.Klausner, P.M.Schlag, B.B.Kroon, G.Ben-Ari, F.J.Lejeune. Isolated limb perfusion with high-dose tumor necrosis factor-alpha for locally advanced extremity soft tissue sarcomas. Cancer Treat Res 1997; 91:189-203; PMID:9286497; http://dx.doi.org/10.1007/978-1-4615-6121-7_13
    • (1997) Cancer Treat Res , vol.91 , pp. 189-203
    • Eggermont, A.M.1    Schraffordt Koops, H.2    Klausner, J.M.3    Schlag, P.M.4    Kroon, B.B.5    Ben-Ari, G.6    Lejeune, F.J.7
  • 50
    • 0029738520 scopus 로고    scopus 로고
    • Isolated limb perfusion with high-dose tumor necrosis factor-alpha in combination with interferon-gamma and melphalan for nonresectable extremity soft tissue sarcomas: a multicenter trial
    • 8874324
    • A.M.Eggermont, H.Schraffordt Koops, D.Lienard, B.B.Kroon, A.N.van Geel, H.J.Hoekstra, F.J.Lejeune. Isolated limb perfusion with high-dose tumor necrosis factor-alpha in combination with interferon-gamma and melphalan for nonresectable extremity soft tissue sarcomas: a multicenter trial. J Clin Oncol 1996; 14:2653-65; PMID:8874324
    • (1996) J Clin Oncol , vol.14 , pp. 2653-2665
    • Eggermont, A.M.1    Schraffordt Koops, H.2    Lienard, D.3    Kroon, B.B.4    van Geel, A.N.5    Hoekstra, H.J.6    Lejeune, F.J.7
  • 51
    • 84902590871 scopus 로고    scopus 로고
    • Smac mimetics combined with innate immune stimuli create the perfect cytokine storm to kill tumor cells
    • 25050221
    • S.T.Beug, E.C.LaCasse, R.G.Korneluk. Smac mimetics combined with innate immune stimuli create the perfect cytokine storm to kill tumor cells. Oncoimmunology 2014; 3:e28541; PMID:25050221; http://dx.doi.org/10.4161/onci.28541
    • (2014) Oncoimmunology , vol.3 , pp. 28541
    • Beug, S.T.1    LaCasse, E.C.2    Korneluk, R.G.3
  • 52
    • 84869212118 scopus 로고    scopus 로고
    • Long-term results of the randomized phase III trial EORTC 18991 of adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma
    • 23008300
    • A.M.Eggermont, S.Suciu, A.Testori, M.Santinami, W.H.Kruit, J.Marsden, C.J.Punt, F.Salès, R.Dummer, C.Robert Long-term results of the randomized phase III trial EORTC 18991 of adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma. J Clin Oncol 2012; 30:3810-8; PMID:23008300; http://dx.doi.org/10.1200/JCO.2011.41.3799
    • (2012) J Clin Oncol , vol.30 , pp. 3810-3818
    • Eggermont, A.M.1    Suciu, S.2    Testori, A.3    Santinami, M.4    Kruit, W.H.5    Marsden, J.6    Punt, C.J.7    Salès, F.8    Dummer, R.9    Robert, C.10
  • 53
    • 3142516376 scopus 로고    scopus 로고
    • TNF-based isolated limb perfusion: a decade of experience with antivascular therapy in the management of locally advanced extremity soft tissue sarcomas
    • 15217218
    • D.J.Grunhagen, F.Brunstein, T.L.ten Hagen, A.N.van Geel, J.H.de Wilt, A.M.Eggermont. TNF-based isolated limb perfusion: a decade of experience with antivascular therapy in the management of locally advanced extremity soft tissue sarcomas. Cancer Treat Res 2004; 120:65-79; PMID:15217218; http://dx.doi.org/10.1007/1-4020-7856-0_4
    • (2004) Cancer Treat Res , vol.120 , pp. 65-79
    • Grunhagen, D.J.1    Brunstein, F.2    ten Hagen, T.L.3    van Geel, A.N.4    de Wilt, J.H.5    Eggermont, A.M.6
  • 54
    • 84869412746 scopus 로고    scopus 로고
    • Hyperthermic isolated limb perfusion for extremity soft tissue sarcomas: systematic review of clinical efficacy and quality assessment of reported trials
    • 22806575
    • N.H.Trabulsi, L.Patakfalvi, M.O.Nassif, R.E.Turcotte, A.Nichols, A.N.Meguerditchian. Hyperthermic isolated limb perfusion for extremity soft tissue sarcomas: systematic review of clinical efficacy and quality assessment of reported trials. J Surg Oncol 2012; 106:921-8; PMID:22806575; http://dx.doi.org/10.1002/jso.23200
    • (2012) J Surg Oncol , vol.106 , pp. 921-928
    • Trabulsi, N.H.1    Patakfalvi, L.2    Nassif, M.O.3    Turcotte, R.E.4    Nichols, A.5    Meguerditchian, A.N.6
  • 55
    • 32844472410 scopus 로고    scopus 로고
    • Technology insight: Utility of TNF-alpha-based isolated limb perfusion to avoid amputation of irresectable tumors of the extremities
    • 16462850
    • D.J.Grunhagen, J.H.de Wilt, T.L.ten Hagen, A.M.Eggermont. Technology insight: Utility of TNF-alpha-based isolated limb perfusion to avoid amputation of irresectable tumors of the extremities. Nat Clin Pract Oncol 2006; 3:94-103; PMID:16462850; http://dx.doi.org/10.1038/ncponc0426
    • (2006) Nat Clin Pract Oncol , vol.3 , pp. 94-103
    • Grunhagen, D.J.1    de Wilt, J.H.2    ten Hagen, T.L.3    Eggermont, A.M.4
  • 56
  • 57
    • 0029812542 scopus 로고    scopus 로고
    • Long-term response data for 255 patients with metastatic renal cell carcinoma treated with high-dose recombinant interleukin-2 therapy
    • 8708739
    • G.A.Fyfe, R.I.Fisher, S.A.Rosenberg, M.Sznol, D.R.Parkinson, A.C.Louie. Long-term response data for 255 patients with metastatic renal cell carcinoma treated with high-dose recombinant interleukin-2 therapy. J Clin Oncol 1996; 14:2410-1; PMID:8708739
    • (1996) J Clin Oncol , vol.14 , pp. 2410-2411
    • Fyfe, G.A.1    Fisher, R.I.2    Rosenberg, S.A.3    Sznol, M.4    Parkinson, D.R.5    Louie, A.C.6
  • 58
    • 0028929682 scopus 로고
    • Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy
    • 7884429
    • G.Fyfe, R.I.Fisher, S.A.Rosenberg, M.Sznol, D.R.Parkinson, A.C.Louie. Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy. J Clin Oncol 1995; 13:688-96; PMID:7884429
    • (1995) J Clin Oncol , vol.13 , pp. 688-696
    • Fyfe, G.1    Fisher, R.I.2    Rosenberg, S.A.3    Sznol, M.4    Parkinson, D.R.5    Louie, A.C.6
  • 59
    • 70350580555 scopus 로고    scopus 로고
    • Adjuvant interferon alfa for melanoma: new evidence-based treatment recommendations
    • 19526078
    • A.Hauschild. Adjuvant interferon alfa for melanoma: new evidence-based treatment recommendations? Curr Oncol 2009; 16:3-6; PMID:19526078; http://dx.doi.org/10.3747/co.v16i3.447
    • (2009) Curr Oncol , vol.16 , pp. 3-6
    • Hauschild, A.1
  • 60
    • 0024354157 scopus 로고
    • A phase I/II study of recombinant interferon alpha 2a and hydroxyurea for chronic myelocytic leukemia
    • 2736308
    • B.Anger, F.Porzsolt, R.Leichtle, B.Heinze, C.Bartram, H.Heimpel. A phase I/II study of recombinant interferon alpha 2a and hydroxyurea for chronic myelocytic leukemia. Blut 1989; 58:275-8; PMID:2736308; http://dx.doi.org/10.1007/BF00320165
    • (1989) Blut , vol.58 , pp. 275-278
    • Anger, B.1    Porzsolt, F.2    Leichtle, R.3    Heinze, B.4    Bartram, C.5    Heimpel, H.6
  • 61
    • 0347302952 scopus 로고    scopus 로고
    • Cytokines in cancer pathogenesis and cancer therapy
    • 14708024
    • G.Dranoff. Cytokines in cancer pathogenesis and cancer therapy. Nat Rev Cancer 2004; 4:11-22; PMID:14708024; http://dx.doi.org/10.1038/nrc1252
    • (2004) Nat Rev Cancer , vol.4 , pp. 11-22
    • Dranoff, G.1
  • 62
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • 12490959
    • L.M.Coussens, Z.Werb. Inflammation and cancer. Nature 2002; 420:860-7; PMID:12490959; http://dx.doi.org/10.1038/nature01322
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 63
    • 84872445265 scopus 로고    scopus 로고
    • Neutralizing tumor-promoting chronic inflammation: a magic bullet
    • 23329041
    • L.M.Coussens, L.Zitvogel, A.K.Palucka. Neutralizing tumor-promoting chronic inflammation: a magic bullet? Science 2013; 339:286-91; PMID:23329041; http://dx.doi.org/10.1126/science.1232227
    • (2013) Science , vol.339 , pp. 286-291
    • Coussens, L.M.1    Zitvogel, L.2    Palucka, A.K.3
  • 64
    • 33847758628 scopus 로고    scopus 로고
    • Acute myeloid leukemia or myelodysplastic syndrome following use of granulocyte colony-stimulating factors during breast cancer adjuvant chemotherapy
    • 17284714
    • D.Hershman, A.I.Neugut, J.S.Jacobson, J.Wang, W.Y.Tsai, R.McBride, C.L.Bennett, V.R.Grann. Acute myeloid leukemia or myelodysplastic syndrome following use of granulocyte colony-stimulating factors during breast cancer adjuvant chemotherapy. J Natl Cancer Inst 2007; 99:196-205; PMID:17284714; http://dx.doi.org/10.1093/jnci/djk028
    • (2007) J Natl Cancer Inst , vol.99 , pp. 196-205
    • Hershman, D.1    Neugut, A.I.2    Jacobson, J.S.3    Wang, J.4    Tsai, W.Y.5    McBride, R.6    Bennett, C.L.7    Grann, V.R.8
  • 65
    • 25444485144 scopus 로고    scopus 로고
    • Does the concurrent use of anthracycline and granulocyte colony-stimulating factor influence the risk of secondary leukaemia in breast cancer women?
    • 15857847
    • S.Di Cosimo, G.Ferretti, P.Papaldo, P.Carlini, A.Fabi, E.M.Ruggeri, A.Alimonti, C.Nardoni, F.Cognetti. Does the concurrent use of anthracycline and granulocyte colony-stimulating factor influence the risk of secondary leukaemia in breast cancer women? Ann Oncol 2005; 16:1209-10; PMID:15857847; http://dx.doi.org/10.1093/annonc/mdi201
    • (2005) Ann Oncol , vol.16 , pp. 1209-1210
    • Di Cosimo, S.1    Ferretti, G.2    Papaldo, P.3    Carlini, P.4    Fabi, A.5    Ruggeri, E.M.6    Alimonti, A.7    Nardoni, C.8    Cognetti, F.9
  • 66
    • 0037588995 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor and the risk of secondary myeloid malignancy after etoposide treatment
    • 12531808
    • M.V.Relling, J.M.Boyett, J.G.Blanco, S.Raimondi, F.G.Behm, J.T.Sandlund, G.K.Rivera, L.E.Kun, W.E.Evans, C.H.Pui. Granulocyte colony-stimulating factor and the risk of secondary myeloid malignancy after etoposide treatment. Blood 2003; 101:3862-7; PMID:12531808; http://dx.doi.org/10.1182/blood-2002-08-2405
    • (2003) Blood , vol.101 , pp. 3862-3867
    • Relling, M.V.1    Boyett, J.M.2    Blanco, J.G.3    Raimondi, S.4    Behm, F.G.5    Sandlund, J.T.6    Rivera, G.K.7    Kun, L.E.8    Evans, W.E.9    Pui, C.H.10
  • 67
    • 84908884225 scopus 로고    scopus 로고
    • Centrosomes and the art of mitotic spindle maintenance
    • 25376493
    • E.H.Hinchcliffe. Centrosomes and the art of mitotic spindle maintenance. Int Rev Cell Mol Biol 2014; 313:179-217; PMID:25376493; http://dx.doi.org/10.1016/B978-0-12-800177-6.00006-2
    • (2014) Int Rev Cell Mol Biol , vol.313 , pp. 179-217
    • Hinchcliffe, E.H.1
  • 68
    • 46749103710 scopus 로고    scopus 로고
    • Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial
    • 18620949
    • A.M.Eggermont, S.Suciu, M.Santinami, A.Testori, W.H.Kruit, J.Marsden, C.J.Punt, F.Salès, M.Gore, R.Mackie Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial. Lancet 2008; 372:117-26; PMID:18620949; http://dx.doi.org/10.1016/S0140-6736(08)61033-8
    • (2008) Lancet , vol.372 , pp. 117-126
    • Eggermont, A.M.1    Suciu, S.2    Santinami, M.3    Testori, A.4    Kruit, W.H.5    Marsden, J.6    Punt, C.J.7    Salès, F.8    Gore, M.9    Mackie, R.10
  • 75
    • 84858758766 scopus 로고    scopus 로고
    • Adoptive immunotherapy for cancer: harnessing the T cell response
    • 22437939
    • N.P.Restifo, M.E.Dudley, S.A.Rosenberg. Adoptive immunotherapy for cancer: harnessing the T cell response. Nat Rev Immunol 2012; 12:269-81; PMID:22437939; http://dx.doi.org/10.1038/nri3191
    • (2012) Nat Rev Immunol , vol.12 , pp. 269-281
    • Restifo, N.P.1    Dudley, M.E.2    Rosenberg, S.A.3
  • 76
    • 84884346173 scopus 로고    scopus 로고
    • Adoptive T-cell therapy to treat liver cancer: is the liver microenvironment key
    • 23907631
    • G.Willimsky, U.Protzer, P.Knolle, M.Heikenwalder. Adoptive T-cell therapy to treat liver cancer: is the liver microenvironment key? Oncotarget 2013; 4:1117-8; PMID:23907631; http://dx.doi.org/10.18632/oncotarget.1179
    • (2013) Oncotarget , vol.4 , pp. 1117-1118
    • Willimsky, G.1    Protzer, U.2    Knolle, P.3    Heikenwalder, M.4
  • 79
    • 84906491933 scopus 로고    scopus 로고
    • Cytokine-enhanced intravenous oncolytic virotherapy
    • O.Donnelly, E.Ilett, T.Kottke, J.Thompson, R.Vile, A.Melcher. Cytokine-enhanced intravenous oncolytic virotherapy. Lancet 2014; 383:S4; http://dx.doi.org/10.1016/S0140-6736(14)60305-6
    • (2014) Lancet , vol.383 , pp. 4
    • Donnelly, O.1    Ilett, E.2    Kottke, T.3    Thompson, J.4    Vile, R.5    Melcher, A.6
  • 80
    • 84904999549 scopus 로고    scopus 로고
    • Going viral with cancer immunotherapy
    • 24990523
    • B.D.Lichty, C.J.Breitbach, D.F.Stojdl, J.C.Bell. Going viral with cancer immunotherapy. Nat Rev Cancer 2014; 14:559-67; PMID:24990523; http://dx.doi.org/10.1038/nrc3770
    • (2014) Nat Rev Cancer , vol.14 , pp. 559-567
    • Lichty, B.D.1    Breitbach, C.J.2    Stojdl, D.F.3    Bell, J.C.4
  • 81
    • 84880786463 scopus 로고    scopus 로고
    • Potent antitumor activity of oncolytic adenovirus expressing Beclin-1 via induction of autophagic cell death in leukemia
    • 23765161
    • Y.Tong, L.You, H.Liu, L.Li, H.Meng, Q.Qian, W.Qian. Potent antitumor activity of oncolytic adenovirus expressing Beclin-1 via induction of autophagic cell death in leukemia. Oncotarget 2013; 4:860-74; PMID:23765161; http://dx.doi.org/10.18632/oncotarget.1018
    • (2013) Oncotarget , vol.4 , pp. 860-874
    • Tong, Y.1    You, L.2    Liu, H.3    Li, L.4    Meng, H.5    Qian, Q.6    Qian, W.7
  • 83
    • 84886745437 scopus 로고    scopus 로고
    • Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine
    • 24125763
    • D.H.Hamilton, M.T.Litzinger, A.Jales, B.Huang, R.I.Fernando, J.W.Hodge, A.Ardiani, D.Apelian, J.Schlom, C.Palena. Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine. Oncotarget 2013; 4:1777-90; PMID:24125763; http://dx.doi.org/10.18632/oncotarget.1295
    • (2013) Oncotarget , vol.4 , pp. 1777-1790
    • Hamilton, D.H.1    Litzinger, M.T.2    Jales, A.3    Huang, B.4    Fernando, R.I.5    Hodge, J.W.6    Ardiani, A.7    Apelian, D.8    Schlom, J.9    Palena, C.10
  • 87
    • 84858797296 scopus 로고    scopus 로고
    • The determinants of tumour immunogenicity
    • 22378190
    • T.Blankenstein, P.G.Coulie, E.Gilboa, E.M.Jaffee. The determinants of tumour immunogenicity. Nat Rev Cancer 2012; 12:307-13; PMID:22378190; http://dx.doi.org/10.1038/nrc3246
    • (2012) Nat Rev Cancer , vol.12 , pp. 307-313
    • Blankenstein, T.1    Coulie, P.G.2    Gilboa, E.3    Jaffee, E.M.4
  • 88
    • 84880721353 scopus 로고    scopus 로고
    • Dendritic-cell-based therapeutic cancer vaccines
    • 23890062
    • K.Palucka, J.Banchereau. Dendritic-cell-based therapeutic cancer vaccines. Immunity 2013; 39:38-48; PMID:23890062; http://dx.doi.org/10.1016/j.immuni.2013.07.004
    • (2013) Immunity , vol.39 , pp. 38-48
    • Palucka, K.1    Banchereau, J.2
  • 91
    • 34748886192 scopus 로고    scopus 로고
    • Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting
    • 17853902
    • P.J.Tacken, I.J.de Vries, R.Torensma, C.G.Figdor. Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting. Nat Rev Immunol 2007; 7:790-802; PMID:17853902; http://dx.doi.org/10.1038/nri2173
    • (2007) Nat Rev Immunol , vol.7 , pp. 790-802
    • Tacken, P.J.1    de Vries, I.J.2    Torensma, R.3    Figdor, C.G.4
  • 92
    • 84858780815 scopus 로고    scopus 로고
    • Cancer immunotherapy via dendritic cells
    • 22437871
    • K.Palucka, J.Banchereau. Cancer immunotherapy via dendritic cells. Nat Rev Cancer 2012; 12:265-77; PMID:22437871; http://dx.doi.org/10.1038/nrc3258
    • (2012) Nat Rev Cancer , vol.12 , pp. 265-277
    • Palucka, K.1    Banchereau, J.2
  • 93
    • 84930458221 scopus 로고    scopus 로고
    • Cancer-derived immunoglobulin G promotes LPS-induced proinflammatory cytokine production via binding to TLR4 in cervical cancer cells
    • 25179302
    • J.Wang, D.Lin, H.Peng, J.Shao, J.Gu. Cancer-derived immunoglobulin G promotes LPS-induced proinflammatory cytokine production via binding to TLR4 in cervical cancer cells. Oncotarget 2014; 5:9727-43; PMID:25179302; http://dx.doi.org/10.18632/oncotarget.2359
    • (2014) Oncotarget , vol.5 , pp. 9727-9743
    • Wang, J.1    Lin, D.2    Peng, H.3    Shao, J.4    Gu, J.5
  • 94
    • 84898623928 scopus 로고    scopus 로고
    • Targeting aerobic glycolysis and HIF-1alpha expression enhance imiquimod-induced apoptosis in cancer cells
    • 24658058
    • S.W.Huang, J.K.Kao, C.Y.Wu, S.T.Wang, H.C.Lee, S.M.Liang, Y.J.Chen, J.J.Shieh. Targeting aerobic glycolysis and HIF-1alpha expression enhance imiquimod-induced apoptosis in cancer cells. Oncotarget 2014; 5:1363-81; PMID:24658058; http://dx.doi.org/10.18632/oncotarget.1734
    • (2014) Oncotarget , vol.5 , pp. 1363-1381
    • Huang, S.W.1    Kao, J.K.2    Wu, C.Y.3    Wang, S.T.4    Lee, H.C.5    Liang, S.M.6    Chen, Y.J.7    Shieh, J.J.8
  • 97
    • 57849159061 scopus 로고    scopus 로고
    • Toll-like receptors and cancer
    • 19052556
    • S.Rakoff-Nahoum, R.Medzhitov. Toll-like receptors and cancer. Nat Rev Cancer 2009; 9:57-63; PMID:19052556; http://dx.doi.org/10.1038/nrc2541
    • (2009) Nat Rev Cancer , vol.9 , pp. 57-63
    • Rakoff-Nahoum, S.1    Medzhitov, R.2
  • 98
    • 84925452652 scopus 로고    scopus 로고
    • A phase II study of a dose-density regimen with fluorouracil, epirubicin, and cyclophosphamide on days 1 and 4 every 14 days with filgrastim support followed by weekly paclitaxel in women with primary breast cancer
    • 25637379
    • E.Pietri, D.Andreis, F.Fabbri, C.Menna, A.Schirone, B.Kopf, A.Rocca, D.Amadori, U.De Giorgi. A phase II study of a dose-density regimen with fluorouracil, epirubicin, and cyclophosphamide on days 1 and 4 every 14 days with filgrastim support followed by weekly paclitaxel in women with primary breast cancer. Oncologist 2015; 20:239-40; PMID:25637379; http://dx.doi.org/10.1634/theoncologist.2014-0326
    • (2015) Oncologist , vol.20 , pp. 239-240
    • Pietri, E.1    Andreis, D.2    Fabbri, F.3    Menna, C.4    Schirone, A.5    Kopf, B.6    Rocca, A.7    Amadori, D.8    De Giorgi, U.9
  • 99
    • 84932155448 scopus 로고    scopus 로고
    • Efficacy of hepatic arterial infusion chemotherapy using 5-fluorouracil and systemic pegylated interferon alpha-2b for advanced intrahepatic cholangiocarcinoma
    • 24817369
    • K.Kasai, Y.Kooka, Y.Suzuki, A.Suzuki, T.Oikawa, A.Ushio, Y.Kasai, K.Sawara, Y.Miyamoto, K.Oikawa Efficacy of hepatic arterial infusion chemotherapy using 5-fluorouracil and systemic pegylated interferon alpha-2b for advanced intrahepatic cholangiocarcinoma. Ann Surg Oncol 2014; 21:3638-45; PMID:24817369; http://dx.doi.org/10.1245/s10434-014-3766-7
    • (2014) Ann Surg Oncol , vol.21 , pp. 3638-3645
    • Kasai, K.1    Kooka, Y.2    Suzuki, Y.3    Suzuki, A.4    Oikawa, T.5    Ushio, A.6    Kasai, Y.7    Sawara, K.8    Miyamoto, Y.9    Oikawa, K.10
  • 100
    • 84930673064 scopus 로고    scopus 로고
    • Dose-finding/phase II trial: bevacizumab, immunotherapy, and chemotherapy (BIC) in metastatic renal cell cancer (mRCC). Antitumor effects and variations of circulating T regulatory cells (Treg)
    • 25230695
    • M.Donini, S.Buti, S.Lazzarelli, R.Bozzetti, L.Rivoltini, C.Camisaschi, C.Castelli, A.Bearz, C.Simonelli, G.Lo Re Dose-finding/phase II trial: bevacizumab, immunotherapy, and chemotherapy (BIC) in metastatic renal cell cancer (mRCC). Antitumor effects and variations of circulating T regulatory cells (Treg). Target Oncol 2015; 10:277-86; PMID:25230695; http://dx.doi.org/10.1007/s11523-014-0337-6
    • (2015) Target Oncol , vol.10 , pp. 277-286
    • Donini, M.1    Buti, S.2    Lazzarelli, S.3    Bozzetti, R.4    Rivoltini, L.5    Camisaschi, C.6    Castelli, C.7    Bearz, A.8    Simonelli, C.9    Lo Re, G.10
  • 101
    • 84907193462 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony stimulating factor (GM-CSF) enhances the clinical responses to interferon-alpha (IFN) in newly diagnosed chronic myeloid leukemia (CML)
    • 25012565
    • J.F.Zeidner, D.E.Gladstone, M.Zahurak, W.H.Matsui, C.Gocke, R.J.Jones, B.D.Smith. Granulocyte-macrophage colony stimulating factor (GM-CSF) enhances the clinical responses to interferon-alpha (IFN) in newly diagnosed chronic myeloid leukemia (CML). Leuk Res 2014; 38:886-90; PMID:25012565; http://dx.doi.org/10.1016/j.leukres.2014.05.012
    • (2014) Leuk Res , vol.38 , pp. 886-890
    • Zeidner, J.F.1    Gladstone, D.E.2    Zahurak, M.3    Matsui, W.H.4    Gocke, C.5    Jones, R.J.6    Smith, B.D.7
  • 102
    • 84920540809 scopus 로고    scopus 로고
    • Therapeutic DC vaccination with IL-2 as a consolidation therapy for ovarian cancer patients: a phase I/II trial
    • 24976269
    • S.Baek, Y.M.Kim, S.B.Kim, C.S.Kim, S.W.Kwon, Y.Kim, H.Kim, H.Lee. Therapeutic DC vaccination with IL-2 as a consolidation therapy for ovarian cancer patients: a phase I/II trial. Cell Mol Immunol 2015; 12:87-95; PMID:24976269; http://dx.doi.org/10.1038/cmi.2014.40
    • (2015) Cell Mol Immunol , vol.12 , pp. 87-95
    • Baek, S.1    Kim, Y.M.2    Kim, S.B.3    Kim, C.S.4    Kwon, S.W.5    Kim, Y.6    Kim, H.7    Lee, H.8
  • 103
    • 84929130686 scopus 로고    scopus 로고
    • Intermittent chemotherapy as a platform for testing novel agents in patients with metastatic castration-resistant prostate cancer: A department of defense prostate cancer clinical trials consortium randomized phase II trial of intermittent docetaxel with prednisone with or without maintenance GM-CSF
    • 25557266
    • R.R.Aggarwal, T.M.Beer, V.K.Weinberg, C.Higano, M.E.Taplin, C.J.Ryan, A.M.Lin, J.Alumkal, J.N.Graff, L.T.Nordquist Intermittent chemotherapy as a platform for testing novel agents in patients with metastatic castration-resistant prostate cancer: A department of defense prostate cancer clinical trials consortium randomized phase II trial of intermittent docetaxel with prednisone with or without maintenance GM-CSF. Clin Genitourin Cancer 2015; 13:e191-8; PMID:25557266; http://dx.doi.org/10.1016/j.clgc.2014.12.004
    • (2015) Clin Genitourin Cancer , vol.13 , pp. 8
    • Aggarwal, R.R.1    Beer, T.M.2    Weinberg, V.K.3    Higano, C.4    Taplin, M.E.5    Ryan, C.J.6    Lin, A.M.7    Alumkal, J.8    Graff, J.N.9    Nordquist, L.T.10
  • 104
    • 84939471750 scopus 로고    scopus 로고
    • The tumor-targeting immunocytokine F16-IL2 in combination with doxorubicin: dose escalation in patients with advanced solid tumors and expansion into patients with metastatic breast cancer
    • 25562532
    • C.Catania, M.Maur, R.Berardi, A.Rocca, A.M.Giacomo, G.Spitaleri, C.Masini, C.Pierantoni, R.González-Iglesias, G.Zigon The tumor-targeting immunocytokine F16-IL2 in combination with doxorubicin: dose escalation in patients with advanced solid tumors and expansion into patients with metastatic breast cancer. Cell Adh Migr 2015; 9:14-21; PMID:25562532; http://dx.doi.org/10.4161/19336918.2014.983785
    • (2015) Cell Adh Migr , vol.9 , pp. 14-21
    • Catania, C.1    Maur, M.2    Berardi, R.3    Rocca, A.4    Giacomo, A.M.5    Spitaleri, G.6    Masini, C.7    Pierantoni, C.8    González-Iglesias, R.9    Zigon, G.10
  • 105
    • 84924255334 scopus 로고    scopus 로고
    • Immunological response and overall survival in a subset of advanced renal cell carcinoma patients from a randomized phase 2/3 study of naptumomab estafenatox plus IFN-alpha versus IFN-alpha
    • 25669986
    • E.Elkord, D.J.Burt, A.Sundstedt, O.Nordle, G.Hedlund, R.E.Hawkins. Immunological response and overall survival in a subset of advanced renal cell carcinoma patients from a randomized phase 2/3 study of naptumomab estafenatox plus IFN-alpha versus IFN-alpha. Oncotarget 2015; 6:4428-39; PMID:25669986; http://dx.doi.org/10.18632/oncotarget.2922
    • (2015) Oncotarget , vol.6 , pp. 4428-4439
    • Elkord, E.1    Burt, D.J.2    Sundstedt, A.3    Nordle, O.4    Hedlund, G.5    Hawkins, R.E.6
  • 106
    • 84941807191 scopus 로고    scopus 로고
    • Long-term outcome of patients with frequently recurrent non-muscle-invasive bladder carcinoma treated with one perioperative plus four weekly instillations of mitomycin C followed by monthly bacillus calmette-guerin (BCG) or alternating BCG and interferon-alpha2b instillations: Prospective randomised finnBladder-4 study
    • 25748117
    • R.Jarvinen, T.Marttila, E.Kaasinen, E.Rintala, S.Aaltomaa, J.Kallio, T.Liukkonen, V.M.Puolakka, M.Seppänen, K.Tuhkanen Long-term outcome of patients with frequently recurrent non-muscle-invasive bladder carcinoma treated with one perioperative plus four weekly instillations of mitomycin C followed by monthly bacillus calmette-guerin (BCG) or alternating BCG and interferon-alpha2b instillations: Prospective randomised finnBladder-4 study. Eur Urol 2015; 68:611-7; PMID:25748117; http://dx.doi.org/10.1016/j.eururo.2015.02.022
    • (2015) Eur Urol , vol.68 , pp. 611-617
    • Jarvinen, R.1    Marttila, T.2    Kaasinen, E.3    Rintala, E.4    Aaltomaa, S.5    Kallio, J.6    Liukkonen, T.7    Puolakka, V.M.8    Seppänen, M.9    Tuhkanen, K.10
  • 107
    • 84946049367 scopus 로고    scopus 로고
    • Two courses of four weekly infusions of rituximab with or without interferon-alpha2a: final results from a randomized phase III study in symptomatic indolent B-cell lymphomas
    • E.Kimby, B.Ostenstad, P.Brown, H.Hagberg, M.Erlanson, H.Holte, O.Linden, A.S.Johansson, T.Ahlgren, K.Wader Two courses of four weekly infusions of rituximab with or without interferon-alpha2a: final results from a randomized phase III study in symptomatic indolent B-cell lymphomas. Leuk Lymphoma 2015; 56:2598-607; PMID:25686644; http://dx.doi.org/10.3109/10428194.2015.1014363
    • (2015) Leuk Lymphoma
    • Kimby, E.1    Ostenstad, B.2    Brown, P.3    Hagberg, H.4    Erlanson, M.5    Holte, H.6    Linden, O.7    Johansson, A.S.8    Ahlgren, T.9    Wader, K.10
  • 108
    • 84937900491 scopus 로고    scopus 로고
    • RECORD-2: phase II randomized study of everolimus and bevacizumab versus interferon alpha-2a and bevacizumab as first-line therapy in patients with metastatic renal cell carcinoma
    • 25851632
    • A.Ravaud, C.H.Barrios, B.Alekseev, M.H.Tay, S.S.Agarwala, S.Yalcin, C.C.Lin, L.Roman, M.Shkolnik, O.Anak RECORD-2: phase II randomized study of everolimus and bevacizumab versus interferon alpha-2a and bevacizumab as first-line therapy in patients with metastatic renal cell carcinoma. Ann Oncol 2015; 26:1378-84; PMID:25851632; http://dx.doi.org/10.1093/annonc/mdv149
    • (2015) Ann Oncol , vol.26 , pp. 1378-1384
    • Ravaud, A.1    Barrios, C.H.2    Alekseev, B.3    Tay, M.H.4    Agarwala, S.S.5    Yalcin, S.6    Lin, C.C.7    Roman, L.8    Shkolnik, M.9    Anak, O.10
  • 109
    • 84962016429 scopus 로고    scopus 로고
    • Single Institution Experience of Ipilimumab 3 mg/kg with Sargramostim (GM-CSF) in Metastatic Melanoma
    • 25943535
    • J.J.Luke, H.Donahue, M.Nishino, A.Giobbie-Hurder, M.Davis, N.Bailey, P.A.Ott, F.S.Hodi. Single Institution Experience of Ipilimumab 3 mg/kg with Sargramostim (GM-CSF) in Metastatic Melanoma. Cancer Immunol Res 2015; 3:986-91; PMID:25943535; http://dx.doi.org/10.1158/2326-6066.CIR-15-0066
    • (2015) Cancer Immunol Res , vol.3 , pp. 986-991
    • Luke, J.J.1    Donahue, H.2    Nishino, M.3    Giobbie-Hurder, A.4    Davis, M.5    Bailey, N.6    Ott, P.A.7    Hodi, F.S.8
  • 110
    • 84937525789 scopus 로고    scopus 로고
    • Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial
    • 26095785
    • E.B.Golden, A.Chhabra, A.Chachoua, S.Adams, M.Donach, M.Fenton-Kerimian, K.Friedman, F.Ponzo, J.S.Babb, J.Goldberg Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial. Lancet Oncol 2015; 16:795-803; PMID:26095785; http://dx.doi.org/10.1016/S1470-2045(15)00054-6
    • (2015) Lancet Oncol , vol.16 , pp. 795-803
    • Golden, E.B.1    Chhabra, A.2    Chachoua, A.3    Adams, S.4    Donach, M.5    Fenton-Kerimian, M.6    Friedman, K.7    Ponzo, F.8    Babb, J.S.9    Goldberg, J.10
  • 111
    • 84959353831 scopus 로고    scopus 로고
    • Phase II trial of granulocyte-macrophage colony-stimulating factor plus thalidomide in older patients with castration-resistant prostate cancer
    • 26171197
    • L.Song, X.Zhou, X.Li. Phase II trial of granulocyte-macrophage colony-stimulating factor plus thalidomide in older patients with castration-resistant prostate cancer. Mol Clin Oncol 2015; 3:865-8; PMID:26171197; http://dx.doi.org/10.3892/mco.2015.571
    • (2015) Mol Clin Oncol , vol.3 , pp. 865-868
    • Song, L.1    Zhou, X.2    Li, X.3
  • 112
    • 84943791915 scopus 로고    scopus 로고
    • A phase I trial combining carboplatin/doxorubicin with tocilizumab, an anti-IL-6R monoclonal antibody, and interferon-alpha2b in patients with recurrent epithelial ovarian cancer
    • 26216383
    • E.M.Dijkgraaf, S.J.Santegoets, A.K.Reyners, R.Goedemans, M.C.Wouters, G.G.Kenter, A.R.van Erkel, M.I.van Poelgeest, H.W.Nijman, J.J.van der Hoeven A phase I trial combining carboplatin/doxorubicin with tocilizumab, an anti-IL-6R monoclonal antibody, and interferon-alpha2b in patients with recurrent epithelial ovarian cancer. Ann Oncol 2015; 26:2141-9; PMID:26216383; http://dx.doi.org/10.1093/annonc/mdv309
    • (2015) Ann Oncol , vol.26 , pp. 2141-2149
    • Dijkgraaf, E.M.1    Santegoets, S.J.2    Reyners, A.K.3    Goedemans, R.4    Wouters, M.C.5    Kenter, G.G.6    van Erkel, A.R.7    van Poelgeest, M.I.8    Nijman, H.W.9    van der Hoeven, J.J.10
  • 113
    • 84943818598 scopus 로고    scopus 로고
    • Phase II clinical trial of sorafenib plus interferon-alpha treatment for patients with metastatic renal cell carcinoma in Japan
    • 26452347
    • M.Eto, Y.Kawano, Y.Hirao, K.Mita, Y.Arai, T.Tsukamoto, K.Hashine, A.Matsubara, T.Fujioka, G.Kimura Phase II clinical trial of sorafenib plus interferon-alpha treatment for patients with metastatic renal cell carcinoma in Japan. BMC Cancer 2015; 15:667; PMID:26452347; http://dx.doi.org/10.1186/s12885-015-1675-1
    • (2015) BMC Cancer , vol.15 , pp. 667
    • Eto, M.1    Kawano, Y.2    Hirao, Y.3    Mita, K.4    Arai, Y.5    Tsukamoto, T.6    Hashine, K.7    Matsubara, A.8    Fujioka, T.9    Kimura, G.10
  • 114
    • 84920577302 scopus 로고    scopus 로고
    • Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer
    • 25403209
    • K.C.Conlon, E.Lugli, H.C.Welles, S.A.Rosenberg, A.T.Fojo, J.C.Morris, T.A.Fleisher, S.P.Dubois, L.P.Perera, D.M.Stewart Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer. J Clin Oncol 2015; 33:74-82; PMID:25403209; http://dx.doi.org/10.1200/JCO.2014.57.3329
    • (2015) J Clin Oncol , vol.33 , pp. 74-82
    • Conlon, K.C.1    Lugli, E.2    Welles, H.C.3    Rosenberg, S.A.4    Fojo, A.T.5    Morris, J.C.6    Fleisher, T.A.7    Dubois, S.P.8    Perera, L.P.9    Stewart, D.M.10
  • 115
    • 84885786463 scopus 로고    scopus 로고
    • New immunotherapeutic paradigms for castration-resistant prostate cancer
    • L.Galluzzi. New immunotherapeutic paradigms for castration-resistant prostate cancer. Oncoimmunology 2013; 2:e26084; http://dx.doi.org/10.4161/onci.26084
    • (2013) Oncoimmunology , vol.2 , pp. 26084
    • Galluzzi, L.1
  • 116
    • 84899051541 scopus 로고    scopus 로고
    • Novel insights into the mechanism of action of lenalidomide
    • 25340011
    • M.Semeraro, L.Galluzzi. Novel insights into the mechanism of action of lenalidomide. Oncoimmunology 2014; 3:e28386; PMID:25340011; http://dx.doi.org/10.4161/onci.28386
    • (2014) Oncoimmunology , vol.3 , pp. 28386
    • Semeraro, M.1    Galluzzi, L.2
  • 119
    • 84896724517 scopus 로고    scopus 로고
    • Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing
    • 24480782
    • S.R.Gameiro, M.L.Jammeh, M.M.Wattenberg, K.Y.Tsang, S.Ferrone, J.W.Hodge. Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing. Oncotarget 2014; 5:403-16; PMID:24480782; http://dx.doi.org/10.18632/oncotarget.1719
    • (2014) Oncotarget , vol.5 , pp. 403-416
    • Gameiro, S.R.1    Jammeh, M.L.2    Wattenberg, M.M.3    Tsang, K.Y.4    Ferrone, S.5    Hodge, J.W.6
  • 121
    • 84904987878 scopus 로고    scopus 로고
    • Intrinsic bevacizumab resistance is associated with prolonged activation of autocrine VEGF signaling and hypoxia tolerance in colorectal cancer cells and can be overcome by nintedanib, a small molecule angiokinase inhibitor
    • 25015210
    • P.Mesange, V.Poindessous, M.Sabbah, A.E.Escargueil, A.de Gramont, A.K.Larsen. Intrinsic bevacizumab resistance is associated with prolonged activation of autocrine VEGF signaling and hypoxia tolerance in colorectal cancer cells and can be overcome by nintedanib, a small molecule angiokinase inhibitor. Oncotarget 2014; 5:4709-21; PMID:25015210; http://dx.doi.org/10.18632/oncotarget.1671
    • (2014) Oncotarget , vol.5 , pp. 4709-4721
    • Mesange, P.1    Poindessous, V.2    Sabbah, M.3    Escargueil, A.E.4    de Gramont, A.5    Larsen, A.K.6
  • 123
    • 84872387034 scopus 로고    scopus 로고
    • Role of macrophage polarization in tumor angiogenesis and vessel normalization: implications for new anticancer therapies
    • 23317816
    • P.Chen, P.Bonaldo. Role of macrophage polarization in tumor angiogenesis and vessel normalization: implications for new anticancer therapies. Int Rev Cell Mol Biol 2013; 301:1-35; PMID:23317816; http://dx.doi.org/10.1016/B978-0-12-407704-1.00001-4
    • (2013) Int Rev Cell Mol Biol , vol.301 , pp. 1-35
    • Chen, P.1    Bonaldo, P.2
  • 124
    • 84886739659 scopus 로고    scopus 로고
    • Notch3 inhibition enhances sorafenib cytotoxic efficacy by promoting GSK3b phosphorylation and p21 down-regulation in hepatocellular carcinoma
    • 24113128
    • C.Giovannini, M.Baglioni, M.Baron Toaldo, C.Ventrucci, S.D’Adamo, M.Cipone, P.Chieco, L.Gramantieri, L.Bolondi. Notch3 inhibition enhances sorafenib cytotoxic efficacy by promoting GSK3b phosphorylation and p21 down-regulation in hepatocellular carcinoma. Oncotarget 2013; 4:1618-31; PMID:24113128; http://dx.doi.org/10.18632/oncotarget.1221
    • (2013) Oncotarget , vol.4 , pp. 1618-1631
    • Giovannini, C.1    Baglioni, M.2    Baron Toaldo, M.3    Ventrucci, C.4    D’Adamo, S.5    Cipone, M.6    Chieco, P.7    Gramantieri, L.8    Bolondi, L.9
  • 125
    • 84867517513 scopus 로고    scopus 로고
    • Sorafenib has potent antitumor activity against multiple myeloma in vitro, ex vivo, and in vivo in the 5T33MM mouse model
    • 22952216
    • P.Kharaziha, H.De Raeve, C.Fristedt, Q.Li, A.Gruber, P.Johnsson, G.Kokaraki, M.Panzar, E.Laane, A.Osterborg Sorafenib has potent antitumor activity against multiple myeloma in vitro, ex vivo, and in vivo in the 5T33MM mouse model. Cancer Res 2012; 72:5348-62; PMID:22952216; http://dx.doi.org/10.1158/0008-5472.CAN-12-0658
    • (2012) Cancer Res , vol.72 , pp. 5348-5362
    • Kharaziha, P.1    De Raeve, H.2    Fristedt, C.3    Li, Q.4    Gruber, A.5    Johnsson, P.6    Kokaraki, G.7    Panzar, M.8    Laane, E.9    Osterborg, A.10
  • 126
    • 84880747672 scopus 로고    scopus 로고
    • Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance
    • 23890065
    • L.Zitvogel, L.Galluzzi, M.J.Smyth, G.Kroemer. Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance. Immunity 2013; 39:74-88; PMID:23890065; http://dx.doi.org/10.1016/j.immuni.2013.06.014
    • (2013) Immunity , vol.39 , pp. 74-88
    • Zitvogel, L.1    Galluzzi, L.2    Smyth, M.J.3    Kroemer, G.4
  • 129
    • 84899630091 scopus 로고    scopus 로고
    • Randomized phase III trial of temsirolimus and bevacizumab versus interferon alfa and bevacizumab in metastatic renal cell carcinoma: INTORACT trial
    • 24297945
    • B.I.Rini, J.Bellmunt, J.Clancy, K.Wang, A.G.Niethammer, S.Hariharan, B.Escudier. Randomized phase III trial of temsirolimus and bevacizumab versus interferon alfa and bevacizumab in metastatic renal cell carcinoma: INTORACT trial. J Clin Oncol 2014; 32:752-9; PMID:24297945; http://dx.doi.org/10.1200/JCO.2013.50.5305
    • (2014) J Clin Oncol , vol.32 , pp. 752-759
    • Rini, B.I.1    Bellmunt, J.2    Clancy, J.3    Wang, K.4    Niethammer, A.G.5    Hariharan, S.6    Escudier, B.7
  • 130
    • 84907482157 scopus 로고    scopus 로고
    • Clinical outcomes of a novel combination of lenalidomide and rituximab followed by stem cell transplantation for relapsed/refractory aggressive B-cell non-hodgkin lymphoma
    • 25228589
    • Q.Cai, Y.Chen, D.Zou, L.Zhang, M.Badillo, S.Zhou, E.Lopez, W.Jiang, H.Huang, T.Lin Clinical outcomes of a novel combination of lenalidomide and rituximab followed by stem cell transplantation for relapsed/refractory aggressive B-cell non-hodgkin lymphoma. Oncotarget 2014; 5:7368-80; PMID:25228589; http://dx.doi.org/10.18632/oncotarget.2255
    • (2014) Oncotarget , vol.5 , pp. 7368-7380
    • Cai, Q.1    Chen, Y.2    Zou, D.3    Zhang, L.4    Badillo, M.5    Zhou, S.6    Lopez, E.7    Jiang, W.8    Huang, H.9    Lin, T.10
  • 131
    • 84880846935 scopus 로고    scopus 로고
    • Myeloablative anti-CD20 radioimmunotherapy +/- high-dose chemotherapy followed by autologous stem cell support for relapsed/refractory B-cell lymphoma results in excellent long-term survival
    • 23765188
    • J.Y.Wagner, K.Schwarz, S.Schreiber, B.Schmidt, H.J.Wester, M.Schwaiger, C.Peschel, C.von Schilling, K.Scheidhauer, U.Keller. Myeloablative anti-CD20 radioimmunotherapy +/- high-dose chemotherapy followed by autologous stem cell support for relapsed/refractory B-cell lymphoma results in excellent long-term survival. Oncotarget 2013; 4:899-910; PMID:23765188; http://dx.doi.org/10.18632/oncotarget.1037
    • (2013) Oncotarget , vol.4 , pp. 899-910
    • Wagner, J.Y.1    Schwarz, K.2    Schreiber, S.3    Schmidt, B.4    Wester, H.J.5    Schwaiger, M.6    Peschel, C.7    von Schilling, C.8    Scheidhauer, K.9    Keller, U.10
  • 132
    • 84905046220 scopus 로고    scopus 로고
    • The antihypertension drug doxazosin inhibits tumor growth and angiogenesis by decreasing VEGFR-2/Akt/mTOR signaling and VEGF and HIF-1alpha expression
    • 24952732
    • M.S.Park, B.R.Kim, S.M.Dong, S.H.Lee, D.Y.Kim, S.B.Rho. The antihypertension drug doxazosin inhibits tumor growth and angiogenesis by decreasing VEGFR-2/Akt/mTOR signaling and VEGF and HIF-1alpha expression. Oncotarget 2014; 5:4935-44; PMID:24952732; http://dx.doi.org/10.18632/oncotarget.2064
    • (2014) Oncotarget , vol.5 , pp. 4935-4944
    • Park, M.S.1    Kim, B.R.2    Dong, S.M.3    Lee, S.H.4    Kim, D.Y.5    Rho, S.B.6
  • 133
    • 84894553603 scopus 로고    scopus 로고
    • Immunosuppressants in cancer prevention and therapy
    • 24575379
    • M.V.Blagosklonny. Immunosuppressants in cancer prevention and therapy. Oncoimmunology 2013; 2:e26961; PMID:24575379; http://dx.doi.org/10.4161/onci.26961
    • (2013) Oncoimmunology , vol.2 , pp. 26961
    • Blagosklonny, M.V.1
  • 136
  • 137
    • 84901256936 scopus 로고    scopus 로고
    • Interleukin-17D mediates tumor rejection through recruitment of natural killer cells
    • 24794441
    • T.O’Sullivan, R.Saddawi-Konefka, E.Gross, M.Tran, S.P.Mayfield, H.Ikeda, J.D.Bui. Interleukin-17D mediates tumor rejection through recruitment of natural killer cells. Cell Rep 2014; 7:989-98; PMID:24794441; http://dx.doi.org/10.1016/j.celrep.2014.03.073
    • (2014) Cell Rep , vol.7 , pp. 989-998
    • O’Sullivan, T.1    Saddawi-Konefka, R.2    Gross, E.3    Tran, M.4    Mayfield, S.P.5    Ikeda, H.6    Bui, J.D.7
  • 138
    • 84928013457 scopus 로고    scopus 로고
    • Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2
    • 25873172
    • E.F.Zhu, S.A.Gai, C.F.Opel, B.H.Kwan, R.Surana, M.C.Mihm, M.J.Kauke, K.D.Moynihan, A.Angelini, R.T.Williams Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2. Cancer Cell 2015; 27:489-501; PMID:25873172; http://dx.doi.org/10.1016/j.ccell.2015.03.004
    • (2015) Cancer Cell , vol.27 , pp. 489-501
    • Zhu, E.F.1    Gai, S.A.2    Opel, C.F.3    Kwan, B.H.4    Surana, R.5    Mihm, M.C.6    Kauke, M.J.7    Moynihan, K.D.8    Angelini, A.9    Williams, R.T.10
  • 139
    • 84912089439 scopus 로고    scopus 로고
    • Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells
    • 25446896
    • B.Ruffell, D.Chang-Strachan, V.Chan, A.Rosenbusch, C.M.Ho, N.Pryer, D.Daniel, E.S.Hwang, H.S.Rugo, L.M.Coussens. Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells. Cancer Cell 2014; 26:623-37; PMID:25446896; http://dx.doi.org/10.1016/j.ccell.2014.09.006
    • (2014) Cancer Cell , vol.26 , pp. 623-637
    • Ruffell, B.1    Chang-Strachan, D.2    Chan, V.3    Rosenbusch, A.4    Ho, C.M.5    Pryer, N.6    Daniel, D.7    Hwang, E.S.8    Rugo, H.S.9    Coussens, L.M.10
  • 140
    • 84892434546 scopus 로고    scopus 로고
    • Hepatic RIG-I predicts survival and interferon-alpha therapeutic response in hepatocellular carcinoma
    • 24360797
    • J.Hou, Y.Zhou, Y.Zheng, J.Fan, W.Zhou, I.O.Ng, H.Sun, L.Qin, S.Qiu, J.M.Lee Hepatic RIG-I predicts survival and interferon-alpha therapeutic response in hepatocellular carcinoma. Cancer Cell 2014; 25:49-63; PMID:24360797; http://dx.doi.org/10.1016/j.ccr.2013.11.011
    • (2014) Cancer Cell , vol.25 , pp. 49-63
    • Hou, J.1    Zhou, Y.2    Zheng, Y.3    Fan, J.4    Zhou, W.5    Ng, I.O.6    Sun, H.7    Qin, L.8    Qiu, S.9    Lee, J.M.10
  • 145
    • 84943617416 scopus 로고    scopus 로고
    • Natural and therapy-induced immunosurveillance in breast cancer
    • 26444637
    • G.Kroemer, L.Senovilla, L.Galluzzi, F.Andre, L.Zitvogel. Natural and therapy-induced immunosurveillance in breast cancer. Nat Med 2015; 21:1128-38; PMID:26444637; http://dx.doi.org/10.1038/nm.3944
    • (2015) Nat Med , vol.21 , pp. 1128-1138
    • Kroemer, G.1    Senovilla, L.2    Galluzzi, L.3    Andre, F.4    Zitvogel, L.5
  • 146
    • 84917706141 scopus 로고    scopus 로고
    • ADAM10 and ADAM17: New players in trastuzumab tesistance
    • 25460503
    • M.J.Duffy, J.Crown, M.Mullooly. ADAM10 and ADAM17: New players in trastuzumab tesistance. Oncotarget 2014; 5:10963-4; PMID:25460503; http://dx.doi.org/10.18632/oncotarget.2794
    • (2014) Oncotarget , vol.5 , pp. 10963-10964
    • Duffy, M.J.1    Crown, J.2    Mullooly, M.3
  • 147
    • 84916897470 scopus 로고    scopus 로고
    • p53 status as effect modifier of the association between pre-treatment fasting glucose and breast cancer outcomes in non diabetic, HER2 positive patients treated with trastuzumab
    • 25071015
    • P.Vici, F.Sperati, M.Maugeri-Sacca, E.Melucci, A.Di Benedetto, L.Di Lauro, L.Pizzuti, D.Sergi, I.Terrenato, L.Esposito p53 status as effect modifier of the association between pre-treatment fasting glucose and breast cancer outcomes in non diabetic, HER2 positive patients treated with trastuzumab. Oncotarget 2014; 5:10382-92; PMID:25071015; http://dx.doi.org/10.18632/oncotarget.2060
    • (2014) Oncotarget , vol.5 , pp. 10382-10392
    • Vici, P.1    Sperati, F.2    Maugeri-Sacca, M.3    Melucci, E.4    Di Benedetto, A.5    Di Lauro, L.6    Pizzuti, L.7    Sergi, D.8    Terrenato, I.9    Esposito, L.10
  • 148
    • 84881552775 scopus 로고    scopus 로고
    • A novel bispecific antibody recruits T cells to eradicate tumors in the "immunologically privileged" central nervous system
    • 23734318
    • B.D.Choi, I.Pastan, D.D.Bigner, J.H.Sampson. A novel bispecific antibody recruits T cells to eradicate tumors in the "immunologically privileged" central nervous system. Oncoimmunology 2013; 2:e23639; PMID:23734318; http://dx.doi.org/10.4161/onci.23639
    • (2013) Oncoimmunology , vol.2 , pp. 23639
    • Choi, B.D.1    Pastan, I.2    Bigner, D.D.3    Sampson, J.H.4
  • 149
    • 84900844248 scopus 로고    scopus 로고
    • Biting back: BiTE antibodies as a promising therapy for acute myeloid leukemia
    • 24617311
    • R.B.Walter. Biting back: BiTE antibodies as a promising therapy for acute myeloid leukemia. Expert Rev Hematol 2014; 7:317-9; PMID:24617311; http://dx.doi.org/10.1586/17474086.2014.896190
    • (2014) Expert Rev Hematol , vol.7 , pp. 317-319
    • Walter, R.B.1
  • 150
    • 84906241263 scopus 로고    scopus 로고
    • A FcgammaRIII-engaging bispecific antibody expands the range of HER2-expressing breast tumors eligible to antibody therapy
    • 24979648
    • M.Turini, P.Chames, P.Bruhns, D.Baty, B.Kerfelec. A FcgammaRIII-engaging bispecific antibody expands the range of HER2-expressing breast tumors eligible to antibody therapy. Oncotarget 2014; 5:5304-19; PMID:24979648; http://dx.doi.org/10.18632/oncotarget.2093
    • (2014) Oncotarget , vol.5 , pp. 5304-5319
    • Turini, M.1    Chames, P.2    Bruhns, P.3    Baty, D.4    Kerfelec, B.5
  • 151
    • 51349104272 scopus 로고    scopus 로고
    • Telomerase as a universal tumor antigen for cancer vaccines
    • 18767939
    • G.L.Beatty, R.H.Vonderheide. Telomerase as a universal tumor antigen for cancer vaccines. Expert Rev Vaccines 2008; 7:881-7; PMID:18767939; http://dx.doi.org/10.1586/14760584.7.7.881
    • (2008) Expert Rev Vaccines , vol.7 , pp. 881-887
    • Beatty, G.L.1    Vonderheide, R.H.2
  • 152
    • 0033826798 scopus 로고    scopus 로고
    • Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells
    • 10973321
    • S.K.Nair, A.Heiser, D.Boczkowski, A.Majumdar, M.Naoe, J.S.Lebkowski, J.Vieweg, E.Gilboa. Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells. Nat Med 2000; 6:1011-7; PMID:10973321; http://dx.doi.org/10.1038/79519
    • (2000) Nat Med , vol.6 , pp. 1011-1017
    • Nair, S.K.1    Heiser, A.2    Boczkowski, D.3    Majumdar, A.4    Naoe, M.5    Lebkowski, J.S.6    Vieweg, J.7    Gilboa, E.8
  • 153
    • 84975810910 scopus 로고    scopus 로고
    • Dinutuximab approved for high-risk neuroblastoma
    • Dinutuximab approved for high-risk neuroblastoma. Cancer Discov 2015; 5:OF5; PMID:25851859; http://dx.doi.org/10.1158/2159-8290.CD-NB2015-044
    • (2015) Cancer Discov , vol.5 , pp. 5
  • 154
    • 84921345093 scopus 로고    scopus 로고
    • Antibodies to watch in 2015
    • 25484055
    • J.M.Reichert. Antibodies to watch in 2015. MAbs 2015; 7:1-8; PMID:25484055; http://dx.doi.org/10.4161/19420862.2015.988944
    • (2015) MAbs , vol.7 , pp. 1-8
    • Reichert, J.M.1
  • 155
    • 84939988507 scopus 로고    scopus 로고
    • Immune checkpoint modulation: rational design of combination strategies
    • 25583297
    • D.Zamarin, M.A.Postow. Immune checkpoint modulation: rational design of combination strategies. Pharmacol Ther 2015; 150:23-32; PMID:25583297; http://dx.doi.org/10.1016/j.pharmthera.2015.01.003
    • (2015) Pharmacol Ther , vol.150 , pp. 23-32
    • Zamarin, D.1    Postow, M.A.2
  • 156
    • 84920031403 scopus 로고    scopus 로고
    • EBV-driven LMP1 and IFN-gamma up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy
    • 25361008
    • W.Fang, J.Zhang, S.Hong, J.Zhan, N.Chen, T.Qin, Y.Tang, Y.Zhang, S.Kang, T.Zhou EBV-driven LMP1 and IFN-gamma up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy. Oncotarget 2014; 5:12189-202; PMID:25361008; http://dx.doi.org/10.18632/oncotarget.2608
    • (2014) Oncotarget , vol.5 , pp. 12189-12202
    • Fang, W.1    Zhang, J.2    Hong, S.3    Zhan, J.4    Chen, N.5    Qin, T.6    Tang, Y.7    Zhang, Y.8    Kang, S.9    Zhou, T.10
  • 157
    • 84908880944 scopus 로고    scopus 로고
    • Cell and molecular biology of epidermal growth factor receptor
    • 25376492
    • B.P.Ceresa, J.L.Peterson. Cell and molecular biology of epidermal growth factor receptor. Int Rev Cell Mol Biol 2014; 313:145-78; PMID:25376492; http://dx.doi.org/10.1016/B978-0-12-800177-6.00005-0
    • (2014) Int Rev Cell Mol Biol , vol.313 , pp. 145-178
    • Ceresa, B.P.1    Peterson, J.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.