Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Liu, Jian ^a   Copland, David A ^a   Theodoropoulou, Sofia ^a   Chiu, Hsi An Amy ^a   Barba, Miriam Durazo ^a   Mak, Ka Wang ^a   Mack, Matthias ^b   Nicholson, Lindsay B ^a   Dick, Andrew D ^a,c,d  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d The National Institute for Health Research Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections at University College London in partnership with UK Health Security Agency   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; INFLAMMASOME; ROTENONE;

ANIMAL; AUTOPHAGY; CELL CULTURE; COCULTURE; CYTOLOGY; IMMUNOLOGY; MACROPHAGE; MACULAR DEGENERATION; METABOLISM; MOUSE; PATHOLOGY; RETINAL PIGMENT EPITHELIUM; SUBRETINAL NEOVASCULARIZATION;

ANIMALS; AUTOPHAGY; CASPASE 3; CELLS, CULTURED; CHOROIDAL NEOVASCULARIZATION; COCULTURE TECHNIQUES; INFLAMMASOMES; MACROPHAGES; MACULAR DEGENERATION; MICE; RETINAL PIGMENT EPITHELIUM; ROTENONE;

EID: 84957590674     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep20639     Document Type: Article

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