An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic mice

Human Molecular Genetics

Volumn 24, Issue 25, 2015, Pages 7241-7254

  Walker, Adam K ^a   Tripathy, Kalyan ^a   Restrepo, Clark R ^a   Ge, Guanghui ^a   Xu, Yan ^a   Kwong, Linda K ^a   Trojanowski, John Q ^a   Lee, Virginia M Y ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P62; TAR DNA BINDING PROTEIN; UBIQUITIN; DNA BINDING PROTEIN; TDP-43 PROTEIN, HUMAN;

ADULT; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; CARBOXY TERMINAL SEQUENCE; CELL INCLUSION; CELL LOSS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DENDRITE; DENTATE GYRUS; FEMALE; FRONTAL CORTEX; FRONTOTEMPORAL DEMENTIA; HIPPOCAMPAL CA1 REGION; HUMAN; HUMAN TISSUE; MALE; MITOCHONDRION; MOUSE; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; STRATUM LACUNOSUM MOLECULARE; TDP 43 PROTEINOPATHY; TRANSGENIC MOUSE; ANIMAL; COMPLICATION; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; METABOLISM; NEURODEGENERATIVE DISEASES; PATHOLOGY;

ANIMALS; DNA-BINDING PROTEINS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; FRONTOTEMPORAL DEMENTIA; FRONTOTEMPORAL LOBAR DEGENERATION; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, TRANSGENIC; NEURODEGENERATIVE DISEASES;

EID: 84959231089     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv424     Document Type: Article

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