-
1
-
-
48949088445
-
Frontotemporal dementia and related disorders: deciphering the enigma
-
Josephs, K. A., Frontotemporal dementia and related disorders: deciphering the enigma. Ann. Neurol. 2008, 64, 4-14.
-
(2008)
Ann. Neurol.
, vol.64
, pp. 4-14
-
-
Josephs, K.A.1
-
2
-
-
33744781515
-
clinicopathological correlations
-
Frontotemporal dementia.
-
Forman, M. S., Farmer, J., Johnson, J. K., Clark, C. M. et al., Frontotemporal dementia: clinicopathological correlations. Ann. Neurol. 2006, 59, 952-962.
-
(2006)
Ann. Neurol.
, vol.59
, pp. 952-962
-
-
Forman, M.S.1
Farmer, J.2
Johnson, J.K.3
Clark, C.M.4
-
3
-
-
77956850818
-
TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
-
Mackenzie, I. R., Rademakers, R., Neumann, M., TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia. Lancet Neurol. 2010, 9, 995-1007.
-
(2010)
Lancet Neurol.
, vol.9
, pp. 995-1007
-
-
Mackenzie, I.R.1
Rademakers, R.2
Neumann, M.3
-
4
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann, M., Sampathu, D. M., Kwong, L. K., Truax, A. C. et al., Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 2006, 314, 130-133.
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
-
5
-
-
77953890823
-
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
-
Lagier-Tourenne, C., Polymenidou, M., Cleveland, D. W., TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration. Hum. Mol. Genet. 2010, 19, R46-R64.
-
(2010)
Hum. Mol. Genet.
, vol.19
-
-
Lagier-Tourenne, C.1
Polymenidou, M.2
Cleveland, D.W.3
-
6
-
-
46749138739
-
Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Igaz, L. M., Kwong, L. K., Xu, Y., Truax, A. C. et al., Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Am. J. Pathol. 2008, 173, 182-194.
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 182-194
-
-
Igaz, L.M.1
Kwong, L.K.2
Xu, Y.3
Truax, A.C.4
-
7
-
-
0025899041
-
Amyloid deposition as the central event in the aetiology of Alzheimer's disease
-
Hardy, J., Allsop, D., Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol. Sci. 1991, 12, 383-388.
-
(1991)
Trends Pharmacol. Sci.
, vol.12
, pp. 383-388
-
-
Hardy, J.1
Allsop, D.2
-
8
-
-
13844320376
-
Aggregation promoting C-terminal truncation of α synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations
-
Li, W., West, N., Colla, E., Pletnikova, O. et al., Aggregation promoting C-terminal truncation of α synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations. Proc. Natl. Acad. Sci. USA 2005, 102, 2162-2167.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 2162-2167
-
-
Li, W.1
West, N.2
Colla, E.3
Pletnikova, O.4
-
9
-
-
0242361780
-
Role of proteolysis in polyglutamine disorders
-
Tarlac, V., Storey, E., Role of proteolysis in polyglutamine disorders. J. Neurosci. Res. 2003, 74, 406-416.
-
(2003)
J. Neurosci. Res.
, vol.74
, pp. 406-416
-
-
Tarlac, V.1
Storey, E.2
-
10
-
-
34547203592
-
Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model
-
Wang, Y. P., Biernat, J., Pickhardt, M., Mandelkow, E. et al., Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model. Proc. Natl. Acad. Sci. 2007, 104, 10252-10257.
-
(2007)
Proc. Natl. Acad. Sci.
, vol.104
, pp. 10252-10257
-
-
Wang, Y.P.1
Biernat, J.2
Pickhardt, M.3
Mandelkow, E.4
-
11
-
-
67649797399
-
Expression of TDP-43 C-terminal fragments in vitro recapitulates pathological features of TDP-43 proteinopathies
-
Igaz, L. M., Kwong, L. K., Chen-Plotkin, A., Winton, M. J. et al., Expression of TDP-43 C-terminal fragments in vitro recapitulates pathological features of TDP-43 proteinopathies. J. Biol. Chem. 2009, 284, 8516-8524.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 8516-8524
-
-
Igaz, L.M.1
Kwong, L.K.2
Chen-Plotkin, A.3
Winton, M.J.4
-
12
-
-
67650113333
-
Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43
-
Nonaka, T., Kametani, F., Arai, T., Akiyama, H., Hasegawa, M., Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43. Hum. Mol. Gen. 2009, 18, 3353-3364.
-
(2009)
Hum. Mol. Gen.
, vol.18
, pp. 3353-3364
-
-
Nonaka, T.1
Kametani, F.2
Arai, T.3
Akiyama, H.4
Hasegawa, M.5
-
13
-
-
34848921202
-
Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43
-
Zhang, Y. J., Xu, Y. F., Dickey, C. A., Buratti, E. et al., Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43. J. Neurosci. 2007, 27, 10530-10534.
-
(2007)
J. Neurosci.
, vol.27
, pp. 10530-10534
-
-
Zhang, Y.J.1
Xu, Y.F.2
Dickey, C.A.3
Buratti, E.4
-
14
-
-
66149114101
-
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
-
Zhang, Y.-J., Xu, Y.-F., Cook, C., Gendron, T. F. et al., Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity. Proc. Natl. Acad. Sci. 2009, 106, 7607-7612.
-
(2009)
Proc. Natl. Acad. Sci.
, vol.106
, pp. 7607-7612
-
-
Zhang, Y.-J.1
Xu, Y.-F.2
Cook, C.3
Gendron, T.F.4
-
15
-
-
67650432367
-
Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin
-
Dormann, D., Capell, A., Carlson, A. M., Shankaran, S. S. et al., Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin. J. Neurochem. 2009, 110, 1082-1094.
-
(2009)
J. Neurochem.
, vol.110
, pp. 1082-1094
-
-
Dormann, D.1
Capell, A.2
Carlson, A.M.3
Shankaran, S.S.4
-
16
-
-
34547663747
-
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions
-
Cairns, N. J., Neumann, M., Bigio, E. H., Holm, I. E. et al., TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. Am. J. Pathol. 2007, 171, 227-240.
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 227-240
-
-
Cairns, N.J.1
Neumann, M.2
Bigio, E.H.3
Holm, I.E.4
-
17
-
-
34249946466
-
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations
-
Mackenzie, I. R., Bigio, E. H., Ince, P. G., Geser, F. et al., Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Ann. Neurol. 2007, 61, 427-434.
-
(2007)
Ann. Neurol.
, vol.61
, pp. 427-434
-
-
Mackenzie, I.R.1
Bigio, E.H.2
Ince, P.G.3
Geser, F.4
-
18
-
-
34247123666
-
TDP-43-positive white matter pathology in frontotemporal lobar degeneration with ubiquitin-positive inclusions
-
Neumann, M., Kwong, L. K., Truax, A. C., Vanmassenhove, B. et al., TDP-43-positive white matter pathology in frontotemporal lobar degeneration with ubiquitin-positive inclusions. J. Neuropathol. Exp. Neurol. 2007, 66, 177-183.
-
(2007)
J. Neuropathol. Exp. Neurol.
, vol.66
, pp. 177-183
-
-
Neumann, M.1
Kwong, L.K.2
Truax, A.C.3
Vanmassenhove, B.4
-
19
-
-
35448970651
-
The molecular genetics and neuropathology of frontotemporal lobar degeneration: recent developments
-
Mackenzie, I. R., Rademakers, R., The molecular genetics and neuropathology of frontotemporal lobar degeneration: recent developments. Neurogenetics 2007, 8, 237-248.
-
(2007)
Neurogenetics
, vol.8
, pp. 237-248
-
-
Mackenzie, I.R.1
Rademakers, R.2
-
20
-
-
34447096691
-
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration
-
Cairns, N., Bigio, E., Mackenzie, I., Neumann, M. et al., Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathol. 2007, 114, 5-22.
-
(2007)
Acta Neuropathol.
, vol.114
, pp. 5-22
-
-
Cairns, N.1
Bigio, E.2
Mackenzie, I.3
Neumann, M.4
-
21
-
-
57049105123
-
Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations
-
Mackenzie, I., Neumann, M., Bigio, E., Cairns, N. et al., Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations. Acta Neuropathol. 2009, 117, 15-18.
-
(2009)
Acta Neuropathol.
, vol.117
, pp. 15-18
-
-
Mackenzie, I.1
Neumann, M.2
Bigio, E.3
Cairns, N.4
-
22
-
-
0025908356
-
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
-
Mirra, S. S., Heyman, A., McKeel, D., Sumi, S. M. et al., The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 1991, 41, 479-486.
-
(1991)
Neurology
, vol.41
, pp. 479-486
-
-
Mirra, S.S.1
Heyman, A.2
McKeel, D.3
Sumi, S.M.4
-
23
-
-
0030681215
-
Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease
-
Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease. Neurobiol. Aging 1997, 18, S1-S2.
-
(1997)
Neurobiol. Aging
, vol.18
-
-
-
24
-
-
33144489150
-
Diagnosis and management of dementia with Lewy bodies
-
McKeith, I. G., Dickson, D. W., Lowe, J., Emre, M. et al., Diagnosis and management of dementia with Lewy bodies. Neurology 2005, 65, 1863-1872.
-
(2005)
Neurology
, vol.65
, pp. 1863-1872
-
-
McKeith, I.G.1
Dickson, D.W.2
Lowe, J.3
Emre, M.4
-
25
-
-
70449436388
-
Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimers disease
-
Gozal, Y. M., Duong, D. M., Gearing, M., Cheng, D. et al., Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimers disease. J. Proteome Res. 2009, 8, 5069-5079.
-
(2009)
J. Proteome Res.
, vol.8
, pp. 5069-5079
-
-
Gozal, Y.M.1
Duong, D.M.2
Gearing, M.3
Cheng, D.4
-
26
-
-
78649865461
-
Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration
-
Herskowitz, J. H., Seyfried, N. T., Duong, D. M., Xia, Q. et al., Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration. J. Proteome Res. 2010, 9, 6368-6379.
-
(2010)
J. Proteome Res.
, vol.9
, pp. 6368-6379
-
-
Herskowitz, J.H.1
Seyfried, N.T.2
Duong, D.M.3
Xia, Q.4
-
27
-
-
79953221858
-
Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production
-
Herskowitz, J. H., Seyfried, N. T., Gearing, M., Kahn, R. A. et al., Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production. J. Biol. Chem. 2011, 286, 6117-6127.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 6117-6127
-
-
Herskowitz, J.H.1
Seyfried, N.T.2
Gearing, M.3
Kahn, R.A.4
-
28
-
-
77950658888
-
Multiplex SILAC analysis of a cellular TDP-43 proteinopathy model reveals protein inclusions associated with SUMOylation and diverse polyUb chains
-
Seyfried, N. T., Gozal, Y. M., Dammer, E. B., Xia, Q. et al., Multiplex SILAC analysis of a cellular TDP-43 proteinopathy model reveals protein inclusions associated with SUMOylation and diverse polyUb chains. Mol. Cell Proteomics 2010, 9, 705-718.
-
(2010)
Mol. Cell Proteomics
, vol.9
, pp. 705-718
-
-
Seyfried, N.T.1
Gozal, Y.M.2
Dammer, E.B.3
Xia, Q.4
-
29
-
-
0027212498
-
Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins
-
Frangioni, J. V., Neel, B. G., Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins. Anal. Biochem. 1993, 210, 179-187.
-
(1993)
Anal. Biochem.
, vol.210
, pp. 179-187
-
-
Frangioni, J.V.1
Neel, B.G.2
-
30
-
-
40849111819
-
Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase
-
Liu, Z., Jang, S.-W., Liu, X., Cheng, D. et al., Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase. Mol. Cell 2008, 29, 665-678.
-
(2008)
Mol. Cell
, vol.29
, pp. 665-678
-
-
Liu, Z.1
Jang, S.-W.2
Liu, X.3
Cheng, D.4
-
31
-
-
0041876230
-
Biosynthetic processing of cathepsins and lysosomal degradation are Abolished in asparaginyl endopeptidase-deficient mice
-
Shirahama-Noda, K., Yamamoto, A., Sugihara, K., Hashimoto, N. et al., Biosynthetic processing of cathepsins and lysosomal degradation are Abolished in asparaginyl endopeptidase-deficient mice. J. Biol. Chem. 2003, 278, 33194-33199.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33194-33199
-
-
Shirahama-Noda, K.1
Yamamoto, A.2
Sugihara, K.3
Hashimoto, N.4
-
32
-
-
0030992979
-
Cloning, isolation, and characterization of mammalian legumain, an asparaginyl endopeptidase
-
Chen, J.-M., Dando, P. M., Rawlings, N. D., Brown, M. A. et al., Cloning, isolation, and characterization of mammalian legumain, an asparaginyl endopeptidase. J. Biol. Chem. 1997, 272, 8090-8098.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8090-8098
-
-
Chen, J.-M.1
Dando, P.M.2
Rawlings, N.D.3
Brown, M.A.4
-
33
-
-
84855828470
-
New aspects of the molecular evolution of legumains, Asn-specific cysteine proteinases
-
Shutov, A. D., Blattner, F. R., Kakhovskaya, I. A., Müntz, K., New aspects of the molecular evolution of legumains, Asn-specific cysteine proteinases. J. Plant Physiol. 2012, 169, 319-321.
-
(2012)
J. Plant Physiol
, vol.169
, pp. 319-321
-
-
Shutov, A.D.1
Blattner, F.R.2
Kakhovskaya, I.A.3
Müntz, K.4
-
34
-
-
0032542285
-
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation
-
Manoury, B., Hewitt, E. W., Morrice, N., Dando, P. M. et al., An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation. Nature 1998, 396, 695-699.
-
(1998)
Nature
, vol.396
, pp. 695-699
-
-
Manoury, B.1
Hewitt, E.W.2
Morrice, N.3
Dando, P.M.4
-
35
-
-
26244458694
-
Asparaginyl endopeptidase: case history of a class II MHC compartment protease
-
Watts, C., Matthews, S. P., Mazzeo, D., Manoury, B. et al., Asparaginyl endopeptidase: case history of a class II MHC compartment protease. Immunol. Rev. 2005, 207, 218-228.
-
(2005)
Immunol. Rev.
, vol.207
, pp. 218-228
-
-
Watts, C.1
Matthews, S.P.2
Mazzeo, D.3
Manoury, B.4
-
36
-
-
70449477746
-
Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic eells
-
Sepulveda, F. E., Maschalidi, S., Colisson, R., Heslop, L. et al., Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic eells. Immunity 2009, 31, 737-748.
-
(2009)
Immunity
, vol.31
, pp. 737-748
-
-
Sepulveda, F.E.1
Maschalidi, S.2
Colisson, R.3
Heslop, L.4
-
37
-
-
80052967905
-
TDP-43: the relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration
-
Baloh, R. H., TDP-43: the relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration. FEBS J. 2011, 278, 3539-3549.
-
(2011)
FEBS J.
, vol.278
, pp. 3539-3549
-
-
Baloh, R.H.1
-
38
-
-
78651394950
-
Implications of the prion-related Q/N domains in TDP-43 and FUS
-
Udan, M., Baloh, R. H., Implications of the prion-related Q/N domains in TDP-43 and FUS. Prion 2011, 5, 1-5.
-
(2011)
Prion
, vol.5
, pp. 1-5
-
-
Udan, M.1
Baloh, R.H.2
-
39
-
-
80155157847
-
The seeds of neurodegeneration: prion-like spreading in ALS
-
Polymenidou, M., Cleveland, Don W., The seeds of neurodegeneration: prion-like spreading in ALS. Cell 2011, 147, 498-508.
-
(2011)
Cell
, vol.147
, pp. 498-508
-
-
Polymenidou, M.1
Cleveland, D.W.2
-
40
-
-
77953890823
-
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
-
Lagier-Tourenne, C., Polymenidou, M., Cleveland, D. W., TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration. Hum. Mol. Genet. 2010, 19, R46-R64.
-
(2010)
Hum. Mol. Genet.
, vol.19
-
-
Lagier-Tourenne, C.1
Polymenidou, M.2
Cleveland, D.W.3
|