Mg++ requirement for MtHK binding, and Mg++ stabilization of mitochondrial membranes via activation of MtHK & MtCK and promotion of mitochondrial permeability transition pore closure: A hypothesis on mechanisms underlying Mg++'s antioxidant and cytoprotective effects

Gene

Volumn 581, Issue 1, 2016, Pages 1-13

  Golshani Hebroni, Shiva ^a  

^a NONE

Author keywords

Anti apoptosis; Anti necrosis; Antioxidant; Apoptosis; ATP synthase; Calcium; Cardioprotection; Cytoprotection; Degenerative disease; Hexokinase; Magnesium; Mitochondrial bound hexokinase; Mitochondrial creatine kinase; Mitochondrial permeability transition pore; Necrosis; Neuroprotection

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; ANTIOXIDANT; CALCIUM ION; EXCITATORY AMINO ACID; HEXOKINASE; MAGNESIUM ION; MITOCHONDRIAL CREATINE KINASE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOCHONDRION BOUND HEXOKINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL; CALCIUM; CARRIER PROTEIN; CREATINE KINASE; MAGNESIUM; PROTEIN BINDING;

ALLOSTERISM; APOPTOSIS; CELL DAMAGE; CELL LOSS; CELL PROLIFERATION; CELL PROTECTION; CELL STIMULATION; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; HUMAN; ISCHEMIC PRECONDITIONING; MEMBRANE STABILIZATION; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL PERMEABILITY; NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REVIEW; ANIMAL; COLD; ENZYMOLOGY; METABOLISM;

ANIMALS; ANTIOXIDANTS; CALCIUM; COLD TEMPERATURE; CREATINE KINASE; ENZYME ACTIVATION; HEXOKINASE; MAGNESIUM; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL MEMBRANES; PROTEIN BINDING;

EID: 84958053544     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2015.12.046     Document Type: Review

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