-
1
-
-
84929375988
-
20th Anniversary Special Report
-
Alliance for Eye and Vision Research (2013) 20th Anniversary Special Report. October, 2013. http://www.eyeresearch.org/pdf/ValueBrochure/ Value_of_Vision_Research_Brochure_Page_l.pdf.
-
(2013)
October, 2013
-
-
Alliance for Eye and Vision Research1
-
2
-
-
0034431467
-
Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction
-
CrossRef Medline
-
Ayala-Torres S, Chen Y, Svoboda T, Rosenblatt J, Van Houten B (2000) Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction. Methods 22:135-147. CrossRef Medline
-
(2000)
Methods
, vol.22
, pp. 135-147
-
-
Ayala-Torres, S.1
Chen, Y.2
Svoboda, T.3
Rosenblatt, J.4
Van Houten, B.5
-
4
-
-
0036570012
-
Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells
-
CrossRef Medline
-
Bohr VA (2002) Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells. Free Radic Biol Med 32:804-812. CrossRef Medline
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 804-812
-
-
Bohr, V.A.1
-
5
-
-
84929458917
-
The baby boom cohort in the United States: 2012 to 2060
-
US Census Bureau, Washington, DC
-
Colby SL, Ortman JM (2014) The baby boom cohort in the United States: 2012 to 2060. Current Population Reports. US Census Bureau, Washington, DC: P25-1141.
-
(2014)
Current Population Reports
, pp. P25-P1141
-
-
Colby, S.L.1
Ortman, J.M.2
-
6
-
-
70350422838
-
Aging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins
-
CrossRef Medline
-
Curcio CA, Johnson M, Huang JD, Rudolf M (2009) Aging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins. Prog Retin Eye Res 28:393-422. CrossRef Medline
-
(2009)
Prog Retin Eye Res
, vol.28
, pp. 393-422
-
-
Curcio, C.A.1
Johnson, M.2
Huang, J.D.3
Rudolf, M.4
-
7
-
-
33947383078
-
Changes in select redox proteins of the retinal pigment epithelium in age-related macular degeneration
-
CrossRef Medline
-
Decanini A, Nordgaard CL, Feng X, Ferrington DA, Olsen TW (2007) Changes in select redox proteins of the retinal pigment epithelium in age-related macular degeneration. Am J Ophthalmol 143:607-615. CrossRef Medline
-
(2007)
Am J Ophthalmol
, vol.143
, pp. 607-615
-
-
Decanini, A.1
Nordgaard, C.L.2
Feng, X.3
Ferrington, D.A.4
Olsen, T.W.5
-
8
-
-
0028342951
-
Repair of oxidative damage to DNA: Enzymol-ogy and biology
-
CrossRef Medline
-
Demple B, Harrison L (1994) Repair of oxidative damage to DNA: enzymol-ogy and biology. Annu Rev Biochem 63:915-948. CrossRef Medline
-
(1994)
Annu Rev Biochem
, vol.63
, pp. 915-948
-
-
Demple, B.1
Harrison, L.2
-
9
-
-
34249104544
-
Oxidative stress and aberrant signaling in aging and cognitive decline
-
CrossRef Medline
-
Droge W, Schipper HM (2007) Oxidative stress and aberrant signaling in aging and cognitive decline. Aging Cell 6:361-370. CrossRef Medline
-
(2007)
Aging Cell
, vol.6
, pp. 361-370
-
-
Droge, W.1
Schipper, H.M.2
-
10
-
-
33745650321
-
The proteome of central and peripheral retina with progression of age-related macular degeneration
-
CrossRef Medline
-
Ethen CM, Reilly C, Feng X, Olsen TW, Ferrington DA (2006) The proteome of central and peripheral retina with progression of age-related macular degeneration. Invest Ophthalmol Vis Sci 47:2280-2290. CrossRef Medline
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 2280-2290
-
-
Ethen, C.M.1
Reilly, C.2
Feng, X.3
Olsen, T.W.4
Ferrington, D.A.5
-
11
-
-
33746406453
-
Mitochondrial alterations of retinal pigment epithelium in age-related macular degeneration
-
CrossRef Medline
-
Feher J, Kovacs I, Artico M Cavallotti C, Papale A, Balacco Gabrieli C (2006) Mitochondrial alterations of retinal pigment epithelium in age-related macular degeneration. Neurobiol Aging 27:983-993. CrossRef Medline
-
(2006)
Neurobiol Aging
, vol.27
, pp. 983-993
-
-
Feher, J.1
Kovacs, I.2
Artico, M.3
Cavallotti, C.4
Papale, A.5
Balacco Gabrieli, C.6
-
12
-
-
0032992736
-
Antioxidant enzymes in the macular retinal pigment epithelium of eyes with neovascular age-related macular degeneration
-
CrossRef Medline
-
Frank RN, Amin RH, Puklin JE (1999) Antioxidant enzymes in the macular retinal pigment epithelium of eyes with neovascular age-related macular degeneration. Am J Ophthalmol 127:694-709. CrossRef Medline
-
(1999)
Am J Ophthalmol
, vol.127
, pp. 694-709
-
-
Frank, R.N.1
Amin, R.H.2
Puklin, J.E.3
-
13
-
-
11144354339
-
Eye diseases prevalence research group: Prevalence of age-related macular degeneration in the United States
-
CrossRef Medline
-
Friedman DS, O'Colmain BJ, Muñoz B, Tomany SC, McCarty C, de Jong PT, Nemesure B, Mitchell P, Kempen J (2004) Eye diseases prevalence research group: prevalence of age-related macular degeneration in the United States. Arch Ophthalmol 122:564-572. CrossRef Medline
-
(2004)
Arch Ophthalmol
, vol.122
, pp. 564-572
-
-
Friedman, D.S.1
O'Colmain, B.J.2
Muñoz, B.3
Tomany, S.C.4
McCarty, C.5
de Jong, P.T.6
Nemesure, B.7
Mitchell, P.8
Kempen, J.9
-
14
-
-
84874329875
-
The 3895-bp mitochondrial DNA deletion in the human eye: A potential involvement in corneal ageing and macular degeneration
-
CrossRef Medline
-
Gendron SP, Bastien N, Mallet JD, Rochette PJ (2013) The 3895-bp mitochondrial DNA deletion in the human eye: a potential involvement in corneal ageing and macular degeneration. Mutagenesis 28:197-204. CrossRef Medline
-
(2013)
Mutagenesis
, vol.28
, pp. 197-204
-
-
Gendron, S.P.1
Bastien, N.2
Mallet, J.D.3
Rochette, P.J.4
-
15
-
-
84863722159
-
How does the macula protect itself from oxidative stress?
-
CrossRef Medline
-
Handa JT (2012) How does the macula protect itself from oxidative stress? Mol Aspects Med 33:418-435. CrossRef Medline
-
(2012)
Mol Aspects Med
, vol.33
, pp. 418-435
-
-
Handa, J.T.1
-
16
-
-
78650938849
-
Mitochondrial DNA damage as a potential mechanism for age-related macular degeneration
-
CrossRef Medline
-
Karunadharma PP, Nordgaard CL, Olsen TW, Ferrington DA (2010) Mitochondrial DNA damage as a potential mechanism for age-related macular degeneration. Invest Ophthalmol Vis Sci 51:5470-5479. CrossRef Medline
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 5470-5479
-
-
Karunadharma, P.P.1
Nordgaard, C.L.2
Olsen, T.W.3
Ferrington, D.A.4
-
17
-
-
67651097456
-
Analysis of oxidative damage by gene-specific quantitative PCR
-
CrossRef Medline
-
Kovalenko OA, Santos JH (2009) Analysis of oxidative damage by gene-specific quantitative PCR. Curr Protoc Hum Genet 19:1. CrossRef Medline
-
(2009)
Curr Protoc Hum Genet
, vol.19
, pp. 1
-
-
Kovalenko, O.A.1
Santos, J.H.2
-
18
-
-
0019020390
-
The Framingham eye study monograph: An ophthalmological and epidemiological study of cataract, glaucoma, diabetic retinopathy, and macular degeneration, and visual acuity in the general population of 2631 adults, 1973-1975
-
CrossRef Medline
-
Leibowitz HM, Krueger DE, Maunder LR, Milton RC, Kini MM, Kahn HA, Nickerson RJ, Pool J, Colton TL, Ganley JP, Loewenstein JI, Dawber TR (1980) The Framingham eye study monograph: an ophthalmological and epidemiological study of cataract, glaucoma, diabetic retinopathy, and macular degeneration, and visual acuity in the general population of 2631 adults, 1973-1975. Surv Ophthalmol 24:335-610. CrossRef Medline
-
(1980)
Surv Ophthalmol
, vol.24
, pp. 335-610
-
-
Leibowitz, H.M.1
Krueger, D.E.2
Maunder, L.R.3
Milton, R.C.4
Kini, M.M.5
Kahn, H.A.6
Nickerson, R.J.7
Pool, J.8
Colton, T.L.9
Ganley, J.P.10
Loewenstein, J.I.11
Dawber, T.R.12
-
19
-
-
0025824572
-
Antioxidant enzymes in the aging human retinal pigment epithelium
-
CrossRef Medline
-
Liles MR, Newsome DA, Oliver PD (1991) Antioxidant enzymes in the aging human retinal pigment epithelium. Arch Ophthalmol 109:1285-1288. CrossRef Medline
-
(1991)
Arch Ophthalmol
, vol.109
, pp. 1285-1288
-
-
Liles, M.R.1
Newsome, D.A.2
Oliver, P.D.3
-
20
-
-
80051749739
-
Mitochondrial DNA damage and repair in RPE associated with aging and age-related macular degeneration
-
CrossRef Medline
-
Lin H, Xu H, Liang FQ, Liang H, Gupta P, Havey AN, Boulton ME, Godley BF (2011) Mitochondrial DNA damage and repair in RPE associated with aging and age-related macular degeneration. Invest Ophthalmol Vis Sci 52:3521-3529. CrossRef Medline
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 3521-3529
-
-
Lin, H.1
Xu, H.2
Liang, F.Q.3
Liang, H.4
Gupta, P.5
Havey, A.N.6
Boulton, M.E.7
Godley, B.F.8
-
21
-
-
84919740196
-
Dysregulated au-tophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD
-
CrossRef Medline
-
Mitter SK, Song C, Qi X, Mao H, Rao H, Akin D, Lewin A, Grant M, Dunn W Jr, Ding J, Bowes Rickman C, Boulton M (2014) Dysregulated au-tophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD. Autophagy 10:1989-2005. CrossRef Medline
-
(2014)
Autophagy
, vol.10
, pp. 1989-2005
-
-
Mitter, S.K.1
Song, C.2
Qi, X.3
Mao, H.4
Rao, H.5
Akin, D.6
Lewin, A.7
Grant, M.8
Dunn, W.9
Ding, J.10
Bowes Rickman, C.11
Boulton, M.12
-
22
-
-
33645401537
-
Proteomics of the retinal pigment epithelium reveals altered protein expression at progressive stages of age-related macular degeneration
-
CrossRef Medline
-
Nordgaard CL, Berg KM, Kapphahn RJ, Reilly C, Feng X, Olsen TW, Ferrington DA (2006) Proteomics of the retinal pigment epithelium reveals altered protein expression at progressive stages of age-related macular degeneration. Invest Ophthalmol Vis Sci 47:815-822. CrossRef Medline
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 815-822
-
-
Nordgaard, C.L.1
Berg, K.M.2
Kapphahn, R.J.3
Reilly, C.4
Feng, X.5
Olsen, T.W.6
Ferrington, D.A.7
-
23
-
-
48249104648
-
Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration
-
CrossRef Medline
-
Nordgaard CL, Karunadharma PP, Feng X, Olsen TW, Ferrington DA (2008) Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration. Invest Ophthalmol Vis Sci 49:2848-2855. CrossRef Medline
-
(2008)
Invest Ophthalmol Vis Sci
, vol.49
, pp. 2848-2855
-
-
Nordgaard, C.L.1
Karunadharma, P.P.2
Feng, X.3
Olsen, T.W.4
Ferrington, D.A.5
-
24
-
-
9444225094
-
The Minnesota grading system of eye bank eyes for age-related macular degeneration
-
CrossRef Medline
-
Olsen TW, Feng X (2004) The Minnesota grading system of eye bank eyes for age-related macular degeneration. Invest Ophthalmol Vis Sci 45: 4484-4490. CrossRef Medline
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, pp. 4484-4490
-
-
Olsen, T.W.1
Feng, X.2
-
25
-
-
0023811053
-
Normal oxidative damage to mitochondrial and nuclear DNA is extensive
-
CrossRef Medline
-
Richter C, Park JW, Ames BN (1988) Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc Natl Acad Sci U S A 85: 6465-6467. CrossRef Medline
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 6465-6467
-
-
Richter, C.1
Park, J.W.2
Ames, B.N.3
-
26
-
-
65749108269
-
Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration
-
CrossRef Medline
-
SanGiovanni JP, Arking DE, Iyengar SK, Elashoff M, Clemons TE, Reed GF, Henning AK, Sivakumaran TA, Xu X, DeWan A, Agrón E, Rochtchina E, Sue CM, Wang JJ, Mitchell P, Hoh J, Francis PJ, Klein ML, Chew EY, Chakravarti A (2009) Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration. PLoS One 4:e5508. CrossRef Medline
-
(2009)
PLoS One
, vol.4
-
-
SanGiovanni, J.P.1
Arking, D.E.2
Iyengar, S.K.3
Elashoff, M.4
Clemons, T.E.5
Reed, G.F.6
Henning, A.K.7
Sivakumaran, T.A.8
Xu, X.9
DeWan, A.10
Agrón, E.11
Rochtchina, E.12
Sue, C.M.13
Wang, J.J.14
Mitchell, P.15
Hoh, J.16
Francis, P.J.17
Klein, M.L.18
Chew, E.Y.19
Chakravarti, A.20
more..
-
27
-
-
0036355070
-
Measuring oxidative mtDNA damage and repair using quantitative PCR
-
CrossRef Medline
-
Santos JH, Mandavilli BS, Van Houten B (2002) Measuring oxidative mtDNA damage and repair using quantitative PCR. Methods Mol Biol 197:159-176. CrossRef Medline
-
(2002)
Methods Mol Biol
, vol.197
, pp. 159-176
-
-
Santos, J.H.1
Mandavilli, B.S.2
Van Houten, B.3
-
28
-
-
13844272923
-
Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage
-
CrossRef Medline
-
Santos JH, Meyer JN, Skorvaga M, Annab LA, Van Houten B (2004) Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage. Aging Cell 3:399-411. CrossRef Medline
-
(2004)
Aging Cell
, vol.3
, pp. 399-411
-
-
Santos, J.H.1
Meyer, J.N.2
Skorvaga, M.3
Annab, L.A.4
Van Houten, B.5
-
29
-
-
21244451958
-
The retinal pigment epithelium in visual function
-
CrossRef Medline
-
Strauss O (2005) The retinal pigment epithelium in visual function. Physiol Rev 85:845-881. CrossRef Medline
-
(2005)
Physiol Rev
, vol.85
, pp. 845-881
-
-
Strauss, O.1
-
30
-
-
0035432034
-
The determination of complete human mitochondrial DNA sequences in single cells: Implications for the study of somatic mitochondrial DNA point mutations
-
CrossRef Medline
-
Taylor RW, Taylor GA, Durham SE, Turnbull DM (2001) The determination of complete human mitochondrial DNA sequences in single cells: implications for the study of somatic mitochondrial DNA point mutations. Nucleic Acids Res 29:E74-4. CrossRef Medline
-
(2001)
Nucleic Acids Res
, vol.29
, pp. E74-E84
-
-
Taylor, R.W.1
Taylor, G.A.2
Durham, S.E.3
Turnbull, D.M.4
-
31
-
-
66849130909
-
Mitochondrial DNA haplogroups associated with age-related macular degeneration
-
CrossRef Medline
-
Udar N, Atilano SR, Memarzadeh M, Boyer DS, Chwa M, Lu S, Maguen B, Langberg J, Coskun P, Wallace DC, Nesburn AB, Khatibi N, Hertzog D, Le K, Hwang D, Kenney MC (2009) Mitochondrial DNA haplogroups associated with age-related macular degeneration. Invest Ophthalmol Vis Sci 50:2966-2974. CrossRef Medline
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, pp. 2966-2974
-
-
Udar, N.1
Atilano, S.R.2
Memarzadeh, M.3
Boyer, D.S.4
Chwa, M.5
Lu, S.6
Maguen, B.7
Langberg, J.8
Coskun, P.9
Wallace, D.C.10
Nesburn, A.B.11
Khatibi, N.12
Hertzog, D.13
Le, K.14
Hwang, D.15
Kenney, M.C.16
-
32
-
-
84880843826
-
Autophagy activation clears ELAVLl/HuR-mediated accumulation of SQSTMl/p62 during proteasomal inhibition in human retinal pigment epithelial cells
-
CrossRef Medline
-
Viiri J, Amadio M, Marchesi N, Hyttinen JM, Kivinen N, Sironen R, Rilla K, Akhtar S, Provenzani A, D'Agostino VG, Govoni S, Pascale A, Agostini H, Petrovski G, Salminen A, Kaarniranta K (2013) Autophagy activation clears ELAVLl/HuR-mediated accumulation of SQSTMl/p62 during proteasomal inhibition in human retinal pigment epithelial cells. PLoS One 8:e69563. CrossRef Medline
-
(2013)
PLoS One
, vol.8
-
-
Viiri, J.1
Amadio, M.2
Marchesi, N.3
Hyttinen, J.M.4
Kivinen, N.5
Sironen, R.6
Rilla, K.7
Akhtar, S.8
Provenzani, A.9
D'Agostino, V.G.10
Govoni, S.11
Pascale, A.12
Agostini, H.13
Petrovski, G.14
Salminen, A.15
Kaarniranta, K.16
-
33
-
-
84873390153
-
The emerging role of the mitochondrial-derived peptide humanin in stress resistance
-
CrossRef Medline
-
Yen K, Lee C, Mehta H, Cohen P (2013) The emerging role of the mitochondrial-derived peptide humanin in stress resistance. J Mol Endocrinol 50:R11-R9. CrossRef Medline
-
(2013)
J Mol Endocrinol
, vol.50
, pp. R11-R19
-
-
Yen, K.1
Lee, C.2
Mehta, H.3
Cohen, P.4
|