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Volumn 287, Issue 25, 2012, Pages 20876-20887

Increased resting intracellular calcium modulates NF-κB-dependent inducible nitric-oxide synthase gene expression in dystrophic mdx skeletal myotubes

Author keywords

[No Author keywords available]

Indexed keywords

BASAL ACTIVITIES; CHRONIC INFLAMMATION; CONSTITUTIVELY ACTIVES; DYSTROPHIN; FREE SOLUTIONS; GENETIC DISORDERS; IMMUNE CELLS; INDUCIBLE NITRIC OXIDE SYNTHASE (INOS); INFLAMMATORY GENES; INTRACELLULAR CALCIUM; MUSCLE CELL; MUSCLE WASTING; MUSCULAR DYSTROPHY; MYOTUBES; NITRIC-OXIDE SYNTHASE; NUCLEAR LOCALIZATION; OVER-EXPRESSION; REACTIVE NITROGEN SPECIES; RYANODINE RECEPTORS; SKELETAL MUSCLE CELLS; TRANSCRIPTIONAL ACTIVITY; UP-REGULATION;

EID: 84862271531     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.344929     Document Type: Article
Times cited : (72)

References (83)
  • 1
    • 0036087342 scopus 로고    scopus 로고
    • Function and genetics of dystrophin and dystrophin-related proteins in muscle
    • Blake, D. J., Weir, A., Newey, S. E., and Davies, K. E. (2002) Function and genetics of dystrophin and dystrophin-related proteins in muscle. Physiol. Rev. 82, 291-329 (Pubitemid 34654455)
    • (2002) Physiological Reviews , vol.82 , Issue.2 , pp. 291-329
    • Blake, D.J.1    Weir, A.2    Newey, S.E.3    Davies, K.E.4
  • 2
    • 0037160782 scopus 로고    scopus 로고
    • The muscular dystrophies
    • Emery, A. E. (2002) The muscular dystrophies. Lancet 359, 687-695
    • (2002) Lancet , vol.359 , pp. 687-695
    • Emery, A.E.1
  • 3
    • 0030272647 scopus 로고    scopus 로고
    • Dystroglycan: An extracellular matrix receptor linked to the cytoskeleton
    • DOI 10.1016/S0955-0674(96)80103-7
    • Henry, M. D., and Campbell, K. P. (1996) Dystroglycan. An extracellular matrix receptor linked to the cytoskeleton. Curr. Opin. Cell Biol. 8, 625-631 (Pubitemid 26381719)
    • (1996) Current Opinion in Cell Biology , vol.8 , Issue.5 , pp. 625-631
    • Henry, M.D.1    Campbell, K.P.2
  • 4
    • 0028929061 scopus 로고
    • Mechanical function of dystrophin in muscle cells
    • Pasternak, C., Wong, S., and Elson, E. L. (1995) Mechanical function of dystrophin in muscle cells. J. Cell Biol. 128, 355-361
    • (1995) J. Cell Biol. , vol.128 , pp. 355-361
    • Pasternak, C.1    Wong, S.2    Elson, E.L.3
  • 6
    • 68949143544 scopus 로고    scopus 로고
    • Immune-mediated mechanisms potentially regulate the disease time course of Duchenne muscular dystrophy and provide targets for therapeutic intervention
    • Evans, N. P., Misyak, S. A., Robertson, J. L., Bassaganya-Riera, J., and Grange, R. W. (2009) Immune-mediated mechanisms potentially regulate the disease time course of Duchenne muscular dystrophy and provide targets for therapeutic intervention. PM R 1, 755-768
    • (2009) PM R , vol.1 , pp. 755-768
    • Evans, N.P.1    Misyak, S.A.2    Robertson, J.L.3    Bassaganya-Riera, J.4    Grange, R.W.5
  • 7
    • 77953496625 scopus 로고    scopus 로고
    • The NF-κB family of transcription factors and its regulation
    • Oeckinghaus, A., and Ghosh, S. (2009) The NF-κB family of transcription factors and its regulation. Cold Spring Harbor Perspect. Biol. 1, a000034
    • (2009) Cold Spring Harbor Perspect. Biol. , vol.1
    • Oeckinghaus, A.1    Ghosh, S.2
  • 11
    • 78650027468 scopus 로고    scopus 로고
    • Inhibition of the IKK/NF-κB pathway by AAV gene transfer improves muscle regeneration in older mdx mice
    • Tang, Y., Reay, D. P., Salay, M. N., Mi, M. Y., Clemens, P. R., Guttridge, D. C., Robbins, P. D., Huard, J., and Wang, B. (2010) Inhibition of the IKK/NF-κB pathway by AAV gene transfer improves muscle regeneration in older mdx mice. Gene Ther. 17, 1476-1483
    • (2010) Gene Ther. , vol.17 , pp. 1476-1483
    • Tang, Y.1    Reay, D.P.2    Salay, M.N.3    Mi, M.Y.4    Clemens, P.R.5    Guttridge, D.C.6    Robbins, P.D.7    Huard, J.8    Wang, B.9
  • 12
    • 32644442731 scopus 로고    scopus 로고
    • Nuclear factor kappa-B blockade reduces skeletal muscle degeneration and enhances muscle function in Mdx mice
    • DOI 10.1016/j.expneurol.2005.11.021, PII S0014488605004504
    • Messina, S., Bitto, A., Aguennouz, M., Minutoli, L., Monici, M. C., Altavilla, D., Squadrito, F., and Vita, G. (2006) Nuclear factor-κB blockade reduces skeletal muscle degeneration and enhances muscle function in Mdx mice. Exp. Neurol. 198, 234-241 (Pubitemid 43243761)
    • (2006) Experimental Neurology , vol.198 , Issue.1 , pp. 234-241
    • Messina, S.1    Bitto, A.2    Aguennouz, M.3    Minutoli, L.4    Monici, M.C.5    Altavilla, D.6    Squadrito, F.7    Vita, G.8
  • 13
    • 42149174841 scopus 로고    scopus 로고
    • Protein-DNA array-based identification of transcription factor activities differentially regulated in skeletal muscle of normal and dystrophin-deficient mdx mice
    • Dogra, C., Srivastava, D. S., and Kumar, A. (2008) Protein-DNA array-based identification of transcription factor activities differentially regulated in skeletal muscle of normal and dystrophin-deficient mdx mice. Mol. Cell. Biochem. 312, 17-24
    • (2008) Mol. Cell. Biochem. , vol.312 , pp. 17-24
    • Dogra, C.1    Srivastava, D.S.2    Kumar, A.3
  • 14
    • 33748070833 scopus 로고    scopus 로고
    • Progressive nuclear factor-κB activation resistant to inhibition by contraction and curcumin in mdx mice
    • DOI 10.1002/mus.20579
    • Durham, W. J., Arbogast, S., Gerken, E., Li, Y. P., and Reid, M. B. (2006) Progressive nuclear factor-κB activation resistant to inhibition by contraction and curcumin in mdx mice. Muscle Nerve 34, 298-303 (Pubitemid 44300160)
    • (2006) Muscle and Nerve , vol.34 , Issue.3 , pp. 298-303
    • Durham, W.J.1    Arbogast, S.2    Gerken, E.3    Li, Y.-P.4    Reid, M.B.5
  • 15
    • 69549127944 scopus 로고    scopus 로고
    • Increases in nuclear p65 activation in dystrophic skeletal muscle are secondary to increases in the cellular expression of p65 and are not solely produced by increases in IκB-α kinase activity
    • Singh, R., Millman, G., Turin, E., Polisiakeiwicz, L., Lee, B., Gatti, F., Berge, J., Smith, E., Rutter, J., Sumski, C., Winders, W. T., Samadi, A., and Carlson, C. G. (2009) Increases in nuclear p65 activation in dystrophic skeletal muscle are secondary to increases in the cellular expression of p65 and are not solely produced by increases in IκB-α kinase activity. J. Neurol. Sci. 285, 159-171
    • (2009) J. Neurol. Sci. , vol.285 , pp. 159-171
    • Singh, R.1    Millman, G.2    Turin, E.3    Polisiakeiwicz, L.4    Lee, B.5    Gatti, F.6    Berge, J.7    Smith, E.8    Rutter, J.9    Sumski, C.10    Winders, W.T.11    Samadi, A.12    Carlson, C.G.13
  • 17
    • 44849127317 scopus 로고    scopus 로고
    • L-arginine decreases inflammation and modulates the nuclear factor-κB/matrix metalloproteinase cascade in Mdx muscle fibers
    • DOI 10.2353/ajpath.2008.071009
    • Hnia, K., Gayraud, J., Hugon, G., Ramonatxo, M., De La Porte, S., Matecki, S., and Mornet, D. (2008) L-Arginine decreases inflammation and modulates the nuclear factor-κB/matrix metalloproteinase cascade in mdx muscle fibers. Am. J. Pathol. 172, 1509-1519 (Pubitemid 351793345)
    • (2008) American Journal of Pathology , vol.172 , Issue.6 , pp. 1509-1519
    • Hnia, K.1    Gayraud, J.2    Hugon, G.3    Ramonatxo, M.4    De La, P.S.5    Matecki, S.6    Mornet, D.7
  • 18
    • 0037336186 scopus 로고    scopus 로고
    • Mechanical stress activates the nuclear factor-kappaB pathway in skeletal muscle fibers: A possible role in Duchenne muscular dystrophy
    • DOI 10.1096/fj.02-0542com
    • Kumar, A., and Boriek, A. M. (2003) Mechanical stress activates the nuclear factor-κB pathway in skeletal muscle fibers. A possible role in Duchenne muscular dystrophy. FASEB J. 17, 386-396 (Pubitemid 36292954)
    • (2003) FASEB Journal , vol.17 , Issue.3 , pp. 386-396
    • Kumar, A.1    Boriek, A.M.2
  • 21
    • 37849002320 scopus 로고    scopus 로고
    • Modulation of skeletal muscle antioxidant defense by exercise. Role of redox signaling
    • Ji, L. L. (2008) Modulation of skeletal muscle antioxidant defense by exercise. Role of redox signaling. Free Radic. Biol. Med. 44, 142-152
    • (2008) Free Radic. Biol. Med. , vol.44 , pp. 142-152
    • Ji, L.L.1
  • 23
    • 0035346311 scopus 로고    scopus 로고
    • iNOS expression in dystrophinopathies can be reduced by somatic gene transfer of dystrophin or utrophin
    • Louboutin, J. P., Rouger, K., Tinsley, J. M., Halldorson, J., and Wilson, J. M. (2001) iNOS expression in dystrophinopathies can be reduced by somatic gene transfer of dystrophin or utrophin. Mol. Med. 7, 355-364 (Pubitemid 33701985)
    • (2001) Molecular Medicine , vol.7 , Issue.5 , pp. 355-364
    • Louboutin, J.-P.1    Rouger, K.2    Tinsley, J.M.3    Halldorson, J.4    Wilson, J.M.5
  • 24
    • 33846863589 scopus 로고    scopus 로고
    • Nitric oxide and peroxynitrite in health and disease
    • DOI 10.1152/physrev.00029.2006
    • Pacher, P., Beckman, J. S., and Liaudet, L. (2007) Nitric oxide and peroxynitrite in health and disease. Physiol. Rev. 87, 315-424 (Pubitemid 46217686)
    • (2007) Physiological Reviews , vol.87 , Issue.1 , pp. 315-424
    • Pacher, P.1    Beckman, J.S.2    Liaudet, L.3
  • 26
    • 33745168598 scopus 로고    scopus 로고
    • Muscle damage in mdx (dystrophic) mice: Role of calcium and reactive oxygen species
    • DOI 10.1111/j.1440-1681.2006.04394.x
    • Whitehead, N. P., Yeung, E. W., and Allen, D. G. (2006) Muscle damage in mdx (dystrophic) mice. Role of calcium and reactive oxygen species. Clin. Exp. Pharmacol. Physiol. 33, 657-662 (Pubitemid 43894030)
    • (2006) Clinical and Experimental Pharmacology and Physiology , vol.33 , Issue.7 , pp. 657-662
    • Whitehead, N.P.1    Yeung, E.W.2    Allen, D.G.3
  • 29
    • 0023739851 scopus 로고
    • Increased protein degradation results from elevated free calcium levels found in muscle from mdx mice
    • Turner, P. R., Westwood, T., Regen, C. M., and Steinhardt, R. A. (1988) Increased protein degradation results from elevated free calcium levels found in muscle from mdx mice. Nature 335, 735-738
    • (1988) Nature , vol.335 , pp. 735-738
    • Turner, P.R.1    Westwood, T.2    Regen, C.M.3    Steinhardt, R.A.4
  • 31
    • 0027234619 scopus 로고
    • Critical evaluation of cytosolic calcium determination in resting muscle fibres from normal and dystrophic (mdx) mice
    • DOI 10.1016/0143-4160(93)90006-R
    • Gailly, P., Boland, B., Himpens, B., Casteels, R., and Gillis, J. M. (1993) Critical evaluation of cytosolic calcium determination in resting muscle fibers from normal and dystrophic (mdx) mice. Cell Calcium 14, 473-483 (Pubitemid 23212089)
    • (1993) Cell Calcium , vol.14 , Issue.6 , pp. 473-483
    • Gailly, P.1    Boland, B.2    Himpens, B.3    Casteels, R.4    Gillis, J.M.5
  • 32
    • 0028414945 scopus 로고
    • 2+ concentrations are not elevated in resting cultured muscle from Duchenne (DMD) patients and in MDX mouse muscle fibers
    • 2+ concentrations are not elevated in resting cultured muscle from Duchenne (DMD) patients and in MDX mouse muscle fibers. Pflugers Arch. 426, 499-505
    • (1994) Pflugers Arch. , vol.426 , pp. 499-505
    • Pressmar, J.1    Brinkmeier, H.2    Seewald, M.J.3    Naumann, T.4    Rüdel, R.5
  • 33
    • 0031846599 scopus 로고    scopus 로고
    • Duchenne dystrophy. Electron microscopic findings point to a basic or early abnormality in the plasma membrane of the muscle fiber
    • Mokri, B., and Engel, A. G. (1998) Duchenne dystrophy. Electron microscopic findings point to a basic or early abnormality in the plasma membrane of the muscle fiber. Neurology 51, 1-10
    • (1998) Neurology , vol.51 , pp. 1-10
    • Mokri, B.1    Engel, A.G.2
  • 34
    • 0037119993 scopus 로고    scopus 로고
    • Involvement of TRPC in the abnormal calcium influx observed in dystrophic (mdx) mouse skeletal muscle fibers
    • Vandebrouck, C., Martin, D., Colson-Van Schoor, M., Debaix, H., and Gailly, P. (2002) Involvement of TRPC in the abnormal calcium influx observed in dystrophic (mdx) mouse skeletal muscle fibers. J. Cell Biol. 158, 1089-1096
    • (2002) J. Cell Biol. , vol.158 , pp. 1089-1096
    • Vandebrouck, C.1    Martin, D.2    Colson-Van Schoor, M.3    Debaix, H.4    Gailly, P.5
  • 35
    • 30744439614 scopus 로고    scopus 로고
    • Regulation of store-operated calcium entries and mitochondrial uptake by minidystrophin expression in cultured myotubes
    • DOI 10.1096/fj.04-3633fje
    • Vandebrouck, A., Ducret, T., Basset, O., Sebille, S., Raymond, G., Ruegg, U., Gailly, P., Cognard, C., and Constantin, B. (2006) Regulation of store-operated calcium entries and mitochondrial uptake by minidystrophin expression in cultured myotubes. FASEB J. 20, 136-138 (Pubitemid 43100492)
    • (2006) FASEB Journal , vol.20 , Issue.1 , pp. 136-138
    • Vandebrouck, A.1    Ducret, T.2    Basset, O.3    Sebille, S.4    Raymond, G.5    Ruegg, U.6    Gailly, P.7    Cognard, C.8    Constantin, B.9
  • 36
    • 48049121310 scopus 로고    scopus 로고
    • TRPC1 binds to caveolin-3 and is regulated by Src kinase. Role in Duchenne muscular dystrophy
    • Gervásio, O. L., Whitehead, N. P., Yeung, E. W., Phillips, W. D., and Allen, D. G. (2008) TRPC1 binds to caveolin-3 and is regulated by Src kinase. Role in Duchenne muscular dystrophy. J. Cell Sci. 121, 2246-2255
    • (2008) J. Cell Sci. , vol.121 , pp. 2246-2255
    • Gervásio, O.L.1    Whitehead, N.P.2    Yeung, E.W.3    Phillips, W.D.4    Allen, D.G.5
  • 41
    • 0037383635 scopus 로고    scopus 로고
    • From calcium to NF-κB signaling pathways in neurons
    • Lilienbaum, A., and Israël, A. (2003) From calcium to NF-κB signaling pathways in neurons. Mol. Cell. Biol. 23, 2680-2698
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 2680-2698
    • Lilienbaum, A.1    Israël, A.2
  • 42
    • 4444253776 scopus 로고    scopus 로고
    • Calcium-dependent regulation of the cell cycle via a novel MAPK-NF-κB pathway in Swiss 3T3 cells
    • DOI 10.1083/jcb.200402136
    • Sée, V., Rajala, N. K., Spiller, D. G., and White, M. R. (2004) Calcium-dependent regulation of the cell cycle via a novel MAPK-NF-κB pathway in Swiss 3T3 cells. J. Cell Biol. 166, 661-672 (Pubitemid 39181004)
    • (2004) Journal of Cell Biology , vol.166 , Issue.5 , pp. 661-672
    • See, V.1    Rajala, N.K.M.2    Spiller, D.G.3    White, M.R.H.4
  • 43
    • 0028932618 scopus 로고
    • Calpains are activated in necrotic fibers from mdx dystrophic mice
    • Spencer, M. J., Croall, D. E., and Tidball, J. G. (1995) Calpains are activated in necrotic fibers from mdx dystrophic mice. J. Biol. Chem. 270, 10909-10914
    • (1995) J. Biol. Chem. , vol.270 , pp. 10909-10914
    • Spencer, M.J.1    Croall, D.E.2    Tidball, J.G.3
  • 45
    • 0028264320 scopus 로고
    • Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy
    • DOI 10.1083/jcb.125.6.1275
    • Rando, T. A., and Blau, H. M. (1994) Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy. J. Cell Biol. 125, 1275-1287 (Pubitemid 24189532)
    • (1994) Journal of Cell Biology , vol.125 , Issue.6 , pp. 1275-1287
    • Rando, T.A.1    Blau, H.M.2
  • 46
    • 84555188331 scopus 로고    scopus 로고
    • Measurement of calcium release due to inositol trisphosphate receptors in skeletal muscle
    • Casas, M., Altamirano, F., and Jaimovich, E. (2012) Measurement of calcium release due to inositol trisphosphate receptors in skeletal muscle. Methods Mol. Biol. 798, 383-393
    • (2012) Methods Mol. Biol. , vol.798 , pp. 383-393
    • Casas, M.1    Altamirano, F.2    Jaimovich, E.3
  • 48
    • 77953356594 scopus 로고    scopus 로고
    • Adult muscle "stem" cells can be sustained in culture as free-floating myospheres
    • Westerman, K. A., Penvose, A., Yang, Z., Allen, P. D., and Vacanti, C. A. (2010) Adult muscle "stem" cells can be sustained in culture as free-floating myospheres. Exp. Cell Res. 316, 1966-1976
    • (2010) Exp. Cell Res. , vol.316 , pp. 1966-1976
    • Westerman, K.A.1    Penvose, A.2    Yang, Z.3    Allen, P.D.4    Vacanti, C.A.5
  • 49
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak, K. J., and Schmittgen, T. D. (2001) Analysis of relative gene expression data using real time quantitative PCR and the 2(-ΔΔCT) method. Methods 25, 402-408 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 50
    • 7244257594 scopus 로고    scopus 로고
    • PerlPrimer. Cross-platform, graphical primer design for standard, bisulfite, and real time PCR
    • Marshall, O. J. (2004) PerlPrimer. Cross-platform, graphical primer design for standard, bisulfite, and real time PCR. Bioinformatics 20, 2471-2472
    • (2004) Bioinformatics , vol.20 , pp. 2471-2472
    • Marshall, O.J.1
  • 51
    • 0028100737 scopus 로고
    • Novel modulators of skeletal muscle FKBP12/calcium channel complex from Ianthella basta. Role of FKBP12 in channel gating
    • Mack, M. M., Molinski, T. F., Buck, E. D., and Pessah, I. N. (1994) Novel modulators of skeletal muscle FKBP12/calcium channel complex from Ianthella basta. Role of FKBP12 in channel gating. J. Biol. Chem. 269, 23236-23249
    • (1994) J. Biol. Chem. , vol.269 , pp. 23236-23249
    • Mack, M.M.1    Molinski, T.F.2    Buck, E.D.3    Pessah, I.N.4
  • 52
    • 0031744741 scopus 로고    scopus 로고
    • Differences in both inositol 1,4,5-triphosphate mass and inositol 1,4,5- triphosphate receptors between normal and dystrophic between normal and dystrophic skeletal muscle cell lines
    • DOI 10.1002/(SICI)1097-4598(199807)21:7<902::AID-MUS8>3.0.CO;2-A
    • Liberona, J. L., Powell, J. A., Shenoi, S., Petherbridge, L., Caviedes, R., and Jaimovich, E. (1998) Differences in both inositol 1,4,5-trisphosphate mass and inositol 1,4,5-trisphosphate receptors between normal and dystrophic skeletal muscle cell lines. Muscle Nerve 21, 902-909 (Pubitemid 28262287)
    • (1998) Muscle and Nerve , vol.21 , Issue.7 , pp. 902-909
    • Liberona, J.L.1    Powell, J.A.2    Shenoi, S.3    Petherbridge, L.4    Caviedes, R.5    Jaimovich, E.6
  • 53
    • 77957835651 scopus 로고    scopus 로고
    • IP3-dependent post-tetanic calcium transients induced by electrostimulation of adult skeletal muscle fibers
    • Casas, M., Figueroa, R., Jorquera, G., Escobar, M., Molgó, J., and Jaimovich, E. (2010) IP3-dependent post-tetanic calcium transients induced by electrostimulation of adult skeletal muscle fibers. J. Gen. Physiol. 136, 455-467
    • (2010) J. Gen. Physiol. , vol.136 , pp. 455-467
    • Casas, M.1    Figueroa, R.2    Jorquera, G.3    Escobar, M.4    Molgó, J.5    Jaimovich, E.6
  • 56
    • 61349085391 scopus 로고    scopus 로고
    • STIM and Orai. The long-awaited constituents of store-operated calcium entry
    • Várnai, P., Hunyady, L., and Balla, T. (2009) STIM and Orai. The long-awaited constituents of store-operated calcium entry. Trends Pharmacol. Sci. 30, 118-128
    • (2009) Trends Pharmacol. Sci. , vol.30 , pp. 118-128
    • Várnai, P.1    Hunyady, L.2    Balla, T.3
  • 58
    • 0036092560 scopus 로고    scopus 로고
    • Drastic reduction of calsequestrin-like proteins and impaired calcium binding in dystrophic mdx muscle
    • Culligan, K., Banville, N., Dowling, P., and Ohlendieck, K. (2002) Drastic reduction of calsequestrin-like proteins and impaired calcium binding in dystrophic mdx muscle. J. Appl. Physiol. 92, 435-445 (Pubitemid 34671005)
    • (2002) Journal of Applied Physiology , vol.92 , Issue.2 , pp. 435-445
    • Culligan, K.1    Banville, N.2    Dowling, P.3    Ohlendieck, K.4
  • 59
    • 0030003967 scopus 로고    scopus 로고
    • The sarcoplasmic reticulum calcium pump is functionally altered in dystrophic muscle
    • DOI 10.1016/0304-4165(95)00180-8
    • Kargacin, M. E., and Kargacin, G. J. (1996) The sarcoplasmic reticulum calcium pump is functionally altered in dystrophic muscle. Biochim. Biophys. Acta 1290, 4-8 (Pubitemid 26173321)
    • (1996) Biochimica et Biophysica Acta - General Subjects , vol.1290 , Issue.1 , pp. 4-8
    • Kargacin, M.E.1    Kargacin, G.J.2
  • 60
    • 84858126592 scopus 로고    scopus 로고
    • 2+permeation explored from the lumen side in mdx muscle fibers under voltage control
    • 2+permeation explored from the lumen side in mdx muscle fibers under voltage control. J. Gen. Physiol. 139, 209-218
    • (2012) J. Gen. Physiol. , vol.139 , pp. 209-218
    • Robin, G.1    Berthier, C.2    Allard, B.3
  • 61
    • 78650140184 scopus 로고    scopus 로고
    • Overexpression of SERCA1a in the mdx diaphragm reduces susceptibility to contraction-induced damage
    • Morine, K. J., Sleeper, M. M., Barton, E. R., and Sweeney, H. L. (2010) Overexpression of SERCA1a in the mdx diaphragm reduces susceptibility to contraction-induced damage. Hum. Gene Ther. 21, 1735-1739
    • (2010) Hum. Gene Ther. , vol.21 , pp. 1735-1739
    • Morine, K.J.1    Sleeper, M.M.2    Barton, E.R.3    Sweeney, H.L.4
  • 63
    • 27744563126 scopus 로고    scopus 로고
    • Chronic treatment with agents that stabilize cytosolic IκB-α enhances survival and improves resting membrane potential in MDX muscle fibers subjected to chronic passive stretch
    • DOI 10.1016/j.nbd.2005.05.003, PII S0969996105001415
    • Carlson, C. G., Samadi, A., and Siegel, A. (2005) Chronic treatment with agents that stabilize cytosolic IκB-α enhances survival and improves resting membrane potential in MDX muscle fibers subjected to chronic passive stretch. Neurobiol. Dis. 20, 719-730 (Pubitemid 41619348)
    • (2005) Neurobiology of Disease , vol.20 , Issue.3 , pp. 719-730
    • Carlson, C.G.1    Samadi, A.2    Siegel, A.3
  • 65
    • 0034956422 scopus 로고    scopus 로고
    • Adult dystrophic (mdx) endplates exhibit reduced quantal size and enhanced quantal variation
    • DOI 10.1007/s004240100561
    • Carlson, C. G., and Roshek, D. M. (2001) Adult dystrophic (mdx) end plates exhibit reduced quantal size and enhanced quantal variation. Pflugers Arch. 442, 369-375 (Pubitemid 32591978)
    • (2001) Pflugers Archiv European Journal of Physiology , vol.442 , Issue.3 , pp. 369-375
    • Carlson, C.G.1    Roshek, D.M.2
  • 66
    • 2942696374 scopus 로고    scopus 로고
    • The action potential-evoked sarcoplasmic reticulum calcium release is impaired in mdx mouse muscle fibres
    • DOI 10.1113/jphysiol.2004.061291
    • Woods, C. E., Novo, D., DiFranco, M., and Vergara, J. L. (2004) The action potential evoked sarcoplasmic reticulum calcium release is impaired in mdx mouse muscle fibers. J. Physiol. 557, 59-75 (Pubitemid 38771637)
    • (2004) Journal of Physiology , vol.557 , Issue.1 , pp. 59-75
    • Woods, C.E.1    Novo, D.2    DiFranco, M.3    Vergara, J.L.4
  • 67
    • 55349131743 scopus 로고    scopus 로고
    • Comparison of the myoplasmic calcium transient elicited by an action potential in intact fibers of mdx and normal mice
    • Hollingworth, S., Zeiger, U., and Baylor, S. M. (2008) Comparison of the myoplasmic calcium transient elicited by an action potential in intact fibers of mdx and normal mice. J. Physiol. 586, 5063-5075
    • (2008) J. Physiol. , vol.586 , pp. 5063-5075
    • Hollingworth, S.1    Zeiger, U.2    Baylor, S.M.3
  • 68
    • 77951446319 scopus 로고    scopus 로고
    • Excitation-contraction coupling alterations in mdx and utrophin/dystrophin double knockout mice. A comparative study
    • Capote, J., DiFranco, M., and Vergara, J. L. (2010) Excitation- contraction coupling alterations in mdx and utrophin/dystrophin double knockout mice. A comparative study. Am. J. Physiol. Cell Physiol. 298, C1077-C1086
    • (2010) Am. J. Physiol. Cell Physiol. , vol.298
    • Capote, J.1    DiFranco, M.2    Vergara, J.L.3
  • 69
    • 44049092767 scopus 로고    scopus 로고
    • Signaling mechanisms in skeletal muscle. Acute responses and chronic adaptations to exercise
    • Röckl, K. S., Witczak, C. A., and Goodyear, L. J. (2008) Signaling mechanisms in skeletal muscle. Acute responses and chronic adaptations to exercise. IUBMB Life 60, 145-153
    • (2008) IUBMB Life , vol.60 , pp. 145-153
    • Röckl, K.S.1    Witczak, C.A.2    Goodyear, L.J.3
  • 70
    • 0033527443 scopus 로고    scopus 로고
    • Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase
    • DOI 10.1006/bbrc.1999.1454
    • Kumar, S., Jiang, M. S., Adams, J. L., and Lee, J. C. (1999) Pyridinylimidazole compound SB-203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase. Biochem. Biophys. Res. Commun. 263, 825-831 (Pubitemid 29490712)
    • (1999) Biochemical and Biophysical Research Communications , vol.263 , Issue.3 , pp. 825-831
    • Kumar, S.1    Jiang, M.S.2    Adams, J.L.3    Lee, J.C.4
  • 71
    • 0031803059 scopus 로고    scopus 로고
    • SB 203580 inhibits p38 mitogen-activated protein kinase, nitric oxide production, and inducible nitric oxide synthase in bovine cartilage-derived chondrocytes
    • Badger, A. M., Cook, M. N., Lark, M. W., Newman-Tarr, T. M., Swift, B. A., Nelson, A. H., Barone, F. C., and Kumar, S. (1998) SB-203580 inhibits p38 mitogen-activated protein kinase, nitric oxide production, and inducible nitric oxide synthase in bovine cartilage-derived chondrocytes. J. Immunol. 161, 467-473 (Pubitemid 28285556)
    • (1998) Journal of Immunology , vol.161 , Issue.1 , pp. 467-473
    • Badger, A.M.1    Cook, M.N.2    Lark, M.W.3    Newman-Tarr, T.M.4    Swift, B.A.5    Nelson, A.H.6    Barone, F.C.7    Kumar, S.8
  • 72
    • 0035906256 scopus 로고    scopus 로고
    • Forskolin inhibits expression of inducible nitric-oxide synthase mRNA via inhibiting the mitogen-activated protein kinase in C6 cells
    • Won, J. S., Lee, J. K., and Suh, H. W. (2001) Forskolin inhibits expression of inducible nitric-oxide synthase mRNA via inhibiting the mitogen-activated protein kinase in C6 cells. Brain Res. Mol. Brain Res. 89, 1-10
    • (2001) Brain Res. Mol. Brain Res. , vol.89 , pp. 1-10
    • Won, J.S.1    Lee, J.K.2    Suh, H.W.3
  • 73
    • 0035074761 scopus 로고    scopus 로고
    • Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice
    • DOI 10.1016/S0960-8966(00)00201-7, PII S0960896600002017
    • Nakamura, A., Harrod, G. V., and Davies, K. E. (2001) Activation of calcineurin and stress-activated protein kinase/p38-mitogen-activated protein kinase in hearts of utrophin-dystrophin knockout mice. Neuromuscul. Disord. 11, 251-259 (Pubitemid 32288795)
    • (2001) Neuromuscular Disorders , vol.11 , Issue.3 , pp. 251-259
    • Nakamura, A.1    Harrod, G.V.2    Davies, K.E.3
  • 74
    • 83455250428 scopus 로고    scopus 로고
    • Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle
    • Ljubicic, V., Khogali, S., Renaud, J. M., and Jasmin, B. J. (2012) Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle. Am. J. Physiol. Cell Physiol. 302, C110-C121
    • (2012) Am. J. Physiol. Cell Physiol. , vol.302
    • Ljubicic, V.1    Khogali, S.2    Renaud, J.M.3    Jasmin, B.J.4
  • 75
    • 0030741894 scopus 로고    scopus 로고
    • Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells
    • DOI 10.1074/jbc.272.30.18518
    • Kawasaki, H., Morooka, T., Shimohama, S., Kimura, J., Hirano, T., Gotoh, Y., and Nishida, E. (1997) Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells. J. Biol. Chem. 272, 18518-18521 (Pubitemid 27318185)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.30 , pp. 18518-18521
    • Kawasaki, H.1    Morooka, T.2    Shimohama, S.3    Kimura, J.4    Hirano, T.5    Gotoh, Y.6    Nishida, E.7
  • 77
    • 34547092191 scopus 로고    scopus 로고
    • Calcium induces increases in peroxisome proliferator-activated receptor γ coactivator-1α and alphamitochondrial biogenesis by a pathway leading to p38 mitogen-activated protein kinase activation
    • DOI 10.1074/jbc.M611252200
    • Wright, D. C., Geiger, P. C., Han, D. H., Jones, T. E., and Holloszy, J. O. (2007) Calcium induces increases in peroxisome proliferator-activated receptor γ coactivator-1α and mitochondrial biogenesis by a pathway leading to p38 mitogen-activated protein kinase activation. J. Biol. Chem. 282, 18793-18799 (Pubitemid 47100154)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.26 , pp. 18793-18799
    • Wright, D.C.1    Geiger, P.C.2    Han, D.-H.3    Jones, T.E.4    Holloszy, J.O.5
  • 80
    • 45449104412 scopus 로고    scopus 로고
    • Transient receptor potential cation channels in normal and dystrophic mdx muscle
    • Krüger, J., Kunert-Keil, C., Bisping, F., and Brinkmeier, H. (2008) Transient receptor potential cation channels in normal and dystrophic mdx muscle. Neuromuscul. Disord. 18, 501-513
    • (2008) Neuromuscul. Disord. , vol.18 , pp. 501-513
    • Krüger, J.1    Kunert-Keil, C.2    Bisping, F.3    Brinkmeier, H.4
  • 81
    • 0345547431 scopus 로고    scopus 로고
    • Regulation of the expression of inducible nitric oxide synthase
    • DOI 10.1515/BC.2003.152
    • Kleinert, H., Schwarz, P. M., and Förstermann, U. (2003) Regulation of the expression of inducible nitric-oxide synthase. Biol. Chem. 384, 1343-1364 (Pubitemid 37508640)
    • (2003) Biological Chemistry , vol.384 , Issue.10-11 , pp. 1343-1364
    • Kleinert, H.1    Schwarz, P.M.2    Forstermann, U.3


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