Systemic administration of epothilone B promotes axon regeneration after spinal cord injury

Science

Volumn 348, Issue 6232, 2015, Pages 347-352

  Ruschel, Jörg ^a   Hellal, Farida ^a,g   Flynn, Kevin C ^a,h   Dupraz, Sebastian ^a   Elliott, David A ^a   Tedeschi, Andrea ^a   Bates, Margaret ^b   Sliwinski, Christopher ^c   Brook, Gary ^d,e   Dobrindt, Kristina ^f   Peitz, Michael ^f   Brüstle, Oliver ^f   Norenberg, Michael D ^b   Blesch, Armin ^c   Weidner, Norbert ^c   Bunge, Mary Bartlett ^b   Bixby, John L ^b   Bradke, Frank ^a  

^a GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^d RWTH AACHEN UNIVERSITY   (Germany)

^e JARA Jülich Aachen Research Alliance Future Information Technology   (Germany)

^f UNIVERSITY OF BONN   (Germany)

^g LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^h MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EPOTHILONE B; EPOTHILONE DERIVATIVE; TUBULIN MODULATOR;

DRUG; INHIBITION; LESION; NERVOUS SYSTEM; REGENERATION; STABILIZATION;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; FIBROBLAST; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; MOTOR PERFORMANCE; MOUSE; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NONHUMAN; PERMEABILITY BARRIER; POLARIZATION; PRIORITY JOURNAL; RAT; SCAR FORMATION; SPINAL CORD INJURY; ANIMAL; AXON; CELL MOTION; CELL POLARITY; CICATRIX; DRUG EFFECTS; MENINX; MOTOR ACTIVITY; NERVE CELL; NERVE REGENERATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPINAL CORD INJURIES;

RODENTIA;

ANIMALS; AXONS; CELL MOVEMENT; CELL POLARITY; CICATRIX; EPOTHILONES; FIBROBLASTS; HUMANS; MENINGES; MOTOR ACTIVITY; NERVE REGENERATION; NEURONS; RATS; SPINAL CORD INJURIES; TUBULIN MODULATORS;

EID: 84927715105     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaa2958     Document Type: Article

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