PSGL-1 and mTOR regulate translation of ROCK-1 and physiological functions of macrophages

EMBO Journal

Volumn 26, Issue 2, 2007, Pages 505-515

  Fox, Richard ^a   Nhan, Thomas Q ^a   Law, G Lynn ^a   Morris, David R ^a   Liles, W Conrad ^a,b   Schwartz, Stephen M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

mTOR; Rapamycin sirolimus; ROCK 1; Translation

Indexed keywords

LYMPHOCYTE ANTIGEN; MAMMALIAN TARGET OF RAPAMYCIN; P SELECTIN GLYCOPROTEIN LIGAND 1; P SELECTIN GLYCOPROTEIN LIGAND 2; RAPAMYCIN; RHO KINASE; RHO KINASE 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CATALYSIS; CELL ADHESION; CONTROLLED STUDY; CYTOPLASM; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOREGULATION; MACROPHAGE ACTIVATION; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION; RECEPTOR INTRINSIC ACTIVITY; RIBOSOME; SIGNAL TRANSDUCTION; TRANSLATION REGULATION; UPREGULATION;

ANIMALS; CELL ADHESION; CELLS, CULTURED; GENE EXPRESSION REGULATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MACROPHAGES, PERITONEAL; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; ONCOGENE PROTEIN V-AKT; PROTEIN BIOSYNTHESIS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES;

MUS;

EID: 33846529557     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601522     Document Type: Article

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