A γ-secretase independent role for presenilin in calcium homeostasis impacts mitochondrial function and morphology in caenorhabditis elegans

Genetics

Volumn 201, Issue 4, 2015, Pages 1453-1466

  Sarasija, Shaarika ^a   Norman, Kenneth R ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

Author keywords

Caenorhabditis elegans; Calcium; Endoplasmic reticulum; Mitochondria; Presenilin

Indexed keywords

CALCIUM; GAMMA SECRETASE; LEVAMISOLE; MEMBRANE PROTEIN; NOTCH RECEPTOR; PRESENILIN; SEL 12; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; SECRETASE; SEL-12 PROTEIN, C ELEGANS;

ADULT; AMYLOID PLAQUE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CAENORHABDITIS ELEGANS; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CELL FUNCTION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; DNA FRAGMENTATION; ENDOPLASMIC RETICULUM; GENE FUNCTION; GENE MUTATION; GENETIC ANALYSIS; MITOCHONDRION; MOLECULAR BIOLOGY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; YOUNG ADULT; ANIMAL; GENETICS; HOMEOSTASIS; HUMAN; METABOLISM; MUTATION; PHYSIOLOGY; ULTRASTRUCTURE;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CALCIUM; ENDOPLASMIC RETICULUM; HOMEOSTASIS; HUMANS; MEMBRANE PROTEINS; MITOCHONDRIA; MUTATION; PRESENILINS;

EID: 84957827652     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.115.182808     Document Type: Article

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