The Cerebral Cavernous Malformation Pathway Controls Cardiac Development via Regulation of Endocardial MEKK3 Signaling and KLF Expression

Developmental Cell

Volumn 32, Issue 2, 2015, Pages 168-180

  Zhou, Zinan ^a   Rawnsley, David R ^a   Goddard, Lauren M ^a   Pan, Wei ^a   Cao, Xing Jun ^a   Jakus, Zoltan ^a,g   Zheng, Hui ^a   Yang, Jisheng ^a   Arthur, J Simon C ^b   Whitehead, Kevin J ^c   Li, Dean ^c,d   Zhou, Bin ^e   Garcia, Benjamin A ^a   Zheng, Xiangjian ^a,f   Kahn, Mark L ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d SICHUAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^f CENTENARY INSTITUTE   (Australia)

^g SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECANASE 1; AGGRECANASE 2; CCM2 PROTEIN; KRIT1 PROTEIN; KRUPPEL LIKE FACTOR 2; KRUPPEL LIKE FACTOR 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 3; PDCD10 PROTEIN; PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; KRUPPEL LIKE FACTOR; MAP3K3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRANCHIAL ARCH; CEREBRAL CAVERNOUS MALFORMATION SIGNALING PATHWAY; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENDOCARDIUM; ENDOTHELIUM; ENZYME ACTIVITY; GENE; GENE DELETION; GESTATIONAL AGE; HAPLOINSUFFICIENCY; HEART DEVELOPMENT; HEART FAILURE; HEART MUSCLE; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; ENDOTHELIUM CELL; METABOLISM; TRANSGENIC MOUSE;

ANIMALS; CARRIER PROTEINS; ENDOCARDIUM; ENDOTHELIAL CELLS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MAP KINASE KINASE KINASE 3; MAP KINASE SIGNALING SYSTEM; MICE; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES;

EID: 84921523373     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2014.12.009     Document Type: Article

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