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Volumn 20, Issue 5, 2015, Pages 679-688

Targeting of tumor-associated gangliosides with antibodies affects signaling pathways and leads to cell death including apoptosis

Author keywords

Antibody; Apoptosis; Cancer; Cell death; Ganglioside; Glycosphingolipid

Indexed keywords

ANTINEOPLASTIC AGENT; GANGLIOSIDE; MONOCLONAL ANTIBODY;

EID: 84939962940     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-015-1103-7     Document Type: Article
Times cited : (30)

References (62)
  • 1
    • 80053060999 scopus 로고    scopus 로고
    • Structures, biosynthesis, and functions of gangliosides-an overview
    • 3684167 1:CAS:528:DC%2BC3MXht1Gns7jK 21937853
    • Yu RK, Tsai YT, Ariga T, Yanagisawa M (2011) Structures, biosynthesis, and functions of gangliosides-an overview. J Oleo Sci 60:537-544
    • (2011) J Oleo Sci , vol.60 , pp. 537-544
    • Yu, R.K.1    Tsai, Y.T.2    Ariga, T.3    Yanagisawa, M.4
  • 2
    • 3543085572 scopus 로고    scopus 로고
    • Ganglioside/glycosphingolipid turnover: New concepts
    • 1:CAS:528:DC%2BD2cXlt1OktbY%3D 15229395
    • Tettamanti G (2004) Ganglioside/glycosphingolipid turnover: new concepts. Glycoconj J 20:301-317
    • (2004) Glycoconj J , vol.20 , pp. 301-317
    • Tettamanti, G.1
  • 3
    • 79959960171 scopus 로고    scopus 로고
    • Chip-based nanoelectrospray mass spectrometry of brain gangliosides
    • 10.1016/j.bbalip.2011.06.008 1:CAS:528:DC%2BC3MXptlSrs7s%3D 21704187
    • Flangea C, Serb A, Sisu E, Zamfir AD (2011) Chip-based nanoelectrospray mass spectrometry of brain gangliosides. Biochim Biophys Acta 1811:513-535. doi: 10.1016/j.bbalip.2011.06.008
    • (2011) Biochim Biophys Acta , vol.1811 , pp. 513-535
    • Flangea, C.1    Serb, A.2    Sisu, E.3    Zamfir, A.D.4
  • 4
    • 84897533476 scopus 로고    scopus 로고
    • Early stage fetal neocortex exhibits a complex ganglioside profile as revealed by high resolution tandem mass spectrometry
    • 1:CAS:528:DC%2BC2cXkslWis78%3D 24658680
    • Ghiulai RM, Sarbu M, Vukelić Ž, Ilie C, Zamfir AD (2014) Early stage fetal neocortex exhibits a complex ganglioside profile as revealed by high resolution tandem mass spectrometry. Glycoconj J 31:231-245
    • (2014) Glycoconj J , vol.31 , pp. 231-245
    • Ghiulai, R.M.1    Sarbu, M.2    Vukelić, Ž.3    Ilie, C.4    Zamfir, A.D.5
  • 5
    • 0036895610 scopus 로고    scopus 로고
    • Peripheral neuropathies and anti-glycolipid antibodies
    • 12429589
    • Willison HJ, Yuki N (2002) Peripheral neuropathies and anti-glycolipid antibodies. Brain 125:2591-2625
    • (2002) Brain , vol.125 , pp. 2591-2625
    • Willison, H.J.1    Yuki, N.2
  • 6
    • 48549100652 scopus 로고    scopus 로고
    • Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease - A review
    • 10.1194/jlr.R800007-JLR200 2386904 1:CAS:528:DC%2BD1cXmslWntL4%3D 18334715
    • Ariga T, McDonald MP, Yu RK (2008) Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease - a review. J Lipid Res 49:1157-1175. doi: 10.1194/jlr.R800007-JLR200
    • (2008) J Lipid Res , vol.49 , pp. 1157-1175
    • Ariga, T.1    McDonald, M.P.2    Yu, R.K.3
  • 7
    • 84879143450 scopus 로고    scopus 로고
    • Gangliosides and gangliosidoses: Principles of molecular and metabolic pathogenesis
    • 10.1523/JNEUROSCI.0822-13.2013 1:CAS:528:DC%2BC3sXhtVWmsbbJ 23785136
    • Sandhoff K, Harzer K (2013) Gangliosides and gangliosidoses: principles of molecular and metabolic pathogenesis. J Neurosci 33:10195-10208. doi: 10.1523/JNEUROSCI.0822-13.2013
    • (2013) J Neurosci , vol.33 , pp. 10195-10208
    • Sandhoff, K.1    Harzer, K.2
  • 8
    • 84886382263 scopus 로고    scopus 로고
    • The role of gangliosides in brain development and the potential benefits of perinatal supplementation
    • 10.1016/j.nutres.2013.07.021 1:CAS:528:DC%2BC3sXhsVSksLjL 24176227
    • Ryan JM, Rice GE, Mitchell MD (2013) The role of gangliosides in brain development and the potential benefits of perinatal supplementation. Nutr Res 33:877-887. doi: 10.1016/j.nutres.2013.07.021
    • (2013) Nutr Res , vol.33 , pp. 877-887
    • Ryan, J.M.1    Rice, G.E.2    Mitchell, M.D.3
  • 9
    • 80755190106 scopus 로고    scopus 로고
    • Regulatory mechanisms of nervous systems with glycosphingolipids
    • 10.1007/s11064-011-0494-2 1:CAS:528:DC%2BC3MXlvFWgt7w%3D 21562747
    • Furukawa K, Ohmi Y, Ohkawa Y, Tokuda N, Kondo Y, Tajima O, Furukawa K (2011) Regulatory mechanisms of nervous systems with glycosphingolipids. Neurochem Res 36:1578-1586. doi: 10.1007/s11064-011-0494-2
    • (2011) Neurochem Res , vol.36 , pp. 1578-1586
    • Furukawa, K.1    Ohmi, Y.2    Ohkawa, Y.3    Tokuda, N.4    Kondo, Y.5    Tajima, O.6    Furukawa, K.7
  • 10
    • 79851474972 scopus 로고    scopus 로고
    • Gangliosides are essential in the protection of inflammation and neurodegeneration via maintenance of lipid rafts: Elucidation by a series of ganglioside-deficient mutant mice
    • 10.1111/j.1471-4159.2010.07067.x 1:CAS:528:DC%2BC3MXjt1amtbs%3D 21214571
    • Ohmi Y, Tajima O, Ohkawa Y, Yamauchi Y, Sugiura Y, Furukawa K, Furukawa K (2011) Gangliosides are essential in the protection of inflammation and neurodegeneration via maintenance of lipid rafts: elucidation by a series of ganglioside-deficient mutant mice. J Neurochem 116:926-935. doi: 10.1111/j.1471-4159.2010.07067.x
    • (2011) J Neurochem , vol.116 , pp. 926-935
    • Ohmi, Y.1    Tajima, O.2    Ohkawa, Y.3    Yamauchi, Y.4    Sugiura, Y.5    Furukawa, K.6    Furukawa, K.7
  • 11
    • 58149201134 scopus 로고    scopus 로고
    • Glycosphingolipid behaviour in complex membranes
    • 10.1016/j.bbamem.2008.09.001 1:CAS:528:DC%2BD1MXksVWlsg%3D%3D 18835549
    • Prinetti A, Loberto N, Chigorno V, Sonnino S (2009) Glycosphingolipid behaviour in complex membranes. Biochim Biophys Acta 1788:184-193. doi: 10.1016/j.bbamem.2008.09.001
    • (2009) Biochim Biophys Acta , vol.1788 , pp. 184-193
    • Prinetti, A.1    Loberto, N.2    Chigorno, V.3    Sonnino, S.4
  • 12
    • 77957167810 scopus 로고    scopus 로고
    • Revitalizing membrane rafts: New tools and insights
    • 10.1038/nrm2977 1:CAS:528:DC%2BC3cXhtFylur%2FI 20861879
    • Simons K, Gerl MJ (2010) Revitalizing membrane rafts: new tools and insights. Nat Rev Mol Cell Biol 11:688-699. doi: 10.1038/nrm2977
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 688-699
    • Simons, K.1    Gerl, M.J.2
  • 13
    • 34247385150 scopus 로고    scopus 로고
    • GM1 and GM3 gangliosides highlight distinct lipid microdomains within the apical domain of epithelial cells
    • 1:CAS:528:DC%2BD2sXksV2rtr0%3D 17428477
    • Janich P, Corbeil D (2007) GM1 and GM3 gangliosides highlight distinct lipid microdomains within the apical domain of epithelial cells. FEBS Lett 581:1783-1787
    • (2007) FEBS Lett , vol.581 , pp. 1783-1787
    • Janich, P.1    Corbeil, D.2
  • 14
    • 34247184670 scopus 로고    scopus 로고
    • Ganglioside GM2-tetraspanin CD82 complex inhibits met and its cross-talk with integrins, providing a basis for control of cell motility through glycosynapse
    • 1:CAS:528:DC%2BD2sXis1KgtL8%3D 17215249
    • Todeschini AR, Dos Santos JN, Handa K, Hakomori SI (2007) Ganglioside GM2-tetraspanin CD82 complex inhibits met and its cross-talk with integrins, providing a basis for control of cell motility through glycosynapse. J Biol Chem 282:8123-8133
    • (2007) J Biol Chem , vol.282 , pp. 8123-8133
    • Todeschini, A.R.1    Dos Santos, J.N.2    Handa, K.3    Hakomori, S.I.4
  • 15
    • 70349871692 scopus 로고    scopus 로고
    • Gangliosides in cell recognition and membrane protein regulation
    • 10.1016/j.sbi.2009.06.001 2763983 1:CAS:528:DC%2BD1MXht1ylsL3N 19608407
    • Lopez PH, Schnaar RL (2009) Gangliosides in cell recognition and membrane protein regulation. Curr Opin Struct Biol 19:549-557. doi: 10.1016/j.sbi.2009.06.001
    • (2009) Curr Opin Struct Biol , vol.19 , pp. 549-557
    • Lopez, P.H.1    Schnaar, R.L.2
  • 18
    • 40749132024 scopus 로고    scopus 로고
    • Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains
    • 2312458
    • Todeschini AR, Hakomori SI (2008) Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains. Biochim Biophys Acta 1780:421-433
    • (2008) Biochim Biophys Acta , vol.1780 , pp. 421-433
    • Todeschini, A.R.1    Hakomori, S.I.2
  • 19
    • 0020003718 scopus 로고
    • GD3, a prominent ganglioside of human melanoma. Detection and characterisation by mouse monoclonal antibody
    • 1:CAS:528:DyaL38Xhs1Smsbs%3D 7061953
    • Pukel CS, Lloyd KO, Travassos LR, Dippold WG, Oettgen HF, Old LJ (1982) GD3, a prominent ganglioside of human melanoma. Detection and characterisation by mouse monoclonal antibody. J Exp Med 155:1133-1147
    • (1982) J Exp Med , vol.155 , pp. 1133-1147
    • Pukel, C.S.1    Lloyd, K.O.2    Travassos, L.R.3    Dippold, W.G.4    Oettgen, H.F.5    Old, L.J.6
  • 21
    • 23944472365 scopus 로고    scopus 로고
    • Selection of GM2, fucosyl GM1, globo H and polysialic acid as targets on small cell lung cancers for antibody mediated immunotherapy
    • 1:CAS:528:DC%2BD2MXntVeht74%3D 15926079
    • Livingston PO, Hood C, Krug LM, Warren N, Kris MG, Brezicka T, Ragupathi G (2005) Selection of GM2, fucosyl GM1, globo H and polysialic acid as targets on small cell lung cancers for antibody mediated immunotherapy. Cancer Immunol Immunother 54:1018-1025
    • (2005) Cancer Immunol Immunother , vol.54 , pp. 1018-1025
    • Livingston, P.O.1    Hood, C.2    Krug, L.M.3    Warren, N.4    Kris, M.G.5    Brezicka, T.6    Ragupathi, G.7
  • 25
    • 19544387400 scopus 로고    scopus 로고
    • Low complex ganglioside expression characterizes human neuroblastoma cell lines
    • 2866625 1:CAS:528:DC%2BD2MXks1GgsLo%3D 15922866
    • Hettmer S, Ladisch S, Kaucic K (2005) Low complex ganglioside expression characterizes human neuroblastoma cell lines. Cancer Lett 225:141-149
    • (2005) Cancer Lett , vol.225 , pp. 141-149
    • Hettmer, S.1    Ladisch, S.2    Kaucic, K.3
  • 26
    • 3843114549 scopus 로고    scopus 로고
    • Alterations in neuroblastoma ganglioside synthesis by induction of GD1b synthase by retinoic acid
    • 2409816 1:CAS:528:DC%2BD2cXls1ehsbY%3D 15187999
    • Hettmer S, McCarter R, Ladisch S, Kaucic K (2004) Alterations in neuroblastoma ganglioside synthesis by induction of GD1b synthase by retinoic acid. Br J Cancer 91:389-397
    • (2004) Br J Cancer , vol.91 , pp. 389-397
    • Hettmer, S.1    McCarter, R.2    Ladisch, S.3    Kaucic, K.4
  • 27
    • 0038532523 scopus 로고    scopus 로고
    • Role of tumor-associated gangliosides in cancer progression
    • 12770784
    • Birklé S, Zeng G, Gao L, Yu RK, Aubry J (2003) Role of tumor-associated gangliosides in cancer progression. Biochimie 85:455-463
    • (2003) Biochimie , vol.85 , pp. 455-463
    • Birklé, S.1    Zeng, G.2    Gao, L.3    Yu, R.K.4    Aubry, J.5
  • 28
    • 84865713189 scopus 로고    scopus 로고
    • Enhancement of malignant properties of human osteosarcoma cells with disialyl gangliosides GD2/GD3
    • 10.1111/j.1349-7006.2012.02344.x 1:CAS:528:DC%2BC38Xht1ymt7vJ 22632091
    • Shibuya H, Hamamura K, Hotta H, Matsumoto Y, Nishida Y, Hattori H, Furukawa K, Ueda M, Furukawa K (2012) Enhancement of malignant properties of human osteosarcoma cells with disialyl gangliosides GD2/GD3. Cancer Sci 103:1656-1664. doi: 10.1111/j.1349-7006.2012.02344.x
    • (2012) Cancer Sci , vol.103 , pp. 1656-1664
    • Shibuya, H.1    Hamamura, K.2    Hotta, H.3    Matsumoto, Y.4    Nishida, Y.5    Hattori, H.6    Furukawa, K.7    Ueda, M.8    Furukawa, K.9
  • 29
    • 84879283785 scopus 로고    scopus 로고
    • Deacetylated GM3 promotes uPAR-associated membrane molecular complex to activate p38 MAPK in metastatic melanoma
    • 10.1158/1541-7786.MCR-12-0270-T 1:CAS:528:DC%2BC3sXpsVykt7k%3D 23525268
    • Yan Q, Bach DQ, Gatla N, Sun P, Liu JW, Lu JY, Paller AS, Wang XQ (2013) Deacetylated GM3 promotes uPAR-associated membrane molecular complex to activate p38 MAPK in metastatic melanoma. Mol Cancer Res 11:665-675. doi: 10.1158/1541-7786.MCR-12-0270-T
    • (2013) Mol Cancer Res , vol.11 , pp. 665-675
    • Yan, Q.1    Bach, D.Q.2    Gatla, N.3    Sun, P.4    Liu, J.W.5    Lu, J.Y.6    Paller, A.S.7    Wang, X.Q.8
  • 30
    • 84866536027 scopus 로고    scopus 로고
    • Ganglioside inhibition of CD8+ T cell cytotoxicity: Interference with lytic granule trafficking and exocytosis
    • 1:CAS:528:DC%2BC38XhtlOmurfE 22956583
    • Lee HC, Wondimu A, Liu Y, Ma JS, Radoja S, Ladisch S (2012) Ganglioside inhibition of CD8+ T cell cytotoxicity: interference with lytic granule trafficking and exocytosis. J Immunol 189:3521-3527
    • (2012) J Immunol , vol.189 , pp. 3521-3527
    • Lee, H.C.1    Wondimu, A.2    Liu, Y.3    Ma, J.S.4    Radoja, S.5    Ladisch, S.6
  • 31
    • 84907495445 scopus 로고    scopus 로고
    • Gangliosides drive the tumor infiltration and function of myeloid-derived suppressor cells
    • 10.1158/0008-5472.CAN-14-0927 1:CAS:528:DC%2BC2cXhs1GnsbnI 25115301
    • Wondimu A, Liu Y, Su Y, Bobb D, Ma JS, Chakrabarti L, Radoja S, Ladisch S (2014) Gangliosides drive the tumor infiltration and function of myeloid-derived suppressor cells. Cancer Res 74:5449-5457. doi: 10.1158/0008-5472.CAN-14-0927
    • (2014) Cancer Res , vol.74 , pp. 5449-5457
    • Wondimu, A.1    Liu, Y.2    Su, Y.3    Bobb, D.4    Ma, J.S.5    Chakrabarti, L.6    Radoja, S.7    Ladisch, S.8
  • 32
    • 84903906267 scopus 로고    scopus 로고
    • Tumor gangliosides accelerate murine tumor angiogenesis
    • 10.1007/s10456-013-9403-4 24165965
    • Liu Y, Wondimu A, Yan S, Bobb D, Ladisch S (2014) Tumor gangliosides accelerate murine tumor angiogenesis. Angiogenesis 17:563-571. doi: 10.1007/s10456-013-9403-4
    • (2014) Angiogenesis , vol.17 , pp. 563-571
    • Liu, Y.1    Wondimu, A.2    Yan, S.3    Bobb, D.4    Ladisch, S.5
  • 34
    • 84892369775 scopus 로고    scopus 로고
    • Engineering anti-GD2 monoclonal antibodies for cancer immunotherapy
    • 10.1016/j.febslet.2013.11.030 1:CAS:528:DC%2BC3sXhvFOgsbzJ 24295643
    • Ahmed M, Cheung NK (2014) Engineering anti-GD2 monoclonal antibodies for cancer immunotherapy. FEBS Lett 588:288-297. doi: 10.1016/j.febslet.2013.11.030
    • (2014) FEBS Lett , vol.588 , pp. 288-297
    • Ahmed, M.1    Cheung, N.K.2
  • 35
    • 84892411944 scopus 로고    scopus 로고
    • Glycosylation of glycolipids in cancer: Basis for development of novel therapeutic approaches
    • 10.3389/fonc.2013.00306 3867695 24392350
    • Daniotti JL, Vilcaes AA, Torres Demichelis V, Ruggiero FM, Rodriguez-Walker M (2013) Glycosylation of glycolipids in cancer: basis for development of novel therapeutic approaches. Front Oncol 3:306. doi: 10.3389/fonc.2013.00306
    • (2013) Front Oncol , vol.3 , pp. 306
    • Daniotti, J.L.1    Vilcaes, A.A.2    Torres Demichelis, V.3    Ruggiero, F.M.4    Rodriguez-Walker, M.5
  • 36
    • 84890741977 scopus 로고    scopus 로고
    • Anti-ganglioside anti-idiotypic vaccination: More than molecular mimicry
    • 3501824 23181219
    • Vázquez AM, Rodrèguez-Zhurbenko N, López AM (2012) Anti-ganglioside anti-idiotypic vaccination: more than molecular mimicry. Front Oncol 2:170. doi: 10.3389/fonc.2012.00170
    • (2012) Front Oncol , vol.2 , pp. 170
    • Vázquez, A.M.1    Rodrèguez-Zhurbenko, N.2    López, A.M.3
  • 37
    • 84939989991 scopus 로고    scopus 로고
    • Application of molecular mimicry to target GD2 ganglioside
    • Shimada H (ed), InTech, Rijeka
    • Horwacik I, Rokita H (2012) Application of molecular mimicry to target GD2 ganglioside. In: Shimada H (ed) Neuroblastoma - present and future, InTech, Rijeka, pp. 251-271. doi: 10.5772/30020
    • (2012) Neuroblastoma - Present and Future , pp. 251-271
    • Horwacik, I.1    Rokita, H.2
  • 40
    • 0032720632 scopus 로고    scopus 로고
    • Apoptosis induction of human lung cancer cell line in multicellular heterospheroids with humanized antiganglioside GM2 monoclonal antibody
    • 1:CAS:528:DyaK1MXmvFeltr8%3D 10537316
    • Nakamura K, Hanibuchi M, Yano S, Tanaka Y, Fujino I, Inoue M, Takezawa T, Shitara K, Sone S, Hanai N (1999) Apoptosis induction of human lung cancer cell line in multicellular heterospheroids with humanized antiganglioside GM2 monoclonal antibody. Cancer Res 59:5323-5330
    • (1999) Cancer Res , vol.59 , pp. 5323-5330
    • Nakamura, K.1    Hanibuchi, M.2    Yano, S.3    Tanaka, Y.4    Fujino, I.5    Inoue, M.6    Takezawa, T.7    Shitara, K.8    Sone, S.9    Hanai, N.10
  • 42
    • 0021330449 scopus 로고
    • Inhibition of human melanoma cell growth in vitro by monoclonal anti-GD3-ganglioside antibody
    • 1:CAS:528:DyaL2cXotl2gug%3D%3D 6362854
    • Dippold WG, Knuth A, Meyer zum Büschenfelde KH (1984) Inhibition of human melanoma cell growth in vitro by monoclonal anti-GD3-ganglioside antibody. Cancer Res 44:806-810
    • (1984) Cancer Res , vol.44 , pp. 806-810
    • Dippold, W.G.1    Knuth, A.2    Meyer Zum Büschenfelde, K.H.3
  • 43
    • 0035872467 scopus 로고    scopus 로고
    • Ganglioside G(D2) in small cell lung cancer cell lines: Enhancement of cell proliferation and mediation of apoptosis
    • 1:CAS:528:DC%2BD3MXktVWqtLk%3D 11358851
    • Yoshida S, Fukumoto S, Kawaguchi H, Sato S, Ueda R, Furukawa K (2001) Ganglioside G(D2) in small cell lung cancer cell lines: enhancement of cell proliferation and mediation of apoptosis. Cancer Res 61(10):4244-4252
    • (2001) Cancer Res , vol.61 , Issue.10 , pp. 4244-4252
    • Yoshida, S.1    Fukumoto, S.2    Kawaguchi, H.3    Sato, S.4    Ueda, R.5    Furukawa, K.6
  • 44
    • 67349260735 scopus 로고    scopus 로고
    • The GD2-specific 14G2a monoclonal antibody induces apoptosis and enhances cytotoxicity of chemotherapeutic drugs in IMR-32 human neuroblastoma cells
    • 10.1016/j.canlet.2009.02.040 1:CAS:528:DC%2BD1MXnsFajs7g%3D 19339105
    • Kowalczyk A, Gil M, Horwacik I, Odrowaz Z, Kozbor D, Rokita H (2009) The GD2-specific 14G2a monoclonal antibody induces apoptosis and enhances cytotoxicity of chemotherapeutic drugs in IMR-32 human neuroblastoma cells. Cancer Lett 281:171-182. doi: 10.1016/j.canlet.2009.02.040
    • (2009) Cancer Lett , vol.281 , pp. 171-182
    • Kowalczyk, A.1    Gil, M.2    Horwacik, I.3    Odrowaz, Z.4    Kozbor, D.5    Rokita, H.6
  • 45
    • 84887137092 scopus 로고    scopus 로고
    • Targeting GD2 ganglioside and aurora A kinase as a dual strategy leading to cell death in cultures of human neuroblastoma cells
    • 10.1016/j.canlet.2013.08.018 1:CAS:528:DC%2BC3sXhtl2ru7fL 23962557
    • Horwacik I, Durbas M, Boratyn E, Wȩgrzyn P, Rokita H (2013) Targeting GD2 ganglioside and aurora A kinase as a dual strategy leading to cell death in cultures of human neuroblastoma cells. Cancer Lett 341:248-264. doi: 10.1016/j.canlet.2013.08.018
    • (2013) Cancer Lett , vol.341 , pp. 248-264
    • Horwacik, I.1    Durbas, M.2    Boratyn, E.3    Wȩgrzyn, P.4    Rokita, H.5
  • 46
    • 84876724408 scopus 로고    scopus 로고
    • Cell cycle arrest and apoptosis induced by O-acetyl-GD2-specific monoclonal antibody 8B6 inhibits tumor growth in vitro and in vivo
    • 10.1016/j.canlet.2013.01.032 1:CAS:528:DC%2BC3sXisVOgsrs%3D 23370223
    • Cochonneau D, Terme M, Michaud A, Dorvillius M, Gautier N, Frikeche J, Alvarez-Rueda N, Bougras G, Aubry J, Paris F, Birklé S (2013) Cell cycle arrest and apoptosis induced by O-acetyl-GD2-specific monoclonal antibody 8B6 inhibits tumor growth in vitro and in vivo. Cancer Lett 333:194-204. doi: 10.1016/j.canlet.2013.01.032
    • (2013) Cancer Lett , vol.333 , pp. 194-204
    • Cochonneau, D.1    Terme, M.2    Michaud, A.3    Dorvillius, M.4    Gautier, N.5    Frikeche, J.6    Alvarez-Rueda, N.7    Bougras, G.8    Aubry, J.9    Paris, F.10    Birklé, S.11
  • 47
    • 0034445003 scopus 로고    scopus 로고
    • Monoclonal anti-GD3 antibodies selectively inhibit the proliferation of human malignant glioma cells in vitro
    • 1:CAS:528:DC%2BD3MXkt1Cgu7w%3D 11425192
    • Hedberg KM, Dellheden B, Wikstrand CJ, Fredman P (2000) Monoclonal anti-GD3 antibodies selectively inhibit the proliferation of human malignant glioma cells in vitro. Glycoconj J 17:717-726
    • (2000) Glycoconj J , vol.17 , pp. 717-726
    • Hedberg, K.M.1    Dellheden, B.2    Wikstrand, C.J.3    Fredman, P.4
  • 48
    • 84899627450 scopus 로고    scopus 로고
    • Endothelin A receptor antagonism enhances inhibitory effects of anti-ganglioside GD2 monoclonal antibody on invasiveness and viability of human osteosarcoma cells
    • 10.1371/journal.pone.0093576 3984094 24727660
    • Liu B, Wu Y, Zhou Y, Peng D (2014) Endothelin A receptor antagonism enhances inhibitory effects of anti-ganglioside GD2 monoclonal antibody on invasiveness and viability of human osteosarcoma cells. PLoS ONE 9:e93576. doi: 10.1371/journal.pone.0093576
    • (2014) PLoS ONE , vol.9 , pp. e93576
    • Liu, B.1    Wu, Y.2    Zhou, Y.3    Peng, D.4
  • 49
    • 22244491314 scopus 로고    scopus 로고
    • Characterization of a proapoptotic antiganglioside GM2 monoclonal antibody and evaluation of its therapeutic effect on melanoma and small cell lung carcinoma xenografts
    • 1:CAS:528:DC%2BD2MXmt1egtLc%3D 16024647
    • Retter MW, Johnson JC, Peckham DW, Bannink JE, Bangur CS, Dresser K, Cai F, Foy TM, Fanger NA, Fanger GR, Woda B, Rock KL (2005) Characterization of a proapoptotic antiganglioside GM2 monoclonal antibody and evaluation of its therapeutic effect on melanoma and small cell lung carcinoma xenografts. Cancer Res 65:6425-6434
    • (2005) Cancer Res , vol.65 , pp. 6425-6434
    • Retter, M.W.1    Johnson, J.C.2    Peckham, D.W.3    Bannink, J.E.4    Bangur, C.S.5    Dresser, K.6    Cai, F.7    Foy, T.M.8    Fanger, N.A.9    Fanger, G.R.10    Woda, B.11    Rock, K.L.12
  • 51
    • 23844455213 scopus 로고    scopus 로고
    • Mechanisms for the apoptosis of small cell lung cancer cells induced by anti-GD2 monoclonal antibodies: Roles of anoikis
    • 1:CAS:528:DC%2BD2MXns1Slt78%3D 15923178
    • Aixinjueluo W, Furukawa K, Zhang Q, Hamamura K, Tokuda N, Yoshida S, Ueda R, Furukawa K (2005) Mechanisms for the apoptosis of small cell lung cancer cells induced by anti-GD2 monoclonal antibodies: roles of anoikis. J Biol Chem 280:29828-29836
    • (2005) J Biol Chem , vol.280 , pp. 29828-29836
    • Aixinjueluo, W.1    Furukawa, K.2    Zhang, Q.3    Hamamura, K.4    Tokuda, N.5    Yoshida, S.6    Ueda, R.7    Furukawa, K.8
  • 52
    • 78649657624 scopus 로고    scopus 로고
    • GD3 synthase expression enhances proliferation and tumor growth of MDA-MB-231 breast cancer cells through c-Met activation
    • 10.1158/1541-7786.MCR-10-0302 1:CAS:528:DC%2BC3cXhsVOktLbK 20889649
    • Cazet A, Lefebvre J, Adriaenssens E, Julien S, Bobowski M, Grigoriadis A, Tutt A, Tulasne D, Le Bourhis X, Delannoy P (2010) GD3 synthase expression enhances proliferation and tumor growth of MDA-MB-231 breast cancer cells through c-Met activation. Mol Cancer Res 8:1526-1535. doi: 10.1158/1541-7786.MCR-10-0302
    • (2010) Mol Cancer Res , vol.8 , pp. 1526-1535
    • Cazet, A.1    Lefebvre, J.2    Adriaenssens, E.3    Julien, S.4    Bobowski, M.5    Grigoriadis, A.6    Tutt, A.7    Tulasne, D.8    Le Bourhis, X.9    Delannoy, P.10
  • 53
    • 84860355482 scopus 로고    scopus 로고
    • The ganglioside G(D2) induces the constitutive activation of c-Met in MDA-MB-231 breast cancer cells expressing the G(D3) synthase
    • 10.1093/glycob/cws049 1:CAS:528:DC%2BC38Xmt1yntrk%3D 22301273
    • Cazet A, Bobowski M, Rombouts Y, Lefebvre J, Steenackers A, Popa I, Guérardel Y, Le Bourhis X, Tulasne D, Delannoy P (2012) The ganglioside G(D2) induces the constitutive activation of c-Met in MDA-MB-231 breast cancer cells expressing the G(D3) synthase. Glycobiology 22:806-816. doi: 10.1093/glycob/cws049
    • (2012) Glycobiology , vol.22 , pp. 806-816
    • Cazet, A.1    Bobowski, M.2    Rombouts, Y.3    Lefebvre, J.4    Steenackers, A.5    Popa, I.6    Guérardel, Y.7    Le Bourhis, X.8    Tulasne, D.9    Delannoy, P.10
  • 54
  • 56
    • 0036053357 scopus 로고    scopus 로고
    • An anti-GD2 monoclonal antibody enhances apoptotic effects of anti-cancer drugs against small cell lung cancer cells via JNK (c-Jun terminal kinase) activation
    • 1:CAS:528:DC%2BD38XmvFOlsbs%3D 12149148
    • Yoshida S, Kawaguchi H, Sato S, Ueda R, Furukawa K (2002) An anti-GD2 monoclonal antibody enhances apoptotic effects of anti-cancer drugs against small cell lung cancer cells via JNK (c-Jun terminal kinase) activation. Jpn J Cancer Res 93:816-824
    • (2002) Jpn J Cancer Res , vol.93 , pp. 816-824
    • Yoshida, S.1    Kawaguchi, H.2    Sato, S.3    Ueda, R.4    Furukawa, K.5
  • 58
    • 0029148798 scopus 로고
    • Pharmacokinetics of anti-ganglioside GD2 mAb 14G2a in a phase i trial in pediatric cancer patients
    • 1:CAS:528:DyaK2MXoslars7o%3D 7641217
    • Uttenreuther-Fischer MM, Huang CS, Reisfeld RA, Yu AL (1995) Pharmacokinetics of anti-ganglioside GD2 mAb 14G2a in a phase I trial in pediatric cancer patients. Cancer Immunol Immunother 41:29-36
    • (1995) Cancer Immunol Immunother , vol.41 , pp. 29-36
    • Uttenreuther-Fischer, M.M.1    Huang, C.S.2    Reisfeld, R.A.3    Yu, A.L.4
  • 59
    • 79952762286 scopus 로고    scopus 로고
    • Successful multifold dose escalation of anti-GD2 monoclonal antibody 3F8 in patients with neuroblastoma: A phase i study
    • 10.1200/JCO.2010.28.3317 3083872 1:CAS:528:DC%2BC3MXmtVyrsL8%3D 21343563
    • Kushner BH, Kramer K, Modak S, Cheung NK (2011) Successful multifold dose escalation of anti-GD2 monoclonal antibody 3F8 in patients with neuroblastoma: a phase I study. J Clin Oncol 29:1168-1174. doi: 10.1200/JCO.2010.28.3317
    • (2011) J Clin Oncol , vol.29 , pp. 1168-1174
    • Kushner, B.H.1    Kramer, K.2    Modak, S.3    Cheung, N.K.4
  • 60
    • 58149329110 scopus 로고    scopus 로고
    • Phase I study of ch14.18 with granulocyte-macrophage colony-stimulating factor and interleukin-2 in children with neuroblastoma after autologous bone marrow transplantation or stem-cell rescue: A report from the Children's Oncology Group
    • 10.1200/JCO.2006.10.3564 2645092 1:CAS:528:DC%2BD1MXhs1Gnsb0%3D 19047298
    • Gilman AL, Ozkaynak MF, Matthay KK, Krailo M, Yu AL, Gan J, Sternberg A, Hank JA, Seeger R, Reaman GH, Sondel PM (2009) Phase I study of ch14.18 with granulocyte-macrophage colony-stimulating factor and interleukin-2 in children with neuroblastoma after autologous bone marrow transplantation or stem-cell rescue: a report from the Children's Oncology Group. J Clin Oncol 27:85-91. doi: 10.1200/JCO.2006.10.3564
    • (2009) J Clin Oncol , vol.27 , pp. 85-91
    • Gilman, A.L.1    Ozkaynak, M.F.2    Matthay, K.K.3    Krailo, M.4    Yu, A.L.5    Gan, J.6    Sternberg, A.7    Hank, J.A.8    Seeger, R.9    Reaman, G.H.10    Sondel, P.M.11
  • 62
    • 79953180541 scopus 로고    scopus 로고
    • Anti-NeuGcGM3 antibodies, actively elicited by idiotypic vaccination in nonsmall cell lung cancer patients, induce tumor cell death by an oncosis-like mechanism
    • 10.4049/jimmunol.1000609 21300821
    • Hernández AM, Rodríguez N, González JE, Reyes E, Rondón T, Griñán T, Macías A, Alfonso S, Vázquez AM, Pérez R (2011) Anti-NeuGcGM3 antibodies, actively elicited by idiotypic vaccination in nonsmall cell lung cancer patients, induce tumor cell death by an oncosis-like mechanism. J Immunol 186:3735-3744. doi: 10.4049/jimmunol.1000609
    • (2011) J Immunol , vol.186 , pp. 3735-3744
    • Hernández, A.M.1    Rodríguez, N.2    González, J.E.3    Reyes, E.4    Rondón, T.5    Griñán, T.6    Macías, A.7    Alfonso, S.8    Vázquez, A.M.9    Pérez, R.10


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