Signaling pathways and the cerebral cavernous malformations proteins: Lessons from structural biology

Cellular and Molecular Life Sciences

Volumn 71, Issue 10, 2014, Pages 1881-1892

  Fisher, Oriana S ^a   Boggon, Titus J ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE CANCER CENTER   (United States)

Author keywords

CCM complex signaling platform; Cerebral cavernous malformations; Integrin signaling; Kinases; Neurovasculature

Indexed keywords

BINDING PROTEIN; BRAIN PROTEIN; CELL ENZYME; CEREBRAL CAVERNOUS MALFORMATION 2 PROTEIN; CEREBRAL CAVERNOUS MALFORMATION 3 PROTEIN; CEREBRAL CAVERNOUS MALFORMATION PROTEIN; DELTA NOTCH PROTEIN; GERMINAL CENTER KINASE III; HEART OF GLASS RECEPTOR PROTEIN; ICAP1 PROTEIN; KRIT1 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NOTCH RECEPTOR; PAXILLIN; RAP1 PROTEIN; REACTIVE OXYGEN METABOLITE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; ROCK PROTEIN; SMAD PROTEIN; SMURF1 PROTEIN; STRIPAK PROTEIN; TUBULIN; UNCLASSIFIED DRUG;

CAVERNOUS HEMANGIOMA; CELL ADHESION; CELLULAR DISTRIBUTION; COMPLEX FORMATION; DISEASE ACTIVITY; EXOCYTOSIS; HUMAN; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NONHUMAN; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION;

MORUS (ANGIOSPERM);

CARRIER PROTEINS; CELL DEATH; EXOCYTOSIS; HEMANGIOMA, CAVERNOUS, CENTRAL NERVOUS SYSTEM; HUMANS; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; PAXILLIN; SIGNAL TRANSDUCTION; TUBULIN;

EID: 84900306632     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-013-1532-9     Document Type: Review

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