Endothelial krüppel-like factor 4 regulates angiogenesis and the notch signaling pathway

Journal of Biological Chemistry

Volumn 289, Issue 17, 2014, Pages 12016-12028

  Hale, Andrew T ^a   Tian, Hongmei ^a   Anih, Ejike ^a   Recio Iii, Fernando O ^a   Shatat, Mohammad A ^a,b   Johnson, Trent ^a   Liao, Xudong ^a   Ramirez Bergeron, Diana L ^a   Proweller, Aaron ^a   Ishikawa, Masakazu ^a   Hamik, Anne ^a,c  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Div Pulmon and Critical Care Med   (United States)

^c LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; ENDOTHELIAL CELLS;

ANGIOGENESIS; NOTCH SIGNALING PATHWAYS; THERAPEUTIC TARGETS; TUMOR ANGIOGENESIS; TUMOR GROWTH;

TUMORS;

ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; JAGGED1; KRUPPEL LIKE FACTOR 4; MEMBRANE PROTEIN; NOTCH LIGAND DLL1; NOTCH LIGAND DLL4; NOTCH RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; TRANSCRIPTION FACTOR HES 1; UNCLASSIFIED DRUG; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; ACTIN; KRUPPEL LIKE FACTOR; MOLECULAR MOTOR; MYOSIN; PRIMER DNA;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE; CELL METABOLISM; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENOS GENE; GENE CONTROL; GENE DOSAGE; GENE EXPRESSION; GENETIC TRANSFECTION; HIF 1 ALPHA GENE; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; MELANOMA CELL; MOLECULAR DYNAMICS; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPROUTING ANGIOGENESIS; TRANSCRIPTION REGULATION; TUMOR HYPOXIA; UMBILICAL VEIN ENDOTHELIAL CELL; VEGFA GENE; VEGFR1 GENE; VEGFR2 GENE; ANIMAL; ARABIDOPSIS; ATPASES; CHROMATIN IMMUNOPRECIPITATION; EXPERIMENTAL MELANOMA; GENE SILENCING; GENETICS; KINETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE; TUMOR CELL LINE; VASCULAR ENDOTHELIUM; VASCULARIZATION;

ACTIN; ARABIDOPSIS; ATPASES; KINETICS; MOLECULAR MOTORS; MYOSIN;

ANIMALS; BASE SEQUENCE; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; DNA PRIMERS; ENDOTHELIUM, VASCULAR; GENE KNOCKDOWN TECHNIQUES; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MELANOMA, EXPERIMENTAL; MICE; MICE, TRANSGENIC; NEOVASCULARIZATION, PATHOLOGIC; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 84899446193     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.530956     Document Type: Article

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