Early heart failure in the SMNΔ7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery

Human Molecular Genetics

Volumn 19, Issue 20, 2010, Pages 3895-3905

  Bevan, Adam K ^a,b   Hutchinson, Kirk R ^a,c   Foust, Kevin D ^a   Braun, Lyndsey ^a   McGovern, Vicki L ^b   Schmelzer, Leah ^a   Ward, Jennifer G ^d   Petruska, Jeffrey C ^e   Lucchesi, Pamela A ^a   Burghes, Arthur H M ^b   Kaspar, Brian K ^a,b  

^a NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Specialty VETPATH   (United States)

^e University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SURVIVAL MOTOR NEURON PROTEIN;

ADENO ASSOCIATED VIRUS; ANATOMY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTONOMIC DYSFUNCTION; BRADYCARDIA; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAM; GENE TARGETING; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CONTRACTILITY; MOUSE; NONHUMAN; PERINATAL PERIOD; PHYSIOLOGY; PRIORITY JOURNAL; SPINAL MUSCULAR ATROPHY; SYMPTOM; TRANSGENE;

ANIMALS; BRADYCARDIA; CARDIOMYOPATHY, DILATED; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; GENE THERAPY; GENE TRANSFER TECHNIQUES; HEART FAILURE; MICE; MICE, TRANSGENIC; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; MYOCARDIAL CONTRACTION; NERVE TISSUE PROTEINS; SMN COMPLEX PROTEINS; SURVIVAL OF MOTOR NEURON 1 PROTEIN; VENTRICULAR FUNCTION, LEFT;

ADENO-ASSOCIATED VIRUS; ANIMALIA; MUS;

EID: 77957741150     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq300     Document Type: Article

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