메뉴 건너뛰기




Volumn 2, Issue 1, 2016, Pages 27-37

A Dynamical Framework for the All-or-None G1/S Transition

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A2; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; DNA; SMALL INTERFERING RNA; ANAPHASE PROMOTING COMPLEX; CELL CYCLE PROTEIN;

EID: 84958236911     PISSN: 24054712     EISSN: 24054720     Source Type: Journal    
DOI: 10.1016/j.cels.2016.01.001     Document Type: Article
Times cited : (98)

References (73)
  • 1
    • 84959852003 scopus 로고    scopus 로고
    • The history and future of targeting cyclin-dependent kinases in cancer therapy
    • U. Asghar, A.K. Witkiewicz, N.C. Turner, and E.S. Knudsen The history and future of targeting cyclin-dependent kinases in cancer therapy Nat. Rev. Drug Discov. 14 2015 130 146
    • (2015) Nat. Rev. Drug Discov. , vol.14 , pp. 130-146
    • Asghar, U.1    Witkiewicz, A.K.2    Turner, N.C.3    Knudsen, E.S.4
  • 2
    • 1642378661 scopus 로고    scopus 로고
    • Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
    • T. Bashir, N.V. Dorrello, V. Amador, D. Guardavaccaro, and M. Pagano Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase Nature 428 2004 190 193
    • (2004) Nature , vol.428 , pp. 190-193
    • Bashir, T.1    Dorrello, N.V.2    Amador, V.3    Guardavaccaro, D.4    Pagano, M.5
  • 4
    • 0021435557 scopus 로고
    • A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer
    • M. Boshart, L. Gissmann, H. Ikenberg, A. Kleinheinz, W. Scheurlen, and H. zur Hausen A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer EMBO J. 3 1984 1151 1157
    • (1984) EMBO J. , vol.3 , pp. 1151-1157
    • Boshart, M.1    Gissmann, L.2    Ikenberg, H.3    Kleinheinz, A.4    Scheurlen, W.5    Zur Hausen, H.6
  • 6
    • 0033176887 scopus 로고    scopus 로고
    • SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
    • A.C. Carrano, E. Eytan, A. Hershko, and M. Pagano SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27 Nat. Cell Biol. 1 1999 193 199
    • (1999) Nat. Cell Biol. , vol.1 , pp. 193-199
    • Carrano, A.C.1    Eytan, E.2    Hershko, A.3    Pagano, M.4
  • 7
    • 75749143909 scopus 로고    scopus 로고
    • Origin of irreversibility of cell cycle start in budding yeast
    • G. Charvin, C. Oikonomou, E.D. Siggia, and F.R. Cross Origin of irreversibility of cell cycle start in budding yeast PLoS Biol. 8 2010 e1000284
    • (2010) PLoS Biol. , vol.8 , pp. e1000284
    • Charvin, G.1    Oikonomou, C.2    Siggia, E.D.3    Cross, F.R.4
  • 9
    • 41149150219 scopus 로고    scopus 로고
    • The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy
    • I.M. Chu, L. Hengst, and J.M. Slingerland The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy Nat. Rev. Cancer 8 2008 253 267
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 253-267
    • Chu, I.M.1    Hengst, L.2    Slingerland, J.M.3
  • 13
    • 0035795414 scopus 로고    scopus 로고
    • Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase
    • N. den Elzen, and J. Pines Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase J. Cell Biol. 153 2001 121 136
    • (2001) J. Cell Biol. , vol.153 , pp. 121-136
    • Den Elzen, N.1    Pines, J.2
  • 14
    • 34248216452 scopus 로고    scopus 로고
    • Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C
    • B. Di Fiore, and J. Pines Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C J. Cell Biol. 177 2007 425 437
    • (2007) J. Cell Biol. , vol.177 , pp. 425-437
    • Di Fiore, B.1    Pines, J.2
  • 15
    • 0026698263 scopus 로고
    • Association of human cyclin e with a periodic G1-S phase protein kinase
    • V. Dulić, E. Lees, and S.I. Reed Association of human cyclin E with a periodic G1-S phase protein kinase Science 257 1992 1958 1961
    • (1992) Science , vol.257 , pp. 1958-1961
    • Dulić, V.1    Lees, E.2    Reed, S.I.3
  • 16
    • 2942707103 scopus 로고
    • Papillomavirus sequences integrate near cellular oncogenes in some cervical carcinomas
    • M. Dürst, C.M. Croce, L. Gissmann, E. Schwarz, and K. Huebner Papillomavirus sequences integrate near cellular oncogenes in some cervical carcinomas Proc. Natl. Acad. Sci. USA 84 1987 1070 1074
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 1070-1074
    • Dürst, M.1    Croce, C.M.2    Gissmann, L.3    Schwarz, E.4    Huebner, K.5
  • 18
    • 15844384256 scopus 로고    scopus 로고
    • A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice
    • M.L. Fero, M. Rivkin, M. Tasch, P. Porter, C.E. Carow, E. Firpo, K. Polyak, L.H. Tsai, V. Broudy, R.M. Perlmutter, and et al. A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice Cell 85 1996 733 744
    • (1996) Cell , vol.85 , pp. 733-744
    • Fero, M.L.1    Rivkin, M.2    Tasch, M.3    Porter, P.4    Carow, C.E.5    Firpo, E.6    Polyak, K.7    Tsai, L.H.8    Broudy, V.9    Perlmutter, R.M.10
  • 19
    • 0035795408 scopus 로고    scopus 로고
    • Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint
    • S. Geley, E. Kramer, C. Gieffers, J. Gannon, J.M. Peters, and T. Hunt Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint J. Cell Biol. 153 2001 137 148
    • (2001) J. Cell Biol. , vol.153 , pp. 137-148
    • Geley, S.1    Kramer, E.2    Gieffers, C.3    Gannon, J.4    Peters, J.M.5    Hunt, T.6
  • 22
    • 3042721656 scopus 로고    scopus 로고
    • Cell cycle-dependent regulation of a human DNA helicase that localizes in DNA damage foci
    • J. Gu, X. Xia, P. Yan, H. Liu, V.N. Podust, A.B. Reynolds, and E. Fanning Cell cycle-dependent regulation of a human DNA helicase that localizes in DNA damage foci Mol. Biol. Cell 15 2004 3320 3332
    • (2004) Mol. Biol. Cell , vol.15 , pp. 3320-3332
    • Gu, J.1    Xia, X.2    Yan, P.3    Liu, H.4    Podust, V.N.5    Reynolds, A.B.6    Fanning, E.7
  • 24
    • 78650446336 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor p27 as a prognostic biomarker and potential cancer therapeutic target
    • D.D. Hershko Cyclin-dependent kinase inhibitor p27 as a prognostic biomarker and potential cancer therapeutic target Future Oncol. 6 2010 1837 1847
    • (2010) Future Oncol. , vol.6 , pp. 1837-1847
    • Hershko, D.D.1
  • 25
    • 0036095082 scopus 로고    scopus 로고
    • E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)
    • J.Y. Hsu, J.D. Reimann, C.S. Sørensen, J. Lukas, and P.K. Jackson E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1) Nat. Cell Biol. 4 2002 358 366
    • (2002) Nat. Cell Biol. , vol.4 , pp. 358-366
    • Hsu, J.Y.1    Reimann, J.D.2    Sørensen, C.S.3    Lukas, J.4    Jackson, P.K.5
  • 31
    • 0032776303 scopus 로고    scopus 로고
    • Molecular interaction map of the mammalian cell cycle control and DNA repair systems
    • K.W. Kohn Molecular interaction map of the mammalian cell cycle control and DNA repair systems Mol. Biol. Cell 10 1999 2703 2734
    • (1999) Mol. Biol. Cell , vol.10 , pp. 2703-2734
    • Kohn, K.W.1
  • 33
    • 0024311904 scopus 로고
    • Amplification of the integrated viral transforming genes of human papillomavirus 18 and its 5′-flanking cellular sequence located near the myc protooncogene in HeLa cells
    • P.A. Lazo, J.A. DiPaolo, and N.C. Popescu Amplification of the integrated viral transforming genes of human papillomavirus 18 and its 5′-flanking cellular sequence located near the myc protooncogene in HeLa cells Cancer Res. 49 1989 4305 4310
    • (1989) Cancer Res. , vol.49 , pp. 4305-4310
    • Lazo, P.A.1    DiPaolo, J.A.2    Popescu, N.C.3
  • 35
    • 0033592688 scopus 로고    scopus 로고
    • Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex
    • C. Lukas, C.S. Sørensen, E. Kramer, E. Santoni-Rugiu, C. Lindeneg, J.M. Peters, J. Bartek, and J. Lukas Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex Nature 401 1999 815 818
    • (1999) Nature , vol.401 , pp. 815-818
    • Lukas, C.1    Sørensen, C.S.2    Kramer, E.3    Santoni-Rugiu, E.4    Lindeneg, C.5    Peters, J.M.6    Bartek, J.7    Lukas, J.8
  • 36
    • 33846534165 scopus 로고    scopus 로고
    • The APC/C inhibitor, Emi1, is essential for prevention of rereplication
    • Y.J. Machida, and A. Dutta The APC/C inhibitor, Emi1, is essential for prevention of rereplication Genes Dev. 21 2007 184 194
    • (2007) Genes Dev. , vol.21 , pp. 184-194
    • Machida, Y.J.1    Dutta, A.2
  • 37
    • 20444410393 scopus 로고    scopus 로고
    • Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1)
    • A. Martín, J. Odajima, S.L. Hunt, P. Dubus, S. Ortega, M. Malumbres, and M. Barbacid Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1) Cancer Cell 7 2005 591 598
    • (2005) Cancer Cell , vol.7 , pp. 591-598
    • Martín, A.1    Odajima, J.2    Hunt, S.L.3    Dubus, P.4    Ortega, S.5    Malumbres, M.6    Barbacid, M.7
  • 38
    • 33748279259 scopus 로고    scopus 로고
    • Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor
    • J.J. Miller, M.K. Summers, D.V. Hansen, M.V. Nachury, N.L. Lehman, A. Loktev, and P.K. Jackson Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor Genes Dev. 20 2006 2410 2420
    • (2006) Genes Dev. , vol.20 , pp. 2410-2420
    • Miller, J.J.1    Summers, M.K.2    Hansen, D.V.3    Nachury, M.V.4    Lehman, N.L.5    Loktev, A.6    Jackson, P.K.7
  • 39
    • 0033135878 scopus 로고    scopus 로고
    • Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation
    • A. Montagnoli, F. Fiore, E. Eytan, A.C. Carrano, G.F. Draetta, A. Hershko, and M. Pagano Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation Genes Dev. 13 1999 1181 1189
    • (1999) Genes Dev. , vol.13 , pp. 1181-1189
    • Montagnoli, A.1    Fiore, F.2    Eytan, E.3    Carrano, A.C.4    Draetta, G.F.5    Hershko, A.6    Pagano, M.7
  • 40
    • 77954955259 scopus 로고    scopus 로고
    • Human papillomavirus oncoproteins: Pathways to transformation
    • C.A. Moody, and L.A. Laimins Human papillomavirus oncoproteins: pathways to transformation Nat. Rev. Cancer 10 2010 550 560
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 550-560
    • Moody, C.A.1    Laimins, L.A.2
  • 41
    • 0031466305 scopus 로고    scopus 로고
    • Cyclin-dependent kinases: Engines, clocks, and microprocessors
    • D.O. Morgan Cyclin-dependent kinases: engines, clocks, and microprocessors Annu. Rev. Cell Dev. Biol. 13 1997 261 291
    • (1997) Annu. Rev. Cell Dev. Biol. , vol.13 , pp. 261-291
    • Morgan, D.O.1
  • 43
    • 0030010591 scopus 로고    scopus 로고
    • Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
    • K. Nakayama, N. Ishida, M. Shirane, A. Inomata, T. Inoue, N. Shishido, I. Horii, D.Y. Loh, and K. Nakayama Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors Cell 85 1996 707 720
    • (1996) Cell , vol.85 , pp. 707-720
    • Nakayama, K.1    Ishida, N.2    Shirane, M.3    Inomata, A.4    Inoue, T.5    Shishido, N.6    Horii, I.7    Loh, D.Y.8    Nakayama, K.9
  • 46
    • 0029583648 scopus 로고
    • Regulation of the cyclin e gene by transcription factor E2F1
    • K. Ohtani, J. DeGregori, and J.R. Nevins Regulation of the cyclin E gene by transcription factor E2F1 Proc. Natl. Acad. Sci. USA 92 1995 12146 12150
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 12146-12150
    • Ohtani, K.1    DeGregori, J.2    Nevins, J.R.3
  • 47
    • 84907893223 scopus 로고    scopus 로고
    • Basal p21 controls population heterogeneity in cycling and quiescent cell cycle states
    • K.W. Overton, S.L. Spencer, W.L. Noderer, T. Meyer, and C.L. Wang Basal p21 controls population heterogeneity in cycling and quiescent cell cycle states Proc. Natl. Acad. Sci. USA 111 2014 E4386 E4393
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. E4386-E4393
    • Overton, K.W.1    Spencer, S.L.2    Noderer, W.L.3    Meyer, T.4    Wang, C.L.5
  • 49
    • 0025090934 scopus 로고
    • Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B
    • J. Pines, and T. Hunter Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B Nature 346 1990 760 763
    • (1990) Nature , vol.346 , pp. 760-763
    • Pines, J.1    Hunter, T.2
  • 50
    • 54249138783 scopus 로고    scopus 로고
    • Rapid cycling and precocious termination of G1 phase in cells expressing CDK1AF
    • J.R. Pomerening, J.A. Ubersax, and J.E. Ferrell Jr. Rapid cycling and precocious termination of G1 phase in cells expressing CDK1AF Mol. Biol. Cell 19 2008 3426 3441
    • (2008) Mol. Biol. Cell , vol.19 , pp. 3426-3441
    • Pomerening, J.R.1    Ubersax, J.A.2    Ferrell, J.E.3
  • 56
    • 0028114987 scopus 로고
    • The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. Cerevisiae
    • E. Schwob, T. Böhm, M.D. Mendenhall, and K. Nasmyth The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae Cell 79 1994 233 244
    • (1994) Cell , vol.79 , pp. 233-244
    • Schwob, E.1    Böhm, T.2    Mendenhall, M.D.3    Nasmyth, K.4
  • 58
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • C.J. Sherr, and J.M. Roberts CDK inhibitors: positive and negative regulators of G1-phase progression Genes Dev. 13 1999 1501 1512
    • (1999) Genes Dev. , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 59
    • 47549106474 scopus 로고    scopus 로고
    • Positive feedback of G1 cyclins ensures coherent cell cycle entry
    • J.M. Skotheim, S. Di Talia, E.D. Siggia, and F.R. Cross Positive feedback of G1 cyclins ensures coherent cell cycle entry Nature 454 2008 291 296
    • (2008) Nature , vol.454 , pp. 291-296
    • Skotheim, J.M.1    Di Talia, S.2    Siggia, E.D.3    Cross, F.R.4
  • 60
    • 0001616078 scopus 로고    scopus 로고
    • A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression
    • C.S. Sørensen, C. Lukas, E.R. Kramer, J.M. Peters, J. Bartek, and J. Lukas A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression Mol. Cell. Biol. 21 2001 3692 3703
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3692-3703
    • Sørensen, C.S.1    Lukas, C.2    Kramer, E.R.3    Peters, J.M.4    Bartek, J.5    Lukas, J.6
  • 61
    • 84885614963 scopus 로고    scopus 로고
    • The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit
    • S.L. Spencer, S.D. Cappell, F.C. Tsai, K.W. Overton, C.L. Wang, and T. Meyer The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit Cell 155 2013 369 383
    • (2013) Cell , vol.155 , pp. 369-383
    • Spencer, S.L.1    Cappell, S.D.2    Tsai, F.C.3    Overton, K.W.4    Wang, C.L.5    Meyer, T.6
  • 62
    • 0041327168 scopus 로고    scopus 로고
    • Proliferation of cancer cells despite CDK2 inhibition
    • O. Tetsu, and F. McCormick Proliferation of cancer cells despite CDK2 inhibition Cancer Cell 3 2003 233 245
    • (2003) Cancer Cell , vol.3 , pp. 233-245
    • Tetsu, O.1    McCormick, F.2
  • 63
    • 0027742184 scopus 로고
    • Distinct roles for cyclin-dependent kinases in cell cycle control
    • S. van den Heuvel, and E. Harlow Distinct roles for cyclin-dependent kinases in cell cycle control Science 262 1993 2050 2054
    • (1993) Science , vol.262 , pp. 2050-2054
    • Van Den Heuvel, S.1    Harlow, E.2
  • 64
    • 84877764493 scopus 로고    scopus 로고
    • Molecular mechanisms creating bistable switches at cell cycle transitions
    • A. Verdugo, P.K. Vinod, J.J. Tyson, and B. Novak Molecular mechanisms creating bistable switches at cell cycle transitions Open Biol. 3 2013 120179
    • (2013) Open Biol. , vol.3 , pp. 120179
    • Verdugo, A.1    Vinod, P.K.2    Tyson, J.J.3    Novak, B.4
  • 65
    • 0030847760 scopus 로고    scopus 로고
    • Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27
    • J. Vlach, S. Hennecke, and B. Amati Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27 EMBO J. 16 1997 5334 5344
    • (1997) EMBO J. , vol.16 , pp. 5334-5344
    • Vlach, J.1    Hennecke, S.2    Amati, B.3
  • 66
    • 1642399624 scopus 로고    scopus 로고
    • Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
    • W. Wei, N.G. Ayad, Y. Wan, G.J. Zhang, M.W. Kirschner, and W.G. Kaelin Jr. Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex Nature 428 2004 194 198
    • (2004) Nature , vol.428 , pp. 194-198
    • Wei, W.1    Ayad, N.G.2    Wan, Y.3    Zhang, G.J.4    Kirschner, M.W.5    Kaelin, W.G.6
  • 67
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • R.A. Weinberg The retinoblastoma protein and cell cycle control Cell 81 1995 323 330
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 68
    • 0029737650 scopus 로고    scopus 로고
    • Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin e
    • K.A. Won, and S.I. Reed Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E EMBO J. 15 1996 4182 4193
    • (1996) EMBO J. , vol.15 , pp. 4182-4193
    • Won, K.A.1    Reed, S.I.2
  • 69
    • 84886620259 scopus 로고    scopus 로고
    • Design principles of the yeast G1/S switch
    • X. Yang, K.Y. Lau, V. Sevim, and C. Tang Design principles of the yeast G1/S switch PLoS Biol. 11 2013 e1001673
    • (2013) PLoS Biol. , vol.11 , pp. e1001673
    • Yang, X.1    Lau, K.Y.2    Sevim, V.3    Tang, C.4
  • 70
    • 43149108161 scopus 로고    scopus 로고
    • A bistable Rb-E2F switch underlies the restriction point
    • G. Yao, T.J. Lee, S. Mori, J.R. Nevins, and L. You A bistable Rb-E2F switch underlies the restriction point Nat. Cell Biol. 10 2008 476 482
    • (2008) Nat. Cell Biol. , vol.10 , pp. 476-482
    • Yao, G.1    Lee, T.J.2    Mori, S.3    Nevins, J.R.4    You, L.5
  • 71
    • 84894240500 scopus 로고    scopus 로고
    • Uncovering the role of APC-Cdh1 in generating the dynamics of S-phase onset
    • X. Yuan, J. Srividhya, T. De Luca, J.H. Lee, and J.R. Pomerening Uncovering the role of APC-Cdh1 in generating the dynamics of S-phase onset Mol. Biol. Cell 25 2014 441 456
    • (2014) Mol. Biol. Cell , vol.25 , pp. 441-456
    • Yuan, X.1    Srividhya, J.2    De Luca, T.3    Lee, J.H.4    Pomerening, J.R.5
  • 72
    • 0032573374 scopus 로고    scopus 로고
    • Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex
    • W. Zachariae, M. Schwab, K. Nasmyth, and W. Seufert Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex Science 282 1998 1721 1724
    • (1998) Science , vol.282 , pp. 1721-1724
    • Zachariae, W.1    Schwab, M.2    Nasmyth, K.3    Seufert, W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.