-
1
-
-
14644427890
-
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
-
DOI 10.1038/nm1166
-
Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, Lee J, Shoelson SE 2005 Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB. Nat Med 11:183-190 (Pubitemid 40321354)
-
(2005)
Nature Medicine
, vol.11
, Issue.2
, pp. 183-190
-
-
Cai, D.1
Yuan, M.2
Frantz, D.F.3
Melendez, P.A.4
Hansen, L.5
Lee, J.6
Shoelson, S.E.7
-
2
-
-
0034708832
-
307
-
DOI 10.1074/jbc.275.12.9047
-
Aguirre V, Uchida T, Yenush L, Davis R, White MF 2000 The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307). J Biol Chem 275:9047-9054 (Pubitemid 30180265)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.12
, pp. 9047-9054
-
-
Aguirre, V.1
Uchida, T.2
Yenush, L.3
Davis, R.4
White, M.F.5
-
3
-
-
0035979775
-
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkß
-
DOI 10.1126/science.1061620
-
Yuan M, Konstantopoulos N, Lee J, Hansen L, Li ZW, Karin M, Shoelson SE 2001 Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkß. Science 293:1673-1677 (Pubitemid 32807849)
-
(2001)
Science
, vol.293
, Issue.5535
, pp. 1673-1677
-
-
Yuan, M.1
Konstantopoulos, N.2
Lee, J.3
Hansen, L.4
Li, Z.-W.5
Karin, M.6
Shoelson, S.E.7
-
4
-
-
0034770292
-
Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle
-
DOI 10.1038/nm1001-1138
-
Perreault M, MaretteA 2001 Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle. Nat Med 7:1138-1143 (Pubitemid 33010023)
-
(2001)
Nature Medicine
, vol.7
, Issue.10
, pp. 1138-1143
-
-
Perreault, M.1
Marette, A.2
-
5
-
-
0037153158
-
A central, role for JNK in obesity and insulin resistance
-
DOI 10.1038/nature01137
-
Hirosumi J, Tuncman G, Chang L, Görgün CZ, Uysal KT, Maeda K, Karin M, Hotamisligil GS 2002 A central role for JNK in obesity and insulin resistance. Nature 420:333-336 (Pubitemid 35398190)
-
(2002)
Nature
, vol.420
, Issue.6913
, pp. 333-336
-
-
Hirosumi, J.1
Tuncman, G.2
Chang, L.3
Gorgun, C.Z.4
Uysal, K.T.5
Maeda, K.6
Karin, M.7
Hotamisligil, G.S.8
-
6
-
-
0037474274
-
c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade
-
DOI 10.1074/jbc.M208359200
-
Lee YH, Giraud J, Davis RJ, White MF 2003 c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade. J Biol Chem 278:2896-2902 (Pubitemid 36801194)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.5
, pp. 2896-2902
-
-
Lee, Y.H.1
Giraud, J.2
Davis, R.J.3
White, M.F.4
-
7
-
-
20044387026
-
IKK-β links inflammation to obesity-induced insulin resistance
-
DOI 10.1038/nm1185
-
Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J, Karin M 2005 IKK-β links inflammation to obesity-induced insulin resistance. Nat Med 11:191-198 (Pubitemid 40321355)
-
(2005)
Nature Medicine
, vol.11
, Issue.2
, pp. 191-198
-
-
Arkan, M.C.1
Hevener, A.L.2
Greten, F.R.3
Maeda, S.4
Li, Z.-W.5
Long, J.M.6
Wynshaw-Boris, A.7
Poli, G.8
Olefsky, J.9
Karin, M.10
-
8
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
DOI 10.1172/JCI200319246
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante Jr AW 2003 Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112:1796-1808 (Pubitemid 38063703)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
9
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
DOI 10.1172/JCI200319451
-
Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H 2003 Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112:1821-1830 (Pubitemid 38063705)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
10
-
-
33748750917
-
Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance
-
DOI 10.1074/jbc.M601284200
-
Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T 2006 Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance. J Biol Chem 281:26602-26614 (Pubitemid 44401869)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.36
, pp. 26602-26614
-
-
Kamei, N.1
Tobe, K.2
Suzuki, R.3
Ohsugi, M.4
Watanabe, T.5
Kubota, N.6
Ohtsuka-Kowatari, N.7
Kumagai, K.8
Sakamoto, K.9
Kobayashi, M.10
Yamauchi, T.11
Ueki, K.12
Oishi, Y.13
Nishimura, S.14
Manabe, I.15
Hashimoto, H.16
Ohnishi, Y.17
Ogata, H.18
Tokuyama, K.19
Tsunoda, M.20
Ide, T.21
Murakami, K.22
Nagai, R.23
Kadowaki, T.24
more..
-
12
-
-
34547602916
-
Loss-of-function mutation in toll-like receptor 4 prevents diet-induced obesity and insulin resistance
-
DOI 10.2337/db06-1595
-
Tsukumo DM, Carvalho-Filho MA, Carvalheira JB, Prada PO, Hirabara SM, Schenka AA, Araújo EP, Vassallo J, Curi R, Velloso LA, Saad MJ 2007 Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance. Diabetes 56:1986-1998 (Pubitemid 47195825)
-
(2007)
Diabetes
, vol.56
, Issue.8
, pp. 1986-1998
-
-
Tsukumo, D.M.L.1
Carvalho-Filho, M.A.2
Carvalheira, J.B.C.3
Prada, P.O.4
Hirabara, S.M.5
Schenka, A.A.6
Araujo, E.P.7
Vassallo, J.8
Curi, R.9
Velloso, L.A.10
Saad, M.J.A.11
-
13
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
DOI 10.1172/JCI28898
-
Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS 2006 TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 116:3015-3025 (Pubitemid 44684486)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.11
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
Tzameli, I.4
Yin, H.5
Flier, J.S.6
-
14
-
-
0034082457
-
PKR stimulates NF-κB irrespective of its kinase function by interacting with the IκB kinase complex
-
DOI 10.1128/MCB.20.13.4532-4542.2000
-
Bonnet MC, Weil R,Dam E, Hovanessian AG, Meurs EF 2000 PKR stimulates NF-κB irrespective of its kinase function by interacting with the IκB kinase complex. Mol Cell Biol 20:4532-4542 (Pubitemid 30396101)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.13
, pp. 4532-4542
-
-
Bonnet, M.C.1
Weil, R.2
Dam, E.3
Hovanessian, A.G.4
Meurs, E.F.5
-
15
-
-
0034663942
-
The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin
-
Goh KC, deVeer MJ, Williams BR 2000 The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin. EMBO J 19:4292-4297 (Pubitemid 30623740)
-
(2000)
EMBO Journal
, vol.19
, Issue.16
, pp. 4292-4297
-
-
Goh, K.C.1
DeVeer, M.J.2
Williams, B.R.G.3
-
16
-
-
33847236171
-
Genetic deletion of PKR abrogates TNF-induced activation of IκBα kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation
-
Takada Y, Ichikawa H, Pataer A, Swisher S, Aggarwal BB 2007 Genetic deletion of PKR abrogates TNF-induced activation of IκBα kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation. Oncogene 26:1201-1212
-
(2007)
Oncogene
, vol.26
, pp. 1201-1212
-
-
Takada, Y.1
Ichikawa, H.2
Pataer, A.3
Swisher, S.4
Aggarwal, B.B.5
-
17
-
-
33750458339
-
Inhibitor of double stranded RNA-dependent protein kinase protects against cell damage induced by ER stress
-
DOI 10.1016/j.neulet.2006.09.074, PII S0304394006010159
-
Shimazawa M, Hara H 2006 Inhibitor of double stranded RNA-dependent protein kinase protects against cell damage induced by ER stress. Neurosci Lett 409:192-195 (Pubitemid 44648572)
-
(2006)
Neuroscience Letters
, vol.409
, Issue.3
, pp. 192-195
-
-
Shimazawa, M.1
Hara, H.2
-
18
-
-
75749108288
-
Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis
-
Nakamura T, Furuhashi M, Li P, Cao H, Tuncman G, Sonenberg N, Gorgun CZ, Hotamisligil GS 2010 Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis. Cell 140:338-348
-
(2010)
Cell
, vol.140
, pp. 338-348
-
-
Nakamura, T.1
Furuhashi, M.2
Li, P.3
Cao, H.4
Tuncman, G.5
Sonenberg, N.6
Gorgun, C.Z.7
Hotamisligil, G.S.8
-
19
-
-
0037064118
-
Functional characterization of pkr gene products expressed in cells from mice with a targeted deletion of the N terminus or C terminus domain of PKR
-
DOI 10.1074/jbc.M203564200
-
Baltzis D, Li S, Koromilas AE 2002 Functional characterization of pkr gene products expressed in cells from mice with a targeted deletion of the N terminus or C terminus domain of PKR. J Biol Chem 277:38364-38372 (Pubitemid 35154692)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.41
, pp. 38364-38372
-
-
Baltzis, D.1
Li, S.2
Koromilas, A.E.3
-
20
-
-
77958048585
-
The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cells
-
Yang X, Nath A, Opperman MJ, Chan C 2010 The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cells. Mol Biol Cell 21:3449-3458
-
(2010)
Mol Biol Cell
, vol.21
, pp. 3449-3458
-
-
Yang, X.1
Nath, A.2
Opperman, M.J.3
Chan, C.4
-
21
-
-
0029590069
-
Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase
-
Yang YL, Reis LF, Pavlovic J, Aguzzi A, Schäfer R, Kumar A, Williams BR, Aguet M, Weissmann C 1995 Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase. EMBO J 14:6095-6106 (Pubitemid 26007297)
-
(1995)
EMBO Journal
, vol.14
, Issue.24
, pp. 6095-6106
-
-
Yang, Y.-L.1
Reis, L.F.L.2
Paylovic, J.3
Aguzzi, S.4
Schafer, R.5
Kumar, A.6
Williams, B.R.G.7
Aguet, M.8
Weissmann, C.9
-
22
-
-
79952389476
-
Physical exercise reduces circulating lipopolysaccharide and TLR4 activation and improves insulin signaling in tissues of DIO rats
-
Oliveira AG, Carvalho BM, Tobar N, Ropelle ER, Pauli JR, Bagarolli RA, Guadagnini D, Carvalheira JB, Saad MJ 2011 Physical exercise reduces circulating lipopolysaccharide and TLR4 activation and improves insulin signaling in tissues of DIO rats. Diabetes 60:784-796
-
(2011)
Diabetes
, vol.60
, pp. 784-796
-
-
Oliveira, A.G.1
Carvalho, B.M.2
Tobar, N.3
Ropelle, E.R.4
Pauli, J.R.5
Bagarolli, R.A.6
Guadagnini, D.7
Carvalheira, J.B.8
Saad, M.J.9
-
23
-
-
0031421638
-
Quantitative measurement of islet glucagon response to hypoglycemia by confocal fluorescence imaging in diabetic rats: Effects of phlorizin treatment
-
Rastogi KS, Cooper RL, Shi ZQ, Vranic M 1997 Quantitative measurement of islet glucagon response to hypoglycemia by confocal fluorescence imaging in diabetic rats: effects of phlorizin treatment. Endocrine 7:367-375 (Pubitemid 28223945)
-
(1997)
Endocrine
, vol.7
, Issue.3
, pp. 367-375
-
-
Rastogi, K.S.1
Cooper, R.L.2
Shi, Z.Q.3
Vranic, M.4
-
24
-
-
77954980506
-
Glucagon deficiency reduces hepatic glucose production and improves glucose tolerance in adult mice
-
Hancock AS, Du A, Liu J, Miller M, May CL 2010 Glucagon deficiency reduces hepatic glucose production and improves glucose tolerance in adult mice. Mol Endocrinol 24:1605-1614
-
(2010)
Mol Endocrinol
, vol.24
, pp. 1605-1614
-
-
Hancock, A.S.1
Du, A.2
Liu, J.3
Miller, M.4
May, C.L.5
-
25
-
-
80054910148
-
Diacerhein improves glucose tolerance and insulin sensitivity in mice on a high-fat diet
-
Tobar N, Oliveira AG, Guadagnini D, Bagarolli RA, Rocha GZ, Araújo TG, Santos-Silva JC, Zollner RL, Boechat LH, Carvalheira JB, Prada PO, Saad MJ 2011 Diacerhein improves glucose tolerance and insulin sensitivity in mice on a high-fat diet. Endocrinology 152:4080-4093
-
(2011)
Endocrinology
, vol.152
, pp. 4080-4093
-
-
Tobar, N.1
Oliveira, A.G.2
Guadagnini, D.3
Bagarolli, R.A.4
Rocha, G.Z.5
Araújo, T.G.6
Santos-Silva, J.C.7
Zollner, R.L.8
Boechat, L.H.9
Carvalheira, J.B.10
Prada, P.O.11
Saad, M.J.12
-
26
-
-
47949090359
-
Reduction of hypothalamic protein tyrosine phosphatase improves insulin and leptin resistance in diet-induced obese rats
-
Picardi PK, Calegari VC, Prada Pde O, Moraes JC, Araújo E, Marcondes MC, Ueno M, Carvalheira JB, Velloso LA, Saad MJ 2008 Reduction of hypothalamic protein tyrosine phosphatase improves insulin and leptin resistance in diet-induced obese rats. Endocrinology 149:3870-3880
-
(2008)
Endocrinology
, vol.149
, pp. 3870-3880
-
-
Picardi, P.K.1
Calegari, V.C.2
Prada Pde, O.3
Moraes, J.C.4
Araújo, E.5
Marcondes, M.C.6
Ueno, M.7
Carvalheira, J.B.8
Velloso, L.A.9
Saad, M.J.10
-
27
-
-
0037464454
-
Palmitate acutely raises glycogen synthesis in rat soleus muscle by a mechanism that requires its metabolization (Randle cycle)
-
DOI 10.1016/S0014-5793(03)00316-8
-
Massao Hirabara S, de Oliveira Carvalho CR, Mendonça JR, Piltcher Haber E, Fernandes LC, Curi R 2003 Palmitate acutely raises glycogen synthesis in rat soleus muscle by a mechanism that requires its metabolization (Randle cycle). FEBS Lett 541:109-114 (Pubitemid 36428927)
-
(2003)
FEBS Letters
, vol.541
, Issue.1-3
, pp. 109-114
-
-
Massao, H.S.1
De Oliveira, C.C.R.2
Mendonca, J.R.3
Piltcher, H.E.4
Fernandes, L.C.5
Curi, R.6
-
28
-
-
0346458780
-
Regulation of Cbl-Associated Protein/Cbl Pathway in Muscle and Adipose Tissues of Two Animal Models of Insulin Resistance
-
DOI 10.1210/en.2003-0575
-
Thirone AC, Carvalheira JB, Hirata AE, Velloso LA, Saad MJ 2004 Regulation of Cbl-associated protein/Cbl pathway in muscle and adipose tissues of two animal models of insulin resistance. Endocrinology 145:281-293 (Pubitemid 38094522)
-
(2004)
Endocrinology
, vol.145
, Issue.1
, pp. 281-293
-
-
Thirone, A.C.P.1
Carvalheira, J.B.C.2
Hirata, A.E.3
Velloso, L.A.4
Saad, M.J.A.5
-
29
-
-
20044364733
-
Western diet modulates insulin signaling, c-Jun N-terminal kinase activity, and insulin receptor substrate-1ser307 phosphorylation in a tissue-specific fashion
-
Prada PO, Zecchin HG, Gasparetti AL, Torsoni MA, Ueno M, Hirata AE, Corezola do Amaral ME, Höer NF, Boschero AC, Saad MJ 2005 Western diet modulates insulin signaling, c-Jun N-terminal kinase activity, and insulin receptor substrate-1ser307 phosphorylation in a tissue-specific fashion. Endocrinology 146:1576-1587
-
(2005)
Endocrinology
, vol.146
, pp. 1576-1587
-
-
Prada, P.O.1
Zecchin, H.G.2
Gasparetti, A.L.3
Torsoni, M.A.4
Ueno, M.5
Hirata, A.E.6
Corezola Do Amaral, M.E.7
Höer, N.F.8
Boschero, A.C.9
Saad, M.J.10
-
30
-
-
30944448233
-
Acute effect of fatty acids on metabolism and mitochondrial coupling in skeletal muscle
-
DOI 10.1016/j.bbabio.2005.11.007, PII S0005272805002574
-
Hirabara SM, Silveira LR, Alberici LC, Leandro CV, Lambertucci RH, Polimeno GC, Cury Boaventura MF, Procopio J, Vercesi AE, Curi R 2006 Acute effect of fatty acids on metabolism and mitochondrial coupling in skeletal muscle. Biochim Biophys Acta 1757:57-66 (Pubitemid 43113322)
-
(2006)
Biochimica et Biophysica Acta - Bioenergetics
, vol.1757
, Issue.1
, pp. 57-66
-
-
Hirabara, S.M.1
Silveira, L.R.2
Alberici, L.C.3
Leandro, C.V.G.4
Lambertucci, R.H.5
Polimeno, G.C.6
Cury, B.M.F.7
Procopio, J.8
Vercesi, A.E.9
Curi, R.10
-
31
-
-
77949531986
-
A dynamic analysis of IRS-PKR signaling in liver cells: A discrete modeling approach
-
Wu M, Yang X, Chan C 2009 A dynamic analysis of IRS-PKR signaling in liver cells: a discrete modeling approach. PLoS One 4:e8040
-
(2009)
PLoS One
, vol.4
-
-
Wu, M.1
Yang, X.2
Chan, C.3
-
33
-
-
31044456529
-
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
-
DOI 10.1172/JCI24335
-
Weisberg SP, Hunter D, Huber R, Lemieux J, Slaymaker S, Vaddi K, Charo I, Leibel RL, Ferrante Jr AW 2006 CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J Clin Invest 116:115-124 (Pubitemid 43121796)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.1
, pp. 115-124
-
-
Weisberg, S.P.1
Hunter, D.2
Huber, R.3
Lemieux, J.4
Slaymaker, S.5
Vaddi, K.6
Charo, I.7
Leibel, R.L.8
Ferrante Jr., A.W.9
-
34
-
-
33745216724
-
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
-
Kanda H, Tateya S, Tamori Y, Kotani K, Hiasa K, Kitazawa R, Kitazawa S, Miyachi H, Maeda S, Egashira K, Kasuga M 2006 MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 116: 1494-1505
-
(2006)
J Clin Invest
, vol.116
, pp. 1494-1505
-
-
Kanda, H.1
Tateya, S.2
Tamori, Y.3
Kotani, K.4
Hiasa, K.5
Kitazawa, R.6
Kitazawa, S.7
Miyachi, H.8
Maeda, S.9
Egashira, K.10
Kasuga, M.11
-
35
-
-
67649869416
-
Macrophage-derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice
-
Qatanani M, Szwergold NR, Greaves DR, Ahima RS, Lazar MA 2009 Macrophage-derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice. J Clin Invest 119:531-539
-
(2009)
J Clin Invest
, vol.119
, pp. 531-539
-
-
Qatanani, M.1
Szwergold, N.R.2
Greaves, D.R.3
Ahima, R.S.4
Lazar, M.A.5
-
36
-
-
3042636409
-
Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1
-
DOI 10.1210/en.2003-1400
-
Goren HJ, Kulkarni RN, Kahn CR 2004 Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1. Endocrinology 145:3307-3323 (Pubitemid 38830003)
-
(2004)
Endocrinology
, vol.145
, Issue.7
, pp. 3307-3323
-
-
Goren, H.J.1
Kulkarni, R.N.2
Kahn, C.R.3
-
37
-
-
76149090834
-
Role of the hypothalamic-pituitary-thyroid axis in metabolic regulation by JNK1
-
Sabio G, Cavanagh-Kyros J, Barrett T, Jung DY, Ko HJ, Ong H, Morel C, Mora A, Reilly J, Kim JK, Davis RJ 2010 Role of the hypothalamic-pituitary- thyroid axis in metabolic regulation by JNK1. Genes Dev 24:256-264
-
(2010)
Genes Dev
, vol.24
, pp. 256-264
-
-
Sabio, G.1
Cavanagh-Kyros, J.2
Barrett, T.3
Jung, D.Y.4
Ko, H.J.5
Ong, H.6
Morel, C.7
Mora, A.8
Reilly, J.9
Kim, J.K.10
Davis, R.J.11
-
38
-
-
2542576429
-
Effects of insulin, contraction, and phorbol esters on mitogen-activated protein kinase signaling in skeletal muscle from lean and ob/ob mice
-
DOI 10.2337/diabetes.53.6.1436
-
Leng Y, Steiler TL, Zierath JR 2004 Effects of insulin, contraction, and phorbol esters on mitogen-activated protein kinase signaling in skeletal muscle from lean and ob/ob mice. Diabetes 53:1436-1444 (Pubitemid 38697654)
-
(2004)
Diabetes
, vol.53
, Issue.6
, pp. 1436-1444
-
-
Leng, Y.1
Steiler, T.L.2
Zierath, J.R.3
-
40
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
DOI 10.1126/science.1128294
-
Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO, Görgün CZ, Hotamisligil GS 2006 Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 313:1137-1140 (Pubitemid 44300242)
-
(2006)
Science
, vol.313
, Issue.5790
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Gorgun, C.Z.7
Hotamisligil, G.S.8
-
41
-
-
0038714270
-
Poly(dI-dC)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFκB and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR
-
DOI 10.1074/jbc.M300562200
-
Jiang Z, Zamanian-Daryoush M, Nie H, Silva AM, Williams BR, Li X 2003 Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFκB and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR. J Biol Chem 278:16713-16719 (Pubitemid 36799536)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.19
, pp. 16713-16719
-
-
Jiang, Z.1
Zamanian-Daryoush, M.2
Nie, H.3
Silva, A.M.4
Williams, B.R.G.5
Li, X.6
-
42
-
-
0035853831
-
Ceramide regulates protein synthesis by a novel mechanism involving the cellular PKR activator RAX
-
Ruvolo PP, Gao F, Blalock WL, Deng X, May WS 2001 Ceramide regulates protein synthesis by a novel mechanism involving the cellular PKR activator RAX. J Biol Chem 276:11754-11758
-
(2001)
J Biol Chem
, vol.276
, pp. 11754-11758
-
-
Ruvolo, P.P.1
Gao, F.2
Blalock, W.L.3
Deng, X.4
May, W.S.5
-
43
-
-
0035555301
-
TIRAP: An adapter molecule in the Toll signaling pathway
-
Horng T, Barton GM, Medzhitov R 2001 TIRAP: an adapter molecule in the Toll signaling pathway. Nat Immunol 2:835-841
-
(2001)
Nat Immunol
, vol.2
, pp. 835-841
-
-
Horng, T.1
Barton, G.M.2
Medzhitov, R.3
-
44
-
-
33845627785
-
Impact of protein kinase PKR in cell biology: From antiviral to antiproliferative action
-
DOI 10.1128/MMBR.00027-06
-
García MA, Gil J, Ventoso I, Guerra S, Domingo E, Rivas C, Esteban M 2006 Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action. Microbiol Mol Biol Rev 70:1032-1060 (Pubitemid 44958263)
-
(2006)
Microbiology and Molecular Biology Reviews
, vol.70
, Issue.4
, pp. 1032-1060
-
-
Garcia, M.A.1
Gil, J.2
Ventoso, I.3
Guerra, S.4
Domingo, E.5
Rivas, C.6
Esteban, M.7
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