Is spinal muscular atrophy a disease of the motor neurons only: Pathogenesis and therapeutic implications?

Cellular and Molecular Life Sciences

Volumn 73, Issue 5, 2016, Pages 1003-1020

  Simone, Chiara ^a   Ramirez, Agnese ^a   Bucchia, Monica ^a   Rinchetti, Paola ^a   Rideout, Hardy ^b   Papadimitriou, Dimitra ^b   Re, Diane B ^c   Corti, Stefania ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^c Columbia University ^*  (United States)

Author keywords

Central nervous system; Pathogenesis; Spinal muscular atrophy; Therapy

Indexed keywords

PARVOVIRUS VECTOR; SOMATOMEDIN C; SURVIVAL MOTOR NEURON PROTEIN 1; SURVIVAL MOTOR NEURON PROTEIN 2; VESICULAR GLUTAMATE TRANSPORTER 1;

ARTICLE; ASTROCYTE; ASTROCYTOSIS; BONE DISEASE; CELL LOSS; CELL SURVIVAL; CONGENITAL HEART MALFORMATION; CYTOKINE PRODUCTION; GASTROINTESTINAL DISEASE; HEART DEVELOPMENT; HUMAN; HYPOXIA; INTERNEURON; LIVER DISEASE; MICROGLIA; MOTONEURON; MUSCLE CELL; NERVE DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NEUROMUSCULAR SYNAPSE; NEUROPROTECTION; NONHUMAN; PANCREAS DISEASE; PATHOGENESIS; PHAGOCYTOSIS; SCHWANN CELL; SENSORY NERVE CELL; SPINAL MUSCULAR ATROPHY; ANIMAL; BONE; CARDIAC MUSCLE; COMPLICATION; GLIA; IMMUNE SYSTEM; LIVER; MUSCULAR ATROPHY, SPINAL; NERVE CELL; PANCREAS; PATHOLOGY;

ANIMALS; BONE AND BONES; HUMANS; IMMUNE SYSTEM; LIVER; MOTOR NEURONS; MUSCLE CELLS; MUSCULAR ATROPHY, SPINAL; MYOCARDIUM; NEUROGLIA; NEURONS; PANCREAS; SCHWANN CELLS;

EID: 84957430895     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-015-2106-9     Document Type: Article

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