A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement

Brain

Volumn 137, Issue 8, 2014, Pages 2329-2345

  Bannwarth, Sylvie ^a,b   Ait El Mkadem, Samira ^a,b   Chaussenot, Annabelle ^a,b   Genin, Emmanuelle C ^a   Lacas Gervais, Sandra ^c   Fragaki, Konstantina ^a,b   Berg Alonso, Laetitia ^a   Kageyama, Yusuke ^d   Serre, Valérie ^e   Moore, David G ^f   Verschueren, Annie ^g   Rouzier, Cécile ^a,b   Le Ber, Isabelle ^h,i   Augé, Gaëlle ^a,b   Cochaud, Charlotte ^b   Lespinasse, Françoise ^a   N'guyen, Karine ^g   De Septenville, Anne ^h   Brice, Alexis ^h   Yu Wai Man, Patrick ^f   Sesaki, Hiromi ^d   Pouget, Jean ^g   Paquis Flucklinger, Véronique ^a,b   more..

^a UNIVERSITY OF NICE SOPHIA ANTIPOLIS   (France)

^b UNIVERSITY HOSPITAL OF NICE   (France)

^c UNIVERSITÉ CÔTE D'AZUR   (France)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e CNRS   (France)

^f NEWCASTLE UNIVERSITY   (United Kingdom)

^g TIMONE HOSPITAL   (France)

^h INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE   (France)

ⁱ PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

CHCHD10; FTD ALS; mitochondrial disorder; mitochondrial DNA instability

Indexed keywords

CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CEREBELLAR ATAXIA; CHCHD10 GENE; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DISORIENTATION; EXOME; FEMALE; FIBROBLAST; FRONTOTEMPORAL DEMENTIA; GENE; GENE FREQUENCY; GENE OVEREXPRESSION; GENE SEQUENCE; HELA CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MIDDLE AGED; MISSENSE MUTATION; MITOCHONDRIAL DNA DISORDER; MUSCLE BIOPSY; MYOPATHY; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; RESPIRATORY CHAIN; SKELETAL MUSCLE;

CHCHD10; FTD-ALS; MITOCHONDRIAL DISORDER; MITOCHONDRIAL DNA INSTABILITY;

AGE OF ONSET; AGED; ALLELES; AMYOTROPHIC LATERAL SCLEROSIS; DNA, MITOCHONDRIAL; EXOME; FEMALE; FRONTOTEMPORAL DEMENTIA; HELA CELLS; HUMANS; MALE; MIDDLE AGED; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MITOCHONDRIAL PROTEINS; MUTATION, MISSENSE; PEDIGREE; PHENOTYPE;

EID: 84905041572     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awu138     Document Type: Article

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