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Volumn 6, Issue , 2016, Pages

High-throughput proteomics reveal alarmins as amplifiers of tissue pathology and inflammation after spinal cord injury

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; AGER PROTEIN, RAT; ALARMIN; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 1; TLR4 PROTEIN, RAT; TOLL LIKE RECEPTOR 4;

EID: 84959107602     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep21607     Document Type: Article
Times cited : (78)

References (70)
  • 1
    • 81855175366 scopus 로고    scopus 로고
    • Inflammation and axon regeneration
    • Benowitz, L. I. & Popovich, P. G. Inflammation and axon regeneration. Curr Opin Neurol 24(6), 577-583 (2011).
    • (2011) Curr Opin Neurol , vol.24 , Issue.6 , pp. 577-583
    • Benowitz, L.I.1    Popovich, P.G.2
  • 2
    • 0742288565 scopus 로고    scopus 로고
    • Regeneration beyond the glial scar
    • Silver, J. & Miller, J. H. Regeneration beyond the glial scar. Nat Rev Neurosci 5(2), 146-156 (2004).
    • (2004) Nat Rev Neurosci , vol.5 , Issue.2 , pp. 146-156
    • Silver, J.1    Miller, J.H.2
  • 3
    • 84895950053 scopus 로고    scopus 로고
    • Nogo limits neural plasticity and recovery from injury
    • Schwab, M. E. & Strittmatter, S. M. Nogo limits neural plasticity and recovery from injury. Curr Opin Neurobiol 27, 53-60 (2014).
    • (2014) Curr Opin Neurobiol , vol.27 , pp. 53-60
    • Schwab, M.E.1    Strittmatter, S.M.2
  • 4
    • 0033180342 scopus 로고    scopus 로고
    • The glial scar and central nervous system repair
    • Fawcett, J. W. & Asher, R. A. The glial scar and central nervous system repair. Brain Res Bull 49(6), 377-391 (1999).
    • (1999) Brain Res Bull , vol.49 , Issue.6 , pp. 377-391
    • Fawcett, J.W.1    Asher, R.A.2
  • 5
    • 79960405675 scopus 로고    scopus 로고
    • Functional regeneration of respiratory pathways after spinal cord injury
    • Alilain, W. J., Horn, K. P., Hu, H., Dick, T. E. & Silver, J. Functional regeneration of respiratory pathways after spinal cord injury. Nature 475(7355), 196-200 (2011).
    • (2011) Nature , vol.475 , Issue.7355 , pp. 196-200
    • Alilain, W.J.1    Horn, K.P.2    Hu, H.3    Dick, T.E.4    Silver, J.5
  • 6
    • 0037061426 scopus 로고    scopus 로고
    • Chondroitinase ABC promotes functional recovery after spinal cord injury
    • Bradbury, E. J. et al. Chondroitinase ABC promotes functional recovery after spinal cord injury. Nature 416(6881), 636-640 (2002).
    • (2002) Nature , vol.416 , Issue.6881 , pp. 636-640
    • Bradbury, E.J.1
  • 7
    • 38649112309 scopus 로고    scopus 로고
    • CNS injury, glial scars and inflammation: Inhibitory extracellular matrices and regeneration failure
    • Fitch, M. T. & Silver, J. CNS injury, glial scars and inflammation: Inhibitory extracellular matrices and regeneration failure. Exp Neurol 209(2), 294-301 (2008).
    • (2008) Exp Neurol , vol.209 , Issue.2 , pp. 294-301
    • Fitch, M.T.1    Silver, J.2
  • 8
    • 84892555677 scopus 로고    scopus 로고
    • Manipulating the extracellular matrix and its role in brain and spinal cord plasticity and repair
    • Burnside, E. R. & Bradbury, E. J. Manipulating the extracellular matrix and its role in brain and spinal cord plasticity and repair. Neuropathol Appl Neurobiol 40(1), 26-59 (2014).
    • (2014) Neuropathol Appl Neurobiol , vol.40 , Issue.1 , pp. 26-59
    • Burnside, E.R.1    Bradbury, E.J.2
  • 9
    • 84882643038 scopus 로고    scopus 로고
    • Perivascular fibroblasts form the fibrotic scar after contusive spinal cord injury
    • Soderblom, C. et al. Perivascular fibroblasts form the fibrotic scar after contusive spinal cord injury. J Neurosci 33(34), 13882-13887 (2013).
    • (2013) J Neurosci , vol.33 , Issue.34 , pp. 13882-13887
    • Soderblom, C.1
  • 10
    • 84899446231 scopus 로고    scopus 로고
    • Large-scale chondroitin sulfate proteoglycan digestion with chondroitinase gene therapy leads to reduced pathology and modulates macrophage phenotype following spinal cord contusion injury
    • Bartus, K. et al. Large-scale chondroitin sulfate proteoglycan digestion with chondroitinase gene therapy leads to reduced pathology and modulates macrophage phenotype following spinal cord contusion injury. J Neurosci 34(14), 4822-4836 (2014).
    • (2014) J Neurosci , vol.34 , Issue.14 , pp. 4822-4836
    • Bartus, K.1
  • 11
    • 84914670481 scopus 로고    scopus 로고
    • Regulation of IL-10 by chondroitinase ABC promotes a distinct immune response following spinal cord injury
    • Didangelos, A., Iberl, M., Vinsland, E., Bartus, K. & Bradbury, E. J. Regulation of IL-10 by chondroitinase ABC promotes a distinct immune response following spinal cord injury. J Neurosci 34(49), 16424-16432 (2014).
    • (2014) J Neurosci , vol.34 , Issue.49 , pp. 16424-16432
    • Didangelos, A.1    Iberl, M.2    Vinsland, E.3    Bartus, K.4    Bradbury, E.J.5
  • 12
    • 67650502739 scopus 로고    scopus 로고
    • Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease
    • Midwood, K. et al. Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease. Nat Med 15(7), 774-780 (2009).
    • (2009) Nat Med , vol.15 , Issue.7 , pp. 774-780
    • Midwood, K.1
  • 14
    • 23644456849 scopus 로고    scopus 로고
    • The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages
    • Schaefer, L. et al. The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. J Clin Invest 115(8), 2223-2233 (2005).
    • (2005) J Clin Invest , vol.115 , Issue.8 , pp. 2223-2233
    • Schaefer, L.1
  • 15
    • 83755174410 scopus 로고    scopus 로고
    • The glial scar-monocyte interplay: A pivotal resolution phase in spinal cord repair
    • Shechter, R., Raposo, C., London, A., Sagi, I. & Schwartz, M. The glial scar-monocyte interplay: a pivotal resolution phase in spinal cord repair. PLoS One 6(12), e27969 (2011).
    • (2011) PLoS One , vol.6 , Issue.12
    • Shechter, R.1    Raposo, C.2    London, A.3    Sagi, I.4    Schwartz, M.5
  • 16
    • 77956496368 scopus 로고    scopus 로고
    • Proteomics characterization of extracellular space components in the human aorta
    • Didangelos, A. et al. Proteomics characterization of extracellular space components in the human aorta. Mol Cell Proteomics 9(9) 2048-2062 (2010).
    • (2010) Mol Cell Proteomics , vol.9 , Issue.9 , pp. 2048-2062
    • Didangelos, A.1
  • 17
    • 80051661224 scopus 로고    scopus 로고
    • Extracellular matrix composition and remodeling in human abdominal aortic aneurysms: A proteomics approach
    • Didangelos, A. et al. Extracellular matrix composition and remodeling in human abdominal aortic aneurysms: a proteomics approach. Mol Cell Proteomics 10(8), M111 008128 (2011).
    • (2011) Mol Cell Proteomics , vol.10 , Issue.8 , pp. M111008128
    • Didangelos, A.1
  • 18
    • 77649189116 scopus 로고    scopus 로고
    • Astrocytes: Biology and pathology
    • Sofroniew, M. V. & Vinters, H. V. Astrocytes: biology and pathology. Acta Neuropathol 119(1), 7-35 (2009).
    • (2009) Acta Neuropathol , vol.119 , Issue.1 , pp. 7-35
    • Sofroniew, M.V.1    Vinters, H.V.2
  • 19
    • 0027211820 scopus 로고
    • Nervous tissue proteoglycans
    • Margolis, R. K. & Margolis, R. U. Nervous tissue proteoglycans. Experientia 49(5), 429-446 (1993).
    • (1993) Experientia , vol.49 , Issue.5 , pp. 429-446
    • Margolis, R.K.1    Margolis, R.U.2
  • 20
    • 84892850576 scopus 로고    scopus 로고
    • Functional regeneration beyond the glial scar
    • Cregg, J. M. et al. Functional regeneration beyond the glial scar. Exp Neurol 253, 197-207 (2014).
    • (2014) Exp Neurol , vol.253 , pp. 197-207
    • Cregg, J.M.1
  • 21
    • 84913593330 scopus 로고    scopus 로고
    • Hematogenous macrophage depletion reduces the fibrotic scar and increases axonal growth after spinal cord injury
    • Zhu, Y. et al. Hematogenous macrophage depletion reduces the fibrotic scar and increases axonal growth after spinal cord injury. Neurobiol Dis 74, 114-125 (2015).
    • (2015) Neurobiol Dis , vol.74 , pp. 114-125
    • Zhu, Y.1
  • 22
    • 58149373436 scopus 로고    scopus 로고
    • Ceruloplasmin protects injured spinal cord from iron-mediated oxidative damage
    • Rathore, K. I. et al. Ceruloplasmin protects injured spinal cord from iron-mediated oxidative damage. J Neurosci 28(48), 12736-12747 (2008).
    • (2008) J Neurosci , vol.28 , Issue.48 , pp. 12736-12747
    • Rathore, K.I.1
  • 23
    • 0037437149 scopus 로고    scopus 로고
    • Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A
    • Xia, C. H. et al. Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A. J Cell Biol 161(1), 55-66 (2003).
    • (2003) J Cell Biol , vol.161 , Issue.1 , pp. 55-66
    • Xia, C.H.1
  • 24
    • 18044377786 scopus 로고    scopus 로고
    • Regulation of dense core vesicle release from PC12 cells by interaction between the D2 dopamine receptor and calcium-dependent activator protein for secretion (CAPS)
    • Binda, A. V., Kabbani, N. & Levenson, R. Regulation of dense core vesicle release from PC12 cells by interaction between the D2 dopamine receptor and calcium-dependent activator protein for secretion (CAPS). Biochem Pharmacol 69(10), 1451-1461 (2005).
    • (2005) Biochem Pharmacol , vol.69 , Issue.10 , pp. 1451-1461
    • Binda, A.V.1    Kabbani, N.2    Levenson, R.3
  • 25
    • 0032126699 scopus 로고    scopus 로고
    • Mutation in AP-3 delta in the mocha mouse links endosomal transport to storage deficiency in platelets, melanosomes, and synaptic vesicles
    • Kantheti, P. et al. Mutation in AP-3 delta in the mocha mouse links endosomal transport to storage deficiency in platelets, melanosomes, and synaptic vesicles. Neuron 21(1), 111-122 (1998).
    • (1998) Neuron , vol.21 , Issue.1 , pp. 111-122
    • Kantheti, P.1
  • 26
    • 84941051170 scopus 로고    scopus 로고
    • STRING v10: Protein-protein interaction networks, integrated over the tree of life
    • Szklarczyk, D. et al. STRING v10: protein-protein interaction networks, integrated over the tree of life. Nucleic Acids Res 43 (Database issue) D447-452 (2015).
    • (2015) Nucleic Acids Res , vol.43 , Issue.DATABASE ISSUE , pp. D447-452
    • Szklarczyk, D.1
  • 27
    • 0036529479 scopus 로고    scopus 로고
    • An efficient algorithm for large-scale detection of protein families
    • Enright, A. J., Van Dongen, S. & Ouzounis, C. A. An efficient algorithm for large-scale detection of protein families. Nucleic Acids Res 30(7), 1575-1584 (2002).
    • (2002) Nucleic Acids Res , vol.30 , Issue.7 , pp. 1575-1584
    • Enright, A.J.1    Van Dongen, S.2    Ouzounis, C.A.3
  • 28
    • 84859917115 scopus 로고    scopus 로고
    • Alterations in chondroitin sulfate proteoglycan expression occur both at and far from the site of spinal contusion injury
    • Andrews, E. M., Richards, R. J., Yin, F. Q., Viapiano, M. S. & Jakeman, L. B., Alterations in chondroitin sulfate proteoglycan expression occur both at and far from the site of spinal contusion injury. Exp Neurol 235(1), 174-187 (2012).
    • (2012) Exp Neurol , vol.235 , Issue.1 , pp. 174-187
    • Andrews, E.M.1    Richards, R.J.2    Yin, F.Q.3    Viapiano, M.S.4    Jakeman, L.B.5
  • 29
    • 4544335403 scopus 로고    scopus 로고
    • Spatial and temporal gene expression profiling of the contused rat spinal cord
    • Aimone, J. B., Leasure, J. L., Perreau, V. M. & Thallmair, M. Spatial and temporal gene expression profiling of the contused rat spinal cord. Exp Neurol 189(2), 204-221 (2004).
    • (2004) Exp Neurol , vol.189 , Issue.2 , pp. 204-221
    • Aimone, J.B.1    Leasure, J.L.2    Perreau, V.M.3    Thallmair, M.4
  • 30
    • 84907195162 scopus 로고    scopus 로고
    • Beyond tissue injury-damage-associated molecular patterns, toll-like receptors and inflammasomes also drive regeneration and fibrosis
    • Anders, H. J. & Schaefer, L. Beyond tissue injury-damage-associated molecular patterns, toll-like receptors and inflammasomes also drive regeneration and fibrosis. J Am Soc Nephrol 25(7), 1387-1400 (2014).
    • (2014) J Am Soc Nephrol , vol.25 , Issue.7 , pp. 1387-1400
    • Anders, H.J.1    Schaefer, L.2
  • 31
    • 77955383770 scopus 로고    scopus 로고
    • DAMPening inflammation by modulating TLR signalling
    • Piccinini, A. M. & Midwood, K. S. DAMPening inflammation by modulating TLR signalling. Mediators Inflamm 2010 (2010).
    • (2010) Mediators Inflamm , vol.2010
    • Piccinini, A.M.1    Midwood, K.S.2
  • 32
    • 77952293789 scopus 로고    scopus 로고
    • Calreticulin: Non-endoplasmic reticulum functions in physiology and disease
    • Gold, L. I. et al. Calreticulin: non-endoplasmic reticulum functions in physiology and disease. FASEB J 24(3), 665-683 (2010).
    • (2010) FASEB J , vol.24 , Issue.3 , pp. 665-683
    • Gold, L.I.1
  • 33
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira, S. & Takeda, K. Toll-like receptor signalling. Nat Rev Immunol 4(7), 499-511 (2004).
    • (2004) Nat Rev Immunol , vol.4 , Issue.7 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 34
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • Scaffidi, P., Misteli, T. & Bianchi, M. E. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418(6894), 191-195 (2002).
    • (2002) Nature , vol.418 , Issue.6894 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 35
    • 0033603241 scopus 로고    scopus 로고
    • RAGE mediates a novel proinflammatory axis: A central cell surface receptor for S100/calgranulin polypeptides
    • Hofmann, M. A. et al. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 97(7), 889-901 (1999).
    • (1999) Cell , vol.97 , Issue.7 , pp. 889-901
    • Hofmann, M.A.1
  • 36
    • 1542390447 scopus 로고    scopus 로고
    • Control of the expression of inflammatory response genes
    • Saklatvala, J., Dean, J. & Clark, A. Control of the expression of inflammatory response genes. Biochem Soc Symp(70), 95-106 (2003).
    • (2003) Biochem Soc Symp(70) , pp. 95-106
    • Saklatvala, J.1    Dean, J.2    Clark, A.3
  • 37
    • 11844305963 scopus 로고    scopus 로고
    • Attenuation of murine collagen-induced arthritis by a novel, potent, selective small molecule inhibitor of IkappaB Kinase 2, TPCA-1 (2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), occurs via reduction of proinflammatory cytokines and antigen-induced T cell Proliferation
    • Podolin, P. L. et al. Attenuation of murine collagen-induced arthritis by a novel, potent, selective small molecule inhibitor of IkappaB Kinase 2, TPCA-1 (2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), occurs via reduction of proinflammatory cytokines and antigen-induced T cell Proliferation. J Pharmacol Exp Ther 312(1), 373-381 (2005).
    • (2005) J Pharmacol Exp Ther , vol.312 , Issue.1 , pp. 373-381
    • Podolin, P.L.1
  • 38
    • 25844459154 scopus 로고    scopus 로고
    • NF-kappaB: Linking inflammation and immunity to cancer development and progression
    • Karin, M. & Greten, F. R. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol 5(10), 749-759 (2005).
    • (2005) Nat Rev Immunol , vol.5 , Issue.10 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 39
    • 0036943632 scopus 로고    scopus 로고
    • Increased expression of the putative axon growth-repulsive extracellular matrix molecule, keratan sulphate proteoglycan, following traumatic injury of the adult rat spinal cord
    • Krautstrunk, M. et al. Increased expression of the putative axon growth-repulsive extracellular matrix molecule, keratan sulphate proteoglycan, following traumatic injury of the adult rat spinal cord. Acta Neuropathol 104(6), 592-600 (2002).
    • (2002) Acta Neuropathol , vol.104 , Issue.6 , pp. 592-600
    • Krautstrunk, M.1
  • 40
    • 34447134133 scopus 로고    scopus 로고
    • SPARC from olfactory ensheathing cells stimulates Schwann cells to promote neurite outgrowth and enhances spinal cord repair
    • Au, E. et al. SPARC from olfactory ensheathing cells stimulates Schwann cells to promote neurite outgrowth and enhances spinal cord repair. J Neurosci 27(27), 7208-7221 (2007).
    • (2007) J Neurosci , vol.27 , Issue.27 , pp. 7208-7221
    • Au, E.1
  • 41
    • 84893664794 scopus 로고    scopus 로고
    • Astroglial-derived periostin promotes axonal regeneration after spinal cord injury
    • Shih, C. H., Lacagnina, M., Leuer-Bisciotti, K. & Proschel, C. Astroglial-derived periostin promotes axonal regeneration after spinal cord injury. J Neurosci 34(7), 2438-2443 (2014).
    • (2014) J Neurosci , vol.34 , Issue.7 , pp. 2438-2443
    • Shih, C.H.1    Lacagnina, M.2    Leuer-Bisciotti, K.3    Proschel, C.4
  • 42
    • 84857656575 scopus 로고    scopus 로고
    • Distinct spatio-temporal extracellular matrix accumulation within demyelinated spinal cord lesions in Theiler's murine encephalomyelitis
    • Haist, V., Ulrich, R., Kalkuhl, A., Deschl, U. & Baumgartner, W. Distinct spatio-temporal extracellular matrix accumulation within demyelinated spinal cord lesions in Theiler's murine encephalomyelitis. Brain Pathol 22(2), 188-204 (2012).
    • (2012) Brain Pathol , vol.22 , Issue.2 , pp. 188-204
    • Haist, V.1    Ulrich, R.2    Kalkuhl, A.3    Deschl, U.4    Baumgartner, W.5
  • 43
    • 4644329002 scopus 로고    scopus 로고
    • Galectin-1 expression correlates with the regenerative potential of rubrospinal and spinal motoneurons
    • McGraw, J. et al. Galectin-1 expression correlates with the regenerative potential of rubrospinal and spinal motoneurons. Neuroscience 128(4), 713-719 (2004).
    • (2004) Neuroscience , vol.128 , Issue.4 , pp. 713-719
    • McGraw, J.1
  • 44
    • 84920125516 scopus 로고    scopus 로고
    • Galectin-1 in injured rat spinal cord: Implications for macrophage phagocytosis and neural repair
    • Gaudet, A. D., Sweet, D. R., Polinski, N. K., Guan, Z. & Popovich, P. G. Galectin-1 in injured rat spinal cord: implications for macrophage phagocytosis and neural repair. Mol Cell Neurosci 64, 84-94 (2015).
    • (2015) Mol Cell Neurosci , vol.64 , pp. 84-94
    • Gaudet, A.D.1    Sweet, D.R.2    Polinski, N.K.3    Guan, Z.4    Popovich, P.G.5
  • 45
    • 84865781711 scopus 로고    scopus 로고
    • Characterization of inflammatory gene expression and galectin-3 function after spinal cord injury in mice
    • Pajoohesh-Ganji, A., Knoblach, S. M., Faden, A. I. & Byrnes, K. R. Characterization of inflammatory gene expression and galectin-3 function after spinal cord injury in mice. Brain Res 1475, 96-105 (2012).
    • (2012) Brain Res , vol.1475 , pp. 96-105
    • Pajoohesh-Ganji, A.1    Knoblach, S.M.2    Faden, A.I.3    Byrnes, K.R.4
  • 46
    • 34948835806 scopus 로고    scopus 로고
    • TLR4 activation mediates kidney ischemia/reperfusion injury
    • Wu, H. et al. TLR4 activation mediates kidney ischemia/reperfusion injury. J Clin Invest 117(10), 2847-2859 (2007).
    • (2007) J Clin Invest , vol.117 , Issue.10 , pp. 2847-2859
    • Wu, H.1
  • 47
    • 0035971217 scopus 로고    scopus 로고
    • The extra domain A of fibronectin activates Toll-like receptor 4
    • Okamura, Y. et al. The extra domain A of fibronectin activates Toll-like receptor 4. J Biol Chem 276(13), 10229-10233 (2001).
    • (2001) J Biol Chem , vol.276 , Issue.13 , pp. 10229-10233
    • Okamura, Y.1
  • 48
    • 84860166974 scopus 로고    scopus 로고
    • Alternatively-spliced extra domain A of fibronectin promotes acute inflammation and brain injury after cerebral ischemia in mice
    • Khan, M. M. et al. Alternatively-spliced extra domain A of fibronectin promotes acute inflammation and brain injury after cerebral ischemia in mice. Stroke 43(5), 1376-1382 (2012).
    • (2012) Stroke , vol.43 , Issue.5 , pp. 1376-1382
    • Khan, M.M.1
  • 49
    • 40049101198 scopus 로고    scopus 로고
    • Selective proinflammatory activation of astrocytes by high-mobility group box 1 protein signaling
    • Pedrazzi, M. et al. Selective proinflammatory activation of astrocytes by high-mobility group box 1 protein signaling. J Immunol 179(12), 8525-8532 (2007).
    • (2007) J Immunol , vol.179 , Issue.12 , pp. 8525-8532
    • Pedrazzi, M.1
  • 50
    • 33745788420 scopus 로고    scopus 로고
    • HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain
    • Kim, J. B. et al. HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain. J Neurosci 26(24), 6413-6421 (2006).
    • (2006) J Neurosci , vol.26 , Issue.24 , pp. 6413-6421
    • Kim, J.B.1
  • 52
    • 34250182782 scopus 로고    scopus 로고
    • Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury
    • Kigerl, K. A. et al. Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury. J Neurochem 102(1), 37-50 (2007).
    • (2007) J Neurochem , vol.102 , Issue.1 , pp. 37-50
    • Kigerl, K.A.1
  • 53
    • 35848963223 scopus 로고    scopus 로고
    • Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease
    • Walter, S. et al. Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease. Cell Physiol Biochem 20(6), 947-956 (2007).
    • (2007) Cell Physiol Biochem , vol.20 , Issue.6 , pp. 947-956
    • Walter, S.1
  • 54
    • 81855163367 scopus 로고    scopus 로고
    • High-mobility group box-1 and its receptors contribute to proinflammatory response in the acute phase of spinal cord injury in rats
    • Chen, K. B. et al. High-mobility group box-1 and its receptors contribute to proinflammatory response in the acute phase of spinal cord injury in rats. Spine (Phila Pa 1976) 36(25), 2122-2129 (2011).
    • (2011) Spine (Phila Pa 1976 , vol.36 , Issue.25 , pp. 2122-2129
    • Chen, K.B.1
  • 55
    • 84859402297 scopus 로고    scopus 로고
    • Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury
    • Sato, A. et al. Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury. J Neuroinflammation 9, 65 (2012).
    • (2012) J Neuroinflammation , vol.9 , pp. 65
    • Sato, A.1
  • 56
    • 67650724069 scopus 로고    scopus 로고
    • Regulation and function of NF-kappaB transcription factors in the immune system
    • Vallabhapurapu, S. & Karin, M. Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol 27, 693-733 (2009).
    • (2009) Annu Rev Immunol , vol.27 , pp. 693-733
    • Vallabhapurapu, S.1    Karin, M.2
  • 57
    • 0032080219 scopus 로고    scopus 로고
    • Traumatic spinal cord injury induces nuclear factor-kappaB activation
    • Bethea, J. R. et al. Traumatic spinal cord injury induces nuclear factor-kappaB activation. J Neurosci 18(9), 3251-3260 (1998).
    • (1998) J Neurosci , vol.18 , Issue.9 , pp. 3251-3260
    • Bethea, J.R.1
  • 59
    • 9244236078 scopus 로고    scopus 로고
    • A FADD-dependent innate immune mechanism in mammalian cells
    • Balachandran, S., Thomas, E. & Barber, G. N. A FADD-dependent innate immune mechanism in mammalian cells. Nature 432(7015), 401-405 (2004).
    • (2004) Nature , vol.432 , Issue.7015 , pp. 401-405
    • Balachandran, S.1    Thomas, E.2    Barber, G.N.3
  • 61
    • 0024368411 scopus 로고
    • Interleukin 1 and tumour necrosis factor increase phosphorylation of the small heat shock protein. Effects in fibroblasts, Hep G2 and U937 cells
    • Kaur, P., Welch, W. J. & Saklatvala, J. Interleukin 1 and tumour necrosis factor increase phosphorylation of the small heat shock protein. Effects in fibroblasts, Hep G2 and U937 cells. FEBS Lett 258(2), 269-273 (1989).
    • (1989) FEBS Lett , vol.258 , Issue.2 , pp. 269-273
    • Kaur, P.1    Welch, W.J.2    Saklatvala, J.3
  • 62
    • 79951851076 scopus 로고    scopus 로고
    • Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injury
    • Hellal, F. et al. Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injury. Science 331(6019), 928-931 (2011).
    • (2011) Science , vol.331 , Issue.6019 , pp. 928-931
    • Hellal, F.1
  • 63
    • 84892741034 scopus 로고    scopus 로고
    • Reactive gliosis and the multicellular response to CNS damage and disease
    • Burda, J. E. & Sofroniew, M. V. Reactive gliosis and the multicellular response to CNS damage and disease. Neuron 81(2), 229-248 (2014).
    • (2014) Neuron , vol.81 , Issue.2 , pp. 229-248
    • Burda, J.E.1    Sofroniew, M.V.2
  • 64
    • 84880851472 scopus 로고    scopus 로고
    • Glial scar borders are formed by newly proliferated, elongated astrocytes that interact to corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after spinal cord injury
    • Wanner, I. B. et al. Glial scar borders are formed by newly proliferated, elongated astrocytes that interact to corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after spinal cord injury. J Neurosci 33(31), 12870-12886 (2013).
    • (2013) J Neurosci , vol.33 , Issue.31 , pp. 12870-12886
    • Wanner, I.B.1
  • 65
    • 84884545941 scopus 로고    scopus 로고
    • Short hairpin RNA against PTEN enhances regenerative growth of corticospinal tract axons after spinal cord injury
    • Zukor, K. et al. Short hairpin RNA against PTEN enhances regenerative growth of corticospinal tract axons after spinal cord injury. J Neurosci 33(39), 15350-15361 (2013).
    • (2013) J Neurosci , vol.33 , Issue.39 , pp. 15350-15361
    • Zukor, K.1
  • 66
    • 79960099283 scopus 로고    scopus 로고
    • A pericyte origin of spinal cord scar tissue
    • Goritz, C. et al. A pericyte origin of spinal cord scar tissue. Science 333(6039), 238-242 (2011).
    • (2011) Science , vol.333 , Issue.6039 , pp. 238-242
    • Goritz, C.1
  • 67
    • 0344375091 scopus 로고    scopus 로고
    • Experimental modeling of spinal cord injury: Characterization of a force-defined injury device
    • Scheff, S. W., Rabchevsky, A. G., Fugaccia, I., Main, J. A. & Lumpp, J. E., Jr., Experimental modeling of spinal cord injury: characterization of a force-defined injury device. J Neurotrauma 20(2), 179-193 (2003).
    • (2003) J Neurotrauma , vol.20 , Issue.2 , pp. 179-193
    • Scheff, S.W.1    Rabchevsky, A.G.2    Fugaccia, I.3    Main, J.A.4    Lumpp, J.E.5
  • 68
    • 67349266694 scopus 로고    scopus 로고
    • Universal sample preparation method for proteome analysis
    • Wisniewski, J. R., Zougman, A., Nagaraj, N. & Mann, M. Universal sample preparation method for proteome analysis. Nat Methods 6(5), 359-362 (2009).
    • (2009) Nat Methods , vol.6 , Issue.5 , pp. 359-362
    • Wisniewski, J.R.1    Zougman, A.2    Nagaraj, N.3    Mann, M.4
  • 69
    • 0037108887 scopus 로고    scopus 로고
    • Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search
    • Keller, A., Nesvizhskii, A. I., Kolker, E. & Aebersold, R. Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal Chem 74(20), 5383-5392 (2002).
    • (2002) Anal Chem , vol.74 , Issue.20 , pp. 5383-5392
    • Keller, A.1    Nesvizhskii, A.I.2    Kolker, E.3    Aebersold, R.4
  • 70
    • 0042338362 scopus 로고    scopus 로고
    • A statistical model for identifying proteins by tandem mass spectrometry
    • Nesvizhskii, A. I., Keller, A., Kolker, E. & Aebersold, R. A statistical model for identifying proteins by tandem mass spectrometry. Anal Chem 75(17), 4646-4658 (2003).
    • (2003) Anal Chem , vol.75 , Issue.17 , pp. 4646-4658
    • Nesvizhskii, A.I.1    Keller, A.2    Kolker, E.3    Aebersold, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.