메뉴 건너뛰기




Volumn 12, Issue 5, 2005, Pages 456-463

RNAi technology and lentiviral delivery as a powerful tool to suppress Tpr-Met-mediated tumorigenesis

Author keywords

Gastric cancer; Lentiviral vector; Novel cancer therapies; ShRNA; Tpr Met

Indexed keywords

LENTIVIRUS VECTOR; SCATTER FACTOR RECEPTOR; SMALL INTERFERING RNA;

EID: 20944448996     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700815     Document Type: Article
Times cited : (34)

References (43)
  • 1
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 1998;391:806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3
  • 2
    • 0032443021 scopus 로고    scopus 로고
    • Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway
    • Kennerdell JR, Carthew RW. Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway. Cell. 1998;905:1017-1026.
    • (1998) Cell , vol.905 , pp. 1017-1026
    • Kennerdell, J.R.1    Carthew, R.W.2
  • 3
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science. 2002;296:550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 4
    • 0036256430 scopus 로고    scopus 로고
    • Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
    • Lee NS, Dohjima T, Bauer G, et al. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol. 2002;20:500-505.
    • (2002) Nat Biotechnol , vol.20 , pp. 500-505
    • Lee, N.S.1    Dohjima, T.2    Bauer, G.3
  • 5
    • 0042319070 scopus 로고    scopus 로고
    • Development and application of siRNA expression vector
    • Miyagishi M, Taira K. Development and application of siRNA expression vector. Nucleic Acids Res. 2002;2(Suppl):113-114.
    • (2002) Nucleic Acids Res , vol.2 , Issue.SUPPL. , pp. 113-114
    • Miyagishi, M.1    Taira, K.2
  • 6
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    • Paddison PJ, Caudy AA, Bernstein E, et al. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 2002;16:948-958.
    • (2002) Genes Dev , vol.16 , pp. 948-958
    • Paddison, P.J.1    Caudy, A.A.2    Bernstein, E.3
  • 7
    • 0037440160 scopus 로고    scopus 로고
    • Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells
    • Kawasaki H, Taira K. Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells. Nucleic Acids Res. 2003;31:700-707.
    • (2003) Nucleic Acids Res , vol.31 , pp. 700-707
    • Kawasaki, H.1    Taira, K.2
  • 8
    • 0036726313 scopus 로고    scopus 로고
    • Stable suppression of tumorigenicity by virus-mediated RNA interference
    • Brummelkamp TR, Bernards R, Agami R. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell. 2002;2:243-247.
    • (2002) Cancer Cell , vol.2 , pp. 243-247
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 9
    • 0037069417 scopus 로고    scopus 로고
    • Retroviral delivery of small interfering RNA into primary cells
    • Barton GM, Medzhitov R. Retroviral delivery of small interfering RNA into primary cells. Proc Natl Acad Sci USA. 2002;99:14943-14945.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14943-14945
    • Barton, G.M.1    Medzhitov, R.2
  • 10
    • 0037422583 scopus 로고    scopus 로고
    • Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
    • Qin XF, An DS, Chen IS, et al. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc Natl Acad Sci USA. 2003;100:183-188.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 183-188
    • Qin, X.F.1    An, D.S.2    Chen, I.S.3
  • 11
    • 0037370498 scopus 로고    scopus 로고
    • A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
    • Rubinson DA, Dillon CP, Kwiatkowski AV, et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet. 2003;33:401-406.
    • (2003) Nat Genet , vol.33 , pp. 401-406
    • Rubinson, D.A.1    Dillon, C.P.2    Kwiatkowski, A.V.3
  • 12
    • 10744219596 scopus 로고    scopus 로고
    • Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector
    • van de Wetering M, Oving I, Muncan V, et al. Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector. EMBO Rep. 2003;4:609-615.
    • (2003) EMBO Rep , vol.4 , pp. 609-615
    • Van De Wetering, M.1    Oving, I.2    Muncan, V.3
  • 13
    • 0642303887 scopus 로고    scopus 로고
    • Inducible shRNA expression for application in a prostate cancer mouse model
    • Czauderna F, Santel A, Hinz M, et al. Inducible shRNA expression for application in a prostate cancer mouse model. Nucleic Acids Res. 2003;31:e127.
    • (2003) Nucleic Acids Res , vol.31
    • Czauderna, F.1    Santel, A.2    Hinz, M.3
  • 14
    • 0042941765 scopus 로고    scopus 로고
    • Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro
    • Chen Y, Stamatoyannopoulos G, Song CZ. Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro. Cancer Res. 2003;63:4801-4804.
    • (2003) Cancer Res , vol.63 , pp. 4801-4804
    • Chen, Y.1    Stamatoyannopoulos, G.2    Song, C.Z.3
  • 16
    • 0023011874 scopus 로고
    • Activation of the met oncogene in the human MNNG-HOS cell line involves a chromosomal rearrangement
    • Tempest PR, Reeves BR, Spurr NK, et al. Activation of the met oncogene in the human MNNG-HOS cell line involves a chromosomal rearrangement. Carcinogenesis. 1986;7: 2051-2057.
    • (1986) Carcinogenesis , vol.7 , pp. 2051-2057
    • Tempest, P.R.1    Reeves, B.R.2    Spurr, N.K.3
  • 17
    • 0027369598 scopus 로고
    • Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase
    • Rodrigues GA, Park M. Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase. Mol Cell Biol. 1993;13:6711-6722.
    • (1993) Mol Cell Biol , vol.13 , pp. 6711-6722
    • Rodrigues, G.A.1    Park, M.2
  • 18
    • 0024487135 scopus 로고
    • Induction of gastric cancer in monkeys by N-methyl-N-nitro-N- nitrosoguanidine (MNNG)
    • Sharashidze LK, Beniashvili DSh, Sherenesheva NI, et al. Induction of gastric cancer in monkeys by N-methyl-N-nitro-N-nitrosoguanidine (MNNG). Neoplasma. 1989;36: 129-133.
    • (1989) Neoplasma , vol.36 , pp. 129-133
    • Sharashidze, L.K.1    Beniashvili, D.Sh.2    Sherenesheva, N.I.3
  • 19
    • 0025828180 scopus 로고
    • The TPR-MET oncogenic rearrangement is present and expressed in human gastric carcinoma and precursor lesions
    • Soman NR, Correa P, Ruiz BA, et al. The TPR-MET oncogenic rearrangement is present and expressed in human gastric carcinoma and precursor lesions. Proc Natl Acad Sci USA. 1991;88:4892-4896.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4892-4896
    • Soman, N.R.1    Correa, P.2    Ruiz, B.A.3
  • 20
    • 0342314433 scopus 로고    scopus 로고
    • Frequency of TPR-MET rearrangement in patients with gastric carcinoma and in first-degree relatives
    • Yu J, Miehlke S, Ebert MP, et al. Frequency of TPR-MET rearrangement in patients with gastric carcinoma and in first-degree relatives. Cancer. 2000;88:1801-1806.
    • (2000) Cancer , vol.88 , pp. 1801-1806
    • Yu, J.1    Miehlke, S.2    Ebert, M.P.3
  • 21
    • 0033946580 scopus 로고    scopus 로고
    • Formation of N-(nitrosomethyl)urea in stomachs of experimental pigs and human volunteers given fish sauce in vivo
    • Deng D, Xin H. Formation of N-(nitrosomethyl)urea in stomachs of experimental pigs and human volunteers given fish sauce in vivo. J Agric Food Chem. 2000;48:2495-2498.
    • (2000) J Agric Food Chem , vol.48 , pp. 2495-2498
    • Deng, D.1    Xin, H.2
  • 22
    • 0034866499 scopus 로고    scopus 로고
    • Formation of N-nitroso-N-methylurea in various samples of smoked/dried fish, fish sauce, seafoods, and ethnic fermented/pickled vegetables following incubation with nitrite under acidic conditions
    • Sen NP, Seaman SW, Badoo PA, et al. Formation of N-nitroso-N-methylurea in various samples of smoked/dried fish, fish sauce, seafoods, and ethnic fermented/pickled vegetables following incubation with nitrite under acidic conditions. J Agric Food Chem. 2001;49:2096-2103.
    • (2001) J Agric Food Chem , vol.49 , pp. 2096-2103
    • Sen, N.P.1    Seaman, S.W.2    Badoo, P.A.3
  • 23
    • 0036221263 scopus 로고    scopus 로고
    • Dysregulation of Met receptor tyrosine kinase activity in invasive tumors
    • Danilkovitch-Miagkova A, Zbar B. Dysregulation of Met receptor tyrosine kinase activity in invasive tumors. J Clin Invest. 2002;109:863-867.
    • (2002) J Clin Invest , vol.109 , pp. 863-867
    • Danilkovitch-Miagkova, A.1    Zbar, B.2
  • 24
    • 0034641890 scopus 로고    scopus 로고
    • A novel germ line juxtamembrane Met mutation in human gastric cancer
    • Lee JH, Han SU, Cho H, et al. A novel germ line juxtamembrane Met mutation in human gastric cancer. Oncogene. 2000;19:4947-4953.
    • (2000) Oncogene , vol.19 , pp. 4947-4953
    • Lee, J.H.1    Han, S.U.2    Cho, H.3
  • 25
    • 0141988690 scopus 로고    scopus 로고
    • c-MET mutational analysis in small cell lung cancer: Novel juxtamembrane domain mutations regulating cytoskeletal functions
    • Ma PC, Kijima T, Maulik G. c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions. Cancer Res. 2003;63:6272-6281.
    • (2003) Cancer Res , vol.63 , pp. 6272-6281
    • Ma, P.C.1    Kijima, T.2    Maulik, G.3
  • 26
    • 0242694513 scopus 로고    scopus 로고
    • Suppression of met expression: A possible cancer treatment
    • Shinomiya N, Vande Woude GF. Suppression of met expression: a possible cancer treatment. Clin Cancer Res. 2003;9:5085-5090.
    • (2003) Clin Cancer Res , vol.9 , pp. 5085-5090
    • Shinomiya, N.1    Vande Woude, G.F.2
  • 27
    • 0038724909 scopus 로고    scopus 로고
    • c-Met: Structure, functions and potential for therapeutic inhibition
    • Ma PC, Maulik G, Christensen J, et al. c-Met: structure, functions and potential for therapeutic inhibition. Cancer Metast Rev. 2003;22:309-325.
    • (2003) Cancer Metast Rev , vol.22 , pp. 309-325
    • Ma, P.C.1    Maulik, G.2    Christensen, J.3
  • 28
    • 0037173756 scopus 로고    scopus 로고
    • K252a inhibits the oncogenic properties of Met, the HGF receptor
    • Morotti A, Mila S, Accornero P, et al. K252a inhibits the oncogenic properties of Met, the HGF receptor. Oncogene. 2002;21:4885-4893.
    • (2002) Oncogene , vol.21 , pp. 4885-4893
    • Morotti, A.1    Mila, S.2    Accornero, P.3
  • 29
    • 0141481285 scopus 로고    scopus 로고
    • A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase
    • Sattler M, Pride YB, Ma P, et al. A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase. Cancer Res. 2003;63:5462-5469.
    • (2003) Cancer Res , vol.63 , pp. 5462-5469
    • Sattler, M.1    Pride, Y.B.2    Ma, P.3
  • 30
    • 10744228765 scopus 로고    scopus 로고
    • A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo
    • Christensen JG, Schreck R, Burrows J, et al. A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo. Cancer Res. 2003;63: 7345-7355.
    • (2003) Cancer Res , vol.63 , pp. 7345-7355
    • Christensen, J.G.1    Schreck, R.2    Burrows, J.3
  • 31
    • 0034595002 scopus 로고    scopus 로고
    • Two mutations affecting conserved residues in the Met receptor operate via different mechanisms
    • Maritano D, Accornero P, Bonifaci N, et al. Two mutations affecting conserved residues in the Met receptor operate via different mechanisms. Oncogene. 2000; 19:1354-1361.
    • (2000) Oncogene , vol.19 , pp. 1354-1361
    • Maritano, D.1    Accornero, P.2    Bonifaci, N.3
  • 32
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 2001;411:494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3
  • 33
    • 0034040751 scopus 로고    scopus 로고
    • Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
    • Follenzi A, Ailles LE, Bakovic S, et al. Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences. Nat Genet. 2000;25: 217-222.
    • (2000) Nat Genet , vol.25 , pp. 217-222
    • Follenzi, A.1    Ailles, L.E.2    Bakovic, S.3
  • 34
    • 0025886454 scopus 로고
    • Evidence for the identity of human scatter factor and human hepatocyte growth factor
    • Weidner KM, Arakaki N, Hartmann G, et al. Evidence for the identity of human scatter factor and human hepatocyte growth factor. Proc Natl Acad Sci USA. 1991;88: 7001-7005.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7001-7005
    • Weidner, K.M.1    Arakaki, N.2    Hartmann, G.3
  • 35
    • 0141528828 scopus 로고    scopus 로고
    • Chronic myeloid leukemia - Advances in biology and new approaches to treatment
    • Goldman JM, Melo JV. Chronic myeloid leukemia - advances in biology and new approaches to treatment. N Engl J Med. 2003;349:1451-1464.
    • (2003) N Engl J Med , vol.349 , pp. 1451-1464
    • Goldman, J.M.1    Melo, J.V.2
  • 36
    • 0037225829 scopus 로고    scopus 로고
    • Imatinib mesylate: In the treatment of gastrointestinal stromal tumours
    • Croom KF, Perry CM. Imatinib mesylate: in the treatment of gastrointestinal stromal tumours. Drugs. 2003;63: 513-522.
    • (2003) Drugs , vol.63 , pp. 513-522
    • Croom, K.F.1    Perry, C.M.2
  • 37
    • 0032211172 scopus 로고    scopus 로고
    • The presence of typical and atypical BCR-ABL fusion genes in leukocytes of normal individuals: Biologic significance and implications for the assessment of minimal residual disease
    • Bose S, Deininger M, Gora-Tybor J, et al. The presence of typical and atypical BCR-ABL fusion genes in leukocytes of normal individuals: biologic significance and implications for the assessment of minimal residual disease. Blood. 1998;92:3362-3367.
    • (1998) Blood , vol.92 , pp. 3362-3367
    • Bose, S.1    Deininger, M.2    Gora-Tybor, J.3
  • 38
    • 0041335551 scopus 로고    scopus 로고
    • Silencing of H-ras gene expression by retrovirus-mediated siRNA decreases transformation efficiency and tumor growth in a model of human ovarian cancer
    • Yang G, Thompson JA, Fang B, et al. Silencing of H-ras gene expression by retrovirus-mediated siRNA decreases transformation efficiency and tumor growth in a model of human ovarian cancer. Oncogene. 2003;22:5694-5701.
    • (2003) Oncogene , vol.22 , pp. 5694-5701
    • Yang, G.1    Thompson, J.A.2    Fang, B.3
  • 39
    • 0037441756 scopus 로고    scopus 로고
    • Specific inhibition of bcr-abl gene expression by small interfering RNA
    • Scherr M, Battmer K, Winkler T, et al. Specific inhibition of bcr-abl gene expression by small interfering RNA. Blood. 2003;101:1566-1569.
    • (2003) Blood , vol.101 , pp. 1566-1569
    • Scherr, M.1    Battmer, K.2    Winkler, T.3
  • 40
    • 0141816881 scopus 로고    scopus 로고
    • Suppression of BRAF(V599E) in human melanoma abrogates transformation
    • Hingorani SR, Jacobetz MA, Robertson GP, et al. Suppression of BRAF(V599E) in human melanoma abrogates transformation. Cancer Res. 2003;63:5198-5202.
    • (2003) Cancer Res , vol.63 , pp. 5198-5202
    • Hingorani, S.R.1    Jacobetz, M.A.2    Robertson, G.P.3
  • 41
    • 0038756442 scopus 로고    scopus 로고
    • Use of RNA interference to target cyclin E-overexpressing hepatocellular carcinoma
    • Li K, Lin SY, Brunicardi FC, Seu P. Use of RNA interference to target cyclin E-overexpressing hepatocellular carcinoma. Cancer Res. 2003;63:3593-3597.
    • (2003) Cancer Res , vol.63 , pp. 3593-3597
    • Li, K.1    Lin, S.Y.2    Brunicardi, F.C.3    Seu, P.4
  • 42
    • 0042173218 scopus 로고    scopus 로고
    • SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth
    • Filleur S, Courtin A, Ait-Si-Ali S, et al. SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth. Cancer Res. 2003;63:2319-2322.
    • (2003) Cancer Res , vol.63 , pp. 2319-2322
    • Filleur, S.1    Courtin, A.2    Ait-Si-Ali, S.3
  • 43
    • 0037025173 scopus 로고    scopus 로고
    • Cancer, addiction to oncogenes - The Achilles heal of cancer
    • Weinstein IB. Cancer, addiction to oncogenes - the Achilles heal of cancer. Science. 2002;297:63-64.
    • (2002) Science , vol.297 , pp. 63-64
    • Weinstein, I.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.