-
1
-
-
84856152266
-
Targeting MET in cancer: Rationale and progress
-
Gherardi, E., Birchmeier, W., Birchmeier, C. & Vande Woude, G. Targeting MET in cancer: rationale and progress. Nature Rev. Cancer 12, 89-103 (2012).
-
(2012)
Nature Rev. Cancer
, vol.12
, pp. 89-103
-
-
Gherardi, E.1
Birchmeier, W.2
Birchmeier, C.3
Vande Woude, G.4
-
2
-
-
77449088691
-
Only a subset of Met-activated pathways are required to sustain oncogene addiction
-
Bertotti, A. et al. Only a subset of Met-activated pathways are required to sustain oncogene addiction. Sci. Signal. 2, ra80 (2009).
-
(2009)
Sci. Signal.
, vol.2
, pp. ra80
-
-
Bertotti, A.1
-
3
-
-
84555190809
-
METamplification identifies asmall and aggressive subgroup of esophagogastric adenocarcinomawith evidence of responsiveness to crizotinib
-
Lennerz, J. K. et al.METamplification identifies asmall and aggressive subgroup of esophagogastric adenocarcinomawith evidence of responsiveness to crizotinib. J. Clin. Oncol. 29, 4803-4810 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 4803-4810
-
-
Lennerz, J.K.1
-
4
-
-
84872548337
-
Phase II andbiomarker study of the dualMET/VEGFR2inhibitor foretinib in patientswith papillary renal cell carcinoma
-
Choueiri, T.K. et al.Phase II andbiomarker study of the dualMET/VEGFR2inhibitor foretinib in patientswith papillary renal cell carcinoma. J. Clin. Oncol. 31, 181-186 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
, pp. 181-186
-
-
Choueiri, T.K.1
-
5
-
-
44449151030
-
Drug development of MET inhibitors: Targeting oncogene addiction and expedience
-
Comoglio, P.M., Giordano, S. & Trusolino, L. Drug development of MET inhibitors: targeting oncogene addiction and expedience. Nature Rev. Drug Discov. 7, 504-516 (2008).
-
(2008)
Nature Rev. Drug Discov.
, vol.7
, pp. 504-516
-
-
Comoglio, P.M.1
Giordano, S.2
Trusolino, L.3
-
6
-
-
0026722243
-
Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cellmotility and growth
-
Bussolino, F. et al. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cellmotility and growth. J. Cell Biol. 119, 629-641 (1992).
-
(1992)
J. Cell Biol.
, vol.119
, pp. 629-641
-
-
Bussolino, F.1
-
7
-
-
34248529664
-
Hepatocyte growth factor and c-Met expression in pericytes: Implications for atherosclerotic plaquedevelopment
-
Liu, Y. et al. Hepatocyte growth factor and c-Met expression in pericytes: implications for atherosclerotic plaquedevelopment. J. Pathol.212,12-19(2007).
-
(2007)
J. Pathol.
, vol.212
, pp. 12-19
-
-
Liu, Y.1
-
8
-
-
0029802366
-
Induction of met proto-oncogene (hepatocyte growth factor receptor) expression during human monocytemacrophage differentiation
-
Chen, Q., DeFrances, M. C. & Zarnegar, R. Induction of met proto-oncogene (hepatocyte growth factor receptor) expression during human monocytemacrophage differentiation. Cell Growth Differ. 7, 821-832 (1996).
-
(1996)
Cell Growth Differ.
, vol.7
, pp. 821-832
-
-
Chen, Q.1
Defrances, M.C.2
Zarnegar, R.3
-
9
-
-
84864803976
-
The HGF receptor/Met tyrosine kinase is a key regulator of dendritic cell migration in skin immunity
-
Baek, J. H., Birchmeier, C., Zenke, M. & Hieronymus, T. The HGF receptor/Met tyrosine kinase is a key regulator of dendritic cell migration in skin immunity. J. Immunol. 189, 1699-1707 (2012).
-
(2012)
J. Immunol.
, vol.189
, pp. 1699-1707
-
-
Baek, J.H.1
Birchmeier, C.2
Zenke, M.3
Hieronymus, T.4
-
10
-
-
0028365273
-
Hepatocyte growth factor and macrophage inflammatory protein 1b: Structurally distinct cytokines that induce rapid cytoskeletal changes and subset-preferential migration in T cells
-
Adams, D. H. et al. Hepatocyte growth factor and macrophage inflammatory protein 1b: structurally distinct cytokines that induce rapid cytoskeletal changes and subset-preferential migration in T cells. Proc. Natl Acad. Sci. USA 91, 7144-7148 (1994).
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 7144-7148
-
-
Adams, D.H.1
-
11
-
-
78751565017
-
Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling
-
Tesio, M. et al. Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling. Blood 117, 419-428 (2011).
-
(2011)
Blood
, vol.117
, pp. 419-428
-
-
Tesio, M.1
-
12
-
-
80455122752
-
Macrophage skewing byPhd2haplodeficiency prevents ischaemia by inducing arteriogenesis
-
Takeda, Y. et al.Macrophage skewing byPhd2haplodeficiency prevents ischaemia by inducing arteriogenesis. Nature 479, 122-126 (2011).
-
(2011)
Nature
, vol.479
, pp. 122-126
-
-
Takeda, Y.1
-
13
-
-
80054728763
-
Deletion of Syk in neutrophils prevents immune complex arthritis
-
Elliott, E. R. et al. Deletion of Syk in neutrophils prevents immune complex arthritis. J. Immunol. 187, 4319-4330 (2011).
-
(2011)
J. Immunol.
, vol.187
, pp. 4319-4330
-
-
Elliott, E.R.1
-
14
-
-
67449099888
-
SystemicNK4 gene therapy inhibits tumor growth andmetastasis of melanoma and lung carcinoma in syngeneic mouse tumor models
-
Kishi, Y. et al. SystemicNK4 gene therapy inhibits tumor growth andmetastasis of melanoma and lung carcinoma in syngeneic mouse tumor models. Cancer Sci. 100, 1351-1358 (2009).
-
(2009)
Cancer Sci.
, vol.100
, pp. 1351-1358
-
-
Kishi, Y.1
-
15
-
-
0037478437
-
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
-
Pennacchietti, S. et al. Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. Cancer Cell 3, 347-361 (2003).
-
(2003)
Cancer Cell
, vol.3
, pp. 347-361
-
-
Pennacchietti, S.1
-
16
-
-
0028318915
-
Modulation of c-MET proto-oncogene (HGF receptor) mRNA abundance by cytokines and hormones: Evidence for rapid decay of the 8kb c-MET transcript
-
Moghul, A. et al. Modulation of c-MET proto-oncogene (HGF receptor) mRNA abundance by cytokines and hormones: evidence for rapid decay of the 8kb c-MET transcript. Oncogene 9, 2045-2052 (1994).
-
(1994)
Oncogene
, vol.9
, pp. 2045-2052
-
-
Moghul, A.1
-
17
-
-
68049106050
-
The Met protooncogene is a transcriptional target of NFkB: Implications for cell survival
-
Dai, J. Y., DeFrances, M. C., Zou, C., Johnson, C. J. & Zarnegar, R. The Met protooncogene is a transcriptional target of NFkB: implications for cell survival. J. Cell. Biochem. 107, 1222-1236 (2009).
-
(2009)
J. Cell. Biochem.
, vol.107
, pp. 1222-1236
-
-
Dai, J.Y.1
Defrances, M.C.2
Zou, C.3
Johnson, C.J.4
Zarnegar, R.5
-
18
-
-
59849096397
-
IFATS collection: Fibroblast growth factor-2-induced hepatocyte growth factor secretion by adipose-derived stromal cells inhibits postinjury fibrogenesis through a c-Jun N-terminal kinase-dependent mechanism
-
Suga, H. et al. IFATS collection: fibroblast growth factor-2-induced hepatocyte growth factor secretion by adipose-derived stromal cells inhibits postinjury fibrogenesis through a c-Jun N-terminal kinase-dependent mechanism. Stem Cells 27, 238-249 (2009).
-
(2009)
Stem Cells
, vol.27
, pp. 238-249
-
-
Suga, H.1
-
19
-
-
84860484044
-
Tumor-associated neutrophils: Friend or foe?
-
Fridlender, Z. G. & Albelda, S. M. Tumor-associated neutrophils: friend or foe? Carcinogenesis 33, 949-955 (2012).
-
(2012)
Carcinogenesis
, vol.33
, pp. 949-955
-
-
Fridlender, Z.G.1
Albelda, S.M.2
-
20
-
-
84905373271
-
MET inhibitors start on road to recovery
-
Garber, K. MET inhibitors start on road to recovery. Nature Rev. Drug Discov. 13, 563-565 (2014).
-
(2014)
Nature Rev. Drug Discov.
, vol.13
, pp. 563-565
-
-
Garber, K.1
-
21
-
-
77955739070
-
Neutrophil function in inflammation and inflammatory diseases
-
Wright, H. L., Moots, R. J., Bucknall, R. C. & Edwards, S. W. Neutrophil function in inflammation and inflammatory diseases. Rheumatology 49, 1618-1631 (2010).
-
(2010)
Rheumatology
, vol.49
, pp. 1618-1631
-
-
Wright, H.L.1
Moots, R.J.2
Bucknall, R.C.3
Edwards, S.W.4
-
22
-
-
7044269527
-
JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells
-
Passegué, E., Wagner, E. F. & Weissman, I. L. JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells. Cell 119, 431-443 (2004).
-
(2004)
Cell
, vol.119
, pp. 431-443
-
-
Passegué, E.1
Wagner, E.F.2
Weissman, I.L.3
-
23
-
-
70350425052
-
Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection
-
Van Ziffle, J. A. & Lowell, C. A. Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection. Blood 114, 4871-4882 (2009).
-
(2009)
Blood
, vol.114
, pp. 4871-4882
-
-
Van Ziffle, J.A.1
Lowell, C.A.2
-
24
-
-
84875532599
-
Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice
-
Abram, C. L., Roberge, G. L., Pao, L. I., Neel, B. G. & Lowell, C. A. Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice. Immunity 38, 489-501 (2013).
-
(2013)
Immunity
, vol.38
, pp. 489-501
-
-
Abram, C.L.1
Roberge, G.L.2
Pao, L.I.3
Neel, B.G.4
Lowell, C.A.5
-
25
-
-
84886859795
-
Neutrophils mediate antibody-induced antitumor effects in mice
-
Albanesi, M. et al. Neutrophils mediate antibody-induced antitumor effects in mice. Blood 122, 3160-3164 (2013).
-
(2013)
Blood
, vol.122
, pp. 3160-3164
-
-
Albanesi, M.1
-
26
-
-
0023944868
-
Cloning and expression of two human genes encoding calcium-binding proteins that are regulated during myeloid differentiation
-
Lagasse, E. & Clerc, R. G. Cloning and expression of two human genes encoding calcium-binding proteins that are regulated during myeloid differentiation. Mol. Cell. Biol. 8, 2402-2410 (1988).
-
(1988)
Mol. Cell. Biol.
, vol.8
, pp. 2402-2410
-
-
Lagasse, E.1
Clerc, R.G.2
-
27
-
-
84878707647
-
PHD2regulates arteriogenicmacrophages through TIE2signalling
-
Hamm, A. et al.PHD2regulates arteriogenicmacrophages through TIE2signalling. EMBO Mol. Med. 5, 843-857 (2013).
-
(2013)
EMBO Mol. Med.
, vol.5
, pp. 843-857
-
-
Hamm, A.1
-
28
-
-
34548162712
-
An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression
-
Neufert, C., Becker, C. & Neurath, M. F. An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression. Nature Protocols 2, 1998-2004 (2007).
-
(2007)
Nature Protocols
, vol.2
, pp. 1998-2004
-
-
Neufert, C.1
Becker, C.2
Neurath, M.F.3
-
29
-
-
0019382757
-
The "Swiss roll": A simple technique for histological studies of the rodent intestine
-
Moolenbeek, C. & Ruitenberg, E. J. The "Swiss roll": a simple technique for histological studies of the rodent intestine. Lab. Anim. 15, 57-59 (1981).
-
(1981)
Lab. Anim.
, vol.15
, pp. 57-59
-
-
Moolenbeek, C.1
Ruitenberg, E.J.2
-
30
-
-
84897846435
-
Hydrodynamic transfection for generation of novel mouse models for liver cancer research
-
Chen, X. & Calvisi, D. F. Hydrodynamic transfection for generation of novel mouse models for liver cancer research. Am. J. Pathol. 184, 912-923 (2014).
-
(2014)
Am. J. Pathol.
, vol.184
, pp. 912-923
-
-
Chen, X.1
Calvisi, D.F.2
-
31
-
-
84857228824
-
Significant clinical, neuropathological and behavioural recovery from acute spinal cord trauma by transplantation of a well-defined somatic stem cell from human umbilical cord blood
-
Schira, J. et al. Significant clinical, neuropathological and behavioural recovery from acute spinal cord trauma by transplantation of a well-defined somatic stem cell from human umbilical cord blood. Brain 135, 431-446 (2012).
-
(2012)
Brain
, vol.135
, pp. 431-446
-
-
Schira, J.1
-
32
-
-
0037423948
-
HIF-1a is essential for myeloid cell-mediated inflammation
-
Cramer, T. et al. HIF-1a is essential for myeloid cell-mediated inflammation. Cell 112, 645-657 (2003).
-
(2003)
Cell
, vol.112
, pp. 645-657
-
-
Cramer, T.1
-
33
-
-
0034891987
-
A novel method for isolation of neutrophils from murine blood using negative immunomagnetic separation
-
Cotter, M. J., Norman, K. E., Hellewell, P. G. & Ridger, V. C. A novel method for isolation of neutrophils from murine blood using negative immunomagnetic separation. Am. J. Pathol. 159, 473-481 (2001).
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 473-481
-
-
Cotter, M.J.1
Norman, K.E.2
Hellewell, P.G.3
Ridger, V.C.4
-
34
-
-
0021908138
-
Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide
-
Haslett, C., Guthrie, L. A., Kopaniak, M. M., Johnston, R. B. Jr & Henson, P. M. Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide. Am. J. Pathol. 119, 101-110 (1985).
-
(1985)
Am. J. Pathol.
, vol.119
, pp. 101-110
-
-
Haslett, C.1
Guthrie, L.A.2
Kopaniak, M.M.3
Johnston, R.B.4
Henson, P.M.5
-
35
-
-
50349097617
-
Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: Implications for antiangiogenic drugs as chemosensitizing agents
-
Shaked, Y. et al. Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents. Cancer Cell 14, 263-273 (2008).
-
(2008)
Cancer Cell
, vol.14
, pp. 263-273
-
-
Shaked, Y.1
|