-
1
-
-
0142116249
-
Cdk2 knockout mice are viable
-
C. Berthet, E. Aleem, V. Coppola, L. Tessarollo, and P. Kaldis Cdk2 knockout mice are viable Curr. Biol. 13 2003 1775 1785
-
(2003)
Curr. Biol.
, vol.13
, pp. 1775-1785
-
-
Berthet, C.1
Aleem, E.2
Coppola, V.3
Tessarollo, L.4
Kaldis, P.5
-
4
-
-
0037325853
-
Deregulated degradation of the cdk inhibitor p27 and malignant transformation
-
J. Bloom, and M. Pagano Deregulated degradation of the cdk inhibitor p27 and malignant transformation Semin. Cancer Biol. 13 2003 41 47
-
(2003)
Semin. Cancer Biol.
, vol.13
, pp. 41-47
-
-
Bloom, J.1
Pagano, M.2
-
5
-
-
0029097759
-
Radiation-induced cell cycle arrest compromised by p21 deficiency
-
J. Brugarolas, C. Chandrasekaran, J.I. Gordon, D. Beach, T. Jacks, and G.J. Hannon Radiation-induced cell cycle arrest compromised by p21 deficiency Nature 377 1995 552 557
-
(1995)
Nature
, vol.377
, pp. 552-557
-
-
Brugarolas, J.1
Chandrasekaran, C.2
Gordon, J.I.3
Beach, D.4
Jacks, T.5
Hannon, G.J.6
-
6
-
-
0032556952
-
P21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells
-
C. Cayrol, M. Knibiehler, and B. Ducommun p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells Oncogene 16 1998 311 320
-
(1998)
Oncogene
, vol.16
, pp. 311-320
-
-
Cayrol, C.1
Knibiehler, M.2
Ducommun, B.3
-
7
-
-
0028899480
-
Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA
-
J. Chen, P.K. Jackson, M.W. Kirschner, and A. Dutta Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA Nature 374 1995 386 388
-
(1995)
Nature
, vol.374
, pp. 386-388
-
-
Chen, J.1
Jackson, P.K.2
Kirschner, M.W.3
Dutta, A.4
-
9
-
-
0034698170
-
Kip1
-
Kip1 J. Biol. Chem. 275 2000 21960 21968
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 21960-21968
-
-
Collado, M.1
Medema, R.H.2
Garcia-Cao, I.3
Dubuisson, M.L.4
Barradas, M.5
Glassford, J.6
Rivas, C.7
Burgering, B.M.8
Serrano, M.9
Lam, E.W.10
-
11
-
-
1942434712
-
Cip/Kip proteins: More than just CDKs inhibitors
-
C. Denicourt, and S.F. Dowdy Cip/Kip proteins: More than just CDKs inhibitors Genes Dev. 18 2004 851 855
-
(2004)
Genes Dev.
, vol.18
, pp. 851-855
-
-
Denicourt, C.1
Dowdy, S.F.2
-
12
-
-
15844384256
-
Kip1)-deficient mice
-
Kip1)-deficient mice Cell 85 1996 733 744
-
(1996)
Cell
, vol.85
, pp. 733-744
-
-
Fero, M.L.1
Rivkin, M.2
Tasch, M.3
Porter, P.4
Carow, C.E.5
Firpo, E.6
Polyak, K.7
Tsai, L.H.8
Broudy, V.9
Perlmutter, R.M.10
-
13
-
-
0032511848
-
The murine gene p27Kip1 is haplo-insufficient for tumour suppression
-
M.L. Fero, E. Randel, K.E. Gurley, J.M. Roberts, and C.J. Kemp The murine gene p27Kip1 is haplo-insufficient for tumour suppression Nature 396 1998 177 180
-
(1998)
Nature
, vol.396
, pp. 177-180
-
-
Fero, M.L.1
Randel, E.2
Gurley, K.E.3
Roberts, J.M.4
Kemp, C.J.5
-
14
-
-
0029058587
-
Inhibition of cyclin-dependent kinases by p21
-
J.W. Harper, S.J. Elledge, K. Keyomarsi, B. Dynlacht, L.H. Tsai, P. Zhang, S. Dobrowolski, C. Bai, L. Connell-Crowley, and E. Swindell Inhibition of cyclin-dependent kinases by p21 Mol. Biol. Cell 6 1995 387 400
-
(1995)
Mol. Biol. Cell
, vol.6
, pp. 387-400
-
-
Harper, J.W.1
Elledge, S.J.2
Keyomarsi, K.3
Dynlacht, B.4
Tsai, L.H.5
Zhang, P.6
Dobrowolski, S.7
Bai, C.8
Connell-Crowley, L.9
Swindell, E.10
-
15
-
-
15844415946
-
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1)
-
H. Kiyokawa, R.D. Kineman, K.O. Manova-Todorova, V.C. Soares, E.S. Hoffman, M. Ono, D. Khanam, A.C. Hayday, L.A. Frohman, and A. Koff Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1) Cell 85 1996 721 732
-
(1996)
Cell
, vol.85
, pp. 721-732
-
-
Kiyokawa, H.1
Kineman, R.D.2
Manova-Todorova, K.O.3
Soares, V.C.4
Hoffman, E.S.5
Ono, M.6
Khanam, D.7
Hayday, A.C.8
Frohman, L.A.9
Koff, A.10
-
16
-
-
4444307411
-
Mouse development and cell proliferation in the absence of d-cyclins
-
K. Kozar, M.A. Ciemerych, V.I. Rebel, H. Shigematsu, A. Zagozdzon, E. Sicinska, Y. Geng, Q. Yu, S. Bhattacharya, and R.T. Bronson Mouse development and cell proliferation in the absence of d-cyclins Cell 118 2004 477 491
-
(2004)
Cell
, vol.118
, pp. 477-491
-
-
Kozar, K.1
Ciemerych, M.A.2
Rebel, V.I.3
Shigematsu, H.4
Zagozdzon, A.5
Sicinska, E.6
Geng, Y.7
Yu, Q.8
Bhattacharya, S.9
Bronson, R.T.10
-
17
-
-
6844222853
-
Identification of cdk2 binding sites on the p27Kip1 cyclin-dependent kinase inhibitor
-
T.K. Kwon, and A.A. Nordin Identification of cdk2 binding sites on the p27Kip1 cyclin-dependent kinase inhibitor Oncogene 16 1998 755 762
-
(1998)
Oncogene
, vol.16
, pp. 755-762
-
-
Kwon, T.K.1
Nordin, A.A.2
-
18
-
-
0030973878
-
New functional activities for the p21 family of CDK inhibitors
-
J. LaBaer, M.D. Garrett, L.F. Stevenson, J.M. Slingerland, C. Sandhu, H.S. Chou, A. Fattaey, and E. Harlow New functional activities for the p21 family of CDK inhibitors Genes Dev. 11 1997 847 862
-
(1997)
Genes Dev.
, vol.11
, pp. 847-862
-
-
Labaer, J.1
Garrett, M.D.2
Stevenson, L.F.3
Slingerland, J.M.4
Sandhu, C.5
Chou, H.S.6
Fattaey, A.7
Harlow, E.8
-
19
-
-
0028074603
-
Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair
-
R. Li, S. Waga, G.J. Hannon, D. Beach, and B. Stillman Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair Nature 371 1994 534 537
-
(1994)
Nature
, vol.371
, pp. 534-537
-
-
Li, R.1
Waga, S.2
Hannon, G.J.3
Beach, D.4
Stillman, B.5
-
20
-
-
0029928180
-
Analysis of wild-type and mutant p21WAF-1 gene activities
-
J. Lin, C. Reichner, X. Wu, and A.J. Levine Analysis of wild-type and mutant p21WAF-1 gene activities Mol. Cell. Biol. 16 1996 1786 1793
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1786-1793
-
-
Lin, J.1
Reichner, C.2
Wu, X.3
Levine, A.J.4
-
21
-
-
9244224723
-
Intrinsic tumour suppression
-
S.W. Lowe, E. Cepero, and G. Evan Intrinsic tumour suppression Nature 432 2004 307 315
-
(2004)
Nature
, vol.432
, pp. 307-315
-
-
Lowe, S.W.1
Cepero, E.2
Evan, G.3
-
23
-
-
0642378446
-
Cell cycle deregulation: A common motif in cancer
-
M. Malumbres, and A. Carnero Cell cycle deregulation: A common motif in cancer Prog. Cell Cycle Res. 5 2003 5 18
-
(2003)
Prog. Cell Cycle Res.
, vol.5
, pp. 5-18
-
-
Malumbres, M.1
Carnero, A.2
-
24
-
-
4444247138
-
Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6
-
M. Malumbres, R. Sotillo, D. Santamaria, J. Galan, A. Cerezo, S. Ortega, P. Dubus, and M. Barbacid Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6 Cell 118 2004 493 504
-
(2004)
Cell
, vol.118
, pp. 493-504
-
-
Malumbres, M.1
Sotillo, R.2
Santamaria, D.3
Galan, J.4
Cerezo, A.5
Ortega, S.6
Dubus, P.7
Barbacid, M.8
-
26
-
-
0032410285
-
Cip/Kip cyclin-dependent kinase inhibitors: Brakes of the cell cycle engine during development
-
K. Nakayama, and K. Nakayama Cip/Kip cyclin-dependent kinase inhibitors: Brakes of the cell cycle engine during development Bioessays 20 1998 1020 1029
-
(1998)
Bioessays
, vol.20
, pp. 1020-1029
-
-
Nakayama, K.1
Nakayama, K.2
-
27
-
-
0030010591
-
Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
-
Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors Cell 85 1996 707 720
-
(1996)
Cell
, vol.85
, pp. 707-720
-
-
Nakayama, K.1
Ishida, N.2
Shirane, M.3
Inomata, A.4
Inoue, T.5
Shishido, N.6
Horii, I.7
Loh, D.Y.8
Nakayama, K.9
-
28
-
-
2342650733
-
Skp2-mediated degradation of p27 regulates progression into mitosis
-
K. Nakayama, H. Nagahama, Y.A. Minamishima, S. Miyake, N. Ishida, S. Hatakeyama, M. Kitagawa, S. Iemura, T. Natsume, and K.I. Nakayama Skp2-mediated degradation of p27 regulates progression into mitosis Dev. Cell 6 2004 661 672
-
(2004)
Dev. Cell
, vol.6
, pp. 661-672
-
-
Nakayama, K.1
Nagahama, H.2
Minamishima, Y.A.3
Miyake, S.4
Ishida, N.5
Hatakeyama, S.6
Kitagawa, M.7
Iemura, S.8
Natsume, T.9
Nakayama, K.I.10
-
29
-
-
0041854279
-
Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice
-
S. Ortega, I. Prieto, J. Odajima, A. Martín, P. Dubus, R. Sotillo, J.L. Barbero, M. Malumbres, and M. Barbacid Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice Nat. Genet. 35 2003 25 31
-
(2003)
Nat. Genet.
, vol.35
, pp. 25-31
-
-
Ortega, S.1
Prieto, I.2
Odajima, J.3
Martín, A.4
Dubus, P.5
Sotillo, R.6
Barbero, J.L.7
Malumbres, M.8
Barbacid, M.9
-
30
-
-
2442515980
-
Control of DNA synthesis and mitosis by the Skp2-p27-Cdk1/2 axis
-
M. Pagano Control of DNA synthesis and mitosis by the Skp2-p27-Cdk1/2 axis Mol. Cell 14 2004 414 416
-
(2004)
Mol. Cell
, vol.14
, pp. 414-416
-
-
Pagano, M.1
-
31
-
-
0242551536
-
Ratchets and clocks: The cell cycle, ubiquitylation and protein turnover
-
S.I. Reed Ratchets and clocks: The cell cycle, ubiquitylation and protein turnover Nat. Rev. Mol. Cell Biol. 4 2003 855 864
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 855-864
-
-
Reed, S.I.1
-
32
-
-
1942421702
-
Cyclin C/Cdk3 promotes Rb-dependent G0 exit
-
S. Ren, and B.J. Rollins Cyclin C/Cdk3 promotes Rb-dependent G0 exit Cell 117 2004 239 251
-
(2004)
Cell
, vol.117
, pp. 239-251
-
-
Ren, S.1
Rollins, B.J.2
-
33
-
-
0033564697
-
Cdk inhibitors: Positive and negative regulators of G1-phase progression
-
C.J. Sherr, and J.M. Roberts Cdk inhibitors: Positive and negative regulators of G1-phase progression Genes Dev. 13 1999 1501 1512
-
(1999)
Genes Dev.
, vol.13
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
34
-
-
0035803395
-
Wide spectrum of tumors in knock in mice carrying a Cdk4 protein insensitive to INK4 inhibitors
-
S. Sotillo, P. Dubus, J. Martin, E. de la Cueva, S. Ortega, M. Malumbres, and M. Barbacid Wide spectrum of tumors in knock in mice carrying a Cdk4 protein insensitive to INK4 inhibitors EMBO J. 20 2001 6637 6647
-
(2001)
EMBO J.
, vol.20
, pp. 6637-6647
-
-
Sotillo, S.1
Dubus, P.2
Martin, J.3
De La Cueva, E.4
Ortega, S.5
Malumbres, M.6
Barbacid, M.7
-
35
-
-
0028363519
-
P27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21
-
H. Toyoshima, and T. Hunter p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21 Cell 78 1994 67 74
-
(1994)
Cell
, vol.78
, pp. 67-74
-
-
Toyoshima, H.1
Hunter, T.2
-
36
-
-
11844293427
-
P53 and prognosis: New insights and further complexity
-
K.H. Vousden, and C. Prives P53 and prognosis: New insights and further complexity Cell 120 2005 7 10
-
(2005)
Cell
, vol.120
, pp. 7-10
-
-
Vousden, K.H.1
Prives, C.2
-
37
-
-
0028352434
-
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
-
S. Waga, G.J. Hannon, D. Beach, and B. Stillman The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA Nature 369 1994 574 578
-
(1994)
Nature
, vol.369
, pp. 574-578
-
-
Waga, S.1
Hannon, G.J.2
Beach, D.3
Stillman, B.4
-
38
-
-
0035852699
-
A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene
-
X. Ye, C. Zhu, and J.W. Harper A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene Proc. Natl. Acad. Sci. USA 98 2001 1682 1686
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 1682-1686
-
-
Ye, X.1
Zhu, C.2
Harper, J.W.3
|