KLF4 is a key determinant in the development and progression of cerebral cavernous malformations

EMBO Molecular Medicine

Volumn 8, Issue 1, 2016, Pages 6-24

  Cuttano, Roberto ^a   Rudini, Noemi ^a   Bravi, Luca ^a   Corada, Monica ^a   Giampietro, Costanza ^a,b   Papa, Eleanna ^a,c   Morini, Marco Francesco ^a,d   Maddaluno, Luigi ^a,e   Baeyens, Nicolas ^f   Adams, Ralf H ^g   Jain, Mukesh K ^h,i,j   Owens, Gary K ^k   Schwartz, Martin ^f   Lampugnani, Maria Grazia ^a,l   Dejana, Elisabetta ^a,b,m  

^a FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d UNIVERSITY OF BASEL   (Switzerland)

^e ETH ZURICH   (Switzerland)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF MÜNSTER   (Germany)

^h CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ Harrington Heart and Vascular Institute   (United States)

^j UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^k UNIVERSITY OF VIRGINIA   (United States)

^l MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^m UPPSALA UNIVERSITY   (Sweden)

more..

Author keywords

CCM; EndMT; Endothelial cells; KLF4; TGF BMP

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 6; KRUPPEL LIKE FACTOR 4; MITOGEN ACTIVATED PROTEIN KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE 5; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 3; MYOCYTE ENHANCER FACTOR 2; TRANSFORMING GROWTH FACTOR BETA; KRIT1 PROTEIN, MOUSE; KRUPPEL LIKE FACTOR; MICROTUBULE ASSOCIATED PROTEIN; ONCOPROTEIN; SMAD1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAVERNOUS HEMANGIOMA; CELL TRANSFORMATION; CONTROLLED STUDY; DISEASE COURSE; ENDOTHELIAL TO MESENCHYMAL TRANSITION; ENZYME ACTIVATION; IN VIVO STUDY; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; PROTEIN TARGETING; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN HEMANGIOMA; C57BL MOUSE; CELL PROLIFERATION; CYTOLOGY; DISEASE MODEL; ENDOTHELIUM CELL; GENETICS; HEK293 CELL LINE; HUMAN; KNOCKOUT MOUSE; METABOLISM; MUTATION; PATHOLOGY; RNA INTERFERENCE;

ANIMALS; BONE MORPHOGENETIC PROTEIN 6; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENDOTHELIAL CELLS; HEK293 CELLS; HEMANGIOMA, CAVERNOUS, CENTRAL NERVOUS SYSTEM; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 7; MUTATION; PROTO-ONCOGENE PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMAD1 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84956845911     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201505433     Document Type: Article

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