메뉴 건너뛰기




Volumn 123, Issue 11, 2010, Pages 1447-1452

Role of PI3K/Akt signaling in the protective effect of magnesium sulfate against ischemia-perfusion injury of small intestine in rats

Author keywords

Apoptosis; Intestinal mucosa; Magnesium sulfate; Oxidative stress; PI3K Akt signal pathway; Reperfusion

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; AMINE OXIDASE (COPPER CONTAINING); MAGNESIUM SULFATE; MALONALDEHYDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

EID: 77953526790     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2010.11.018     Document Type: Article
Times cited : (17)

References (31)
  • 1
    • 0037237222 scopus 로고    scopus 로고
    • Hypothermia throughout intestinal ischaemia-reperfusion injury attenuates lung neutrophil infiltration
    • Vinardi S, Pierro A, Parkinson EJ, Vejchapipat P, Stefanutti G, Spitz L, et al. Hypothermia throughout intestinal ischaemia-reperfusion injury attenuates lung neutrophil infiltration. J Pediatr Surg 2003; 38: 88-91.
    • (2003) J Pediatr Surg , vol.38 , pp. 88-91
    • Vinardi, S.1    Pierro, A.2    Parkinson, E.J.3    Vejchapipat, P.4    Stefanutti, G.5    Spitz, L.6
  • 5
    • 0141958067 scopus 로고    scopus 로고
    • Splenectomy attenuates intestinal ischemia reperfusion induced acute lung injury
    • Savas C, Ozguner M, Ozguner IF, Delibas N. Splenectomy attenuates intestinal ischemia reperfusion induced acute lung injury. J Paediatr Surg 2003; 38:1465-1470.
    • (2003) J Paediatr Surg , vol.38 , pp. 1465-1470
    • Savas, C.1    Ozguner, M.2    Ozguner, I.F.3    Delibas, N.4
  • 6
    • 0028891783 scopus 로고
    • Apoptosis, oncosis and necrosis: An overview of cell death
    • Majno G, Jotis I. Apoptosis, oncosis and necrosis: An overview of cell death. Am J Pathol 1995; 146: 3-15.
    • (1995) Am J Pathol , vol.146 , pp. 3-15
    • Majno, G.1    Jotis, I.2
  • 7
    • 0031925445 scopus 로고    scopus 로고
    • Apoptosis is a major model of cell death caused by ischaemia and ischaemia/reperfusion injury to the rat intestinal epithelium
    • Ikeda H, Suzuki Y, Koike M, Tamura J, Tong J, Nomura M, Itoh G. Apoptosis is a major model of cell death caused by ischaemia and ischaemia/reperfusion injury to the rat intestinal epithelium. Gut 1998; 42: 530-537.
    • (1998) Gut , vol.42 , pp. 530-537
    • Ikeda, H.1    Suzuki, Y.2    Koike, M.3    Tamura, J.4    Tong, J.5    Nomura, M.6    Itoh, G.7
  • 8
    • 2342539081 scopus 로고    scopus 로고
    • Increased apoptosis is specific for acute rejection in rat small bowel transplant
    • Fishbein TM, Liu J, Wang L, Li Y, Boros P. Increased apoptosis is specific for acute rejection in rat small bowel transplant. J Surg Res 2004; 119: 51-55.
    • (2004) J Surg Res , vol.119 , pp. 51-55
    • Fishbein, T.M.1    Liu, J.2    Wang, L.3    Li, Y.4    Boros, P.5
  • 9
    • 33646784031 scopus 로고    scopus 로고
    • Modulation of the phosphoinositide 3-kinase signaling pathway alters host response to sepsis, inflammation, and ischemia/reperfusion injury
    • Williams DL, Ozment-Skelton T, Li C. Modulation of the phosphoinositide 3-kinase signaling pathway alters host response to sepsis, inflammation, and ischemia/reperfusion injury. Shock 2006; 25: 432-439.
    • (2006) Shock , vol.25 , pp. 432-439
    • Williams, D.L.1    Ozment-Skelton, T.2    Li, C.3
  • 10
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley LC. The phosphoinositide 3-kinase pathway. Science 2002; 296: 1655-1657.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 11
    • 34249726705 scopus 로고    scopus 로고
    • Protective role of PI3-kinase-Akt-eNOS signalling pathway in intestinal injury associated with splanchnic artery occlusion shock
    • Roviezzo F, Cuzzocrea S, Di Lorenzo A, Brancaleone V, Mazzon E, Di Paola R, et al. Protective role of PI3-kinase-Akt-eNOS signalling pathway in intestinal injury associated with splanchnic artery occlusion shock. Br J Pharmacol 2007; 151: 377-383.
    • (2007) Br J Pharmacol , vol.151 , pp. 377-383
    • Roviezzo, F.1    Cuzzocrea, S.2    Di Lorenzo, A.3    Brancaleone, V.4    Mazzon, E.5    Di Paola, R.6
  • 12
    • 33644799024 scopus 로고    scopus 로고
    • Signal transduction pathways involved in oxidative stress-induced intestinal epithelial cell apoptosis
    • Zhou Y, Wang Q, Evers BM, Chung DH. Signal transduction pathways involved in oxidative stress-induced intestinal epithelial cell apoptosis. Pediatr Res 2005; 58: 1192-1197.
    • (2005) Pediatr Res , vol.58 , pp. 1192-1197
    • Zhou, Y.1    Wang, Q.2    Evers, B.M.3    Chung, D.H.4
  • 13
    • 77953515409 scopus 로고    scopus 로고
    • The protective role and mechanism of Dexamethasone and magnesium sulfate against ischemia-reperfusion injury in rat intestine
    • Chen YB, Chen SD, Chen SS, Xu J, Peng Y, Zhang JL, et al. The protective role and mechanism of Dexamethasone and magnesium sulfate against ischemia-reperfusion injury in rat intestine. J Acta Laboratorium Animalis Scientia Sinica (Chin) 2008; 16: 445-448.
    • (2008) J Acta Laboratorium Animalis Scientia Sinica (Chin) , vol.16 , pp. 445-448
    • Chen, Y.B.1    Chen, S.D.2    Chen, S.S.3    Xu, J.4    Peng, Y.5    Zhang, J.L.6
  • 14
    • 0029040897 scopus 로고
    • Postischemic intestinal motility in rat is inversely correlated to length of ischemia. An in vivo animal model
    • Udassin R, Eimerl D, Schiffman J, Haskel Y. Postischemic intestinal motility in rat is inversely correlated to length of ischemia. An in vivo animal model. Dig Dis Sci 1995; 40: 1035-1038.
    • (1995) Dig Dis Sci , vol.40 , pp. 1035-1038
    • Udassin, R.1    Eimerl, D.2    Schiffman, J.3    Haskel, Y.4
  • 17
    • 0036172082 scopus 로고    scopus 로고
    • Preventive effect of glutamine on intestinal barrier dysfunction induced by severe trauma
    • Li JY, Lu Y, Hu S, Sun D, Yao YM. Preventive effect of glutamine on intestinal barrier dysfunction induced by severe trauma. World J Gastroenterol 2002; 8: 168-171.
    • (2002) World J Gastroenterol , vol.8 , pp. 168-171
    • Li, J.Y.1    Lu, Y.2    Hu, S.3    Sun, D.4    Yao, Y.M.5
  • 18
    • 0037189059 scopus 로고    scopus 로고
    • Upregulation of Akt phosphorylation at the early stage of middle cerebral artery occlusion in mice
    • Shibata M, Yamawaki T, Sasaki T, Hattori H, Hamada J, Fukuuchi Y, et al. Upregulation of Akt phosphorylation at the early stage of middle cerebral artery occlusion in mice. Brain Res 2002; 942: 1-10.
    • (2002) Brain Res , vol.942 , pp. 1-10
    • Shibata, M.1    Yamawaki, T.2    Sasaki, T.3    Hattori, H.4    Hamada, J.5    Fukuuchi, Y.6
  • 19
    • 0035902451 scopus 로고    scopus 로고
    • Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo
    • Matsui T, Tao J, del Monte F, Lee KH, Li L, Picard M, et al. Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo. Circulation 2001; 104: 330-335.
    • (2001) Circulation , vol.104 , pp. 330-335
    • Matsui, T.1    Tao, J.2    del Monte, F.3    Lee, K.H.4    Li, L.5    Picard, M.6
  • 20
    • 0037318985 scopus 로고    scopus 로고
    • Significance of phosphoinositide 3-kinase pathway on ischemic preconditioning followed by ischemia reperfusion in mice liver
    • Izuishi K, Fujiwara M, Hossain MA, Usuki H, Maeta H. Significance of phosphoinositide 3-kinase pathway on ischemic preconditioning followed by ischemia reperfusion in mice liver. Transplant Proc 2003; 35: 132-133.
    • (2003) Transplant Proc , vol.35 , pp. 132-133
    • Izuishi, K.1    Fujiwara, M.2    Hossain, M.A.3    Usuki, H.4    Maeta, H.5
  • 21
    • 33749670528 scopus 로고    scopus 로고
    • Signal transduction of MEK/ERK and PI3K/Akt activation by hypoxia/reoxygenation in renal epithelial cells
    • Kwon DS, Kwon CH, Kim JH, Woo JS, Jung JS, Kim YK. Signal transduction of MEK/ERK and PI3K/Akt activation by hypoxia/reoxygenation in renal epithelial cells. Eur J Cell Biol 2006; 85: 1189-1199.
    • (2006) Eur J Cell Biol , vol.85 , pp. 1189-1199
    • Kwon, D.S.1    Kwon, C.H.2    Kim, J.H.3    Woo, J.S.4    Jung, J.S.5    Kim, Y.K.6
  • 23
    • 35349023691 scopus 로고    scopus 로고
    • Heme-oxygenase-1-induced protection against hypoxia/ reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway
    • Pachori AS, Smith A, McDonald P, Zhang L, Dzau VJ, Melo LG. Heme-oxygenase-1-induced protection against hypoxia/ reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway. J Mol Cell Cardiol 2007; 43: 580-592.
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 580-592
    • Pachori, A.S.1    Smith, A.2    McDonald, P.3    Zhang, L.4    Dzau, V.J.5    Melo, L.G.6
  • 24
    • 0141606688 scopus 로고    scopus 로고
    • Activation of phosphorylating-p38 mitogen-activated protein kinase and its relationship with localization of intestinal stem cells in rats after ischemia-reperfusion injury
    • Fu XB, Xing F, Yang YH, Sun TZ, Guo BC. Activation of phosphorylating-p38 mitogen-activated protein kinase and its relationship with localization of intestinal stem cells in rats after ischemia-reperfusion injury. World J Gastroenterol 2003; 9: 2036-2039.
    • (2003) World J Gastroenterol , vol.9 , pp. 2036-2039
    • Fu, X.B.1    Xing, F.2    Yang, Y.H.3    Sun, T.Z.4    Guo, B.C.5
  • 25
    • 1042277790 scopus 로고    scopus 로고
    • Effects of enteral supplementation with glutamine granules on intestinal mucosal barrier function in severe burned patients
    • Peng X, Yan H, You Z, Wang P, Wang S. Effects of enteral supplementation with glutamine granules on intestinal mucosal barrier function in severe burned patients. Burns 2004; 30: 135-139.
    • (2004) Burns , vol.30 , pp. 135-139
    • Peng, X.1    Yan, H.2    You, Z.3    Wang, P.4    Wang, S.5
  • 27
    • 8844284547 scopus 로고    scopus 로고
    • Correlation of plasma and tissue oxidative stresses in intra-abdominal sepsis
    • Koksal GM, Sayilgan C, Aydin S, Oz H, Uzun H. Correlation of plasma and tissue oxidative stresses in intra-abdominal sepsis. J Surg Res 2004; 122: 180-183.
    • (2004) J Surg Res , vol.122 , pp. 180-183
    • Koksal, G.M.1    Sayilgan, C.2    Aydin, S.3    Oz, H.4    Uzun, H.5
  • 28
    • 0027238046 scopus 로고
    • Oxygen radicals, lipid peroxidation, and permeability changes after intestinal ischemia and reperfusion
    • Horton JW, Walker PB. Oxygen radicals, lipid peroxidation, and permeability changes after intestinal ischemia and reperfusion. J Appl Physiol 1993; 74: 1515-1520.
    • (1993) J Appl Physiol , vol.74 , pp. 1515-1520
    • Horton, J.W.1    Walker, P.B.2
  • 29
    • 33751400340 scopus 로고    scopus 로고
    • Effect of Astragalus membranaceus injection on the activity of the intestinal mucosal mast cells after hemorrhagic shock-reperfusion in rats
    • Gan XL, Hei ZQ, Huang HQ, Chen LX, Li SR, Cai J. Effect of Astragalus membranaceus injection on the activity of the intestinal mucosal mast cells after hemorrhagic shock-reperfusion in rats. Chin Med J 2006; 119: 1892-1898.
    • (2006) Chin Med J , vol.119 , pp. 1892-1898
    • Gan, X.L.1    Hei, Z.Q.2    Huang, H.Q.3    Chen, L.X.4    Li, S.R.5    Cai, J.6
  • 30
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: Navigating downstream
    • Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream. Cell 2007; 129: 1261-1274.
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 31
    • 0034845958 scopus 로고    scopus 로고
    • PKB/Akt: A key mediator of cell proliferation, survival and insulin responses?
    • Lawlor MA, Alessi DR. PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? J Cell Sci 2001; 114(Pt 16): 2903-2910.
    • (2001) J Cell Sci , vol.114 , Issue.PART 16 , pp. 2903-2910
    • Lawlor, M.A.1    Alessi, D.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.