In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 3, 2015, Pages 767-772

  La Rocca, Gaspare ^a   Olejniczak, Scott H ^a   González, Alvaro J ^a   Briskin, Daniel ^a   Vidigal, Joana A ^a   Spraggon, Lee ^a   DeMatteo, Raymond G ^a   Radler, Megan R ^a   Lindsten, Tullia ^b   Ventura, Andrea ^a   Tuschl, Thomas ^a   Leslie, Christina S ^a   Thompson, Craig B ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Argonaute; GW182; MicroRNA; MTOR; T cells

Indexed keywords

ARGONAUTE PROTEIN; INTERLEUKIN 3; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MICRORNA; PHOSPHATIDYLINOSITOL 3 KINASE; POLYADENYLIC ACID BINDING PROTEIN; PROTEIN KINASE B; RAC PROTEIN; RNA INDUCED SILENCING COMPLEX; S6 KINASE;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; COMPLEX FORMATION; GENE REPRESSION; GENE TARGETING; HEMATOPOIETIC CELL; IN VIVO STUDY; INTRACELLULAR SIGNALING; MOLECULAR WEIGHT; MOUSE; NON-TRANSFORMED CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN STABILITY; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; LYMPHOCYTE ACTIVATION; METABOLISM;

ARGONAUTE PROTEINS; LYMPHOCYTE ACTIVATION; MICRORNAS; MOLECULAR WEIGHT; RNA, MESSENGER; T-LYMPHOCYTES;

EID: 84922422451     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1424217112     Document Type: Article

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