Characterization of a spontaneous mouse retinal pigment epithelial cell line B6-RPE07

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 8, 2008, Pages 3699-3706

  Chen, Mei ^a   Muckersie, Elizabeth ^a   Robertson, Marie ^a   Fraczek, Monika ^a   Forrester, John V ^a   Xu, Heping ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CHEMOKINE; CLAUDIN 1; CLAUDIN 3; COLLAGEN GEL; CYTOKERATIN; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; OCCLUDIN; PROTEIN ZO1; RETINOID BINDING PROTEIN; 11 CIS RETINAL BINDING PROTEIN; 11-CIS-RETINAL-BINDING PROTEIN; BIOLOGICAL MARKER; CARRIER PROTEIN; CYTOKINE; EYE PROTEIN; RPE65 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD RETINA BARRIER; CELL CLONING; CELL FUNCTION; CELL MEMBRANE; CELL STRUCTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RELEASE; ELECTRON MICROSCOPY; EPITHELIUM CELL; FEMALE; FLOW CYTOMETRY; FLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MICROVILLUS; MOUSE; NONHUMAN; PHAGOCYTOSIS; PHASE CONTRAST MICROSCOPY; PHENOTYPE; PHOTORECEPTOR; PIGMENT EPITHELIUM; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL LINE; CELL SEPARATION; CULTURE TECHNIQUE; CYTOLOGY; METABOLISM; PHYSIOLOGY; RETINA ROD OUTER SEGMENT; ULTRASTRUCTURE;

ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CARRIER PROTEINS; CELL CULTURE TECHNIQUES; CELL LINE; CELL SEPARATION; CYTOKINES; EYE PROTEINS; FEMALE; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MICROSCOPY, PHASE-CONTRAST; PHAGOCYTOSIS; PHENOTYPE; PIGMENT EPITHELIUM OF EYE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; ROD OUTER SEGMENTS;

EID: 49049087553     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.07-1522     Document Type: Article

References (59)

1. Schraermeyer U, Heimann K. Current understanding on the role of retinal pigment epithelium and its pigmentation. Pigment Cell Res. 1999;12:219-236.
2. Young RW. The renewal of photoreceptor cell outer segments. J Cell Biol. 1967;33:61-72.
3. Bosch E, Horwitz J, Bok D. Phagocytosis of outer segments by retinal pigment epithelium: phagosome-lysosome interaction. J Histochem Cytochem. 1993;41:253-263.
4. Zamiri P, Masli S, Kitaichi N, Taylor AW, Streilein JW. Thrombospondin plays a vital role in the immune privilege of the eye. Invest Ophthalmol Vis Sci. 2005;46:908-919.
5. Zamiri P, Sugita S, Streilein JW. Immunosuppressive properties of the pigmented epithelial cells and the subretinal space. Chem Immunol Allergy. 2007;92:86-93.
6. Liversidge J, Dawson R, Hoey S, McKay D, Grabowski P, Forrester JV. CD59 and CD48 expressed by rat retinal pigment epithelial cells are major ligands for the CD2-mediated alternative pathway of T cell activation. J Immunol. 1996;156:3696-3703.
7. Chen M, Forrester JV, Xu H. Synthesis of complement factor H by retinal pigment epithelial cells is down-regulated by oxidized photoreceptor outer segments. Exp Eye Res. 2007;84:635-645.
8. Goureau O, Amiot F, Dautry F, Courtois Y. Control of nitric oxide production by endogenous TNF-alpha in mouse retinal pigmented epithelial and Muller glial cells. Biochem Biophys Res Commun. 1997;240:132-135.
9. Crane IJ, Wallace CA, McKillop-Smith S, Forrester JV. Control of chemokine production at the blood-retina barrier. Immunology. 2000;101:426-433.
10. Crane IJ, Wallace CA, Forrester JV. Regulation of granulocytemacrophage colony-stimulating factor in human retinal pigment epithelial cells by IL-1β and IFN-γ. Cell Immunol. 2001;209:132-139.
11. Elner SG, Strieter RM, Elner VM, Rollins BJ, Del Monte MA, Kunkel SL. Monocyte chemotactic protein gene expression by cytokine-treated human retinal pigment epithelial cells. Lab Invest. 1991;64:819-825.
12. Holtkamp GM, De Vos AF, Peek R, Kijlsta A. Analysis of the secretion pattern of monocyte chemotactic protein-1 (MCP-1) and transforming growth factor-beta 2 (TGF-beta2) by human retinal pigment epithelial cells. Clin Exp Immunol. 1999;118:35-40.
13. Hageman GS, Anderson DH, Johnson LV, et al. From the cover: a common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A. 2005;102:7227-7232.
14. Mandal MN, Ayyagari R. Complement factor H: spatial and temporal expression and localization in the eye. Invest Ophthalmol Vis Sci. 2006;47:4091-4097.
15. Lutty G, Grunwald J, Majji AB, Uyama M, Yoneya S. Changes in choriocapillaris and retinal pigment epithelium in age-related macular degeneration. Mol Vis. 1999;5:35.
16. Litchfield TM, Whiteley SJ, Lund RD. Transplantation of retinal pigment epithelial, photoreceptor and other cells as treatment for retinal degeneration. Exp Eye Res. 1997;64:655-666.
17. Kaplan HJ, Tezel TH, Del Priore LV. Retinal pigment epithelial transplantation in age-related macular degeneration. Retina. 1998;18:99-102.
18. Binder S, Krebs I, Hilgers RD, et al. Outcome of transplantation of autologous retinal pigment epithelium in age-related macular degeneration: a prospective trial. Invest Ophthalmol Vis Sci. 2004;45:4151-4160.
19. Joussen AM, Heussen FM, Joeres S, et al. Autologous translocation of the choroid and retinal pigment epithelium in age-related macular degeneration. Am J Ophthalmol. 2006;142:17-30.
20. MacLaren RE, Uppal GS, Balaggan KS, et al. Autologous transplantation of the retinal pigment epithelium and choroid in the treatment of neovascular age-related macular degeneration. Ophthalmology. 2007;114:561-570.
21. Heussen FM, Fawzy NF, Joeres S, et al. Autologous translocation of the choroid and RPE in age-related macular degeneration: 1-year follow-up in 30 patients and recommendations for patient selection. Eye. 2008;22(6):799-807.
22. Elner VM, Strieter RM, Elner SG, Baggiolini M, Lindley I, Kunkel SL. Neutrophil chemotactic factor (IL-8) gene expression by cytokine-treated retinal pigment epithelial cells. Am J Pathol. 1990;136: 745-750.
23. Elner VM, Scales W, Elner SG, Danforth J, Kunkel SL, Strieter RM. Interleukin-6 (IL-6) gene expression and secretion by cytokine-stimulated human retinal pigment epithelial cells. Exp Eye Res. 1992;54:361-368.
24. Crane IJ, Kuppner MC, McKillop-Smith S, Wallace CA, Forrester JV. Cytokine regulation of granulocyte-macrophage colony-stimulating factor (GM-CSF) production by human retinal pigment epithelial cells. Clin Exp Immunol. 1999;115:288-293.
25. Fukuoka Y, Strainic M, Medof ME. Differential cytokine expression of human retinal pigment epithelial cells in response to stimulation by C5a. Clin Exp Immunol. 2003;131:248-253.
26. Bian ZM, Elner SG, Strieter RM, et al. Glycated serum albumin induces chemokine gene expression in human retinal pigment epithelial cells. J Leukoc Biol. 1996;60:405-414.
27. Bian ZM, Elner SG, Yoshida A, Kunkel SL, Su J, Elner VM. Activation of p38, ERK1/2 and NIK pathways is required for IL-1beta and TNF-alpha-induced chemokine expression in human retinal pigment epithelial cells. Exp Eye Res. 2001;73:111-121.
28. Newsome DA. Retinal pigmented epithelium culture: current applications. Trans Ophthalmol Soc UK. 1983;103(pt 4):458-466.
29. Peng S, Rahner C, Rizzolo LJ. Apical and basal regulation of the permeability of the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2003;44:808-817.
30. Luo Y, Fukuhara M, Weitzman M, Rizzolo LJ. Expression of JAM-A, AF-6, PAR-3 and PAR-6 during the assembly and remodeling of RPE tight junctions. Brain Res. 2006;1110:55-63.
31. Essner E, Roszka JR, Schreiber JH. Phagocytosis and surface morphology in cultured retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1978;17:1040-1048.
32. Mayerson PL, Hall MO. Rat retinal pigment epithelial cells show specificity of phagocytosis in vitro. J Cell Biol. 1986;103:299-308.
33. McLaren MJ. Kinetics of rod outer segment phagocytosis by cultured retinal pigment epithelial cells: relationship to cell morphology. Invest Ophthalmol Vis Sci. 1996;37:1213-1224.
34. Karihaloo A, Kato K, Greene DA, Thomas TP. Protein kinase and Ca2+ modulation of myo-inositol transport in cultured retinal pigment epithelial cells. Am J Physiol. 1997;273:C671-C678.
35. Ban Y, Rizzolo LJ. Regulation of glucose transporters during development of the retinal pigment epithelium. Brain Res Dev Brain Res. 2000;121:89-95.
36. Davis AA, Bernstein PS, Bok D, Turner J, Nachtigal M, Hunt RC. A human retinal pigment epithelial cell line that retains epithelial characteristics after prolonged culture. Invest Ophthalmol Vis Sci. 1995;36:955-964.
37. Dunn KC, Aotaki-Keen AE, Putkey FR, Hjelmeland LM. ARPE-19, a human retinal pigment epithelial cell line with differentiated properties. Exp Eye Res. 1996;62:155-169.
38. McLaren MJ, Sasabe T, Li CY, Brown ME, Inana G. Spontaneously arising immortal cell line of rat retinal pigmented epithelial cells. Exp Cell Res. 1993;204:311-320.
39. Nabi IR, Mathews AP, Cohen-Gould L, Gundersen D, Rodriguez-Boulan E. Immortalization of polarized rat retinal pigment epithelium. J Cell Sci. 1993;104(pt 1):37-49.
40. Liversidge JM, Sewell HF, Forrester JV. Human retinal pigment epithelial cells differentially express MHC class II (HLA, DP, DR and DQ) antigens in response to in vitro stimulation with lymphokine or purified IFN-gamma. Clin Exp Immunol. 1988;73:489-494.
41. Doyle JW, Dowgiert RK, Buzney SM. Retinoic acid metabolism in cultured retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1995;36:708-717.
42. Molday RS, Molday LL. Differences in the protein composition of bovine retinal rod outer segment disk and plasma membranes isolated by a ricin-gold-dextran density perturbation method. J Cell Biol. 1987;105:2589-2601.
43. Abe T, Sugano E, Saigo Y, Tamai M. Interleukin-1beta and barrier function of retinal pigment epithelial cells (ARPE-19): aberrant expression of junctional complex molecules. Invest Ophthalmol Vis Sci. 2003;44:4097-4104.
44. Redmond TM, Yu S, Lee E, et al. Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle. Nat Genet. 1998;20:344-351.
45. Mori M, Metzger D, Picaud S, et al. Retinal dystrophy resulting from ablation of RXR alpha in the mouse retinal pigment epithelium. Am J Pathol. 2004;164:701-710.
46. Chang CW, Ye L, Defoe DM, Caldwell RB. Serum inhibits tight junction formation in cultured pigment epithelial cells. Invest Ophthalmol Vis Sci. 1997;38:1082-1093.
47. Ryeom SW, Sparrow JR, Silverstein RL. CD36 participates in the phagocytosis of rod outer segments by retinal pigment epithelium. J Cell Sci. 1996;109(pt 2):387-395.
48. Finnemann SC, Bonilha VL, Marmorstein AD, Rodriguez-Boulan E. Phagocytosis of rod outer segments by retinal pigment epithelial cells requires alpha(v)beta5 integrin for binding but not for internalization. Proc Natl Acad Sci U S A. 1997;94:12932-12937.
49. Holtkamp GM, Kijlstra A, Peek R, de Vos AF. Retinal pigment epithelium-immune system interactions: cytokine production and cytokine-induced changes. Prog Retin Eye Res. 2001;20:29-48.
50. Anderson DH, Mullins RF, Hageman GS, Johnson LV. A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol. 2002;134:411-431.
51. Hageman GS, Luthert PJ, Victor Chong NH, Johnson LV, Anderson DH, Mullins RF. An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res. 2001;20:705-732.
52. Lund RD, Adamson P, Sauve Y, et al. Subretinal transplantation of genetically modified human cell lines attenuates loss of visual function in dystrophic rats. Proc Natl Acad Sci U S A. 2001;98:9942-9947.
53. Marshall J, Ansell PL. Membranous inclusions in the retinal pigment epithelium: phagosomes and myeloid bodies. J Anat. 1971;110:91-104.
54. Nandrot EF, Kim Y, Brodie SE, Huang X, Sheppard D, Finnemann SC. Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking αvβ5 integrin. J Exp Med. 2004;200:1539-1545.
55. Boyle D, Tien LF, Cooper NG, Shepherd V, McLaughlin BJ. A mannose receptor is involved in retinal phagocytosis. Invest Ophthalmol Vis Sci. 1991;32:1464-1470.
56. Uetama T, Ohno-Matsui K, Nakahama K, Morita I, Mochizuki M. Phenotypic change regulates monocyte chemoattractant protein-1 (MCP-1) gene expression in human retinal pigment epithelial cells. J Cell Physiol. 2003;197:77-85.
57. Rollins BJ. Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease. Mol Med Today. 1996;2:198-204.
58. Charo IF, Peters W. Chemokine receptor 2 (CCR2) in atherosclerosis, infectious diseases, and regulation of T-cell polarization. Microcirculation. 2003;10:259-264.
59. Ambati J, Anand A, Fernandez S, et al. An animal model of age-related macular degeneration in senescent ccl-2- or ccr-2-deficient mice. Nat Med. 2003;9:1390-1397.