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Volumn 31, Issue 2, 2016, Pages 108-116

Obesity, Asthma, and the Microbiome

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ASTHMA; COMPLICATION; GASTROINTESTINAL TRACT; HUMAN; LUNG; MICROBIOLOGY; MICROFLORA; OBESITY; PATHOPHYSIOLOGY; PHYSIOLOGY; RISK FACTOR;

EID: 84957890401     PISSN: 15489213     EISSN: 15489221     Source Type: Journal    
DOI: 10.1152/physiol.00045.2015     Document Type: Review
Times cited : (29)

References (154)
  • 1
    • 84908151057 scopus 로고    scopus 로고
    • Is eating behavior manipulated by the gastrointestinal microbiota? Evolutionary pressures and potential mechanisms
    • Alcock J, Maley CC, Aktipis CA. Is eating behavior manipulated by the gastrointestinal microbiota? Evolutionary pressures and potential mechanisms. Bioessays 36: 940-949, 2014.
    • (2014) Bioessays , vol.36 , pp. 940-949
    • Alcock, J.1    Maley, C.C.2    Aktipis, C.A.3
  • 2
    • 37549023822 scopus 로고    scopus 로고
    • Ozone exposure and lung function: Effect modified by obesity and airways hyperresponsiveness in the VA normative aging study
    • Alexeeff SE, Litonjua AA, Suh H, Sparrow D, Vokonas PS, Schwartz J. Ozone exposure and lung function: effect modified by obesity and airways hyperresponsiveness in the VA normative aging study. Chest 132: 1890-1897, 2007.
    • (2007) Chest , vol.132 , pp. 1890-1897
    • Alexeeff, S.E.1    Litonjua, A.A.2    Suh, H.3    Sparrow, D.4    Vokonas, P.S.5    Schwartz, J.6
  • 3
    • 79960843789 scopus 로고    scopus 로고
    • Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells
    • Arnold IC, Dehzad N, Reuter S, Martin H, Becher B, Taube C, Muller A. Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells. J Clin Invest 121: 3088-3093, 2011.
    • (2011) J Clin Invest , vol.121 , pp. 3088-3093
    • Arnold, I.C.1    Dehzad, N.2    Reuter, S.3    Martin, H.4    Becher, B.5    Taube, C.6    Muller, A.7
  • 4
    • 84872124577 scopus 로고    scopus 로고
    • Inhibition of leptin regulation of parasympathetic signaling as a cause of extreme body weight-associated asthma
    • Arteaga-Solis E, Zee T, Emala CW, Vinson C, Wess J, Karsenty G. Inhibition of leptin regulation of parasympathetic signaling as a cause of extreme body weight-associated asthma. Cell Metab 17: 35-48, 2013.
    • (2013) Cell Metab , vol.17 , pp. 35-48
    • Arteaga-Solis, E.1    Zee, T.2    Emala, C.W.3    Vinson, C.4    Wess, J.5    Karsenty, G.6
  • 9
    • 0141497509 scopus 로고    scopus 로고
    • How do corticosteroids work in asthma?
    • Barnes PJ, Adcock IM. How do corticosteroids work in asthma? Ann Int Med 139: 359-370, 2003.
    • (2003) Ann Int Med , vol.139 , pp. 359-370
    • Barnes, P.J.1    Adcock, I.M.2
  • 15
    • 84859090297 scopus 로고    scopus 로고
    • Effect of bariatric surgery on airway response and lung function in obese subjects with asthma
    • Boulet LP, Turcotte H, Martin J, Poirier P. Effect of bariatric surgery on airway response and lung function in obese subjects with asthma. Respir Med 106: 651-660, 2012.
    • (2012) Respir Med , vol.106 , pp. 651-660
    • Boulet, L.P.1    Turcotte, H.2    Martin, J.3    Poirier, P.4
  • 17
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani PD, Bibiloni R, Knauf C, Waget A, Neyrinck AM, Delzenne NM, Burcelin R. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 57: 1470-1481, 2008.
    • (2008) Diabetes , vol.57 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3    Waget, A.4    Neyrinck, A.M.5    Delzenne, N.M.6    Burcelin, R.7
  • 19
    • 84887132830 scopus 로고    scopus 로고
    • Bifidobacterium CECT 7765 improves metabolic and immunological alterations associated with obesity in high-fat diet-fed mice
    • Cano PG, Santacruz A, Trejo FM, Sanz Y. Bifidobacterium CECT 7765 improves metabolic and immunological alterations associated with obesity in high-fat diet-fed mice. Obesity (Silver Spring) 21: 2310-2321, 2013.
    • (2013) Obesity (Silver Spring) , vol.21 , pp. 2310-2321
    • Cano, P.G.1    Santacruz, A.2    Trejo, F.M.3    Sanz, Y.4
  • 23
    • 84862322604 scopus 로고    scopus 로고
    • Metabolomics characterization of energy metabolism reveals glycogen accumulation in gut-microbiota-lacking mice
    • Chuang HL, Huang YT, Chiu CC, Liao CD, Hsu FL, Huang CC, Hou CC. Metabolomics characterization of energy metabolism reveals glycogen accumulation in gut-microbiota-lacking mice. J Nutr Biochem 23: 752-758, 2012.
    • (2012) J Nutr Biochem , vol.23 , pp. 752-758
    • Chuang, H.L.1    Huang, Y.T.2    Chiu, C.C.3    Liao, C.D.4    Hsu, F.L.5    Huang, C.C.6    Hou, C.C.7
  • 25
    • 77952339975 scopus 로고    scopus 로고
    • Integration of metabolomics and transcriptomics data to aid biomarker discovery in Type 2 diabetes
    • Connor SC, Hansen MK, Corner A, Smith RF, Ryan TE. Integration of metabolomics and transcriptomics data to aid biomarker discovery in Type 2 diabetes. Mol Biosyst 6: 909-921, 2010.
    • (2010) Mol Biosyst , vol.6 , pp. 909-921
    • Connor, S.C.1    Hansen, M.K.2    Corner, A.3    Smith, R.F.4    Ryan, T.E.5
  • 27
    • 80054913827 scopus 로고    scopus 로고
    • Targeting gut microbiota in obesity: Effects of prebiotics and probiotics
    • Delzenne NM, Neyrinck AM, Backhed F, Cani PD. Targeting gut microbiota in obesity: effects of prebiotics and probiotics. Nat Rev Endocrinol 7: 639-646, 2011.
    • (2011) Nat Rev Endocrinol , vol.7 , pp. 639-646
    • Delzenne, N.M.1    Neyrinck, A.M.2    Backhed, F.3    Cani, P.D.4
  • 39
    • 84897138661 scopus 로고    scopus 로고
    • A taxonomic signature of obesity in the microbiome? Getting to the guts of the matter
    • Finucane MM, Sharpton TJ, Laurent TJ, Pollard KS. A taxonomic signature of obesity in the microbiome? Getting to the guts of the matter. PLos One 9: e84689, 2014.
    • (2014) Plos One , vol.9
    • Finucane, M.M.1    Sharpton, T.J.2    Laurent, T.J.3    Pollard, K.S.4
  • 41
    • 84901422463 scopus 로고    scopus 로고
    • The role of diet on intestinal microbiota metabolism: Downstream impacts on host immune function and health, and therapeutic implications
    • Goldsmith JR, Sartor RB. The role of diet on intestinal microbiota metabolism: downstream impacts on host immune function and health, and therapeutic implications. J Gastroenterol 49: 785-798, 2014.
    • (2014) J Gastroenterol , vol.49 , pp. 785-798
    • Goldsmith, J.R.1    Sartor, R.B.2
  • 46
    • 33750431077 scopus 로고    scopus 로고
    • Metabolomics as a functional genomic tool for understanding lipid dys-function in diabetes, obesity and related disorders
    • Griffin JL, Nicholls AW. Metabolomics as a functional genomic tool for understanding lipid dys-function in diabetes, obesity and related disorders. Pharmacogenomics J 7: 1095-1107, 2006.
    • (2006) Pharmacogenomics J , vol.7 , pp. 1095-1107
    • Griffin, J.L.1    Nicholls, A.W.2
  • 50
    • 0030978427 scopus 로고    scopus 로고
    • Intestinal flora and endogenous vitamin synthesis
    • Hill MJ. Intestinal flora and endogenous vitamin synthesis. Eur J Cancer Prevention 6, Suppl 1: S43-S45, 1997.
    • (1997) Eur J Cancer Prevention , vol.6 , pp. S43-S45
    • Hill, M.J.1
  • 52
    • 79959894418 scopus 로고    scopus 로고
    • Understanding the role of gut microbiome-host metabolic signal disruption in health and disease
    • Holmes E, Li JV, Athanasiou T, Ashrafian H, Nicholson JK. Understanding the role of gut microbiome-host metabolic signal disruption in health and disease. Trends Microbiol 19: 349-359, 2011.
    • (2011) Trends Microbiol , vol.19 , pp. 349-359
    • Holmes, E.1    Li, J.V.2    Athanasiou, T.3    Ashrafian, H.4    Nicholson, J.K.5
  • 53
    • 84871454511 scopus 로고    scopus 로고
    • Gut microbiota composition and activity in relation to host metabolic phenotype and disease risk
    • Holmes E, Li JV, Marchesi JR, Nicholson JK. Gut microbiota composition and activity in relation to host metabolic phenotype and disease risk. Cell Metab 16: 559-564, 2012.
    • (2012) Cell Metab , vol.16 , pp. 559-564
    • Holmes, E.1    Li, J.V.2    Marchesi, J.R.3    Nicholson, J.K.4
  • 58
    • 84862276328 scopus 로고    scopus 로고
    • Structure, function, and diversity of the healthy human microbiome
    • Human Microbiome Project Consortium
    • Human Microbiome Project Consortium. Structure, function, and diversity of the healthy human microbiome. Nature 486: 207-214, 2012.
    • (2012) Nature , vol.486 , pp. 207-214
  • 59
    • 84880924884 scopus 로고    scopus 로고
    • Metabolism: Gut microbiota modulates diurnal secretion of glucocorticoids
    • Hussain MM. Metabolism: gut microbiota modulates diurnal secretion of glucocorticoids. Nat Rev Endocrinol 9: 444-446, 2013.
    • (2013) Nat Rev Endocrinol , vol.9 , pp. 444-446
    • Hussain, M.M.1
  • 62
    • 84867658789 scopus 로고    scopus 로고
    • Intestinal commensal microbes as immune modulators
    • Ivanov II, Honda K. Intestinal commensal microbes as immune modulators. Cell Host Microbe 12: 496-508, 2012.
    • (2012) Cell Host Microbe , vol.12 , pp. 496-508
    • Ivanov, I.I.1    Honda, K.2
  • 64
    • 49649113435 scopus 로고    scopus 로고
    • Diet-induced obesity causes innate airway hyperresponsiveness to methacholine and enhances ozone-induced pulmonary inflammation
    • Johnston RA, Theman TA, Lu FL, Terry RD, Williams ES, Shore SA. Diet-induced obesity causes innate airway hyperresponsiveness to methacholine and enhances ozone-induced pulmonary inflammation. J Appl Physiol 104: 1727-1735, 2008.
    • (2008) J Appl Physiol , vol.104 , pp. 1727-1735
    • Johnston, R.A.1    Theman, T.A.2    Lu, F.L.3    Terry, R.D.4    Williams, E.S.5    Shore, S.A.6
  • 66
    • 77953163724 scopus 로고    scopus 로고
    • Onset of obesity in carboxypeptidase E-deficient mice and effect on airway responsive-ness and pulmonary responses to ozone
    • Johnston RA, Zhu M, Hernandez CB, Williams ES, Shore SA. Onset of obesity in carboxypeptidase E-deficient mice and effect on airway responsive-ness and pulmonary responses to ozone. J Appl Physiol 108: 1812-1819, 2010.
    • (2010) J Appl Physiol , vol.108 , pp. 1812-1819
    • Johnston, R.A.1    Zhu, M.2    Hernandez, C.B.3    Williams, E.S.4    Shore, S.A.5
  • 67
    • 84873528605 scopus 로고    scopus 로고
    • Role of the gut microbiota in the development and function of lymphoid cells
    • Kamada N, Nunez G. Role of the gut microbiota in the development and function of lymphoid cells. J Immunol 190: 1389-1395, 2013.
    • (2013) J Immunol , vol.190 , pp. 1389-1395
    • Kamada, N.1    Nunez, G.2
  • 68
    • 84876913132 scopus 로고    scopus 로고
    • Role of the gut microbiota in immunity and inflammatory disease
    • Kamada N, Seo SU, Chen GY, Nunez G. Role of the gut microbiota in immunity and inflammatory disease. Nat Rev Immunol 13: 321-335, 2013.
    • (2013) Nat Rev Immunol , vol.13 , pp. 321-335
    • Kamada, N.1    Seo, S.U.2    Chen, G.Y.3    Nunez, G.4
  • 73
    • 84867616398 scopus 로고    scopus 로고
    • High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway
    • Kim KA, Gu W, Lee IA, Joh EH, Kim DH. High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway. PLos One 7: e47713, 2012.
    • (2012) Plos One , vol.7
    • Kim, K.A.1    Gu, W.2    Lee, I.A.3    Joh, E.H.4    Kim, D.H.5
  • 75
    • 4544258068 scopus 로고    scopus 로고
    • NALT- versus Peyer’spatch-mediated mucosal immunity
    • Kiyono H, Fukuyama S. NALT- versus Peyer’spatch-mediated mucosal immunity. Nat Rev Immunol 4: 699-710, 2004.
    • (2004) Nat Rev Immunol , vol.4 , pp. 699-710
    • Kiyono, H.1    Fukuyama, S.2
  • 76
    • 0036279989 scopus 로고    scopus 로고
    • Mycoplasma pneumoniae and Chlamydia pneumonia in asthma: Effect of clarithromycin
    • Kraft M, Cassell GH, Pak J, Martin RJ. Mycoplasma pneumoniae and Chlamydia pneumonia in asthma: effect of clarithromycin. Chest 121: 1782-1788, 2002.
    • (2002) Chest , vol.121 , pp. 1782-1788
    • Kraft, M.1    Cassell, G.H.2    Pak, J.3    Martin, R.J.4
  • 79
    • 74249119678 scopus 로고    scopus 로고
    • Obesity and the human microbiome
    • Ley RE. Obesity and the human microbiome. Curr Opin Gastroenterol 26: 5-11, 2010.
    • (2010) Curr Opin Gastroenterol , vol.26 , pp. 5-11
    • Ley, R.E.1
  • 81
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: Human gut microbes associated with obesity
    • Ley RE, Turnbaugh PJ, Klein S, Gordon JI. Microbial ecology: human gut microbes associated with obesity. Nature 444: 1022-1023, 2006.
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 84
    • 0015450416 scopus 로고
    • Introduction to intestinal microecology
    • Luckey TD. Introduction to intestinal microecology. Am J Clin Nutr 25: 1292-1294, 1972.
    • (1972) Am J Clin Nutr , vol.25 , pp. 1292-1294
    • Luckey, T.D.1
  • 88
    • 84926679318 scopus 로고    scopus 로고
    • Induction of IL-17A precedes development of airway hyperresponsiveness during dietinduced obesity and correlates with complement factor D
    • Mathews JA, Wurmbrand AP, Ribeiro L, Neto FL, Shore SA. Induction of IL-17A precedes development of airway hyperresponsiveness during dietinduced obesity and correlates with complement factor D. Front Immunol 5: 440, 2014.
    • (2014) Front Immunol , vol.5 , pp. 440
    • Mathews, J.A.1    Wurmbrand, A.P.2    Ribeiro, L.3    Neto, F.L.4    Shore, S.A.5
  • 93
    • 0037406730 scopus 로고    scopus 로고
    • Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways
    • Miyamoto M, Prause O, Sjostrand M, Laan M, Lotvall J, Linden A. Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways. J Immunol 170: 4665-4672, 2003.
    • (2003) J Immunol , vol.170 , pp. 4665-4672
    • Miyamoto, M.1    Prause, O.2    Sjostrand, M.3    Laan, M.4    Lotvall, J.5    Linden, A.6
  • 96
    • 84940489027 scopus 로고    scopus 로고
    • Bifidobacterium pseudocatenulatum CECT 7765 reduces obesity-associated inflammation by restoring the lymphocyte-macrophage balance and gut microbiota structure in high-fat diet-fed mice
    • e0126976
    • Moya-Perez A, Neef A, Sanz Y. Bifidobacterium pseudocatenulatum CECT 7765 reduces obesity-associated inflammation by restoring the lymphocyte-macrophage balance and gut microbiota structure in high-fat diet-fed mice. PLos One 10: e0126976, 2015.
    • (2015) Plos One , vol.10
    • Moya-Perez, A.1    Neef, A.2    Sanz, Y.3
  • 99
    • 4544256857 scopus 로고    scopus 로고
    • Role of antibiotics and fungal microbiota in driving pulmonary allergic responses
    • Noverr MC, Noggle RM, Toews GB, Huffnagle GB. Role of antibiotics and fungal microbiota in driving pulmonary allergic responses. Infection Immunity 72: 4996-5003, 2004.
    • (2004) Infection Immunity , vol.72 , pp. 4996-5003
    • Noverr, M.C.1    Noggle, R.M.2    Toews, G.B.3    Huffnagle, G.B.4
  • 100
    • 62749132298 scopus 로고    scopus 로고
    • The long-term effects of breastfeeding on asthma and atopic disease
    • Oddy WH. The long-term effects of breastfeeding on asthma and atopic disease. Adv Exp Med Biol 639: 237-251, 2009.
    • (2009) Adv Exp Med Biol , vol.639 , pp. 237-251
    • Oddy, W.H.1
  • 101
    • 79959263075 scopus 로고    scopus 로고
    • The role of G-protein-coupled receptors in mediating the effect of fatty acids on inflammation and insulin sensitivity
    • Oh DY, Lagakos WS. The role of G-protein-coupled receptors in mediating the effect of fatty acids on inflammation and insulin sensitivity. Curr Opin Clin Nutr Metab Care 14: 322-327, 2011.
    • (2011) Curr Opin Clin Nutr Metab Care , vol.14 , pp. 322-327
    • Oh, D.Y.1    Lagakos, W.S.2
  • 103
    • 84865498638 scopus 로고    scopus 로고
    • Obesity and psychotic disorders: Un-covering common mechanisms through metabolomics
    • Oresic M. Obesity and psychotic disorders: un-covering common mechanisms through metabolomics. Dis Model Mech 5: 614-620, 2012.
    • (2012) Dis Model Mech , vol.5 , pp. 614-620
    • Oresic, M.1
  • 104
    • 0037190086 scopus 로고    scopus 로고
    • Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age
    • Ownby DR, Johnson CC, Peterson EL. Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age. JAMA 288: 963-972, 2002.
    • (2002) JAMA , vol.288 , pp. 963-972
    • Ownby, D.R.1    Johnson, C.C.2    Peterson, E.L.3
  • 105
    • 84875312220 scopus 로고    scopus 로고
    • Supplementation of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 in diet-induced obese mice is associated with gut microbial changes and reduction in obesity
    • Park DY, Ahn YT, Park SH, Huh CS, Yoo SR, Yu R, Sung MK, McGregor RA, Choi MS. Supplementation of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 in diet-induced obese mice is associated with gut microbial changes and reduction in obesity. PLos One 8: e59470, 2013.
    • (2013) Plos One , vol.8
    • Park, D.Y.1    Ahn, Y.T.2    Park, S.H.3    Huh, C.S.4    Yoo, S.R.5    Yu, R.6    Sung, M.K.7    McGregor, R.A.8    Choi, M.S.9
  • 109
    • 73949119670 scopus 로고    scopus 로고
    • Physiology of obesity and effects on lung function
    • Salome CM, King GG, Berend N. Physiology of obesity and effects on lung function. J Appl Physiol 108: 206-211, 2010.
    • (2010) J Appl Physiol , vol.108 , pp. 206-211
    • Salome, C.M.1    King, G.G.2    Berend, N.3
  • 110
    • 33745610880 scopus 로고    scopus 로고
    • A humanized gnotobiotic mouse model of host-archaeal-bacterial mutualism
    • Samuel BS, Gordon JI. A humanized gnotobiotic mouse model of host-archaeal-bacterial mutualism. Proc Natl Acad Sci USA 103: 10011-10016, 2006.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 10011-10016
    • Samuel, B.S.1    Gordon, J.I.2
  • 112
    • 34250161829 scopus 로고    scopus 로고
    • Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse
    • Schroeder FA, Lin CL, Crusio WE, Akbarian S. Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse. Biol Psychiatry 62: 55-64, 2007.
    • (2007) Biol Psychiatry , vol.62 , pp. 55-64
    • Schroeder, F.A.1    Lin, C.L.2    Crusio, W.E.3    Akbarian, S.4
  • 114
    • 84865474767 scopus 로고    scopus 로고
    • Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardiovascular diseases: Form and function
    • Shah SH, Kraus WE, Newgard CB. Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardiovascular diseases: form and function. Circulation 126: 1110-1120, 2012.
    • (2012) Circulation , vol.126 , pp. 1110-1120
    • Shah, S.H.1    Kraus, W.E.2    Newgard, C.B.3
  • 116
    • 84897960120 scopus 로고    scopus 로고
    • An increase in the Akkermansia spp. Population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice
    • Shin NR, Lee JC, Lee HY, Kim MS, Whon TW, Lee MS, Bae JW. An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice. Gut 63: 727-735, 2014.
    • (2014) Gut , vol.63 , pp. 727-735
    • Shin, N.R.1    Lee, J.C.2    Lee, H.Y.3    Kim, M.S.4    Whon, T.W.5    Lee, M.S.6    Bae, J.W.7
  • 117
    • 33846890411 scopus 로고    scopus 로고
    • Obesity and asthma: Lessons from animal models
    • Shore SA. Obesity and asthma: lessons from animal models. J Appl Physiol 102: 516-528, 2007.
    • (2007) J Appl Physiol , vol.102 , pp. 516-528
    • Shore, S.A.1
  • 118
    • 42749090393 scopus 로고    scopus 로고
    • Obesity and asthma: Possible mechanisms
    • quiz
    • Shore SA. Obesity and asthma: possible mechanisms. J Allergy Clin Immunol 121: 1087-1093; quiz 1094-1085, 2008.
    • (2008) J Allergy Clin Immunol , vol.121 , Issue.1087-1093 , pp. 1087-1093
    • Shore, S.A.1
  • 119
    • 77949743206 scopus 로고    scopus 로고
    • Obesity, airway hyperresponsiveness, inflammation
    • Shore SA. Obesity, airway hyperresponsiveness, inflammation. J Appl Physiol 108: 735-743, 2010.
    • (2010) J Appl Physiol , vol.108 , pp. 735-743
    • Shore, S.A.1
  • 121
    • 55449096455 scopus 로고    scopus 로고
    • No effect of metformin on the innate airway hyperresponsiveness and increased responses to ozone observed in obese mice
    • Shore SA, Williams ES, Zhu M. No effect of metformin on the innate airway hyperresponsiveness and increased responses to ozone observed in obese mice. J Appl Physiol 105: 1127-1133, 2008.
    • (2008) J Appl Physiol , vol.105 , pp. 1127-1133
    • Shore, S.A.1    Williams, E.S.2    Zhu, M.3
  • 122
    • 8344233333 scopus 로고    scopus 로고
    • Mechanisms of glucocorticoid receptor signaling during inflammation
    • Smoak KA, Cidlowski JA. Mechanisms of glucocorticoid receptor signaling during inflammation. Mech Ageing Dev 125: 697-706, 2004.
    • (2004) Mech Ageing Dev , vol.125 , pp. 697-706
    • Smoak, K.A.1    Cidlowski, J.A.2
  • 123
    • 84876414806 scopus 로고    scopus 로고
    • The gut microbiota: Masters of host development and physiology
    • Sommer F, Backhed F. The gut microbiota: masters of host development and physiology. Nat Rev Microbiol 11: 227-238, 2013.
    • (2013) Nat Rev Microbiol , vol.11 , pp. 227-238
    • Sommer, F.1    Backhed, F.2
  • 131
    • 84866168894 scopus 로고    scopus 로고
    • Functional interactions between the gut microbiota and host metabolism
    • Tremaroli V, Backhed F. Functional interactions between the gut microbiota and host metabolism. Nature 489: 242-249, 2012.
    • (2012) Nature , vol.489 , pp. 242-249
    • Tremaroli, V.1    Backhed, F.2
  • 133
    • 67849119163 scopus 로고    scopus 로고
    • The microbiome and obesity: Is obesity linked to our gut flora?
    • Tsai F, Coyle WJ. The microbiome and obesity: is obesity linked to our gut flora? Curr Gastroen-terol Rep 11: 307-313, 2009.
    • (2009) Curr Gastroen-Terol Rep , vol.11 , pp. 307-313
    • Tsai, F.1    Coyle, W.J.2
  • 134
    • 41849127118 scopus 로고    scopus 로고
    • Diet-induced obesity is linked to marked but re-versible alterations in the mouse distal gut microbiome
    • Turnbaugh PJ, Backhed F, Fulton L, Gordon JI. Diet-induced obesity is linked to marked but re-versible alterations in the mouse distal gut microbiome. Cell Host Microbe 3: 213-223, 2008.
    • (2008) Cell Host Microbe , vol.3 , pp. 213-223
    • Turnbaugh, P.J.1    Backhed, F.2    Fulton, L.3    Gordon, J.I.4
  • 137
    • 77950669604 scopus 로고    scopus 로고
    • The effect of diet on the human gut microbiome: A metagenomic analysis in humanized gnotobiotic mice
    • 6ra14
    • Turnbaugh PJ, Ridaura VK, Faith JJ, Rey FE, Knight R, Gordon JI. The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Transl Med 1: 6ra14, 2009.
    • (2009) Sci Transl Med , vol.1
    • Turnbaugh, P.J.1    Ridaura, V.K.2    Faith, J.J.3    Rey, F.E.4    Knight, R.5    Gordon, J.I.6
  • 138
    • 41749115987 scopus 로고    scopus 로고
    • Airway inflammation in obese and nonobese patients with difficult-to-treat asthma
    • van Veen IH, Ten Brinke A, Sterk PJ, Rabe KF, Bel EH. Airway inflammation in obese and nonobese patients with difficult-to-treat asthma. Allergy 63: 570-574, 2008.
    • (2008) Allergy , vol.63 , pp. 570-574
    • Van Veen, I.H.1    Ten Brinke, A.2    Sterk, P.J.3    Rabe, K.F.4    Bel, E.H.5
  • 139
    • 34547885436 scopus 로고    scopus 로고
    • Glucocorticoids, metabolismand metabolic diseases
    • Vegiopoulos A, Herzig S. Glucocorticoids, metabolism and metabolic diseases. Mol Cell Endocrinol 275: 43-61, 2007.
    • (2007) Mol Cell Endocrinol , vol.275 , pp. 43-61
    • Vegiopoulos, A.1    Herzig, S.2
  • 141
    • 77956549589 scopus 로고    scopus 로고
    • Association of childhood obesity with atopic and nonatopic asthma: Results from the National Health and Nutrition Examination Survey 1999-2006
    • Visness CM, London SJ, Daniels JL, Kaufman JS, Yeatts KB, Siega-Riz AM, Calatroni A, Zeldin DC. Association of childhood obesity with atopic and nonatopic asthma: results from the National Health and Nutrition Examination Survey 1999-2006. J Asthma 47: 822-829, 2010.
    • (2010) J Asthma , vol.47 , pp. 822-829
    • Visness, C.M.1    London, S.J.2    Daniels, J.L.3    Kaufman, J.S.4    Yeatts, K.B.5    Siega-Riz, A.M.6    Calatroni, A.7    Zeldin, D.C.8
  • 146
    • 19644401171 scopus 로고    scopus 로고
    • Taking glucocorticoids by prescription is associated with subsequent cardiovascular disease
    • Wei L, MacDonald TM, Walker BR. Taking glucocorticoids by prescription is associated with subsequent cardiovascular disease. Ann Int Med 141: 764-770, 2004.
    • (2004) Ann Int Med , vol.141 , pp. 764-770
    • Wei, L.1    Macdonald, T.M.2    Walker, B.R.3
  • 147
    • 84860679595 scopus 로고    scopus 로고
    • Asthma phenotypes: The evolution from clinical to molecular approaches
    • Wenzel SE. Asthma phenotypes: the evolution from clinical to molecular approaches. Nat Med 18: 716-725, 2012.
    • (2012) Nat Med , vol.18 , pp. 716-725
    • Wenzel, S.E.1
  • 151
    • 84862287116 scopus 로고    scopus 로고
    • Investigating potential mechanisms of obesity by metabolomics
    • Xie B, Waters MJ, Schirra HJ. Investigating potential mechanisms of obesity by metabolomics. J Biomed Biotechnol 2012: 805683, 2012.
    • (2012) J Biomed Biotechnol , vol.2012
    • Xie, B.1    Waters, M.J.2    Schirra, H.J.3
  • 153
    • 84908681868 scopus 로고    scopus 로고
    • Oral, capsulized, frozen fecal microbiota transplantation for relapsing Clostridium difficile infection
    • Youngster I, Russell GH, Pindar C, Ziv-Baran T, Sauk J, Hohmann EL. Oral, capsulized, frozen fecal microbiota transplantation for relapsing Clostridium difficile infection. JAMA 312: 1772-1778, 2014.
    • (2014) JAMA , vol.312 , pp. 1772-1778
    • Youngster, I.1    Russell, G.H.2    Pindar, C.3    Ziv-Baran, T.4    Sauk, J.5    Hohmann, E.L.6
  • 154
    • 84875050927 scopus 로고    scopus 로고
    • Power of metabolomics in biomarker discovery and mining mechanisms of obesity
    • Zhang A, Sun H, Wang X. Power of metabolomics in biomarker discovery and mining mechanisms of obesity. Obes Rev 14: 344-349, 2012.
    • (2012) Obes Rev , vol.14 , pp. 344-349
    • Zhang, A.1    Sun, H.2    Wang, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.