Sustained action of ceramide on the insulin signaling pathway in muscle cells: Implication of the double-stranded RNA-activated protein kinase

Journal of Biological Chemistry

Volumn 291, Issue 6, 2016, Pages 3019-3029

  Hassan, Rima Hage ^a,b,c   De Sousa, Ana Catarina Pacheco ^a,b,c   Mahfouz, Rana ^a,b,c   Hainault, Isabelle ^a,b,c   Blachnio Zabielska, Agnieszka ^d   Bourron, Olivier ^a,b,c,e   Koskas, Fabien ^a,e   Górski, Jan ^d   Ferré, Pascal ^a,b,c   Foufelle, Fabienne ^a,b,c   Hajduch, Eric ^a,b,c  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; CERAMIDES; ENZYMES; FATTY ACIDS; INSULIN; MUSCLE; NUCLEIC ACIDS; PALMITIC ACID; PHOSPHORYLATION; PROTEINS; RNA; SATURATED FATTY ACIDS; SIGNALING;

ACTIVATED PROTEINS; DOUBLE-STRANDED RNA; EXPERIMENTAL PROCEDURE; INSULIN RESISTANCE; LONG-TERM EFFECTS; PHARMACOLOGICAL INHIBITORS; RNA-DEPENDENT PROTEIN KINASE; SERINE PHOSPHORYLATION;

CELL SIGNALING;

CERAMIDE; INSULIN RECEPTOR SUBSTRATE 1; MESSENGER RNA; PALMITIC ACID; PROTEIN KINASE B; PROTEIN KINASE R; SATURATED FATTY ACID; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; INSULIN; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, HUMAN; IRS1 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PROTEIN KINASE R, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; C2C12 CELL; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VIVO STUDY; INHIBITION KINETICS; INSULIN RESISTANCE; INSULIN SIGNALING PATHWAY; MALE; MOUSE; MUSCLE CELL; MYOTUBE; NONHUMAN; PKR GENE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CELL LINE; CYTOLOGY; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SKELETAL MUSCLE;

ANIMALS; CELL LINE; CERAMIDES; EIF-2 KINASE; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MALE; MAP KINASE KINASE 4; MICE; MUSCLE, SKELETAL; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84958020016     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.686949     Document Type: Article

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