메뉴 건너뛰기




Volumn 5, Issue JAN, 2016, Pages

Dysregulated expression of glycolipids in tumor cells: From Negative Modulator of Anti-tumor Immunity to Promising Targets for Developing Therapeutic Agents

Author keywords

Antibodies; Cancer; Gangliosides; Glycolipids; Immunotherapy; Immunotoxin

Indexed keywords

GAMMA INTERFERON; GLYCOLIPID; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 6; RACOTUMOMAB;

EID: 84958175805     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2015.00300     Document Type: Short Survey
Times cited : (35)

References (153)
  • 1
    • 77956552951 scopus 로고    scopus 로고
    • Neobiosynthesis of glycosphingolipids by plasma membrane-associated glycosyltransferases
    • Crespo PM, Demichelis VT, Daniotti JL. Neobiosynthesis of glycosphingolipids by plasma membrane-associated glycosyltransferases. J Biol Chem (2010) 285(38):29179-90. doi: 10.1074/jbc. M110.123422
    • (2010) J Biol Chem , vol.285 , Issue.38 , pp. 29179-29190
    • Crespo, P.M.1    Demichelis, V.T.2    Daniotti, J.L.3
  • 2
    • 80052405332 scopus 로고    scopus 로고
    • Trans-activity of plasma membrane-associated ganglioside sialyltransferase in mammalian cells
    • Vilcaes AA, Demichelis VT, Daniotti JL. Trans-activity of plasma membrane-associated ganglioside sialyltransferase in mammalian cells. J Biol Chem (2011) 286(36):31437-46. doi:10.1074/jbc. M111.257196
    • (2011) J Biol Chem , vol.286 , Issue.36 , pp. 31437-31446
    • Vilcaes, A.A.1    Demichelis, V.T.2    Daniotti, J.L.3
  • 3
    • 23844431674 scopus 로고    scopus 로고
    • Changes in the glycolipid composition and characteristic activation of GM3 synthase in the thymus of mouse after administration of dexamethasone
    • Iwamori M, Iwamori Y. Changes in the glycolipid composition and characteristic activation of GM3 synthase in the thymus of mouse after administration of dexamethasone. Glycoconj J (2005) 22(3):119-26. doi:10.1007/s10719-005-0363-9
    • (2005) Glycoconj J , vol.22 , Issue.3 , pp. 119-126
    • Iwamori, M.1    Iwamori, Y.2
  • 4
    • 0016162085 scopus 로고
    • Mechanism of cell contact-dependent glycolipid synthesis: further studies with glycolipid-glass complex
    • Yogeeswaran G, Laine RA, Hakomori S. Mechanism of cell contact-dependent glycolipid synthesis: further studies with glycolipid-glass complex. Biochem Biophys Res Commun (1974) 59(2):591-9. doi:10.1016/S0006-291X(74)80021-5
    • (1974) Biochem Biophys Res Commun , vol.59 , Issue.2 , pp. 591-599
    • Yogeeswaran, G.1    Laine, R.A.2    Hakomori, S.3
  • 5
    • 79959586493 scopus 로고    scopus 로고
    • Metabolic pathways and intracellular trafficking of gangliosides
    • Daniotti JL, Iglesias-Bartolome R. Metabolic pathways and intracellular trafficking of gangliosides. IUBMB Life (2011) 63(7):513-20. doi:10.1002/iub.477
    • (2011) IUBMB Life , vol.63 , Issue.7 , pp. 513-520
    • Daniotti, J.L.1    Iglesias-Bartolome, R.2
  • 6
    • 0347611095 scopus 로고    scopus 로고
    • Molecular machinery for non-vesicular trafficking of ceramide
    • Hanada K, Kumagai K, Yasuda S, Miura Y, Kawano M, Fukasawa M, et al. Molecular machinery for non-vesicular trafficking of ceramide. Nature (2003) 426(6968):803-9. doi:10.1038/nature02188
    • (2003) Nature , vol.426 , Issue.6968 , pp. 803-809
    • Hanada, K.1    Kumagai, K.2    Yasuda, S.3    Miura, Y.4    Kawano, M.5    Fukasawa, M.6
  • 7
    • 79954988198 scopus 로고    scopus 로고
    • Cellular and molecular biology of glycosphingolipid glycosylation
    • Maccioni HJ, Quiroga R, Ferrari ML. Cellular and molecular biology of glycosphingolipid glycosylation. J Neurochem (2011) 117(4):589-602. doi:10.1111/j.1471-4159.2011.07232.x
    • (2011) J Neurochem , vol.117 , Issue.4 , pp. 589-602
    • Maccioni, H.J.1    Quiroga, R.2    Ferrari, M.L.3
  • 8
    • 80054079107 scopus 로고    scopus 로고
    • Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics
    • Merrill AH Jr. Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics. Chem Rev (2011) 111(10):6387-422. doi:10.1021/cr2002917
    • (2011) Chem Rev , vol.111 , Issue.10 , pp. 6387-6422
    • Merrill, A.H.1
  • 9
    • 3543085572 scopus 로고    scopus 로고
    • Ganglioside/glycosphingolipid turnover: new concepts
    • Tettamanti G. Ganglioside/glycosphingolipid turnover: new concepts. Glycoconj J (2004) 20(5):301-17. doi:10.1023/B:GLYC.0000033627.02765.cc
    • (2004) Glycoconj J , vol.20 , Issue.5 , pp. 301-317
    • Tettamanti, G.1
  • 10
    • 26844487442 scopus 로고    scopus 로고
    • Identification of plasma membrane associated mature beta-hexosaminidase A, active towards GM2 ganglioside, in human fibroblasts
    • Mencarelli S, Cavalieri C, Magini A, Tancini B, Basso L, Lemansky P, et al. Identification of plasma membrane associated mature beta-hexosaminidase A, active towards GM2 ganglioside, in human fibroblasts. FEBS Lett (2005) 579(25):5501-6. doi:10.1016/j.febslet.2005.08.081
    • (2005) FEBS Lett , vol.579 , Issue.25 , pp. 5501-5506
    • Mencarelli, S.1    Cavalieri, C.2    Magini, A.3    Tancini, B.4    Basso, L.5    Lemansky, P.6
  • 11
    • 84861413498 scopus 로고    scopus 로고
    • Mammalian sialidases: physiological and pathological roles in cellular functions
    • Miyagi T, Yamaguchi K. Mammalian sialidases: physiological and pathological roles in cellular functions. Glycobiology (2012) 22(7):880-96. doi:10.1093/glycob/cws057
    • (2012) Glycobiology , vol.22 , Issue.7 , pp. 880-896
    • Miyagi, T.1    Yamaguchi, K.2
  • 12
    • 38449090335 scopus 로고    scopus 로고
    • Modulation of cell functions by glycosphingolipid metabolic remodeling in the plasma membrane
    • Prinetti A, Chigorno V, Mauri L, Loberto N, Sonnino S. Modulation of cell functions by glycosphingolipid metabolic remodeling in the plasma membrane. J Neurochem (2007) 103:113-25. doi:10.1111/j.1471-4159.2007.04714.x
    • (2007) J Neurochem , vol.103 , pp. 113-125
    • Prinetti, A.1    Chigorno, V.2    Mauri, L.3    Loberto, N.4    Sonnino, S.5
  • 13
    • 84938801354 scopus 로고    scopus 로고
    • Role of plasma-membrane-bound sialidase NEU3 in clathrin-mediated endocytosis
    • Rodriguez-Walker M, Vilcaes AA, Garbarino-Pico E, Daniotti JL. Role of plasma-membrane-bound sialidase NEU3 in clathrin-mediated endocytosis. Biochem J (2015) 470(1):131-44. doi:10.1042/BJ20141550
    • (2015) Biochem J , vol.470 , Issue.1 , pp. 131-144
    • Rodriguez-Walker, M.1    Vilcaes, A.A.2    Garbarino-Pico, E.3    Daniotti, J.L.4
  • 14
    • 77951922837 scopus 로고    scopus 로고
    • Fine tuning of cell functions through remodeling of glycosphingolipids by plasma membrane-associated glycohydrolases
    • Sonnino S, Aureli M, Loberto N, Chigorno V, Prinetti A. Fine tuning of cell functions through remodeling of glycosphingolipids by plasma membrane-associated glycohydrolases. FEBS Lett (2010) 584(9):1914-22. doi:10.1016/j.febslet.2009.11.020
    • (2010) FEBS Lett , vol.584 , Issue.9 , pp. 1914-1922
    • Sonnino, S.1    Aureli, M.2    Loberto, N.3    Chigorno, V.4    Prinetti, A.5
  • 15
    • 84886394870 scopus 로고    scopus 로고
    • Ganglioside biochemistry
    • Kolter T. Ganglioside biochemistry. ISRN Biochem (2012) 2012:506160. doi:10.5402/2012/506160
    • (2012) ISRN Biochem , vol.2012
    • Kolter, T.1
  • 16
    • 77951924919 scopus 로고    scopus 로고
    • Lysosomal degradation of membrane lipids
    • Kolter T, SandhoffK. Lysosomal degradation of membrane lipids. FEBS Lett (2010) 584(9):1700-12. doi:10.1016/j.febslet.2009.10.021
    • (2010) FEBS Lett , vol.584 , Issue.9 , pp. 1700-1712
    • Kolter, T.1    Sandhoff, K.2
  • 17
    • 0037762571 scopus 로고    scopus 로고
    • Biosynthesis and degradation of mammalian glycosphingolipids
    • SandhoffK, Kolter T. Biosynthesis and degradation of mammalian glycosphingolipids. Philos Trans R Soc Lond B Biol Sci (2003) 358(1433):847-61. doi:10.1098/rstb.2003.1265
    • (2003) Philos Trans R Soc Lond B Biol Sci , vol.358 , Issue.1433 , pp. 847-861
    • Sandhoff, K.1    Kolter, T.2
  • 19
    • 0019363342 scopus 로고
    • Glycosphingolipids in cellular interaction, differentiation, and oncogenesis
    • Hakomori S. Glycosphingolipids in cellular interaction, differentiation, and oncogenesis. Annu Rev Biochem (1981) 50:733-64. doi:10.1146/annurev.bi.50.070181.003505
    • (1981) Annu Rev Biochem , vol.50 , pp. 733-764
    • Hakomori, S.1
  • 20
    • 38449104148 scopus 로고    scopus 로고
    • Glycosylation of glycolipids in the Golgi complex
    • Maccioni HJ. Glycosylation of glycolipids in the Golgi complex. J Neurochem (2007) 103:81-90. doi:10.1111/j.1471-4159.2007.04717.x
    • (2007) J Neurochem , vol.103 , pp. 81-90
    • Maccioni, H.J.1
  • 21
    • 0033602111 scopus 로고    scopus 로고
    • Organization of ganglioside synthesis in the Golgi apparatus
    • Maccioni HJ, Daniotti JL, Martina JA. Organization of ganglioside synthesis in the Golgi apparatus. Biochim Biophys Acta (1999) 1437(2):101-18. doi:10.1016/S1388-1981(99)00002-5
    • (1999) Biochim Biophys Acta , vol.1437 , Issue.2 , pp. 101-118
    • Maccioni, H.J.1    Daniotti, J.L.2    Martina, J.A.3
  • 22
    • 33751163743 scopus 로고    scopus 로고
    • In vivo modulation of epidermal growth factor receptor phosphorylation in mice expressing different gangliosides
    • Daniotti JL, Crespo PM, Yamashita T. In vivo modulation of epidermal growth factor receptor phosphorylation in mice expressing different gangliosides. J Cell Biochem (2006) 99(5):1442-51. doi:10.1002/jcb.21034
    • (2006) J Cell Biochem , vol.99 , Issue.5 , pp. 1442-1451
    • Daniotti, J.L.1    Crespo, P.M.2    Yamashita, T.3
  • 23
    • 70349871692 scopus 로고    scopus 로고
    • Gangliosides in cell recognition and membrane protein regulation
    • Lopez PH, Schnaar RL. Gangliosides in cell recognition and membrane protein regulation. Curr Opin Struct Biol (2009) 19(5):549-57. doi:10.1016/j.sbi.2009.06.001
    • (2009) Curr Opin Struct Biol , vol.19 , Issue.5 , pp. 549-557
    • Lopez, P.H.1    Schnaar, R.L.2
  • 24
    • 0038100164 scopus 로고    scopus 로고
    • Glycosphingolipid functions: insights from engineered mouse models
    • Proia RL. Glycosphingolipid functions: insights from engineered mouse models. Philos Trans R Soc Lond B Biol Sci (2003) 358(1433):879-83. doi:10.1098/rstb.2003.1268
    • (2003) Philos Trans R Soc Lond B Biol Sci , vol.358 , Issue.1433 , pp. 879-883
    • Proia, R.L.1
  • 25
    • 40749132024 scopus 로고    scopus 로고
    • Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains
    • Regina Todeschini A, Hakomori SI. Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains. Biochim Biophys Acta (2008) 1780(3):421-33. doi:10.1016/j.bbagen.2007.10.008
    • (2008) Biochim Biophys Acta , vol.1780 , Issue.3 , pp. 421-433
    • Regina Todeschini, A.1    Hakomori, S.I.2
  • 27
    • 32944463464 scopus 로고    scopus 로고
    • Gangliosides of myelosupportive stroma cells are transferred to myeloid progenitors and are required for their survival and proliferation
    • Ziulkoski AL, Andrade CM, Crespo PM, Sisti E, Trindade VM, Daniotti JL, et al. Gangliosides of myelosupportive stroma cells are transferred to myeloid progenitors and are required for their survival and proliferation. Biochem J (2006) 394(Pt 1):1-9. doi:10.1042/BJ20051189
    • (2006) Biochem J , vol.394 , pp. 1-9
    • Ziulkoski, A.L.1    Andrade, C.M.2    Crespo, P.M.3    Sisti, E.4    Trindade, V.M.5    Daniotti, J.L.6
  • 28
    • 0035871076 scopus 로고    scopus 로고
    • Modulation of epidermal growth factor receptor phosphorylation by endogenously expressed gangliosides
    • Zurita AR, Maccioni HJ, Daniotti JL. Modulation of epidermal growth factor receptor phosphorylation by endogenously expressed gangliosides. Biochem J (2001) 355(Pt 2):465-72. doi:10.1042/0264-6021:3550465
    • (2001) Biochem J , vol.355 , pp. 465-472
    • Zurita, A.R.1    Maccioni, H.J.2    Daniotti, J.L.3
  • 29
    • 78649720042 scopus 로고    scopus 로고
    • Molecular mechanisms of pathogenesis in a glycosphingolipid and a glycoprotein storage disease
    • d'Azzo A, Bonten E. Molecular mechanisms of pathogenesis in a glycosphingolipid and a glycoprotein storage disease. Biochem Soc Trans (2010) 38(6):1453-7. doi:10.1042/BST0381453
    • (2010) Biochem Soc Trans , vol.38 , Issue.6 , pp. 1453-1457
    • d'Azzo, A.1    Bonten, E.2
  • 30
    • 33845343984 scopus 로고    scopus 로고
    • Sphingolipid metabolism diseases
    • Kolter T, SandhoffK. Sphingolipid metabolism diseases. Biochim Biophys Acta (2006) 1758(12):2057-79. doi:10.1016/j.bbamem.2006.05.027
    • (2006) Biochim Biophys Acta , vol.1758 , Issue.12 , pp. 2057-2079
    • Kolter, T.1    Sandhoff, K.2
  • 31
    • 84901950458 scopus 로고    scopus 로고
    • Sphingolipid lysosomal storage disorders
    • Platt FM. Sphingolipid lysosomal storage disorders. Nature (2014) 510(7503):68-75. doi:10.1038/nature13476
    • (2014) Nature , vol.510 , Issue.7503 , pp. 68-75
    • Platt, F.M.1
  • 32
    • 84893485192 scopus 로고    scopus 로고
    • Mutations in B4GALNT1 (GM2 synthase) underlie a new disorder of ganglioside biosynthesis
    • Harlalka GV, Lehman A, Chioza B, Baple EL, Maroofian R, Cross H, et al. Mutations in B4GALNT1 (GM2 synthase) underlie a new disorder of ganglioside biosynthesis. Brain (2013) 136(Pt 12):3618-24. doi:10.1093/brain/awt270
    • (2013) Brain , vol.136 , pp. 3618-3624
    • Harlalka, G.V.1    Lehman, A.2    Chioza, B.3    Baple, E.L.4    Maroofian, R.5    Cross, H.6
  • 33
    • 80052722309 scopus 로고    scopus 로고
    • ST3GAL3 mutations impair the development of higher cognitive functions
    • Hu H, Eggers K, Chen W, Garshasbi M, Motazacker MM, Wrogemann K, et al. ST3GAL3 mutations impair the development of higher cognitive functions. Am J Hum Genet (2011) 89(3):407-14. doi:10.1016/j.ajhg.2011.08.008
    • (2011) Am J Hum Genet , vol.89 , Issue.3 , pp. 407-414
    • Hu, H.1    Eggers, K.2    Chen, W.3    Garshasbi, M.4    Motazacker, M.M.5    Wrogemann, K.6
  • 34
    • 14544280429 scopus 로고    scopus 로고
    • Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase
    • Simpson MA, Cross H, Proukakis C, Priestman DA, Neville DC, Reinkensmeier G, et al. Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase. Nat Genet (2004) 36(11):1225-9. doi:10.1038/ng1460
    • (2004) Nat Genet , vol.36 , Issue.11 , pp. 1225-1229
    • Simpson, M.A.1    Cross, H.2    Proukakis, C.3    Priestman, D.A.4    Neville, D.C.5    Reinkensmeier, G.6
  • 35
    • 0017640429 scopus 로고
    • Glycolipid-bound sialic acid in serum: increased levels in mice and humans bearing mammary carcinomas
    • Kloppel TM, Keenan TW, Freeman MJ, Morré DJ. Glycolipid-bound sialic acid in serum: increased levels in mice and humans bearing mammary carcinomas. Proc Natl Acad Sci U S A (1977) 74(7):3011-3. doi:10.1073/pnas.74.7.3011
    • (1977) Proc Natl Acad Sci U S A , vol.74 , Issue.7 , pp. 3011-3013
    • Kloppel, T.M.1    Keenan, T.W.2    Freeman, M.J.3    Morré, D.J.4
  • 36
    • 33646083938 scopus 로고    scopus 로고
    • Shedding and uptake of gangliosides and glycosylphosphatidylinositol-anchored proteins
    • Lauc G, Heffer-Lauc M. Shedding and uptake of gangliosides and glycosylphosphatidylinositol-anchored proteins. Biochim Biophys Acta (2006) 1760(4):584-602. doi:10.1016/j.bbagen.2005.11.014
    • (2006) Biochim Biophys Acta , vol.1760 , Issue.4 , pp. 584-602
    • Lauc, G.1    Heffer-Lauc, M.2
  • 37
    • 0029863643 scopus 로고    scopus 로고
    • Intercellular transfer of shed tumor cell gangliosides
    • Olshefski R, Ladisch S. Intercellular transfer of shed tumor cell gangliosides. FEBS Lett (1996) 386(1):11-4. doi:10.1016/0014-5793(96)00392-4
    • (1996) FEBS Lett , vol.386 , Issue.1 , pp. 11-14
    • Olshefski, R.1    Ladisch, S.2
  • 38
    • 0018267971 scopus 로고
    • Alteration of gangliosides in plasma and red cells of humans bearing melanoma tumors
    • Portoukalian J, Zwingelstein G, Abdul-Malak N, Doré JF. Alteration of gangliosides in plasma and red cells of humans bearing melanoma tumors. Biochem Biophys Res Commun (1978) 85(3):916-20. doi:10.1016/0006-291X(78)90630-7
    • (1978) Biochem Biophys Res Commun , vol.85 , Issue.3 , pp. 916-920
    • Portoukalian, J.1    Zwingelstein, G.2    Abdul-Malak, N.3    Doré, J.F.4
  • 39
    • 84969431581 scopus 로고    scopus 로고
    • Immune response modulation by tumor-secreted glycosphingolipids
    • Lardone RD, Cely I, Sieling PA, Lee DJ. Immune response modulation by tumor-secreted glycosphingolipids. J Glycobiol (2014) 3(1):107. doi:10.4172/2168-958X.1000107
    • (2014) J Glycobiol , vol.3 , Issue.1 , pp. 107
    • Lardone, R.D.1    Cely, I.2    Sieling, P.A.3    Lee, D.J.4
  • 40
    • 34047220868 scopus 로고    scopus 로고
    • Cancer immunoediting from immune surveillance to immune escape
    • Kim R, Emi M, Tanabe K. Cancer immunoediting from immune surveillance to immune escape. Immunology (2007) 121(1):1-14. doi:10.1111/j.1365-2567.2007.02587.x
    • (2007) Immunology , vol.121 , Issue.1 , pp. 1-14
    • Kim, R.1    Emi, M.2    Tanabe, K.3
  • 41
    • 84930909270 scopus 로고    scopus 로고
    • Cancer intelligence acquired (CIA): tumor glycosylation and sialylation codes dismantling antitumor defense
    • Boligan KF, Mesa C, Fernandez LE, von Gunten S. Cancer intelligence acquired (CIA): tumor glycosylation and sialylation codes dismantling antitumor defense. Cell Mol Life Sci (2015) 72(7):1231-48. doi:10.1007/s00018-014-1799-5
    • (2015) Cell Mol Life Sci , vol.72 , Issue.7 , pp. 1231-1248
    • Boligan, K.F.1    Mesa, C.2    Fernandez, L.E.3    von Gunten, S.4
  • 42
    • 0021048720 scopus 로고
    • Cytotoxic effector cell function at different stages of human monocyte-macrophage maturation
    • Andreesen R, Osterholz J, Bross KJ, Schulz A, Luckenbach GA, Löhr GW. Cytotoxic effector cell function at different stages of human monocyte-macrophage maturation. Cancer Res (1983) 43(12 Pt 1):5931-6.
    • (1983) Cancer Res , vol.43 , Issue.12 , pp. 5931-5936
    • Andreesen, R.1    Osterholz, J.2    Bross, K.J.3    Schulz, A.4    Luckenbach, G.A.5    Löhr, G.W.6
  • 43
    • 33747880652 scopus 로고    scopus 로고
    • Ex vivo-activated human macrophages kill chronic lymphocytic leukemia cells in the presence of rituximab: mechanism of antibody-dependent cellular cytotoxicity and impact of human serum
    • Lefebvre ML, Krause SW, Salcedo M, Nardin A. Ex vivo-activated human macrophages kill chronic lymphocytic leukemia cells in the presence of rituximab: mechanism of antibody-dependent cellular cytotoxicity and impact of human serum. J Immunother (2006) 29(4):388-97. doi:10.1097/01.cji.0000203081.43235.d7
    • (2006) J Immunother , vol.29 , Issue.4 , pp. 388-397
    • Lefebvre, M.L.1    Krause, S.W.2    Salcedo, M.3    Nardin, A.4
  • 44
    • 58749083404 scopus 로고    scopus 로고
    • Macrophages as APC and the dendritic cell myth
    • Hume DA. Macrophages as APC and the dendritic cell myth. J Immunol (2008) 181(9):5829-35. doi:10.4049/jimmunol.181.9.5829
    • (2008) J Immunol , vol.181 , Issue.9 , pp. 5829-5835
    • Hume, D.A.1
  • 46
    • 0032971371 scopus 로고    scopus 로고
    • The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids
    • Porcelli SA, Modlin RL. The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids. Annu Rev Immunol (1999) 17(1):297-329. doi:10.1146/annurev.immunol.17.1.297
    • (1999) Annu Rev Immunol , vol.17 , Issue.1 , pp. 297-329
    • Porcelli, S.A.1    Modlin, R.L.2
  • 47
    • 84885840329 scopus 로고    scopus 로고
    • Immune correlates of melanoma survival in adoptive cell therapy
    • Lee AF, Sieling PA, Lee DJ. Immune correlates of melanoma survival in adoptive cell therapy. Oncoimmunology (2013) 2(2):e22889. doi:10.4161/onci.22889
    • (2013) Oncoimmunology , vol.2 , Issue.2
    • Lee, A.F.1    Sieling, P.A.2    Lee, D.J.3
  • 48
    • 0030603983 scopus 로고    scopus 로고
    • Gangliosides block antigen presentation by human monocytes
    • Heitger A, Ladisch S. Gangliosides block antigen presentation by human monocytes. Biochim Biophys Acta (1996) 1303(2):161-8. doi:10.1016/0005-2760(96)00091-4
    • (1996) Biochim Biophys Acta , vol.1303 , Issue.2 , pp. 161-168
    • Heitger, A.1    Ladisch, S.2
  • 49
    • 0043092307 scopus 로고    scopus 로고
    • Mechanisms of ganglioside inhibition of APC function
    • Caldwell S, Heitger A, Shen W, Liu Y, Taylor B, Ladisch S. Mechanisms of ganglioside inhibition of APC function. J Immunol (2003) 171(4):1676-83. doi:10.4049/jimmunol.171.4.1676
    • (2003) J Immunol , vol.171 , Issue.4 , pp. 1676-1683
    • Caldwell, S.1    Heitger, A.2    Shen, W.3    Liu, Y.4    Taylor, B.5    Ladisch, S.6
  • 52
    • 44449154904 scopus 로고    scopus 로고
    • Inhibition of TLR activation and up-regulation of IL-1R-associated kinase-M expression by exogenous gangliosides
    • Shen W, Stone K, Jales A, Leitenberg D, Ladisch S. Inhibition of TLR activation and up-regulation of IL-1R-associated kinase-M expression by exogenous gangliosides. J Immunol (2008) 180(7):4425-32. doi:10.4049/jimmunol.180.7.4425
    • (2008) J Immunol , vol.180 , Issue.7 , pp. 4425-4432
    • Shen, W.1    Stone, K.2    Jales, A.3    Leitenberg, D.4    Ladisch, S.5
  • 53
    • 84889660927 scopus 로고    scopus 로고
    • Monosialic ganglioside GM3 specifically suppresses the monocyte adhesion to endothelial cells for inflammation
    • Kim SJ, Chung TW, Choi HJ, Jin UH, Ha KT, Lee YC, et al. Monosialic ganglioside GM3 specifically suppresses the monocyte adhesion to endothelial cells for inflammation. Int J Biochem Cell Biol (2014) 46:32-8. doi:10.1016/j.biocel.2013.09.015
    • (2014) Int J Biochem Cell Biol , vol.46 , pp. 32-38
    • Kim, S.J.1    Chung, T.W.2    Choi, H.J.3    Jin, U.H.4    Ha, K.T.5    Lee, Y.C.6
  • 54
    • 84907495445 scopus 로고    scopus 로고
    • Gangliosides drive the tumor infiltration and function of myeloid-derived suppressor cells
    • Wondimu A, Liu Y, Su Y, Bobb D, Ma JS, Chakrabarti L, et al. Gangliosides drive the tumor infiltration and function of myeloid-derived suppressor cells. Cancer Res (2014) 74(19):5449-57. doi:10.1158/0008-5472.CAN-14-0927
    • (2014) Cancer Res , vol.74 , Issue.19 , pp. 5449-5457
    • Wondimu, A.1    Liu, Y.2    Su, Y.3    Bobb, D.4    Ma, J.S.5    Chakrabarti, L.6
  • 55
    • 0036444239 scopus 로고    scopus 로고
    • Gangliosides inhibit the development from monocytes to dendritic cells
    • WölflM, Batten WY, Posovszky C, Bernhard H, Berthold F. Gangliosides inhibit the development from monocytes to dendritic cells. Clin Exp Immunol (2002) 130(3):441-8. doi:10.1046/j.1365-2249.2002.02006.x
    • (2002) Clin Exp Immunol , vol.130 , Issue.3 , pp. 441-448
    • Wölfl, M.1    Batten, W.Y.2    Posovszky, C.3    Bernhard, H.4    Berthold, F.5
  • 56
    • 26844578733 scopus 로고    scopus 로고
    • Modulation of CD4 Th cell differentiation by ganglioside GD1a in vitro
    • Shen W, Falahati R, Stark R, Leitenberg D, Ladisch S. Modulation of CD4 Th cell differentiation by ganglioside GD1a in vitro. J Immunol (2005) 175(8):4927-34. doi:10.4049/jimmunol.175.8.4927
    • (2005) J Immunol , vol.175 , Issue.8 , pp. 4927-4934
    • Shen, W.1    Falahati, R.2    Stark, R.3    Leitenberg, D.4    Ladisch, S.5
  • 57
    • 0037379513 scopus 로고    scopus 로고
    • Gangliosides from human melanoma tumors impair dendritic cell differentiation from monocytes and induce their apoptosis
    • Péguet-Navarro J, Sportouch M, Popa I, Berthier O, Schmitt D, Portoukalian J. Gangliosides from human melanoma tumors impair dendritic cell differentiation from monocytes and induce their apoptosis. J Immunol (2003) 170(7):3488-94. doi:10.4049/jimmunol.170.7.3488
    • (2003) J Immunol , vol.170 , Issue.7 , pp. 3488-3494
    • Péguet-Navarro, J.1    Sportouch, M.2    Popa, I.3    Berthier, O.4    Schmitt, D.5    Portoukalian, J.6
  • 58
    • 65849483467 scopus 로고    scopus 로고
    • Different mechanisms are involved in apoptosis induced by melanoma gangliosides on human monocyte-derived dendritic cells
    • Bennaceur K, Popa I, Chapman JA, Migdal C, Péguet-Navarro J, Touraine JL, et al. Different mechanisms are involved in apoptosis induced by melanoma gangliosides on human monocyte-derived dendritic cells. Glycobiology (2009) 19(6):576-82. doi:10.1093/glycob/cwp015
    • (2009) Glycobiology , vol.19 , Issue.6 , pp. 576-582
    • Bennaceur, K.1    Popa, I.2    Chapman, J.A.3    Migdal, C.4    Péguet-Navarro, J.5    Touraine, J.L.6
  • 59
    • 33745624850 scopus 로고    scopus 로고
    • Melanoma-derived gangliosides impair migratory and antigen-presenting function of human epidermal Langerhans cells and induce their apoptosis
    • Bennaceur K, Popa I, Portoukalian J, Berthier-Vergnes O, Péguet-Navarro J. Melanoma-derived gangliosides impair migratory and antigen-presenting function of human epidermal Langerhans cells and induce their apoptosis. Int Immunol (2006) 18(6):879-86. doi:10.1093/intimm/dxl024
    • (2006) Int Immunol , vol.18 , Issue.6 , pp. 879-886
    • Bennaceur, K.1    Popa, I.2    Portoukalian, J.3    Berthier-Vergnes, O.4    Péguet-Navarro, J.5
  • 60
    • 84897566999 scopus 로고    scopus 로고
    • Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance
    • Jandus C, Boligan KF, Chijioke O, Liu H, Dahlhaus M, Démoulins T, et al. Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. J Clin Invest (2014) 124(4):1810-20. doi:10.1172/JCI65899
    • (2014) J Clin Invest , vol.124 , Issue.4 , pp. 1810-1820
    • Jandus, C.1    Boligan, K.F.2    Chijioke, O.3    Liu, H.4    Dahlhaus, M.5    Démoulins, T.6
  • 61
    • 77957855197 scopus 로고    scopus 로고
    • Ganglioside DSGb5, preferred ligand for Siglec-7, inhibits NK cell cytotoxicity against renal cell carcinoma cells
    • Kawasaki Y, Ito A, Withers DA, Taima T, Kakoi N, Saito S, et al. Ganglioside DSGb5, preferred ligand for Siglec-7, inhibits NK cell cytotoxicity against renal cell carcinoma cells. Glycobiology (2010) 20(11):1373-9. doi:10.1093/glycob/cwq116
    • (2010) Glycobiology , vol.20 , Issue.11 , pp. 1373-1379
    • Kawasaki, Y.1    Ito, A.2    Withers, D.A.3    Taima, T.4    Kakoi, N.5    Saito, S.6
  • 62
    • 0037744803 scopus 로고    scopus 로고
    • Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec-7-dependent and-independent mechanisms
    • Nicoll G, Avril T, Lock K, Furukawa K, Bovin N, Crocker PR. Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec-7-dependent and-independent mechanisms. Eur J Immunol (2003) 33(6):1642-8. doi:10.1002/eji.200323693
    • (2003) Eur J Immunol , vol.33 , Issue.6 , pp. 1642-1648
    • Nicoll, G.1    Avril, T.2    Lock, K.3    Furukawa, K.4    Bovin, N.5    Crocker, P.R.6
  • 63
    • 84864842768 scopus 로고    scopus 로고
    • Molecular identification of GD3 as a suppressor of the innate immune response in ovarian cancer
    • Webb TJ, Li X, Giuntoli RL II, Lopez PH, Heuser C, Schnaar RL, et al. Molecular identification of GD3 as a suppressor of the innate immune response in ovarian cancer. Cancer Res (2012) 72(15):3744-52. doi:10.1158/0008-5472.CAN-11-2695
    • (2012) Cancer Res , vol.72 , Issue.15 , pp. 3744-3752
    • Webb, T.J.1    Li, X.2    Giuntoli, R.L.3    Lopez, P.H.4    Heuser, C.5    Schnaar, R.L.6
  • 64
    • 0037062413 scopus 로고    scopus 로고
    • Inhibition of glycolipid shedding rescues recognition of a CD1+ T cell lymphoma by natural killer T (NKT) cells
    • Sriram V, Cho S, Li P, O'Donnell PW, Dunn C, Hayakawa K, et al. Inhibition of glycolipid shedding rescues recognition of a CD1+ T cell lymphoma by natural killer T (NKT) cells. Proc Natl Acad Sci U S A (2002) 99(12):8197-202. doi:10.1073/pnas.122636199
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.12 , pp. 8197-8202
    • Sriram, V.1    Cho, S.2    Li, P.3    O'Donnell, P.W.4    Dunn, C.5    Hayakawa, K.6
  • 65
    • 0027968524 scopus 로고
    • Differential effects of gangliosides on Ig production and proliferation by human B cells
    • Kimata H, Yoshida A. Differential effects of gangliosides on Ig production and proliferation by human B cells. Blood (1994) 84(4):1193-200.
    • (1994) Blood , vol.84 , Issue.4 , pp. 1193-1200
    • Kimata, H.1    Yoshida, A.2
  • 66
    • 0029937657 scopus 로고    scopus 로고
    • Inhibition of spontaneous immunoglobulin production by ganglioside GM2 in human B cells
    • Kimata H, Yoshida A. Inhibition of spontaneous immunoglobulin production by ganglioside GM2 in human B cells. Clin Immunol Immunopathol (1996) 79(2):197-202. doi:10.1006/clin.1996.0068
    • (1996) Clin Immunol Immunopathol , vol.79 , Issue.2 , pp. 197-202
    • Kimata, H.1    Yoshida, A.2
  • 67
    • 0032589404 scopus 로고    scopus 로고
    • Ganglioside GD1b suppresses immunoglobulin production by human peripheral blood mononuclear cells
    • Kanda N, Tamaki K. Ganglioside GD1b suppresses immunoglobulin production by human peripheral blood mononuclear cells. Exp Hematol (1999) 27(10):1487-93. doi:10.1016/S0301-472X(99)00093-4
    • (1999) Exp Hematol , vol.27 , Issue.10 , pp. 1487-1493
    • Kanda, N.1    Tamaki, K.2
  • 68
    • 0032961008 scopus 로고    scopus 로고
    • Ganglioside GT1b suppresses immunoglobulin production by human peripheral blood mononuclear cells
    • Kanda N, Tamaki K. Ganglioside GT1b suppresses immunoglobulin production by human peripheral blood mononuclear cells. Immunology (1999) 96(4):628-33. doi:10.1046/j.1365-2567.1999.00734.x
    • (1999) Immunology , vol.96 , Issue.4 , pp. 628-633
    • Kanda, N.1    Tamaki, K.2
  • 69
    • 0031725004 scopus 로고    scopus 로고
    • Ganglioside GQ1b enhances Ig production by human PBMCs
    • Kanda N, Tamaki K. Ganglioside GQ1b enhances Ig production by human PBMCs. J Allergy Clin Immunol (1998) 102(5):813-20. doi:10.1016/S0091-6749(98)70022-3
    • (1998) J Allergy Clin Immunol , vol.102 , Issue.5 , pp. 813-820
    • Kanda, N.1    Tamaki, K.2
  • 70
    • 0034125276 scopus 로고    scopus 로고
    • Ganglioside GD1a enhances immunoglobulin production by human peripheral blood mononuclear cells
    • Kanda N, Watanabe S. Ganglioside GD1a enhances immunoglobulin production by human peripheral blood mononuclear cells. Exp Hematol (2000) 28(6):672-9. doi:10.1016/S0301-472X(00)00167-3
    • (2000) Exp Hematol , vol.28 , Issue.6 , pp. 672-679
    • Kanda, N.1    Watanabe, S.2
  • 71
    • 0032006447 scopus 로고    scopus 로고
    • Gangliosides enhance apoptosis of thymocytes
    • Zhou J, Shao H, Cox NR, Baker HJ, Ewald SJ. Gangliosides enhance apoptosis of thymocytes. Cell Immunol (1998) 183(2):90-8. doi:10.1006/cimm.1998.1247
    • (1998) Cell Immunol , vol.183 , Issue.2 , pp. 90-98
    • Zhou, J.1    Shao, H.2    Cox, N.R.3    Baker, H.J.4    Ewald, S.J.5
  • 72
    • 84911483562 scopus 로고    scopus 로고
    • Distinct selectivity of gangliosides required for CD4(+) T and CD8(+) T cell activation
    • Inokuchi J, Nagafuku M, Ohno I, Suzuki A. Distinct selectivity of gangliosides required for CD4(+) T and CD8(+) T cell activation. Biochim Biophys Acta (2015) 1851(1):98-106. doi:10.1016/j.bbalip.2014.07.013
    • (2015) Biochim Biophys Acta , vol.1851 , Issue.1 , pp. 98-106
    • Inokuchi, J.1    Nagafuku, M.2    Ohno, I.3    Suzuki, A.4
  • 73
    • 0038513852 scopus 로고    scopus 로고
    • Intensification of antitumor effect by T helper 1-dominant adoptive immunogene therapy for advanced orthotopic colon cancer
    • Nakamori M, Iwahashi M, Nakamura M, Ueda K, Zhang X, Yamaue H. Intensification of antitumor effect by T helper 1-dominant adoptive immunogene therapy for advanced orthotopic colon cancer. Clin Cancer Res (2003) 9(6):2357-65.
    • (2003) Clin Cancer Res , vol.9 , Issue.6 , pp. 2357-2365
    • Nakamori, M.1    Iwahashi, M.2    Nakamura, M.3    Ueda, K.4    Zhang, X.5    Yamaue, H.6
  • 74
    • 0032709778 scopus 로고    scopus 로고
    • T cell-derived IL-10 promotes lung cancer growth by suppressing both T cell and APC function
    • Sharma S, Stolina M, Lin Y, Gardner B, Miller PW, Kronenberg M, et al. T cell-derived IL-10 promotes lung cancer growth by suppressing both T cell and APC function. J Immunol (1999) 163(9):5020-8.
    • (1999) J Immunol , vol.163 , Issue.9 , pp. 5020-5028
    • Sharma, S.1    Stolina, M.2    Lin, Y.3    Gardner, B.4    Miller, P.W.5    Kronenberg, M.6
  • 75
    • 0030024140 scopus 로고    scopus 로고
    • Disregulation in TH1 and TH2 subsets of CD4+ T cells in peripheral blood of colorectal cancer patients and involvement in cancer establishment and progression
    • Pellegrini P, Berghella AM, Del Beato T, Cicia S, Adorno D, Casciani CU. Disregulation in TH1 and TH2 subsets of CD4+ T cells in peripheral blood of colorectal cancer patients and involvement in cancer establishment and progression. Cancer Immunol Immunother (1996) 42(1):1-8. doi:10.1007/s002620050244
    • (1996) Cancer Immunol Immunother , vol.42 , Issue.1 , pp. 1-8
    • Pellegrini, P.1    Berghella, A.M.2    Del Beato, T.3    Cicia, S.4    Adorno, D.5    Casciani, C.U.6
  • 76
    • 0028174061 scopus 로고
    • Function and activation of NF-kappa B in the immune system
    • Baeuerle PA, Henkel T. Function and activation of NF-kappa B in the immune system. Annu Rev Immunol (1994) 12(1):141-79. doi:10.1146/annurev.iy.12.040194.001041
    • (1994) Annu Rev Immunol , vol.12 , Issue.1 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 77
    • 0032696676 scopus 로고    scopus 로고
    • Renal cell carcinoma-derived gangliosides suppress nuclear factor-kappaB activation in T cells
    • Uzzo RG, Rayman P, Kolenko V, Clark PE, Cathcart MK, Bloom T, et al. Renal cell carcinoma-derived gangliosides suppress nuclear factor-kappaB activation in T cells. J Clin Invest (1999) 104(6):769-76. doi:10.1172/JCI6775
    • (1999) J Clin Invest , vol.104 , Issue.6 , pp. 769-776
    • Uzzo, R.G.1    Rayman, P.2    Kolenko, V.3    Clark, P.E.4    Cathcart, M.K.5    Bloom, T.6
  • 78
    • 12144290522 scopus 로고    scopus 로고
    • Degradation of NF-κB in T cells by gangliosides expressed on renal cell carcinomas
    • Thornton MV, Kudo D, Rayman P, Horton C, Molto L, Cathcart MK, et al. Degradation of NF-κB in T cells by gangliosides expressed on renal cell carcinomas. J Immunol (2004) 172(6):3480-90. doi:10.4049/jimmunol.172.6.3480
    • (2004) J Immunol , vol.172 , Issue.6 , pp. 3480-3490
    • Thornton, M.V.1    Kudo, D.2    Rayman, P.3    Horton, C.4    Molto, L.5    Cathcart, M.K.6
  • 79
    • 33646118015 scopus 로고    scopus 로고
    • The immunoregulatory effects of gangliosides involve immune deviation favoring type-2 T cell responses
    • Crespo FA, Sun X, Cripps JG, Fernandez-Botran R. The immunoregulatory effects of gangliosides involve immune deviation favoring type-2 T cell responses. J Leukoc Biol (2006) 79(3):586-95. doi:10.1189/jlb.0705395
    • (2006) J Leukoc Biol , vol.79 , Issue.3 , pp. 586-595
    • Crespo, F.A.1    Sun, X.2    Cripps, J.G.3    Fernandez-Botran, R.4
  • 80
    • 4644224963 scopus 로고    scopus 로고
    • Effect of renal cell carcinomas on the development of type 1 T-cell responses
    • Rayman P, Wesa AK, Richmond AL, Das T, Biswas K, Raval G, et al. Effect of renal cell carcinomas on the development of type 1 T-cell responses. Clin Cancer Res (2004) 10(18 Pt 2):6360S-6S. doi:10.1158/1078-0432.CCR-050011
    • (2004) Clin Cancer Res , vol.10 , Issue.18 , pp. 6360S-6366S
    • Rayman, P.1    Wesa, A.K.2    Richmond, A.L.3    Das, T.4    Biswas, K.5    Raval, G.6
  • 81
    • 0030588610 scopus 로고    scopus 로고
    • Brain-derived gangliosides regulate the cytokine production and proliferation of activated T cells
    • Irani DN, Lin KI, Griffin DE. Brain-derived gangliosides regulate the cytokine production and proliferation of activated T cells. J Immunol (1996) 157(10):4333-40.
    • (1996) J Immunol , vol.157 , Issue.10 , pp. 4333-4340
    • Irani, D.N.1    Lin, K.I.2    Griffin, D.E.3
  • 82
    • 77954134113 scopus 로고    scopus 로고
    • Elevated levels of select gangliosides in T cells from renal cell carcinoma patients is associated with T cell dysfunction
    • Biswas S, Biswas K, Richmond A, Ko J, Ghosh S, Simmons M, et al. Elevated levels of select gangliosides in T cells from renal cell carcinoma patients is associated with T cell dysfunction. J Immunol (2009) 183(8):5050-8. doi:10.4049/jimmunol.0900259
    • (2009) J Immunol , vol.183 , Issue.8 , pp. 5050-5058
    • Biswas, S.1    Biswas, K.2    Richmond, A.3    Ko, J.4    Ghosh, S.5    Simmons, M.6
  • 83
    • 0037379733 scopus 로고    scopus 로고
    • Gangliosides expressed by the renal cell carcinoma cell line SK-RC-45 are involved in tumor-induced apoptosis of T cells
    • Kudo D, Rayman P, Horton C, Cathcart MK, Bukowski RM, Thornton M, et al. Gangliosides expressed by the renal cell carcinoma cell line SK-RC-45 are involved in tumor-induced apoptosis of T cells. Cancer Res (2003) 63(7):1676-83.
    • (2003) Cancer Res , vol.63 , Issue.7 , pp. 1676-1683
    • Kudo, D.1    Rayman, P.2    Horton, C.3    Cathcart, M.K.4    Bukowski, R.M.5    Thornton, M.6
  • 84
    • 66149137283 scopus 로고    scopus 로고
    • GD3, an overexpressed tumor-derived ganglioside, mediates the apoptosis of activated but not resting T cells
    • Sa G, Das T, Moon C, Hilston CM, Rayman PA, Rini BI, et al. GD3, an overexpressed tumor-derived ganglioside, mediates the apoptosis of activated but not resting T cells. Cancer Res (2009) 69(7):3095-104. doi:10.1158/0008-5472.CAN-08-3776
    • (2009) Cancer Res , vol.69 , Issue.7 , pp. 3095-3104
    • Sa, G.1    Das, T.2    Moon, C.3    Hilston, C.M.4    Rayman, P.A.5    Rini, B.I.6
  • 85
    • 84941992020 scopus 로고    scopus 로고
    • GBM derived gangliosides induce T cell apoptosis through activation of the caspase cascade involving both the extrinsic and the intrinsic pathway
    • Mahata B, Biswas S, Rayman P, Chahlavi A, Ko J, Bhattacharjee A, et al. GBM derived gangliosides induce T cell apoptosis through activation of the caspase cascade involving both the extrinsic and the intrinsic pathway. PLoS One (2015) 10(7):e0134425. doi:10.1371/journal.pone.0134425
    • (2015) PLoS One , vol.10 , Issue.7
    • Mahata, B.1    Biswas, S.2    Rayman, P.3    Chahlavi, A.4    Ko, J.5    Bhattacharjee, A.6
  • 86
    • 34248165998 scopus 로고    scopus 로고
    • TNF-alpha induction of GM2 expression on renal cell carcinomas promotes T cell dysfunction
    • Raval G, Biswas S, Rayman P, Biswas K, Sa G, Ghosh S, et al. TNF-alpha induction of GM2 expression on renal cell carcinomas promotes T cell dysfunction. J Immunol (2007) 178(10):6642-52. doi:10.4049/jimmunol.178.10.6642
    • (2007) J Immunol , vol.178 , Issue.10 , pp. 6642-6652
    • Raval, G.1    Biswas, S.2    Rayman, P.3    Biswas, K.4    Sa, G.5    Ghosh, S.6
  • 87
    • 0027163870 scopus 로고
    • Gangliosides inhibit T-lymphocyte proliferation by preventing the interaction of interleukin-2 with its cell surface receptors
    • Chu JW, Sharom FJ. Gangliosides inhibit T-lymphocyte proliferation by preventing the interaction of interleukin-2 with its cell surface receptors. Immunology (1993) 79(1):10-7.
    • (1993) Immunology , vol.79 , Issue.1 , pp. 10-17
    • Chu, J.W.1    Sharom, F.J.2
  • 88
    • 0033213878 scopus 로고    scopus 로고
    • Tumor gangliosides inhibit the tumor-specific immune response
    • McKallip R, Li R, Ladisch S. Tumor gangliosides inhibit the tumor-specific immune response. J Immunol (1999) 163(7):3718-26.
    • (1999) J Immunol , vol.163 , Issue.7 , pp. 3718-3726
    • McKallip, R.1    Li, R.2    Ladisch, S.3
  • 89
    • 84866536027 scopus 로고    scopus 로고
    • Ganglioside inhibition of CD8+ T cell cytotoxicity: interference with lytic granule trafficking and exocytosis
    • Lee HC, Wondimu A, Liu Y, Ma JS, Radoja S, Ladisch S. Ganglioside inhibition of CD8+ T cell cytotoxicity: interference with lytic granule trafficking and exocytosis. J Immunol (2012) 189(7):3521-7. doi:10.4049/jimmunol.1201256
    • (2012) J Immunol , vol.189 , Issue.7 , pp. 3521-3527
    • Lee, H.C.1    Wondimu, A.2    Liu, Y.3    Ma, J.S.4    Radoja, S.5    Ladisch, S.6
  • 90
    • 77952361779 scopus 로고    scopus 로고
    • Anti-GD3 chimeric sFv-CD28/T-cell receptor zeta designer T cells for treatment of metastatic melanoma and other neuroectodermal tumors
    • Lo AS, Ma Q, Liu DL, Junghans RP. Anti-GD3 chimeric sFv-CD28/T-cell receptor zeta designer T cells for treatment of metastatic melanoma and other neuroectodermal tumors. Clin Cancer Res (2010) 16(10):2769-80. doi:10.1158/1078-0432.CCR-10-0043
    • (2010) Clin Cancer Res , vol.16 , Issue.10 , pp. 2769-2780
    • Lo, A.S.1    Ma, Q.2    Liu, D.L.3    Junghans, R.P.4
  • 91
    • 0030057341 scopus 로고    scopus 로고
    • Vaccine therapy for malignant melanoma
    • Morton DL, Barth A. Vaccine therapy for malignant melanoma. CA Cancer J Clin (1996) 46(4):225-44. doi:10.3322/canjclin.46.4.225
    • (1996) CA Cancer J Clin , vol.46 , Issue.4 , pp. 225-244
    • Morton, D.L.1    Barth, A.2
  • 92
    • 0023618696 scopus 로고
    • Density-dependent recognition of cell surface GM3 by a certain anti-melanoma antibody, and GM3 lactone as a possible immunogen: requirements for tumor-associated antigen and immunogen
    • Nores GA, Dohi T, Taniguchi M, Hakomori S. Density-dependent recognition of cell surface GM3 by a certain anti-melanoma antibody, and GM3 lactone as a possible immunogen: requirements for tumor-associated antigen and immunogen. J Immunol (1987) 139(9):3171-6.
    • (1987) J Immunol , vol.139 , Issue.9 , pp. 3171-3176
    • Nores, G.A.1    Dohi, T.2    Taniguchi, M.3    Hakomori, S.4
  • 93
    • 0022445270 scopus 로고
    • Biosynthesis and expression of the disialoganglioside GD2, a relevant target antigen on small cell lung carcinoma for monoclonal antibody-mediated cytolysis
    • Cheresh DA, Rosenberg J, Mujoo K, Hirschowitz L, Reisfeld RA. Biosynthesis and expression of the disialoganglioside GD2, a relevant target antigen on small cell lung carcinoma for monoclonal antibody-mediated cytolysis. Cancer Res (1986) 46(10):5112-8.
    • (1986) Cancer Res , vol.46 , Issue.10 , pp. 5112-5118
    • Cheresh, D.A.1    Rosenberg, J.2    Mujoo, K.3    Hirschowitz, L.4    Reisfeld, R.A.5
  • 94
    • 0030863078 scopus 로고    scopus 로고
    • Selection of tumor antigens as targets for immune attack using immunohistochemistry: I. Focus on gangliosides
    • Zhang S, Cordon-Cardo C, Zhang HS, Reuter VE, Adluri S, Hamilton WB, et al. Selection of tumor antigens as targets for immune attack using immunohistochemistry: I. Focus on gangliosides. Int J Cancer (1997) 73(1):42-9. doi:10.1002/(SICI)1097-0215(19970926)73:1<42::AID-IJC8>3.0.CO;2-1
    • (1997) Int J Cancer , vol.73 , Issue.1 , pp. 42-49
    • Zhang, S.1    Cordon-Cardo, C.2    Zhang, H.S.3    Reuter, V.E.4    Adluri, S.5    Hamilton, W.B.6
  • 95
    • 0142059844 scopus 로고    scopus 로고
    • Human uptake and incorporation of an immunogenic nonhuman dietary sialic acid
    • Tangvoranuntakul P, Gagneux P, Diaz S, Bardor M, Varki N, Varki A, et al. Human uptake and incorporation of an immunogenic nonhuman dietary sialic acid. Proc Natl Acad Sci U S A (2003) 100(21):12045-50. doi:10.1073/pnas.2131556100
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.21 , pp. 12045-12050
    • Tangvoranuntakul, P.1    Gagneux, P.2    Diaz, S.3    Bardor, M.4    Varki, N.5    Varki, A.6
  • 96
    • 21244478903 scopus 로고    scopus 로고
    • Effects of natural human antibodies against a nonhuman sialic acid that metabolically incorporates into activated and malignant immune cells
    • Nguyen DH, Tangvoranuntakul P, Varki A. Effects of natural human antibodies against a nonhuman sialic acid that metabolically incorporates into activated and malignant immune cells. J Immunol (2005) 175(1):228-36. doi:10.4049/jimmunol.175.1.228
    • (2005) J Immunol , vol.175 , Issue.1 , pp. 228-236
    • Nguyen, D.H.1    Tangvoranuntakul, P.2    Varki, A.3
  • 97
    • 33748691364 scopus 로고    scopus 로고
    • Genetic mechanisms for the synthesis of fucosyl GM1 in small cell lung cancer cell lines
    • Tokuda N, Zhang Q, Yoshida S, Kusunoki S, Urano T, Furukawa K, et al. Genetic mechanisms for the synthesis of fucosyl GM1 in small cell lung cancer cell lines. Glycobiology (2006) 16(10):916-25. doi:10.1093/glycob/cwl022
    • (2006) Glycobiology , vol.16 , Issue.10 , pp. 916-925
    • Tokuda, N.1    Zhang, Q.2    Yoshida, S.3    Kusunoki, S.4    Urano, T.5    Furukawa, K.6
  • 98
    • 84939962940 scopus 로고    scopus 로고
    • Targeting of tumor-associated gangliosides with antibodies affects signaling pathways and leads to cell death including apoptosis
    • Horwacik I, Rokita H. Targeting of tumor-associated gangliosides with antibodies affects signaling pathways and leads to cell death including apoptosis. Apoptosis (2015) 20(5):679-88. doi:10.1007/s10495-015-1103-7
    • (2015) Apoptosis , vol.20 , Issue.5 , pp. 679-688
    • Horwacik, I.1    Rokita, H.2
  • 99
    • 84925463158 scopus 로고    scopus 로고
    • GM3 and cancer
    • Hakomori SI, Handa K. GM3 and cancer. Glycoconj J (2015) 32(1-2):1-8. doi:10.1007/s10719-014-9572-4
    • (2015) Glycoconj J , vol.32 , Issue.1-2 , pp. 1-8
    • Hakomori, S.I.1    Handa, K.2
  • 101
    • 84892369775 scopus 로고    scopus 로고
    • Engineering anti-GD2 monoclonal antibodies for cancer immunotherapy
    • Ahmed M, Cheung NK. Engineering anti-GD2 monoclonal antibodies for cancer immunotherapy. FEBS Lett (2014) 588(2):288-97. doi:10.1016/j.febslet.2013.11.030
    • (2014) FEBS Lett , vol.588 , Issue.2 , pp. 288-297
    • Ahmed, M.1    Cheung, N.K.2
  • 102
    • 84890636648 scopus 로고    scopus 로고
    • Anti-idiotype antibodies in cancer treatment: the pharmaceutical industry perspective
    • Gómez RE, Ardigo ML. Anti-idiotype antibodies in cancer treatment: the pharmaceutical industry perspective. Front Oncol (2012) 2:147. doi:10.3389/fonc.2012.00147
    • (2012) Front Oncol , vol.2 , pp. 147
    • Gómez, R.E.1    Ardigo, M.L.2
  • 103
    • 9844267313 scopus 로고    scopus 로고
    • Anti-melanoma effects of R24, a monoclonal antibody against GD3 ganglioside
    • Nasi ML, Meyers M, Livingston PO, Houghton AN, Chapman PB. Anti-melanoma effects of R24, a monoclonal antibody against GD3 ganglioside. Melanoma Res (1997) 7:S155-62. doi:10.1097/00008390-199708001-00024
    • (1997) Melanoma Res , vol.7 , pp. S155-S162
    • Nasi, M.L.1    Meyers, M.2    Livingston, P.O.3    Houghton, A.N.4    Chapman, P.B.5
  • 104
    • 0026263939 scopus 로고
    • Role of gangliosides in active immunotherapy with melanoma vaccine
    • Ravindranath MH, Morton DL. Role of gangliosides in active immunotherapy with melanoma vaccine. Int Rev Immunol (1991) 7(4):303-29. doi:10.3109/08830189109114877
    • (1991) Int Rev Immunol , vol.7 , Issue.4 , pp. 303-329
    • Ravindranath, M.H.1    Morton, D.L.2
  • 105
    • 22944474953 scopus 로고    scopus 로고
    • Carbohydrate vaccines as immunotherapy for cancer
    • Slovin SF, Keding SJ, Ragupathi G. Carbohydrate vaccines as immunotherapy for cancer. Immunol Cell Biol (2005) 83(4):418-28. doi:10.1111/j.1440-1711.2005.01350.x
    • (2005) Immunol Cell Biol , vol.83 , Issue.4 , pp. 418-428
    • Slovin, S.F.1    Keding, S.J.2    Ragupathi, G.3
  • 106
    • 84879360237 scopus 로고    scopus 로고
    • Positioning ganglioside D3 as an immunotherapeutic target in lymphangioleiomyomatosis
    • Gilbert ER, Eby JM, Hammer AM, Klarquist J, Christensen DG, Barfuss AJ, et al. Positioning ganglioside D3 as an immunotherapeutic target in lymphangioleiomyomatosis. Am J Pathol (2013) 183(1):226-34. doi:10.1016/j.ajpath.2013.04.002
    • (2013) Am J Pathol , vol.183 , Issue.1 , pp. 226-234
    • Gilbert, E.R.1    Eby, J.M.2    Hammer, A.M.3    Klarquist, J.4    Christensen, D.G.5    Barfuss, A.J.6
  • 107
    • 0020003718 scopus 로고
    • GD3, a prominent ganglioside of human melanoma. Detection and characterisation by mouse monoclonal antibody
    • Pukel CS, Lloyd KO, Travassos LR, Dippold WG, Oettgen HF, Old LJ. GD3, a prominent ganglioside of human melanoma. Detection and characterisation by mouse monoclonal antibody. J Exp Med (1982) 155(4):1133-47. doi:10.1084/jem.155.4.1133
    • (1982) J Exp Med , vol.155 , Issue.4 , pp. 1133-1147
    • Pukel, C.S.1    Lloyd, K.O.2    Travassos, L.R.3    Dippold, W.G.4    Oettgen, H.F.5    Old, L.J.6
  • 108
    • 33646861813 scopus 로고    scopus 로고
    • The antibody to GD3 ganglioside, R24, is rapidly endocytosed and recycled to the plasma membrane via the endocytic recycling compartment. Inhibitory effect of brefeldin A and monensin
    • Iglesias-Bartolomé R, Crespo PM, Gomez GA, Daniotti JL. The antibody to GD3 ganglioside, R24, is rapidly endocytosed and recycled to the plasma membrane via the endocytic recycling compartment. Inhibitory effect of brefeldin A and monensin. FEBS J (2006) 273(8):1744-58. doi:10.1111/j.1742-4658.2006.05194.x
    • (2006) FEBS J , vol.273 , Issue.8 , pp. 1744-1758
    • Iglesias-Bartolomé, R.1    Crespo, P.M.2    Gomez, G.A.3    Daniotti, J.L.4
  • 109
    • 84873179422 scopus 로고    scopus 로고
    • Targeted delivery of immunotoxin by antibody to ganglioside GD3: a novel drug delivery route for tumor cells
    • Torres Demichelis V, Vilcaes AA, Iglesias-Bartolomé R, Ruggiero FM, Daniotti JL. Targeted delivery of immunotoxin by antibody to ganglioside GD3: a novel drug delivery route for tumor cells. PLoS One (2013) 8(1):e55304. doi:10.1371/journal.pone.0055304
    • (2013) PLoS One , vol.8 , Issue.1
    • Torres Demichelis, V.1    Vilcaes, A.A.2    Iglesias-Bartolomé, R.3    Ruggiero, F.M.4    Daniotti, J.L.5
  • 110
    • 84920397906 scopus 로고    scopus 로고
    • Dual targeting NG2 and GD3A using Mab-Zap immunotoxin results in reduced glioma cell viability in vitro
    • Higgins SC, Fillmore HL, Ashkan K, Butt AM, Pilkington GJ. Dual targeting NG2 and GD3A using Mab-Zap immunotoxin results in reduced glioma cell viability in vitro. Anticancer Res (2015) 35(1):77-84.
    • (2015) Anticancer Res , vol.35 , Issue.1 , pp. 77-84
    • Higgins, S.C.1    Fillmore, H.L.2    Ashkan, K.3    Butt, A.M.4    Pilkington, G.J.5
  • 111
    • 0035862692 scopus 로고    scopus 로고
    • Taxane-antibody conjugates afford potent cytotoxicity, enhanced solubility, and tumor target selectivity
    • Guillemard V, Saragovi HU. Taxane-antibody conjugates afford potent cytotoxicity, enhanced solubility, and tumor target selectivity. Cancer Res (2001) 61(2):694-9.
    • (2001) Cancer Res , vol.61 , Issue.2 , pp. 694-699
    • Guillemard, V.1    Saragovi, H.U.2
  • 112
    • 2442666714 scopus 로고    scopus 로고
    • Prodrug chemotherapeutics bypass p-glycoprotein resistance and kill tumors in vivo with high efficacy and target-dependent selectivity
    • Guillemard V, Uri Saragovi H. Prodrug chemotherapeutics bypass p-glycoprotein resistance and kill tumors in vivo with high efficacy and target-dependent selectivity. Oncogene (2004) 23(20):3613-21. doi:10.1038/sj.onc.1207463
    • (2004) Oncogene , vol.23 , Issue.20 , pp. 3613-3621
    • Guillemard, V.1    Uri Saragovi, H.2
  • 113
    • 84899719886 scopus 로고    scopus 로고
    • Racotumomab-a novel anti-idiotype monoclonal antibody vaccine for the treatment of cancer
    • Gajdosik Z. Racotumomab-a novel anti-idiotype monoclonal antibody vaccine for the treatment of cancer. Drugs Today (Barc) (2014) 50(4):301-7. doi:10.1358/dot.2014.50.4.2116670
    • (2014) Drugs Today (Barc) , vol.50 , Issue.4 , pp. 301-307
    • Gajdosik, Z.1
  • 114
    • 84904386095 scopus 로고    scopus 로고
    • A randomized, multicenter, placebo-controlled clinical trial of racotumomab-alum vaccine as switch maintenance therapy in advanced non-small cell lung cancer patients
    • Alfonso S, Valdés-Zayas A, Santiesteban ER, Flores YI, Areces F, Hernández M, et al. A randomized, multicenter, placebo-controlled clinical trial of racotumomab-alum vaccine as switch maintenance therapy in advanced non-small cell lung cancer patients. Clin Cancer Res (2014) 20(14):3660-71. doi:10.1158/1078-0432.CCR-13-1674
    • (2014) Clin Cancer Res , vol.20 , Issue.14 , pp. 3660-3671
    • Alfonso, S.1    Valdés-Zayas, A.2    Santiesteban, E.R.3    Flores, Y.I.4    Areces, F.5    Hernández, M.6
  • 115
    • 77957341503 scopus 로고    scopus 로고
    • Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma
    • Yu AL, Gilman AL, Ozkaynak MF, London WB, Kreissman SG, Chen HX, et al. Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma. N Engl J Med (2010) 363(14):1324-34. doi:10.1056/NEJMoa0911123
    • (2010) N Engl J Med , vol.363 , Issue.14 , pp. 1324-1334
    • Yu, A.L.1    Gilman, A.L.2    Ozkaynak, M.F.3    London, W.B.4    Kreissman, S.G.5    Chen, H.X.6
  • 116
    • 84902962349 scopus 로고    scopus 로고
    • Phase I trial of a novel anti-GD2 monoclonal antibody, Hu14.18K322A, designed to decrease toxicity in children with refractory or recurrent neuroblastoma
    • Navid F, Sondel PM, Barfield R, Shulkin BL, Kaufman RA, Allay JA, et al. Phase I trial of a novel anti-GD2 monoclonal antibody, Hu14.18K322A, designed to decrease toxicity in children with refractory or recurrent neuroblastoma. J Clin Oncol (2014) 32(14):1445-52. doi:10.1200/JCO.2013.50.4423
    • (2014) J Clin Oncol , vol.32 , Issue.14 , pp. 1445-1452
    • Navid, F.1    Sondel, P.M.2    Barfield, R.3    Shulkin, B.L.4    Kaufman, R.A.5    Allay, J.A.6
  • 117
    • 79951886003 scopus 로고    scopus 로고
    • Antitumor activity of hu14.18-IL2 in patients with relapsed/refractory neuroblastoma: a Children's Oncology Group (COG) phase II study
    • Shusterman S, London WB, Gillies SD, Hank JA, Voss SD, Seeger RC, et al. Antitumor activity of hu14.18-IL2 in patients with relapsed/refractory neuroblastoma: a Children's Oncology Group (COG) phase II study. J Clin Oncol (2010) 28(33):4969-75. doi:10.1200/JCO.2009.27.8861
    • (2010) J Clin Oncol , vol.28 , Issue.33 , pp. 4969-4975
    • Shusterman, S.1    London, W.B.2    Gillies, S.D.3    Hank, J.A.4    Voss, S.D.5    Seeger, R.C.6
  • 119
    • 84909581250 scopus 로고    scopus 로고
    • Antibody-cytokine fusion proteins for treatment of cancer: engineering cytokines for improved efficacy and safety
    • Young PA, Morrison SL, Timmerman JM. Antibody-cytokine fusion proteins for treatment of cancer: engineering cytokines for improved efficacy and safety. Semin Oncol (2014) 41(5):623-36. doi:10.1053/j.seminoncol.2014.08.002
    • (2014) Semin Oncol , vol.41 , Issue.5 , pp. 623-636
    • Young, P.A.1    Morrison, S.L.2    Timmerman, J.M.3
  • 120
    • 84856267795 scopus 로고    scopus 로고
    • NK cells engineered to express a GD2-specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin
    • Esser R, Müller T, Stefes D, Kloess S, Seidel D, Gillies SD, et al. NK cells engineered to express a GD2-specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin. J Cell Mol Med (2012) 16(3):569-81. doi:10.1111/j.1582-4934.2011.01343.x
    • (2012) J Cell Mol Med , vol.16 , Issue.3 , pp. 569-581
    • Esser, R.1    Müller, T.2    Stefes, D.3    Kloess, S.4    Seidel, D.5    Gillies, S.D.6
  • 121
    • 84878849601 scopus 로고    scopus 로고
    • Vaccination with anti-idiotype antibody ganglidiomab mediates a GD(2)-specific anti-neuroblastoma immune response
    • Lode HN, Schmidt M, Seidel D, Huebener N, Brackrock D, Bleeke M, et al. Vaccination with anti-idiotype antibody ganglidiomab mediates a GD(2)-specific anti-neuroblastoma immune response. Cancer Immunol Immunother (2013) 62(6):999-1010. doi:10.1007/s00262-013-1413-y
    • (2013) Cancer Immunol Immunother , vol.62 , Issue.6 , pp. 999-1010
    • Lode, H.N.1    Schmidt, M.2    Seidel, D.3    Huebener, N.4    Brackrock, D.5    Bleeke, M.6
  • 122
    • 78650837399 scopus 로고    scopus 로고
    • Triptolide downregulates human GD3 synthase (hST8Sia I) gene expression in SK-MEL-2 human melanoma cells
    • Kwon HY, Kim SJ, Kim CH, Son SW, Kim KS, Lee JH, et al. Triptolide downregulates human GD3 synthase (hST8Sia I) gene expression in SK-MEL-2 human melanoma cells. Exp Mol Med (2010) 42(12):849-55. doi:10.3858/emm.2010.42.12.088
    • (2010) Exp Mol Med , vol.42 , Issue.12 , pp. 849-855
    • Kwon, H.Y.1    Kim, S.J.2    Kim, C.H.3    Son, S.W.4    Kim, K.S.5    Lee, J.H.6
  • 123
    • 84861801520 scopus 로고    scopus 로고
    • Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis
    • Battula VL, Shi Y, Evans KW, Wang RY, Spaeth EL, Jacamo RO, et al. Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis. J Clin Invest (2012) 122(6):2066-78. doi:10.1172/JCI59735
    • (2012) J Clin Invest , vol.122 , Issue.6 , pp. 2066-2078
    • Battula, V.L.1    Shi, Y.2    Evans, K.W.3    Wang, R.Y.4    Spaeth, E.L.5    Jacamo, R.O.6
  • 124
    • 84930542981 scopus 로고    scopus 로고
    • GD3 synthase regulates epithelial-mesenchymal transition and metastasis in breast cancer
    • Sarkar TR, Battula VL, Werden SJ, Vijay GV, Ramirez-Peña EQ, Taube JH, et al. GD3 synthase regulates epithelial-mesenchymal transition and metastasis in breast cancer. Oncogene (2015) 34(23):2958-67. doi:10.1038/onc.2014.245
    • (2015) Oncogene , vol.34 , Issue.23 , pp. 2958-2967
    • Sarkar, T.R.1    Battula, V.L.2    Werden, S.J.3    Vijay, G.V.4    Ramirez-Peña, E.Q.5    Taube, J.H.6
  • 125
    • 67649980009 scopus 로고    scopus 로고
    • From synthesis to biologics: preclinical data on a chemistry derived anticancer vaccine
    • Zhu J, Wan Q, Lee D, Yang G, Spassova MK, Ouerfelli O, et al. From synthesis to biologics: preclinical data on a chemistry derived anticancer vaccine. J Am Chem Soc (2009) 131(26):9298-303. doi:10.1021/ja901415s
    • (2009) J Am Chem Soc , vol.131 , Issue.26 , pp. 9298-9303
    • Zhu, J.1    Wan, Q.2    Lee, D.3    Yang, G.4    Spassova, M.K.5    Ouerfelli, O.6
  • 126
    • 0034219460 scopus 로고    scopus 로고
    • Antitumor properties of an anti-idiotypic monoclonal antibody in relation to N-glycolyl-containing gangliosides
    • Vázquez AM, Gabri MR, Hernández AM, Alonso DF, Beausoleil I, Gomez DE, et al. Antitumor properties of an anti-idiotypic monoclonal antibody in relation to N-glycolyl-containing gangliosides. Oncol Rep (2000) 7(4):751-6. doi:10.3892/or.7.4.751
    • (2000) Oncol Rep , vol.7 , Issue.4 , pp. 751-756
    • Vázquez, A.M.1    Gabri, M.R.2    Hernández, A.M.3    Alonso, D.F.4    Beausoleil, I.5    Gomez, D.E.6
  • 127
    • 0036498936 scopus 로고    scopus 로고
    • An anti-idiotype vaccine elicits a specific response to N-glycolyl sialic acid residues of glycoconjugates in melanoma patients
    • Alfonso M, Díaz A, Hernández AM, Pérez A, Rodríguez E, Bitton R, et al. An anti-idiotype vaccine elicits a specific response to N-glycolyl sialic acid residues of glycoconjugates in melanoma patients. J Immunol (2002) 168(5):2523-9. doi:10.4049/jimmunol.168.5.2523
    • (2002) J Immunol , vol.168 , Issue.5 , pp. 2523-2529
    • Alfonso, M.1    Díaz, A.2    Hernández, A.M.3    Pérez, A.4    Rodríguez, E.5    Bitton, R.6
  • 128
    • 0029586061 scopus 로고
    • Generation of a murine monoclonal antibody specific for N-glycolylneuraminic acid-containing gangliosides that also recognizes sulfated glycolipids
    • Vázquez AM, Alfonso M, Lanne B, Karlsson KA, Carr A, Barroso O, et al. Generation of a murine monoclonal antibody specific for N-glycolylneuraminic acid-containing gangliosides that also recognizes sulfated glycolipids. Hybridoma (1995) 14(6):551-6. doi:10.1089/hyb.1995.14.551
    • (1995) Hybridoma , vol.14 , Issue.6 , pp. 551-556
    • Vázquez, A.M.1    Alfonso, M.2    Lanne, B.3    Karlsson, K.A.4    Carr, A.5    Barroso, O.6
  • 129
    • 67650394884 scopus 로고    scopus 로고
    • Tissue micro array analysis of ganglioside N-glycolyl GM3 expression and signal transducer and activator of transcription (STAT)-3 activation in relation to dendritic cell infiltration and microvessel density in non-small cell lung cancer
    • van Cruijsen H, Ruiz MG, van der Valk P, de Gruijl TD, Giaccone G. Tissue micro array analysis of ganglioside N-glycolyl GM3 expression and signal transducer and activator of transcription (STAT)-3 activation in relation to dendritic cell infiltration and microvessel density in non-small cell lung cancer. BMC Cancer (2009) 9:180. doi:10.1186/1471-2407-9-180
    • (2009) BMC Cancer , vol.9 , pp. 180
    • van Cruijsen, H.1    Ruiz, M.G.2    van der Valk, P.3    de Gruijl, T.D.4    Giaccone, G.5
  • 130
    • 84929413003 scopus 로고    scopus 로고
    • Immunoreactivity of the 14F7 Mab raised against N-glycolyl GM3 ganglioside in retinoblastoma tumours
    • Torbidoni AV, Scursoni A, Camarero S, Segatori V, Gabri M, Alonso D, et al. Immunoreactivity of the 14F7 Mab raised against N-glycolyl GM3 ganglioside in retinoblastoma tumours. Acta Ophthalmol (2015) 93(4):e294-300. doi:10.1111/aos.12578
    • (2015) Acta Ophthalmol , vol.93 , Issue.4 , pp. e294-e300
    • Torbidoni, A.V.1    Scursoni, A.2    Camarero, S.3    Segatori, V.4    Gabri, M.5    Alonso, D.6
  • 131
    • 84896874589 scopus 로고    scopus 로고
    • Prognostic role of 14F7 Mab immunoreactivity against N-glycolyl GM3 ganglioside in colon cancer
    • Lahera T, Calvo A, Torres G, Rengifo CE, Quintero S, Arango Mdel C, et al. Prognostic role of 14F7 Mab immunoreactivity against N-glycolyl GM3 ganglioside in colon cancer. J Oncol (2014) 2014:482301. doi:10.1155/2014/482301
    • (2014) J Oncol , vol.2014
    • Lahera, T.1    Calvo, A.2    Torres, G.3    Rengifo, C.E.4    Quintero, S.5    Arango Mdel, C.6
  • 132
    • 84945465953 scopus 로고    scopus 로고
    • A phase I study of the anti-idiotype vaccine racotumomab in neuroblastoma and other pediatric refractory malignancies
    • Cacciavillano W, Sampor C, Venier C, Gabri MR, de Dávila MT, Galluzzo ML, et al. A phase I study of the anti-idiotype vaccine racotumomab in neuroblastoma and other pediatric refractory malignancies. Pediatr Blood Cancer (2015) 62(12):2120-4. doi:10.1002/pbc.25631
    • (2015) Pediatr Blood Cancer , vol.62 , Issue.12 , pp. 2120-2124
    • Cacciavillano, W.1    Sampor, C.2    Venier, C.3    Gabri, M.R.4    de Dávila, M.T.5    Galluzzo, M.L.6
  • 133
    • 58149456558 scopus 로고    scopus 로고
    • Characterization of the antibody response against NeuGcGM3 ganglioside elicited in non-small cell lung cancer patients immunized with an anti-idiotype antibody
    • Hernández AM, Toledo D, Martínez D, Griñán T, Brito V, Macías A, et al. Characterization of the antibody response against NeuGcGM3 ganglioside elicited in non-small cell lung cancer patients immunized with an anti-idiotype antibody. J Immunol (2008) 181(9):6625-34. doi:10.4049/jimmunol.181.9.6625
    • (2008) J Immunol , vol.181 , Issue.9 , pp. 6625-6634
    • Hernández, A.M.1    Toledo, D.2    Martínez, D.3    Griñán, T.4    Brito, V.5    Macías, A.6
  • 134
    • 84884586196 scopus 로고    scopus 로고
    • Racotumomab: an anti-idiotype vaccine related to N-glycolyl-containing gangliosides-preclinical and clinical data
    • Vázquez AM, Hernández AM, Macías A, Montero E, Gómez DE, Alonso DF, et al. Racotumomab: an anti-idiotype vaccine related to N-glycolyl-containing gangliosides-preclinical and clinical data. Front Oncol (2012) 2:150. doi:10.3389/fonc.2012.00150
    • (2012) Front Oncol , vol.2 , pp. 150
    • Vázquez, A.M.1    Hernández, A.M.2    Macías, A.3    Montero, E.4    Gómez, D.E.5    Alonso, D.F.6
  • 135
    • 18544404283 scopus 로고    scopus 로고
    • Natural IgM antibodies and immunosurveillance mechanisms against epithelial cancer cells in humans
    • Brändlein S, Pohle T, RuoffN, Wozniak E, Müller-Hermelink HK, Vollmers HP. Natural IgM antibodies and immunosurveillance mechanisms against epithelial cancer cells in humans. Cancer Res (2003) 63(22):7995-8005.
    • (2003) Cancer Res , vol.63 , Issue.22 , pp. 7995-8005
    • Brändlein, S.1    Pohle, T.2    Ruoff, N.3    Wozniak, E.4    Müller-Hermelink, H.K.5    Vollmers, H.P.6
  • 136
    • 84872842559 scopus 로고    scopus 로고
    • Identification and validation of new autoantibodies for the diagnosis of DCIS and node negative early-stage breast cancers
    • Lacombe J, Mangé A, Jarlier M, Bascoul-Mollevi C, Rouanet P, Lamy PJ, et al. Identification and validation of new autoantibodies for the diagnosis of DCIS and node negative early-stage breast cancers. Int J Cancer (2013) 132(5):1105-13. doi:10.1002/ijc.27766
    • (2013) Int J Cancer , vol.132 , Issue.5 , pp. 1105-1113
    • Lacombe, J.1    Mangé, A.2    Jarlier, M.3    Bascoul-Mollevi, C.4    Rouanet, P.5    Lamy, P.J.6
  • 137
    • 84920719200 scopus 로고    scopus 로고
    • The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites
    • Schneider C, Smith DF, Cummings RD, Boligan KF, Hamilton RG, Bochner BS, et al. The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites. Sci Transl Med (2015) 7(269):269ra1. doi:10.1126/scitranslmed.3010524
    • (2015) Sci Transl Med , vol.7 , Issue.269
    • Schneider, C.1    Smith, D.F.2    Cummings, R.D.3    Boligan, K.F.4    Hamilton, R.G.5    Bochner, B.S.6
  • 138
    • 84959532848 scopus 로고    scopus 로고
    • Anti-NeuGcGM3 reactivity: a possible role of natural antibodies and B-1 cells in tumor immunosurveillance
    • Rodriguez-Zhurbenko N, Rabade-Chediak M, Martinez D, Griñan T, Hernandez AM. Anti-NeuGcGM3 reactivity: a possible role of natural antibodies and B-1 cells in tumor immunosurveillance. Ann N Y Acad Sci (2015) 1362(1):224-38. doi:10.1111/nyas.12827
    • (2015) Ann N Y Acad Sci , vol.1362 , Issue.1 , pp. 224-238
    • Rodriguez-Zhurbenko, N.1    Rabade-Chediak, M.2    Martinez, D.3    Griñan, T.4    Hernandez, A.M.5
  • 140
    • 69049089548 scopus 로고    scopus 로고
    • The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research
    • Cheever MA, Allison JP, Ferris AS, Finn OJ, Hastings BM, Hecht TT, et al. The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research. Clin Cancer Res (2009) 15(17):5323-37. doi:10.1158/1078-0432.CCR-09-0737
    • (2009) Clin Cancer Res , vol.15 , Issue.17 , pp. 5323-5337
    • Cheever, M.A.1    Allison, J.P.2    Ferris, A.S.3    Finn, O.J.4    Hastings, B.M.5    Hecht, T.T.6
  • 141
    • 84861152766 scopus 로고    scopus 로고
    • Promising therapeutic targets in neuroblastoma
    • Matthay KK, George RE, Yu AL. Promising therapeutic targets in neuroblastoma. Clin Cancer Res (2012) 18(10):2740-53. doi:10.1158/1078-0432.CCR-11-1939
    • (2012) Clin Cancer Res , vol.18 , Issue.10 , pp. 2740-2753
    • Matthay, K.K.1    George, R.E.2    Yu, A.L.3
  • 142
    • 84873951706 scopus 로고    scopus 로고
    • Targeted immunotherapy for high-risk neuroblastoma-the role of monoclonal antibodies
    • Parsons K, Bernhardt B, Strickland B. Targeted immunotherapy for high-risk neuroblastoma-the role of monoclonal antibodies. Ann Pharmacother (2013) 47(2):210-8. doi:10.1345/aph.1R353
    • (2013) Ann Pharmacother , vol.47 , Issue.2 , pp. 210-218
    • Parsons, K.1    Bernhardt, B.2    Strickland, B.3
  • 143
    • 55549145071 scopus 로고    scopus 로고
    • Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
    • Pule MA, Savoldo B, Myers GD, Rossig C, Russell HV, Dotti G, et al. Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma. Nat Med (2008) 14(11):1264-70. doi:10.1038/nm.1882
    • (2008) Nat Med , vol.14 , Issue.11 , pp. 1264-1270
    • Pule, M.A.1    Savoldo, B.2    Myers, G.D.3    Rossig, C.4    Russell, H.V.5    Dotti, G.6
  • 144
    • 82955207691 scopus 로고    scopus 로고
    • Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma
    • Louis CU, Savoldo B, Dotti G, Pule M, Yvon E, Myers GD, et al. Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma. Blood (2011) 118(23):6050-6. doi:10.1182/blood-2011-05-354449
    • (2011) Blood , vol.118 , Issue.23 , pp. 6050-6056
    • Louis, C.U.1    Savoldo, B.2    Dotti, G.3    Pule, M.4    Yvon, E.5    Myers, G.D.6
  • 145
    • 84903906267 scopus 로고    scopus 로고
    • Tumor gangliosides accelerate murine tumor angiogenesis
    • Liu Y, Wondimu A, Yan S, Bobb D, Ladisch S. Tumor gangliosides accelerate murine tumor angiogenesis. Angiogenesis (2014) 17(3):563-71. doi:10.1007/s10456-013-9403-4
    • (2014) Angiogenesis , vol.17 , Issue.3 , pp. 563-571
    • Liu, Y.1    Wondimu, A.2    Yan, S.3    Bobb, D.4    Ladisch, S.5
  • 146
    • 0142059048 scopus 로고    scopus 로고
    • N-butyldeoxynojirimycin inhibits murine melanoma cell ganglioside metabolism and delays tumor onset
    • Guerrera M, Ladisch S. N-butyldeoxynojirimycin inhibits murine melanoma cell ganglioside metabolism and delays tumor onset. Cancer Lett (2003) 201(1):31-40. doi:10.1016/S0304-3835(03)00459-2
    • (2003) Cancer Lett , vol.201 , Issue.1 , pp. 31-40
    • Guerrera, M.1    Ladisch, S.2
  • 147
    • 84892660786 scopus 로고    scopus 로고
    • Glycotherapy: new advances inspire a reemergence of glycans in medicine
    • Hudak JE, Bertozzi CR. Glycotherapy: new advances inspire a reemergence of glycans in medicine. Chem Biol (2014) 21(1):16-37. doi:10.1016/j.chembiol.2013.09.010
    • (2014) Chem Biol , vol.21 , Issue.1 , pp. 16-37
    • Hudak, J.E.1    Bertozzi, C.R.2
  • 148
    • 0035853030 scopus 로고    scopus 로고
    • Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial
    • Gilewski T, Ragupathi G, Bhuta S, Williams LJ, Musselli C, Zhang XF, et al. Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial. Proc Natl Acad Sci U S A (2001) 98(6):3270-5. doi:10.1073/pnas.051626298
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.6 , pp. 3270-3275
    • Gilewski, T.1    Ragupathi, G.2    Bhuta, S.3    Williams, L.J.4    Musselli, C.5    Zhang, X.F.6
  • 149
    • 84873714203 scopus 로고    scopus 로고
    • Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer
    • Huang YL, Hung JT, Cheung SK, Lee HY, Chu KC, Li ST, et al. Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer. Proc Natl Acad Sci U S A (2013) 110(7):2517-22. doi:10.1073/pnas.1222649110
    • (2013) Proc Natl Acad Sci U S A , vol.110 , Issue.7 , pp. 2517-2522
    • Huang, Y.L.1    Hung, J.T.2    Cheung, S.K.3    Lee, H.Y.4    Chu, K.C.5    Li, S.T.6
  • 150
    • 84871025107 scopus 로고    scopus 로고
    • Combining synthetic carbohydrate vaccines with cancer cell glycoengineering for effective cancer immunotherapy
    • Qiu L, Gong X, Wang Q, Li J, Hu H, Wu Q, et al. Combining synthetic carbohydrate vaccines with cancer cell glycoengineering for effective cancer immunotherapy. Cancer Immunol Immunother (2012) 61(11):2045-54. doi:10.1007/s00262-012-1224-6
    • (2012) Cancer Immunol Immunother , vol.61 , Issue.11 , pp. 2045-2054
    • Qiu, L.1    Gong, X.2    Wang, Q.3    Li, J.4    Hu, H.5    Wu, Q.6
  • 151
    • 35348869374 scopus 로고    scopus 로고
    • Efficient glycoengineering of GM3 on melanoma cell and monoclonal antibody-mediated selective killing of the glycoengineered cancer cell
    • Wang Q, Zhang J, Guo Z. Efficient glycoengineering of GM3 on melanoma cell and monoclonal antibody-mediated selective killing of the glycoengineered cancer cell. Bioorg Med Chem (2007) 15(24):7561-7. doi:10.1016/j.bmc.2007.09.005
    • (2007) Bioorg Med Chem , vol.15 , Issue.24 , pp. 7561-7567
    • Wang, Q.1    Zhang, J.2    Guo, Z.3
  • 152
    • 84929885314 scopus 로고    scopus 로고
    • Building better monoclonal antibody-based therapeutics
    • Weiner GJ. Building better monoclonal antibody-based therapeutics. Nat Rev Cancer (2015) 15(6):361-70. doi:10.1038/nrc3930
    • (2015) Nat Rev Cancer , vol.15 , Issue.6 , pp. 361-370
    • Weiner, G.J.1
  • 153
    • 84899096210 scopus 로고    scopus 로고
    • Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies
    • Pearce OM, Läubli H, Verhagen A, Secrest P, Zhang J, Varki NM, et al. Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies. Proc Natl Acad Sci U S A (2014) 111(16):5998-6003. doi:10.1073/pnas.1209067111
    • (2014) Proc Natl Acad Sci U S A , vol.111 , Issue.16 , pp. 5998-6003
    • Pearce, O.M.1    Läubli, H.2    Verhagen, A.3    Secrest, P.4    Zhang, J.5    Varki, N.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.