TRPM7: A unique channel involved in magnesium homeostasis

International Journal of Biochemistry and Cell Biology

Volumn 44, Issue 8, 2012, Pages 1381-1384

  Paravicini, Tamara M ^a   Chubanov, Vladimir ^b   Gudermann, Thomas ^b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Alpha kinase; Magnesium; Transient receptor potential; TRPM7

Indexed keywords

LIPOCORTIN 1; MAGNESIUM ION; MYOSIN IIA; TRANSIENT RECEPTOR POTENTIAL CHANNEL M7;

CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; EMBRYO DEVELOPMENT; MAGNESIUM METABOLISM; REVIEW;

EID: 84861927907     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2012.05.010     Document Type: Short Survey

References (30)

1. Aarts M, Iihara K, Wei WL, Xiong ZG, Arundine M, Cerwinski W, et al. A key role for TRPM7 channels in anoxic neuronal death. Cell 2003;115:863-77. (Pubitemid 38058498)
2. 2+ transporter transient receptor potential melastatin 7 (TRPM7) cation channel by Bradykinin in vascular smooth muscle cells. Journal of Hypertension 2009;27:155-66.
3. Ca2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7. British Journal of Pharmacology 2012;166:1357-76.
4. Clark K, Middelbeek J, Lasonder E, Dulyaninova NG, Morrice NA, Ryazanov AG, et al. TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation. Journal of Molecular Biology 2008a;378:790-803.
5. Clark K, Middelbeek J, Morrice NA, Figdor CG, Lasonder E, van Leeuwen FN. Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7. PLoS One 2008b;3:e1876.
6. 2+ uptake in cells lacking the channel-kinase TRPM7. FEBS Letters 2011;585:2275-8.
7. Dorovkov MV, Ryazanov AG. Phosphorylation of annexin I by TRPM7 channel-kinase. Journal of Biological Chemistry 2004;279:50643-6. (Pubitemid 40017798)
8. 2+ signals confer fibrogenesis in human atrial fibrillation. Circulation Research 2010;106:992-1003.
9. Gwanyanya A, Sipido KR, Vereecke J, Mubagwa K. ATP and PIP2 dependence of the magnesium-inhibited, TRPM7-like cation channel in cardiac myocytes. American Journal of Physiology - Cell Physiology 2006;291: C627-35. (Pubitemid 44497589)
10. He Y, Yao G, Savoia C, Touyz RM. Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II. Circulation Research 2005;96:207-15. (Pubitemid 40209368)
11. Hermosura MC, Nayakanti H, Dorovkov MV, Calderon FR, Ryazanov AG, Haymer DS, et al. A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two guamanian neurodegenerative disorders. Proceedings of the National Academy of Science of the United States of America 2005;102:11510-5.
12. 2+ homeostasis. Science 2008;322:756-60.
13. Jin J, Wu LJ, Jun J, Cheng X, Xu H, Andrews NC, et al. The channel kinase, TRPM7, is required for early embryonic development. Proceedings of the National Academy of Sciences of the United States of America 2012;109:E225-33.
14. Landman N, Jeong SY, Shin SY, Voronov SV, Serban G, Kang MS, et al. Presenilin mutations linked to familial Alzheimer's disease cause an imbalance in phosphatidylinositol 4,5-bisphosphate metabolism. Proceedings of the National Academy of Sciences of the United States of America 2006;103:19524-9. (Pubitemid 46026064)
15. Langeslag M, Clark K, Moolenaar WH, van Leeuwen FN, Jalink K. Activation of TRPM7 channels by phospholipase C-coupled receptor agonists. Journal of Biological Chemistry 2007;282:232-9. (Pubitemid 47076646)
16. 2+ permeability and pH sensitivity in TRPM6 and TRPM7. Journal of Biological Chemistry 2007;282: 25817-30.
17. Liu W, Su LT, Khadka DK, Mezzacappa C, Komiya Y, Sato A, et al. TRPM7 regulates gastrulation during vertebrate embryogenesis. Developmental Biology 2011;350:348-57.
18. Mederos y Schnitzler M, Wäring J, Gudermann T, Chubanov V. Evolutionary determinants of divergent calcium selectivity of TRPM channels. FASEB Journal 2008;22:1540-51.
19. Nadler MJ, Hermosura MC, Inabe K, Perraud AL, Zhu Q, Stokes AJ, et al. LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability. Nature 2001;411:590-5. (Pubitemid 32531406)
20. Perraud AL, Zhao X, Ryazanov AG, Schmitz C. The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-K. Cellular Signalling 2011;23:586-93.
21. Runnels LW, Yue L, Clapham DE. TRP-PLIK, a bifunctional protein with kinase and ion channel activities. Science 2001;291:1043-7. (Pubitemid 32157413)
22. 2 hydrolysis. Nature Cell Biology 2002;4:329-36.
23. 2+ homeostasis in mammals. Nature Communication 2010;1:109.
24. 2+transporter. Biochemical Journal 2007;401:505-13.
25. Schlingmann KP, Waldegger S, Konrad M, Chubanov V, Gudermann T. TRPM6 and TRPM7 - gatekeepers of human magnesium metabolism. Biochimica et Biophysica Acta 2007;1772:813-21.
26. 2+ homeostasis by TRPM7. Cell 2003;114:191-200.
27. Su LT, Chen HC, González-Pagán O, Overton JD, Xie J, Yue L, et al. TRPM7 activates m-calpain by stress-dependent stimulation of p38 MAPK and c-Jun N-terminal kinase. Journal of Molecular Biology 2010;396:858-69.
28. Sun HS, Jackson MF, Martin LJ, Jansen K, Teves L, Cui H, et al. Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia. Nature Neuroscience 2009;12: 1300-7.
29. Yamaguchi H, Matsushita M, Nairn AC, Kuriyan J. Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity. Molecular Cell 2001;7:1047-57. (Pubitemid 32525751)
30. Zierler S, Yao G, Zhang Z, Kuo WC, Pörzgen P, Penner R, et al. Waixenicin A inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channels. Journal of Biological Chemistry 2011;286:39328-35.