Intramuscular scAAV9-SMN injection mediates widespread gene delivery to the spinal cord and decreases disease severity in SMA mice

Molecular Therapy

Volumn 21, Issue 2, 2013, Pages 282-290

  Benkhelifa Ziyyat, Sofia ^a   Besse, Aurore ^a   Roda, Marianne ^a   Duque, Sandra ^a   Astord, Stéphanie ^a   Carcenac, Romain ^a   Marais, Thibaut ^a   Barkats, Martine ^a  

^a Sorbonne Université   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; SURVIVAL MOTOR NEURON PROTEIN;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BRAIN CIRCULATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DISEASE SEVERITY; GASTROCNEMIUS MUSCLE; MOTOR NEURON DISEASE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SPINAL CORD DISEASE; SPINAL MUSCULAR ATROPHY; VIRAL GENE DELIVERY SYSTEM;

ADENO-ASSOCIATED VIRUS; ANIMALIA; MUS;

EID: 84873410199     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2012.261     Document Type: Article

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