Start and the restriction point

Current Opinion in Cell Biology

Volumn 25, Issue 6, 2013, Pages 717-723

  Johnson, Amy ^a   Skotheim, Jan M ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A; CYCLIN D; CYCLIN DEPENDENT KINASE 1; CYCLIN E; PROTEIN P53; PROTEIN TYROSINE PHOSPHATASE; RETINOBLASTOMA PROTEIN; S PHASE KINASE ASSOCIATED PROTEIN 2; TRANSCRIPTION FACTOR E2F1;

CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL FATE; CELL GROWTH; CELL MATURATION; DNA DAMAGE; DNA REPLICATION; ENZYME ACTIVATION; ENZYME ACTIVITY; INTERPHASE; MAMMAL CELL; MEIOSIS; MICROFLUIDICS; MITOSIS; NONHUMAN; OOCYTE MATURATION; PHYSIOLOGY; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RESTRICTION SITE; REVIEW; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SINGLE CELL ANALYSIS; TIME LAPSE IMAGING; TRANSCRIPTION INITIATION;

EUKARYOTA; MAMMALIA; METAZOA; SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

ANIMALS; CELL CYCLE CHECKPOINTS; CONSERVED SEQUENCE; EVOLUTION, MOLECULAR; G1 PHASE; S PHASE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SINGLE-CELL ANALYSIS; TIME FACTORS;

EID: 84887622707     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2013.07.010     Document Type: Review

References (67)

1. Hartwell L.H., Culotti J., Reid B. Genetic control of the cell-division cycle in yeast. I. Detection of mutants. Proc Natl Acad Sci U S A 1970, 66:352-359.
2. Hartwell L.H., Culotti J., Pringle J.R., Reid B.J. Genetic control of the cell division cycle in yeast. Science 1974, 183:46-51.
3. Morgan D.O. The Cell Cycle: Principles of Control 2007, Sunderland/New Science Press, London/MA.
4. Pardee A.B. A restriction point for control of normal animal cell proliferation. Proc Natl Acad Sci U S A 1974, 71:1286-1290.
5. Zetterberg A., Larsson O. Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells. Proc Natl Acad Sci U S A 1985, 82:5365-5369.
6. Foster D.A., Yellen P., Xu L., Saqcena M. Regulation of G1 Cell cycle progression: distinguishing the restriction point from a nutrient-sensing cell growth checkpoint(s). Genes Cancer 2010, 1:1124-1131.
7. Cross F.R., Buchler N.E., Skotheim J.M. Evolution of networks and sequences in eukaryotic cell cycle control. Philos Trans R Soc Lond B Biol Sci 2011, 366:3532-3544.
8. Pavletich N.P. Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors. J Mol Biol 1999, 287:821-828.
9. Koivomagi M., Valk E., Venta R., Iofik A., Lepiku M., Balog E.R., Rubin S.M., Morgan D.O., Loog M. Cascades of multisite phosphorylation control Sic1 destruction at the onset of S phase. Nature 2011, 480:128-131.
10. Johnston G.C., Pringle J.R., Hartwell L.H. Coordination of growth with cell division in the yeast Saccharomyces cerevisiae. Exp Cell Res 1977, 105:79-98.
11. Turner J.J., Ewald J.C., Skotheim J.M. Cell size control in yeast. Curr Biol 2012, 22:R350-R359.
12. Di Talia S., Wang H., Skotheim J.M., Rosebrock A.P., Futcher B., Cross F.R. Daughter-specific transcription factors regulate cell size control in budding yeast. PLoS Biol 2009, 7:e1000221.
13. Wang H., Carey L.B., Cai Y., Wijnen H., Futcher B. Recruitment of Cln3 cyclin to promoters controls cell cycle entry via histone deacetylase and other targets. PLoS Biol 2009, 7:e1000189.
14. Shi L., Tu B.P. Acetyl-CoA induces transcription of the key G1 cyclin CLN3 to promote entry into the cell division cycle in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 2013, 110:7318-7323.
15. Schneider B.L., Zhang J., Markwardt J., Tokiwa G., Volpe T., Honey S., Futcher B. Growth rate and cell size modulate the synthesis of, and requirement for, G1-phase cyclins at start. Mol Cell Biol 2004, 24:10802-10813.
16. Nasmyth K. Control of the yeast cell cycle by the Cdc28 protein kinase. Curr Opin Cell Biol 1993, 5:166-179.
17. Costanzo M., Nishikawa J.L., Tang X., Millman J.S., Schub O., Breitkreuz K., Dewar D., Rupes I., Andrews B., Tyers M. CDK activity antagonizes Whi5, an inhibitor of G1/S transcription in yeast. Cell 2004, 117:899-913.
18. de Bruin R.A., McDonald W.H., Kalashnikova T.I., Yates J., Wittenberg C. Cln3 activates G1-specific transcription via phosphorylation of the SBF bound repressor Whi5. Cell 2004, 117:887-898.
19. Ferrezuelo F., Colomina N., Futcher B., Aldea M. The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle. Genome Biol 2010, 11:R67.
20. Skotheim J.M., Di Talia S., Siggia E.D., Cross F.R. Positive feedback of G1 cyclins ensures coherent cell cycle entry. Nature 2008, 454:291-296.
21. Travesa A., Kuo D., de Bruin R.A., Kalashnikova T.I., Guaderrama M., Thai K., Aslanian A., Smolka M.B., Yates J.R., Ideker T., et al. DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1. EMBO J 2012, 31:1811-1822.
22. Bastos de Oliveira F.M., Harris M.R., Brazauskas P., de Bruin R.A., Smolka M.B. Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes. EMBO J 2012, 31:1798-1810.
23. Harris M.R., Lee D., Farmer S., Lowndes N.F., de Bruin R.A. Binding specificity of the g1/s transcriptional regulators in budding yeast. PLoS ONE 2013, 8:e61059.
24. Leung J.Y., Ehmann G.L., Giangrande P.H., Nevins J.R. A role for Myc in facilitating transcription activation by E2F1. Oncogene 2008, 27:4172-4179.
25. Cobrinik D. Pocket proteins and cell cycle control. Oncogene 2005, 24:2796-2809.
26. Weinberg R.A. The retinoblastoma protein and cell cycle control. Cell 1995, 81:323-330.
27. Brehm A., Miska E.A., McCance D.J., Reid J.L., Bannister A.J., Kouzarides T. Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature 1998, 391:597-601.
28. Satyanarayana A., Kaldis P. Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms. Oncogene 2009, 28:2925-2939.
29. Charvin G., Oikonomou C., Siggia E.D., Cross F.R. Origin of irreversibility of cell cycle start in budding yeast. PLoS Biol 2010, 8:e1000284.
30. Yao G., Lee T.J., Mori S., Nevins J.R., You L. A bistable Rb-E2F switch underlies the restriction point. Nat Cell Biol 2008, 10:476-482.
31. Yao G., Tan C., West M., Nevins J.R., You L. Origin of bistability underlying mammalian cell cycle entry. Mol Syst Biol 2011, 7:485.
32. Tyson J.J., Csikasz-Nagy A., Novak B. The dynamics of cell cycle regulation. Bioessays 2002, 24:1095-1109.
33. Justman Q.A., Serber Z., Ferrell J.E., El-Samad H., Shokat K.M. Tuning the activation threshold of a kinase network by nested feedback loops. Science 2009, 324:509-512.
34. Ferrell J.E., Machleder E.M. The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes. Science 1998, 280:895-898.
35. Ferrell J.E., Xiong W. Bistability in cell signaling: how to make continuous processes discontinuous, and reversible processes irreversible. Chaos 2001, 11:227-236.
36. Brandman O., Ferrell J.E., Li R., Meyer T. Interlinked fast and slow positive feedback loops drive reliable cell decisions. Science 2005, 310:496-498.
37. Novak B., Tyson J.J., Gyorffy B., Csikasz-Nagy A. Irreversible cell-cycle transitions are due to systems-level feedback. Nat Cell Biol 2007, 9:724-728.
38. Buchler N.E., Cross F.R. Protein sequestration generates a flexible ultrasensitive response in a genetic network. Mol Syst Biol 2009, 5:272.
39. Sha W., Moore J., Chen K., Lassaletta A.D., Yi C.S., Tyson J.J., Sible J.C. Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts. Proc Natl Acad Sci U S A 2003, 100:975-980.
40. Charvin G., Cross F.R., Siggia E.D. A microfluidic device for temporally controlled gene expression and long-term fluorescent imaging in unperturbed dividing yeast cells. PLoS ONE 2008, 3:e1468.
41. Ferrell J.E. Simple rules for complex processes: new lessons from the budding yeast cell cycle. Mol Cell 2011, 43:497-500.
42. Doncic A., Falleur-Fettig M., Skotheim J.M. Distinct interactions select and maintain a specific cell fate. Mol Cell 2011, 43:528-539.
43. Gomez-Sjoberg R., Leyrat A.A., Pirone D.M., Chen C.S., Quake S.R. Versatile, fully automated, microfluidic cell culture system. Anal Chem 2007, 79:8557-8563.
44. Zwang Y., Sas-Chen A., Drier Y., Shay T., Avraham R., Lauriola M., Shema E., Lidor-Nili E., Jacob-Hirsch J., Amariglio N., et al. Two phases of mitogenic signaling unveil roles for p53 and EGR1 in elimination of inconsistent growth signals. Mol Cell 2011, 42:524-535.
45. Hitomi M., Yang K., Guo Y., Fretthold J., Harwalkar J. Stacey DW: p27Kip1 and cyclin dependent kinase 2 regulate passage through the restriction point. Cell Cycle 2006, 5:2281-2289.
46. Johnson D.G., Ohtani K., Nevins J.R. Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev 1994, 8:1514-1525.
47. Merrick K.A., Wohlbold L., Zhang C., Allen J.J., Horiuchi D., Huskey N.E., Goga A., Shokat K.M., Fisher R.P. Switching Cdk2 on or off with small molecules to reveal requirements in human cell proliferation. Mol Cell 2011, 42:624-636.
48. Yung Y., Walker J.L., Roberts J.M., Assoian R.K. A Skp2 autoinduction loop and restriction point control. J Cell Biol 2007, 178:741-747.
49. Coats S., Flanagan W.M., Nourse J., Roberts J.M. Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle. Science 1996, 272:877-880.
50. Sherr C.J., Roberts J.M. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 1999, 13:1501-1512.
51. Larsson O., Zetterberg A. Existence of a commitment program for mitosis in early G1 in tumour cells. Cell Prolif 1995, 28:33-43.
52. Martinsson H.S., Starborg M., Erlandsson F., Zetterberg A. Single cell analysis of G1 check points-the relationship between the restriction point and phosphorylation of pRb. Exp Cell Res 2005, 305:383-391.
53. Pardee A.B. G1 events and regulation of cell proliferation. Science 1989, 246:603-608.
54. Zetterberg A., Larsson O. Coordination between cell growth and cell cycle transit in animal cells. Cold Spring Harb Symp Quant Biol 1991, 56:137-147.
55. Zhang Q., Austin R.H. Applications of microfluidics in stem cell biology. Bionanoscience 2012, 2:277-286.
56. Fluckiger A.C., Marcy G., Marchand M., Negre D., Cosset F.L., Mitalipov S., Wolf D., Savatier P., Dehay C. Cell cycle features of primate embryonic stem cells. Stem Cells 2006, 24:547-556.
57. Becker K.A., Ghule P.N., Therrien J.A., Lian J.B., Stein J.L., van Wijnen A.J., Stein G.S. Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase. J Cell Physiol 2006, 209:883-893.
58. White J., Stead E., Faast R., Conn S., Cartwright P., Dalton S. Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation. Mol Biol Cell 2005, 16:2018-2027.
59. Thomson M., Liu S.J., Zou L.N., Smith Z., Meissner A., Ramanathan S. Pluripotency factors in embryonic stem cells regulate differentiation into germ layers. Cell 2011, 145:875-889.
60. Eser U., Falleur-Fettig M., Johnson A., Skotheim J.M. Commitment to a cellular transition precedes genome-wide transcriptional change. Mol Cell 2011, 43:515-527.
61. de Bruin R.A., Kalashnikova T.I., Chahwan C., McDonald W.H., Wohlschlegel J., Yates J., Russell P., Wittenberg C. Constraining G1-specific transcription to late G1 phase: the MBF-associated corepressor Nrm1 acts via negative feedback. Mol Cell 2006, 23:483-496.
62. Purvis J.E., Lahav G. Encoding and decoding cellular information through signaling dynamics. Cell 2013, 152:945-956.
63. Purvis J.E., Karhohs K.W., Mock C., Batchelor E., Loewer A. Lahav G: p53 dynamics control cell fate. Science 2012, 336:1440-1444.
64. Albeck J.G., Mills G.B., Brugge J.S. Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals. Mol Cell 2012, 49:249-261.
65. Doncic A., Skotheim J.M. Feedforward regulation ensures stability and rapid reversibility of a cellular state. Mol Cell 2013, 50:856-868.
66. Wainwright L.J., Lasorella A., Iavarone A. Distinct mechanisms of cell cycle arrest control the decision between differentiation and senescence in human neuroblastoma cells. Proc Natl Acad Sci U S A 2001, 98:9396-9400.
67. Denicourt C., Dowdy S.F. Cip/Kip proteins: more than just CDKs inhibitors. Genes Dev 2004, 18:851-855.