Increased Airway Reactivity and Hyperinsulinemia in Obese Mice Are Linked by ERK Signaling in Brain Stem Cholinergic Neurons

Cell Reports

Volumn 11, Issue 6, 2015, Pages 934-943

  Leiria, Luiz O S ^a   Arantes Costa, Fernanda M ^b   Calixto, Marina C ^a   Alexandre, Eduardo C ^a   Moura, Rodrigo F ^a   Folli, Franco ^a,c   Prado, Carla M ^d   Prado, Marco Antonio ^e   Prado, Vania F ^e   Velloso, Licio A ^a   Donato, José ^b   Antunes, Edson ^a   Martins, Milton A ^b   Saad, Mario J A ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c Mays Cancer Center at UT Health San Antonio   (United States)

^d FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^e ROBARTS RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; INSULIN RECEPTOR; METHACHOLINE CHLORIDE; PHOSPHATIDYLINOSITOL 3 KINASE;

AMBIGUUS NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; CELL INFILTRATION; CHOLINERGIC NERVE CELL; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVATION; HYPERINSULINEMIA; INFLAMMATORY CELL; MALE; MOTONEURON NUCLEUS; MOUSE; NONHUMAN; OBESITY; PATHOGENESIS; PRIORITY JOURNAL; RESPIRATORY TRACT ALLERGY; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL; BRAIN STEM; BRONCHOCONSTRICTION; BRONCHUS HYPERREACTIVITY; C57BL MOUSE; COMPLICATION; ENZYMOLOGY; HYPERINSULINISM; INFLAMMATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; LIPID DIET; METABOLISM; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION;

MUS;

ANIMALS; BRAIN STEM; BRONCHIAL HYPERREACTIVITY; BRONCHOCONSTRICTION; CHOLINERGIC NEURONS; DIET, HIGH-FAT; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HYPERINSULINISM; INFLAMMATION; INJECTIONS, INTRAVENTRICULAR; INSULIN; MAP KINASE SIGNALING SYSTEM; METHACHOLINE CHLORIDE; MICE, INBRED C57BL; MICE, OBESE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; RECEPTOR, INSULIN;

EID: 84929261938     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.04.012     Document Type: Article

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