-
1
-
-
43249130187
-
Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cellsuppressive activity
-
Movahedi, K. et al. Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cellsuppressive activity. Blood 111, 4233-4244 (2008).
-
(2008)
Blood
, vol.111
, pp. 4233-4244
-
-
Movahedi, K.1
-
2
-
-
80053613350
-
Myeloid derived suppressor cells in transplantation
-
Lees, J. R., Azimzadeh, A. M., Bromberg, J. S. Myeloid derived suppressor cells in transplantation. Curr Opin Immunol 23, 692-697 (2011).
-
(2011)
Curr Opin Immunol
, vol.23
, pp. 692-697
-
-
Lees, J.R.1
Azimzadeh, A.M.2
Bromberg, J.S.3
-
3
-
-
84907259222
-
The roles of myeloid-derived suppressor cells in transplantation
-
Wu, T., Zhao, Y., Zhao, Y. The roles of myeloid-derived suppressor cells in transplantation. Expert review of clinical immunology 10, 1385-1394 (2014).
-
(2014)
Expert Review of Clinical Immunology
, vol.10
, pp. 1385-1394
-
-
Wu, T.1
Zhao, Y.2
Zhao, Y.3
-
4
-
-
0035164478
-
Increased production of immature myeloid cells in cancer patients: A mechanism of immunosuppression in cancer
-
Almand, B. et al. Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J Immunol 166, 678-689 (2001).
-
(2001)
J Immunol
, vol.166
, pp. 678-689
-
-
Almand, B.1
-
5
-
-
70350133511
-
IL4Ralpha + myeloid-derived suppressor cell expansion in cancer patients
-
Mandruzzato, S. et al. IL4Ralpha + myeloid-derived suppressor cell expansion in cancer patients. J Immunol 182, 6562-6568 (2009).
-
(2009)
J Immunol
, vol.182
, pp. 6562-6568
-
-
Mandruzzato, S.1
-
6
-
-
54049134747
-
Subsets of myeloid-derived suppressor cells in tumor-bearing mice
-
Youn, J. I., Nagaraj, S., Collazo, M., Gabrilovich, D. I. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol 181, 5791-5802 (2008).
-
(2008)
J Immunol
, vol.181
, pp. 5791-5802
-
-
Youn, J.I.1
Nagaraj, S.2
Collazo, M.3
Gabrilovich, D.I.4
-
7
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich, D. I., Nagaraj, S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 9, 162-174 (2009).
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
8
-
-
34447118098
-
Altered recognition of antigen is a mechanism of CD8 + T cell tolerance in cancer
-
Nagaraj, S. et al. Altered recognition of antigen is a mechanism of CD8 + T cell tolerance in cancer. Nature medicine 13, 828-835 (2007).
-
(2007)
Nature Medicine
, vol.13
, pp. 828-835
-
-
Nagaraj, S.1
-
9
-
-
69149103835
-
Endotoxin-induced myeloid-derived suppressor cells inhibit alloimmune responses via heme oxygenase-1
-
De Wilde, V. et al. Endotoxin-induced myeloid-derived suppressor cells inhibit alloimmune responses via heme oxygenase-1. American Journal of Transplantation 9, 2034-2047 (2009).
-
(2009)
American Journal of Transplantation
, vol.9
, pp. 2034-2047
-
-
De Wilde, V.1
-
10
-
-
81555228400
-
Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells
-
Obermajer, N., Muthuswamy, R., Lesnock, J., Edwards, R. P., Kalinski, P. Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells. Blood 118, 5498-5505 (2011).
-
(2011)
Blood
, vol.118
, pp. 5498-5505
-
-
Obermajer, N.1
Muthuswamy, R.2
Lesnock, J.3
Edwards, R.P.4
Kalinski, P.5
-
11
-
-
59849126377
-
Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1
-
Li, H., Han, Y., Guo, Q., Zhang, M., Cao, X. Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1. J Immunol 182, 240-249 (2009).
-
(2009)
J Immunol
, vol.182
, pp. 240-249
-
-
Li, H.1
Han, Y.2
Guo, Q.3
Zhang, M.4
Cao, X.5
-
12
-
-
80052671582
-
Physiologic control of IDO competence in splenic dendritic cells
-
Baban, B. et al. Physiologic control of IDO competence in splenic dendritic cells. J Immunol 187, 2329-2335 (2011).
-
(2011)
J Immunol
, vol.187
, pp. 2329-2335
-
-
Baban, B.1
-
13
-
-
78650756969
-
Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function
-
Condamine, T., Gabrilovich, D. I. Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function. Trends Immunol 32, 19-25 (2011).
-
(2011)
Trends Immunol
, vol.32
, pp. 19-25
-
-
Condamine, T.1
Gabrilovich, D.I.2
-
14
-
-
84868544881
-
Smad3-deficient CD11b(+ )Gr1(+ ) myeloid-derived suppressor cells prevent allograft rejection via the nitric oxide pathway
-
Wu, T. et al. Smad3-deficient CD11b(+ )Gr1(+ ) myeloid-derived suppressor cells prevent allograft rejection via the nitric oxide pathway. J Immunol 189, 4989-5000 (2012).
-
(2012)
J Immunol
, vol.189
, pp. 4989-5000
-
-
Wu, T.1
-
15
-
-
84906246466
-
A systematic review of conversion from calcineurin inhibitor to mammalian target of rapamycin inhibitors for maintenance immunosuppression in kidney transplant recipients American journal of transplantation
-
Lim, W. H. et al. A systematic review of conversion from calcineurin inhibitor to mammalian target of rapamycin inhibitors for maintenance immunosuppression in kidney transplant recipients. American journal of transplantation: official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 14, 2106-2119 (2014).
-
(2014)
Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
, vol.14
, pp. 2106-2119
-
-
Lim, W.H.1
-
16
-
-
84904814066
-
Targeting the phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway: An emerging treatment strategy for squamous cell lung carcinoma
-
Beck, J. T., Ismail, A., Tolomeo, C. Targeting the phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway: an emerging treatment strategy for squamous cell lung carcinoma. Cancer treatment reviews 40, 980-989 (2014).
-
(2014)
Cancer Treatment Reviews
, vol.40
, pp. 980-989
-
-
Beck, J.T.1
Ismail, A.2
Tolomeo, C.3
-
17
-
-
84907060513
-
Combined SFK/mTOR inhibition prevents rapamycin-induced feedback activation of AKT and elicits efficient tumor regression
-
Yori, J. L. et al. Combined SFK/mTOR inhibition prevents rapamycin-induced feedback activation of AKT and elicits efficient tumor regression. Cancer research 74, 4762-4771 (2014).
-
(2014)
Cancer Research
, vol.74
, pp. 4762-4771
-
-
Yori, J.L.1
-
18
-
-
84868212708
-
Phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway inhibition: A breakthrough in the management of luminal (ER +/HER2-) breast cancers
-
Zardavas, D., Fumagalli, D., Loi, S. Phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway inhibition: a breakthrough in the management of luminal (ER +/HER2-) breast cancers? Current opinion in oncology 24, 623-634 (2012).
-
(2012)
Current Opinion in Oncology
, vol.24
, pp. 623-634
-
-
Zardavas, D.1
Fumagalli, D.2
Loi, S.3
-
19
-
-
84864531704
-
Immunosuppressive drugs on inducing Ag-specific CD4(+ )CD25(+ )Foxp3(+ ) Treg cells during immune response in vivo
-
Wu, T. et al. Immunosuppressive drugs on inducing Ag-specific CD4(+ )CD25(+ )Foxp3(+ ) Treg cells during immune response in vivo. Transplant immunology 27, 30-38 (2012).
-
(2012)
Transplant Immunology
, vol.27
, pp. 30-38
-
-
Wu, T.1
-
20
-
-
84865301337
-
MTOR, metabolism, and the regulation of T-cell differentiation and function
-
Waickman, A. T., Powell, J. D. mTOR, metabolism, and the regulation of T-cell differentiation and function. Immunological reviews 249, 43-58 (2012).
-
(2012)
Immunological Reviews
, vol.249
, pp. 43-58
-
-
Waickman, A.T.1
Powell, J.D.2
-
21
-
-
33847218321
-
The effect of immunosuppressive drug rapamycin on regulatory CD4 + CD25 + Foxp3 + T cells in mice
-
Qu, Y. et al. The effect of immunosuppressive drug rapamycin on regulatory CD4 + CD25 + Foxp3 + T cells in mice. Transplant immunology 17, 153-161 (2007).
-
(2007)
Transplant Immunology
, vol.17
, pp. 153-161
-
-
Qu, Y.1
-
22
-
-
72449147738
-
The multifunctional role of mTOR in innate immunity: Implications for transplant immunity American journal of transplantation
-
Saemann, M. D., Haidinger, M., Hecking, M., Horl, W. H., Weichhart, T. The multifunctional role of mTOR in innate immunity: implications for transplant immunity. American journal of transplantation: official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 9, 2655-2661 (2009).
-
(2009)
Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
, vol.9
, pp. 2655-2661
-
-
Saemann, M.D.1
Haidinger, M.2
Hecking, M.3
Horl, W.H.4
Weichhart, T.5
-
23
-
-
77958126087
-
A versatile role of mammalian target of rapamycin in human dendritic cell function and differentiation
-
Haidinger, M. et al. A versatile role of mammalian target of rapamycin in human dendritic cell function and differentiation. J Immunol 185, 3919-3931 (2010).
-
(2010)
J Immunol
, vol.185
, pp. 3919-3931
-
-
Haidinger, M.1
-
24
-
-
54949109311
-
The TSC-mTOR signaling pathway regulates the innate inflammatory response
-
Weichhart, T. et al. The TSC-mTOR signaling pathway regulates the innate inflammatory response. Immunity 29, 565-577 (2008).
-
(2008)
Immunity
, vol.29
, pp. 565-577
-
-
Weichhart, T.1
-
25
-
-
84907363576
-
TSC1 controls macrophage polarization to prevent inflammatory disease
-
Zhu, L. et al. TSC1 controls macrophage polarization to prevent inflammatory disease. Nature communications 5, 4696 (2014).
-
(2014)
Nature Communications
, vol.5
, pp. 4696
-
-
Zhu, L.1
-
26
-
-
77951258918
-
Myeloid-derived suppressor cell heterogeneity and subset definition
-
Peranzoni, E. et al. Myeloid-derived suppressor cell heterogeneity and subset definition. Curr Opin Immunol 22, 238-244 (2010).
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 238-244
-
-
Peranzoni, E.1
-
27
-
-
78650465760
-
Rapamycin inhibits lipopolysaccharide induction of granulocyte-colony stimulating factor and inducible nitric oxide synthase expression in macrophages by reducing the levels of octamer-binding factor-2
-
Chou, Y. Y., Gao, J. I., Chang, S. F., Chang, P. Y., Lu, S. C. Rapamycin inhibits lipopolysaccharide induction of granulocyte-colony stimulating factor and inducible nitric oxide synthase expression in macrophages by reducing the levels of octamer-binding factor-2. FEBS J 278, 85-96 (2011).
-
(2011)
FEBS J
, vol.278
, pp. 85-96
-
-
Chou, Y.Y.1
Gao, J.I.2
Chang, S.F.3
Chang, P.Y.4
Lu, S.C.5
-
28
-
-
33846529557
-
PSGL-1 and mTOR regulate translation of ROCK-1 and physiological functions of macrophages
-
Fox, R. et al. PSGL-1 and mTOR regulate translation of ROCK-1 and physiological functions of macrophages. EMBO J 26, 505-515 (2007).
-
(2007)
EMBO J
, vol.26
, pp. 505-515
-
-
Fox, R.1
-
29
-
-
0037301527
-
Prolongation of allogeneic skin graft survival by injection of anti-Ly49A monoclonal antibody YE1/48
-
Yang, T. Y., Sun, Y., Langnas, A. N., Zhao, Y. Prolongation of allogeneic skin graft survival by injection of anti-Ly49A monoclonal antibody YE1/48. Clin Immunol 106, 148-154 (2003).
-
(2003)
Clin Immunol
, vol.106
, pp. 148-154
-
-
Yang, T.Y.1
Sun, Y.2
Langnas, A.N.3
Zhao, Y.4
-
30
-
-
33748471980
-
MSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s
-
Frias, M. A. et al. mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s. Current biology: CB 16, 1865-1870 (2006).
-
(2006)
Current Biology: CB
, vol.16
, pp. 1865-1870
-
-
Frias, M.A.1
-
31
-
-
33749076673
-
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
-
Jacinto, E. et al. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 127, 125-137 (2006).
-
(2006)
Cell
, vol.127
, pp. 125-137
-
-
Jacinto, E.1
-
32
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassov, D. D. et al. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol Cell 22, 159-168 (2006).
-
(2006)
Mol Cell
, vol.22
, pp. 159-168
-
-
Sarbassov, D.D.1
-
33
-
-
84885101700
-
Disruption of TSC1/2 signaling complex reveals a checkpoint governing thymic CD4 + CD25 + Foxp3 + regulatory T-cell development in mice
-
Chen, H. et al. Disruption of TSC1/2 signaling complex reveals a checkpoint governing thymic CD4 + CD25 + Foxp3 + regulatory T-cell development in mice. FASEB J 27, 3979-3990 (2013).
-
(2013)
FASEB J
, vol.27
, pp. 3979-3990
-
-
Chen, H.1
-
34
-
-
0037080021
-
Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism
-
Mazzoni, A. et al. Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism. J Immunol 168, 689-695 (2002).
-
(2002)
J Immunol
, vol.168
, pp. 689-695
-
-
Mazzoni, A.1
-
35
-
-
37349100945
-
Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1 + CD11b + myeloid cells that promote metastasis
-
Yang, L. et al. Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1 + CD11b + myeloid cells that promote metastasis. Cancer Cell 13, 23-35 (2008).
-
(2008)
Cancer Cell
, vol.13
, pp. 23-35
-
-
Yang, L.1
-
36
-
-
0024528921
-
A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation
-
Rees, D. D., Palmer, R. M., Hodson, H. F., Moncada, S. A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation. Br J Pharmacol 96, 418-424 (1989).
-
(1989)
Br J Pharmacol
, vol.96
, pp. 418-424
-
-
Rees, D.D.1
Palmer, R.M.2
Hodson, H.F.3
Moncada, S.4
-
37
-
-
84905757105
-
Metformin-mode of action and clinical implications for diabetes and cancer
-
Pernicova, I., Korbonits, M. Metformin-mode of action and clinical implications for diabetes and cancer. Nat Rev Endocrinol 10, 143-156 (2014).
-
(2014)
Nat Rev Endocrinol
, vol.10
, pp. 143-156
-
-
Pernicova, I.1
Korbonits, M.2
-
38
-
-
84920025605
-
Metformin in patients with type 2 diabetes and kidney disease: A systematic review
-
Inzucchi, S. E., Lipska, K. J., Mayo, H., Bailey, C. J., McGuire, D. K. Metformin in patients with type 2 diabetes and kidney disease: a systematic review. JAMA 312, 2668-2675 (2014).
-
(2014)
JAMA
, vol.312
, pp. 2668-2675
-
-
Inzucchi, S.E.1
Lipska, K.J.2
Mayo, H.3
Bailey, C.J.4
McGuire, D.K.5
-
39
-
-
49249130346
-
Metabolic actions of metformin in the heart can occur by AMPK-independent mechanisms
-
Saeedi, R. et al. Metabolic actions of metformin in the heart can occur by AMPK-independent mechanisms. Am J Physiol Heart Circ Physiol 294, H2497-2506 (2008).
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
, pp. H2497-2506
-
-
Saeedi, R.1
-
40
-
-
83355163333
-
Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models
-
Cheong, J. H. et al. Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models. Mol Cancer Ther 10, 2350-2362 (2011).
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 2350-2362
-
-
Cheong, J.H.1
-
41
-
-
84884211823
-
Targeting metabolism for cancer treatment and prevention: Metformin, an old drug with multi-faceted effects
-
Pierotti, M. A. et al. Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects. Oncogene 32, 1475-1487 (2013).
-
(2013)
Oncogene
, vol.32
, pp. 1475-1487
-
-
Pierotti, M.A.1
-
42
-
-
84904686912
-
Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells
-
Janzer, A. et al. Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells. Proc Natl Acad Sci USA 111, 10574-10579 (2014).
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 10574-10579
-
-
Janzer, A.1
-
43
-
-
84865130666
-
The mTOR-inhibitor rapamycin mediates proteinuria in nephrotoxic serum nephritis by activating the innate immune response American journal of physiology
-
Kirsch, A. H. et al. The mTOR-inhibitor rapamycin mediates proteinuria in nephrotoxic serum nephritis by activating the innate immune response. American journal of physiology. Renal physiology 303, F569-575 (2012).
-
(2012)
Renal Physiology
, vol.303
, pp. F569-575
-
-
Kirsch, A.H.1
-
44
-
-
79955973785
-
Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells
-
Weichhart, T. et al. Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells. Blood 117, 4273-4283 (2011).
-
(2011)
Blood
, vol.117
, pp. 4273-4283
-
-
Weichhart, T.1
-
46
-
-
50949120674
-
Myeloid-derived suppressor cells accumulate in kidney allograft tolerance and specifically suppress effector T cell expansion
-
Dugast, A. S. et al. Myeloid-derived suppressor cells accumulate in kidney allograft tolerance and specifically suppress effector T cell expansion. J Immunol 180, 7898-7906 (2008).
-
(2008)
J Immunol
, vol.180
, pp. 7898-7906
-
-
Dugast, A.S.1
-
47
-
-
55949116639
-
Human inhibitory receptor immunoglobulin-like transcript 2 amplifies CD11b + Gr1 + myeloid-derived suppressor cells that promote long-term survival of allografts
-
Zhang, W., Liang, S., Wu, J., Horuzsko, A. Human inhibitory receptor immunoglobulin-like transcript 2 amplifies CD11b + Gr1 + myeloid-derived suppressor cells that promote long-term survival of allografts. Transplantation 86, 1125-1134 (2008).
-
(2008)
Transplantation
, vol.86
, pp. 1125-1134
-
-
Zhang, W.1
Liang, S.2
Wu, J.3
Horuzsko, A.4
-
48
-
-
84862908818
-
AMPK and mTOR in cellular energy homeostasis and drug targets
-
Inoki, K., Kim, J., Guan, K. L. AMPK and mTOR in cellular energy homeostasis and drug targets. Annual review of pharmacology and toxicology 52, 381-400 (2012).
-
(2012)
Annual Review of Pharmacology and Toxicology
, vol.52
, pp. 381-400
-
-
Inoki, K.1
Kim, J.2
Guan, K.L.3
-
49
-
-
84859778293
-
M. MTOR signaling in growth control and disease
-
Laplante, M., Sabatini, D. M. mTOR signaling in growth control and disease. Cell 149, 274-293 (2012).
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.2
-
50
-
-
85006768050
-
The Metabolism of Tumors in the Body
-
Warburg, O., Wind, F., Negelein, E. The Metabolism of Tumors in the Body. The Journal of general physiology 8, 519-530 (1927).
-
(1927)
The Journal of General Physiology
, vol.8
, pp. 519-530
-
-
Warburg, O.1
Wind, F.2
Negelein, E.3
-
51
-
-
27144509163
-
A network-based analysis of systemic inflammation in humans
-
Calvano, S. E. et al. A network-based analysis of systemic inflammation in humans. Nature 437, 1032-1037 (2005).
-
(2005)
Nature
, vol.437
, pp. 1032-1037
-
-
Calvano, S.E.1
-
52
-
-
84865197492
-
Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells
-
Everts, B. et al. Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells. Blood 120, 1422-1431 (2012).
-
(2012)
Blood
, vol.120
, pp. 1422-1431
-
-
Everts, B.1
-
53
-
-
84890288918
-
Tuberous sclerosis 1 (Tsc1)-dependent metabolic checkpoint controls development of dendritic cells
-
Wang, Y. et al. Tuberous sclerosis 1 (Tsc1)-dependent metabolic checkpoint controls development of dendritic cells. Proc Natl Acad Sci USA 110, E4894-4903 (2013).
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. E4894-4903
-
-
Wang, Y.1
-
54
-
-
27744565691
-
Metformin revisited: Re-evaluation of its properties and role in the pharmacopoeia of modern antidiabetic agents
-
Goodarzi, M. O., Bryer-Ash, M. Metformin revisited: re-evaluation of its properties and role in the pharmacopoeia of modern antidiabetic agents. Diabetes, obesity & metabolism 7, 654-665 (2005).
-
(2005)
Diabetes, Obesity & Metabolism
, vol.7
, pp. 654-665
-
-
Goodarzi, M.O.1
Bryer-Ash, M.2
-
55
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou, G. et al. Role of AMP-activated protein kinase in mechanism of metformin action. The Journal of clinical investigation 108, 1167-1174 (2001).
-
(2001)
The Journal of Clinical Investigation
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
-
56
-
-
0014209755
-
Feed-forward activation and feed-back inhibition of pyruvate kinase type L of rat liver
-
Tanaka, T., Sue, F., Morimura, H. Feed-forward activation and feed-back inhibition of pyruvate kinase type L of rat liver. Biochemical and biophysical research communications 29, 444-449 (1967).
-
(1967)
Biochemical and Biophysical Research Communications
, vol.29
, pp. 444-449
-
-
Tanaka, T.1
Sue, F.2
Morimura, H.3
-
57
-
-
84930762844
-
Metformin inhibits monocyte-to-macrophage differentiation via AMPK-mediated inhibition of STAT3 activation: Potential role in atherosclerosis
-
Vasamsetti, S. B. et al. Metformin inhibits monocyte-to-macrophage differentiation via AMPK-mediated inhibition of STAT3 activation: potential role in atherosclerosis. Diabetes 64, 2028-2041 (2015).
-
(2015)
Diabetes
, vol.64
, pp. 2028-2041
-
-
Vasamsetti, S.B.1
-
58
-
-
77953914366
-
Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor
-
Marigo, I. et al. Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor. Immunity 32, 790-802 (2010).
-
(2010)
Immunity
, vol.32
, pp. 790-802
-
-
Marigo, I.1
-
59
-
-
79951634979
-
2-Gy whole-body irradiation significantly alters the balance of CD4 + CD25-T effector cells and CD4 + CD25 + Foxp3 + T regulatory cells in mice
-
Qu, Y. et al. 2-Gy whole-body irradiation significantly alters the balance of CD4 + CD25-T effector cells and CD4 + CD25 + Foxp3 + T regulatory cells in mice. Cellular & molecular immunology 7, 419-427 (2010).
-
(2010)
Cellular & Molecular Immunology
, vol.7
, pp. 419-427
-
-
Qu, Y.1
-
60
-
-
0343185921
-
Nitric oxide-producing CD11b(+ )Ly-6G(Gr-1)(+ )CD31(ER-MP12)(+ ) cells in the spleen of cyclophosphamidetreated mice: Implications for T-cell responses in immunosuppressed mice
-
Angulo, I. et al. Nitric oxide-producing CD11b(+ )Ly-6G(Gr-1)(+ )CD31(ER-MP12)(+ ) cells in the spleen of cyclophosphamidetreated mice: implications for T-cell responses in immunosuppressed mice. Blood 95, 212-220 (2000).
-
(2000)
Blood
, vol.95
, pp. 212-220
-
-
Angulo, I.1
-
61
-
-
84903625194
-
The inhibitory effect of IFN-gamma on protease HTRA1 expression in rheumatoid arthritis
-
Hou, Y. et al. The inhibitory effect of IFN-gamma on protease HTRA1 expression in rheumatoid arthritis. J Immunol 193, 130-138 (2014).
-
(2014)
J Immunol
, vol.193
, pp. 130-138
-
-
Hou, Y.1
|