Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4

Nature Communications

Volumn 7, Issue , 2016, Pages

  Hartmann, Petra ^a   Zhou, Zhe ^b   Natarelli, Lucia ^a   Wei, Yuanyuan ^a,c   Nazari Jahantigh, Maliheh ^a,c   Zhu, Mengyu ^a   Grommes, Jochen ^b,d   Steffens, Sabine ^a,c   Weber, Christian ^a,c   Schober, Andreas ^a,b,c  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^d MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; CXCL1 CHEMOKINE; DICER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KRUPPEL LIKE FACTOR 4; MICRORNA; MICRORNA 103; UNCLASSIFIED DRUG; CXCL1 PROTEIN, HUMAN; CXCL1 PROTEIN, MOUSE; DEAD BOX PROTEIN; DICER1 PROTEIN, HUMAN; DICER1 PROTEIN, MOUSE; KRUPPEL LIKE FACTOR; MIRN103 MICRORNA, HUMAN; MIRN103 MICRORNA, MOUSE; RIBONUCLEASE III; TRANSCRIPTOME;

ADHESION; BLOOD; CARDIOVASCULAR DISEASE; CELLS AND CELL COMPONENTS; GENE; GENE EXPRESSION; INHIBITION; RODENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAROTID ATHEROSCLEROSIS; CELL ADHESION; CELL FUNCTION; CONTROLLED STUDY; ENDOTHELIUM CELL; EX VIVO STUDY; FEMALE; GENE EXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LIPID DIET; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; VASCULAR ENDOTHELIUM; VASCULITIS; ANIMAL; AORTA; ATHEROSCLEROSIS; CAROTID ARTERY; CAROTID ENDARTERECTOMY; CELL CULTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION PROFILING; GENETICS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; KNOCKOUT MOUSE; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING;

MURINAE; MUS;

ANIMALS; AORTA; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BLOTTING, WESTERN; CAROTID ARTERIES; CELL ADHESION; CELLS, CULTURED; CHEMOKINE CXCL1; DEAD-BOX RNA HELICASES; DIET, HIGH-FAT; ENDARTERECTOMY, CAROTID; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION PROFILING; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MACROPHAGES; MICE; MICE, KNOCKOUT; MICRORNAS; MONOCYTES; NF-KAPPA B; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBONUCLEASE III; TRANSCRIPTOME; VASCULITIS;

EID: 84957590706     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10521     Document Type: Article

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