-
1
-
-
42449151214
-
Functions of natural killer cells
-
Vivier, E., Tomasello, E., Baratin, M., Walzer, T. & Ugolini, S. Functions of natural killer cells. Nat. Immunol. 9, 503-510 (2008).
-
(2008)
Nat. Immunol.
, vol.9
, pp. 503-510
-
-
Vivier, E.1
Tomasello, E.2
Baratin, M.3
Walzer, T.4
Ugolini, S.5
-
2
-
-
84872977452
-
Innate lymphoid cells-A proposal for uniform nomenclature
-
Spits, H. et al. Innate lymphoid cells-a proposal for uniform nomenclature. Nat. Rev. Immunol. 13, 145-149 (2013).
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 145-149
-
-
Spits, H.1
-
3
-
-
36248966560
-
Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor
-
Walzer, T. et al. Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor. Nat. Immunol. 8, 1337-1344 (2007).
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1337-1344
-
-
Walzer, T.1
-
4
-
-
57849145994
-
Influence of the transcription factor RORt on the development of NKp46+ cell populations in gut and skin
-
Luci, C. et al. Influence of the transcription factor RORt on the development of NKp46+ cell populations in gut and skin. Nat. Immunol. 10, 75-82 (2009).
-
(2009)
Nat. Immunol.
, vol.10
, pp. 75-82
-
-
Luci, C.1
-
5
-
-
57849117363
-
RORt and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells
-
Sanos, S.L. et al. RORt and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells. Nat. Immunol. 10, 83-91 (2009).
-
(2009)
Nat. Immunol.
, vol.10
, pp. 83-91
-
-
Sanos, S.L.1
-
6
-
-
57449118239
-
Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense
-
Satoh-Takayama, N. et al. Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense. Immunity 29, 958-970 (2008).
-
(2008)
Immunity
, vol.29
, pp. 958-970
-
-
Satoh-Takayama, N.1
-
7
-
-
67049114093
-
Maturation of mouse NK cells is a 4-stage developmental program
-
Chiossone, L. et al. Maturation of mouse NK cells is a 4-stage developmental program. Blood 113, 5488-5496 (2009).
-
(2009)
Blood
, vol.113
, pp. 5488-5496
-
-
Chiossone, L.1
-
8
-
-
31144449386
-
CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacity
-
Hayakawa, Y. & Smyth, M.J. CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacity. J. Immunol. 176, 1517-1524 (2006).
-
(2006)
J. Immunol.
, vol.176
, pp. 1517-1524
-
-
Hayakawa, Y.1
Smyth, M.J.2
-
9
-
-
0037111585
-
In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells
-
Cooper, M.A. In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells. Blood 100, 3633-3638 (2002).
-
(2002)
Blood
, vol.100
, pp. 3633-3638
-
-
Cooper, M.A.1
-
10
-
-
0034610970
-
Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice
-
Kennedy, M.K. et al. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J. Exp. Med. 191, 771-780 (2000).
-
(2000)
J. Exp. Med.
, vol.191
, pp. 771-780
-
-
Kennedy, M.K.1
-
11
-
-
0032211699
-
IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
-
Lodolce, J.P. et al. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 9, 669-676 (1998).
-
(1998)
Immunity
, vol.9
, pp. 669-676
-
-
Lodolce, J.P.1
-
12
-
-
12444295407
-
Roles for common cytokine receptor -chain-dependent cytokines in the generation, differentiation, and maturation of NK cell precursors and peripheral NK cells in vivo
-
Vosshenrich, C.A.J. et al. Roles for common cytokine receptor -chain-dependent cytokines in the generation, differentiation, and maturation of NK cell precursors and peripheral NK cells in vivo. J. Immunol. 174, 1213-1221 (2005).
-
(2005)
J. Immunol.
, vol.174
, pp. 1213-1221
-
-
Vosshenrich, C.A.J.1
-
13
-
-
70449533145
-
Macrophage- and dendritic-cell-derived interleukin-15 receptor supports homeostasis of distinct CD8+ T cell subsets
-
Mortier, E. et al. Macrophage- and dendritic-cell-derived interleukin-15 receptor supports homeostasis of distinct CD8+ T cell subsets. Immunity 31, 811-822 (2009).
-
(2009)
Immunity
, vol.31
, pp. 811-822
-
-
Mortier, E.1
-
14
-
-
80051630276
-
Different NK cell developmental events require different levels of IL-15 trans-presentation
-
Lee, G.A. et al. Different NK cell developmental events require different levels of IL-15 trans-presentation. J. Immunol. 187, 1212-1221 (2011).
-
(2011)
J. Immunol.
, vol.187
, pp. 1212-1221
-
-
Lee, G.A.1
-
15
-
-
57349181367
-
In vivo expression of signaling proteins in reconstituted NK cells
-
Orr, S.J., Quigley, L. & Mcvicar, D.W. In vivo expression of signaling proteins in reconstituted NK cells. J. Immunol. Meth. 340, 158-163 (2009).
-
(2009)
J. Immunol. Meth.
, vol.340
, pp. 158-163
-
-
Orr, S.J.1
Quigley, L.2
McVicar, D.W.3
-
16
-
-
77956399493
-
Implications for gene therapy-limiting expression of IL-2R c delineate differences in signaling thresholds required for lymphocyte development and maintenance
-
Orr, S.J. et al. Implications for gene therapy-limiting expression of IL-2R c delineate differences in signaling thresholds required for lymphocyte development and maintenance. J. Immunol. 185, 1393-1403 (2010).
-
(2010)
J. Immunol.
, vol.185
, pp. 1393-1403
-
-
Orr, S.J.1
-
17
-
-
79551643771
-
A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development
-
Eckelhart, E. et al. A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development. Blood 117, 1565-1573 (2011).
-
(2011)
Blood
, vol.117
, pp. 1565-1573
-
-
Eckelhart, E.1
-
18
-
-
84876758617
-
Metabolic pathways in immune cell activation and quiescence
-
Pearce, E.L. & Pearce, E.J. Metabolic pathways in immune cell activation and quiescence. Immunity 38, 633-643 (2013).
-
(2013)
Immunity
, vol.38
, pp. 633-643
-
-
Pearce, E.L.1
Pearce, E.J.2
-
19
-
-
84878831880
-
Posttranscriptional control of T cell effector function by aerobic glycolysis
-
Chang, C.-H. et al. Posttranscriptional control of T cell effector function by aerobic glycolysis. Cell 153, 1239-1251 (2013).
-
(2013)
Cell
, vol.153
, pp. 1239-1251
-
-
Chang, C.-H.1
-
20
-
-
42449110816
-
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking
-
Sinclair, L.V. et al. Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking. Nat. Immunol. 9, 513-521 (2008).
-
(2008)
Nat. Immunol.
, vol.9
, pp. 513-521
-
-
Sinclair, L.V.1
-
21
-
-
84859778293
-
MTOR signaling in growth control and disease
-
Laplante, M. & Sabatini, D.M. mTOR signaling in growth control and disease. Cell 149, 274-293 (2012).
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
22
-
-
84055178474
-
Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks
-
Magnuson, B., Ekim, B. & Fingar, D.C. Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks. Biochem. J. 441, 1-21 (2011).
-
(2011)
Biochem. J.
, vol.441
, pp. 1-21
-
-
Magnuson, B.1
Ekim, B.2
Fingar, D.C.3
-
23
-
-
84866562625
-
Metabolic checkpoints in activated T cells
-
Wang, R. & Green, D.R. Metabolic checkpoints in activated T cells. Nat. Immunol. 13, 907-915 (2012).
-
(2012)
Nat. Immunol.
, vol.13
, pp. 907-915
-
-
Wang, R.1
Green, D.R.2
-
24
-
-
84867649112
-
Differential responses of immune cells to type i interferon contribute to host resistance to viral infection
-
Baranek, T. et al. Differential responses of immune cells to type I interferon contribute to host resistance to viral infection. Cell Host Microbe 12, 571-584 (2012).
-
(2012)
Cell Host Microbe
, vol.12
, pp. 571-584
-
-
Baranek, T.1
-
25
-
-
34250200713
-
Acquisition of murine NK cell cytotoxicity requires the translation of a pre-existing pool of granzyme B and perforin mRNAs
-
Fehniger, T.A. et al. Acquisition of murine NK cell cytotoxicity requires the translation of a pre-existing pool of granzyme B and perforin mRNAs. Immunity 26, 798-811 (2007).
-
(2007)
Immunity
, vol.26
, pp. 798-811
-
-
Fehniger, T.A.1
-
26
-
-
74049088121
-
Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy
-
Risson, V. et al. Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy. J. Cell Biol. 187, 859-874 (2009).
-
(2009)
J. Cell Biol.
, vol.187
, pp. 859-874
-
-
Risson, V.1
-
27
-
-
81055145276
-
Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor
-
Narni-Mancinelli, E. et al. Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor. Proc. Natl. Acad. Sci. USA 108, 18324-18329 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 18324-18329
-
-
Narni-Mancinelli, E.1
-
28
-
-
84862777436
-
The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation
-
Gordon, S.M. et al. The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation. Immunity 36, 55-67 (2012).
-
(2012)
Immunity
, vol.36
, pp. 55-67
-
-
Gordon, S.M.1
-
29
-
-
0036079077
-
In vivo developmental stages in murine natural killer cell maturation
-
Kim, S. et al. In vivo developmental stages in murine natural killer cell maturation. Nat. Immunol. 3, 523-528 (2002).
-
(2002)
Nat. Immunol.
, vol.3
, pp. 523-528
-
-
Kim, S.1
-
30
-
-
0037108345
-
Coordinated and distinct roles for IFN-, IL-12, and IL-15 regulation of NK cell responses to viral infection
-
Nguyen, K.B. et al. Coordinated and distinct roles for IFN-, IL-12, and IL-15 regulation of NK cell responses to viral infection. J. Immunol. 169, 4279-4287 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 4279-4287
-
-
Nguyen, K.B.1
-
31
-
-
0034774942
-
Specific and nonspecific NK cell activation during virus infection
-
Dokun, A.O. et al. Specific and nonspecific NK cell activation during virus infection. Nat. Immunol. 2, 951-956 (2001).
-
(2001)
Nat. Immunol.
, vol.2
, pp. 951-956
-
-
Dokun, A.O.1
-
32
-
-
70349231090
-
Cutting Edge: IL-15-independent NK cell response to mouse cytomegalovirus infection
-
Sun, J.C., Ma, A. & Lanier, L.L. Cutting Edge: IL-15-independent NK cell response to mouse cytomegalovirus infection. J. Immunol. 183, 2911-2914 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 2911-2914
-
-
Sun, J.C.1
Ma, A.2
Lanier, L.L.3
-
33
-
-
84872527628
-
MTOR is a key modulator of ageing and age-related disease
-
Johnson, S.C., Rabinovitch, P.S. & Kaeberlein, M. mTOR is a key modulator of ageing and age-related disease. Nature 493, 338-345 (2013).
-
(2013)
Nature
, vol.493
, pp. 338-345
-
-
Johnson, S.C.1
Rabinovitch, P.S.2
Kaeberlein, M.3
-
34
-
-
61349141302
-
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2
-
Feldman, M.E. et al. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol. 7, e38 (2009).
-
(2009)
PLoS Biol.
, vol.7
-
-
Feldman, M.E.1
-
35
-
-
67650312583
-
Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)
-
García-Martínez, J.M. et al. Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR). Biochem. J. 421, 29-42 (2009).
-
(2009)
Biochem. J.
, vol.421
, pp. 29-42
-
-
García-Martínez, J.M.1
-
36
-
-
66949173728
-
The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment
-
Delgoffe, G.M. et al. The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity 30, 832-844 (2009).
-
(2009)
Immunity
, vol.30
, pp. 832-844
-
-
Delgoffe, G.M.1
-
37
-
-
0036069699
-
The CD28 signaling pathway regulates glucose metabolism
-
Frauwirth, K.A. et al. The CD28 signaling pathway regulates glucose metabolism. Immunity 16, 769-777 (2002).
-
(2002)
Immunity
, vol.16
, pp. 769-777
-
-
Frauwirth, K.A.1
-
38
-
-
77953897189
-
Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways
-
Lee, K. et al. Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways. Immunity 32, 743-753 (2010).
-
(2010)
Immunity
, vol.32
, pp. 743-753
-
-
Lee, K.1
-
40
-
-
73349119966
-
MAPK, Phosphatidylinositol 3-kinase, and mammalian target of rapamycin pathways converge at the level of ribosomal protein S6 phosphorylation to control metabolic signaling in CD8 T cells
-
Salmond, R.J., Emery, J., Okkenhaug, K. & Zamoyska, R. MAPK, Phosphatidylinositol 3-kinase, and mammalian target of rapamycin pathways converge at the level of ribosomal protein S6 phosphorylation to control metabolic signaling in CD8 T cells. J. Immunol. 183, 7388-7397 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 7388-7397
-
-
Salmond, R.J.1
Emery, J.2
Okkenhaug, K.3
Zamoyska, R.4
-
41
-
-
33748471980
-
MSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s
-
Frias, M.A. et al. mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s. Curr. Biol. 16, 1865-1870 (2006).
-
(2006)
Curr. Biol.
, vol.16
, pp. 1865-1870
-
-
Frias, M.A.1
-
42
-
-
84871861969
-
PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells
-
Finlay, D.K. et al. PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells. J. Exp. Med. 209, 2441-2453 (2012).
-
(2012)
J. Exp. Med.
, vol.209
, pp. 2441-2453
-
-
Finlay, D.K.1
-
43
-
-
34548039233
-
P110gamma and p110 phosphoinositide 3-kinase signaling pathways synergize to control development and functions of murine NK cells
-
Tassi, I. et al. p110gamma and p110 phosphoinositide 3-kinase signaling pathways synergize to control development and functions of murine NK cells. Immunity 27, 214-227 (2007).
-
(2007)
Immunity
, vol.27
, pp. 214-227
-
-
Tassi, I.1
-
44
-
-
53349143413
-
The p110 of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation
-
Guo, H., Samarakoon, A., Vanhaesebroeck, B. & Malarkannan, S. The p110 of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation. J. Exp. Med. 205, 2419-2435 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2419-2435
-
-
Guo, H.1
Samarakoon, A.2
Vanhaesebroeck, B.3
Malarkannan, S.4
-
45
-
-
36148992966
-
The p110 catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion
-
Kim, N. et al. The p110 catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion. Blood 110, 3202-3208 (2007).
-
(2007)
Blood
, vol.110
, pp. 3202-3208
-
-
Kim, N.1
-
46
-
-
78049268109
-
Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival
-
Hand, T.W. et al. Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival. Proc. Natl. Acad. Sci. USA 107, 16601-16606 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 16601-16606
-
-
Hand, T.W.1
-
47
-
-
84872189584
-
NK cell maturation and function in C57BL/6 mice are altered by caloric restriction
-
Clinthorne, J.F., Beli, E., Duriancik, D.M. & Gardner, E.M. NK cell maturation and function in C57BL/6 mice are altered by caloric restriction. J. Immunol. 190, 712-722 (2013).
-
(2013)
J. Immunol.
, vol.190
, pp. 712-722
-
-
Clinthorne, J.F.1
Beli, E.2
Duriancik, D.M.3
Gardner, E.M.4
-
48
-
-
84860527756
-
A unifying model for mTORC1-mediated regulation of mRNA translation
-
Thoreen, C.C. et al. A unifying model for mTORC1-mediated regulation of mRNA translation. Nature 485, 109-113 (2012).
-
(2012)
Nature
, vol.485
, pp. 109-113
-
-
Thoreen, C.C.1
-
49
-
-
7944235758
-
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
-
Jacinto, E. et al. Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat. Cell Biol. 6, 1122-1128 (2004).
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 1122-1128
-
-
Jacinto, E.1
-
50
-
-
84892178328
-
Regulation of mouse NK cell development and function by cytokines
-
Marçais, A. et al. Regulation of mouse NK cell development and function by cytokines. Front. Immunol. 4, 450 (2013).
-
(2013)
Front. Immunol.
, vol.4
, pp. 450
-
-
Marçais, A.1
|