메뉴 건너뛰기




Volumn 95, Issue 1, 2000, Pages 212-220

Nitric oxide-producing CD11b+Ly-6G(Gr-1)+CD31(ER-MP12)+ cells in the spleen of cyclophosphamide-treated mice: Implications for T-cell responses in immunosuppressed mice

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CYCLOPHOSPHAMIDE; NITRIC OXIDE;

EID: 0343185921     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v95.1.212.001k27_212_220     Document Type: Article
Times cited : (142)

References (60)
  • 1
    • 0032170052 scopus 로고    scopus 로고
    • Immune reconstitution and immunotherapy after autologous hematopoietic stem cell transplantation
    • Guillaume T, Rubinstein DB, Symann M. Immune reconstitution and immunotherapy after autologous hematopoietic stem cell transplantation. Blood. 1998;92:1471-1490.
    • (1998) Blood , vol.92 , pp. 1471-1490
    • Guillaume, T.1    Rubinstein, D.B.2    Symann, M.3
  • 2
    • 0030796636 scopus 로고    scopus 로고
    • Immunological reconstitution following bone marrow transplantation
    • Parkman R, Weinberg KI. Immunological reconstitution following bone marrow transplantation. Immunol Rev. 1997;157:73-78.
    • (1997) Immunol Rev , vol.157 , pp. 73-78
    • Parkman, R.1    Weinberg, K.I.2
  • 3
    • 0002040980 scopus 로고    scopus 로고
    • Covalent-DNA binding drugs
    • Perry MC, ed. Baltimore, MD: Williams & Wilkins
    • Grochow LB. Covalent-DNA binding drugs. In: Perry MC, ed. The Chemotherapy Source Book. Baltimore, MD: Williams & Wilkins; 1996:293-316.
    • (1996) The Chemotherapy Source Book , pp. 293-316
    • Grochow, L.B.1
  • 4
    • 0017112677 scopus 로고
    • Limited proliferation of stem cells surviving alkylating agents
    • Botnick LE, Hannon EC, Hellman S. Limited proliferation of stem cells surviving alkylating agents. Nature. 1976;262:68-70.
    • (1976) Nature , vol.262 , pp. 68-70
    • Botnick, L.E.1    Hannon, E.C.2    Hellman, S.3
  • 5
    • 0021992902 scopus 로고
    • Effects of in vitro purging with 4-hydroperoxycy-clophosphamide on the hematopoietic and microenvironmental elements of human bone marrow
    • Siena S, Castro-Malaspina H, Gulati SC, et al. Effects of in vitro purging with 4-hydroperoxycy-clophosphamide on the hematopoietic and microenvironmental elements of human bone marrow. Blood. 1985;65:655-662.
    • (1985) Blood , vol.65 , pp. 655-662
    • Siena, S.1    Castro-Malaspina, H.2    Gulati, S.C.3
  • 6
    • 0018888589 scopus 로고
    • Inhibition of in vitro antibody synthesis by cyclophosphamide-induced suppressor cells
    • Braciale VL, Parish CR: Inhibition of in vitro antibody synthesis by cyclophosphamide-induced suppressor cells. Cell Immunol. 1980;51:1-12.
    • (1980) Cell Immunol , vol.51 , pp. 1-12
    • Braciale, V.L.1    Parish, C.R.2
  • 7
    • 0021997551 scopus 로고
    • Cyclophosphamide-induced suppressor cells in mice: Suppression of the antibody response in vitro and characterization of the effector cells
    • Segre M, Tomei E, Segre D. Cyclophosphamide-induced suppressor cells in mice: suppression of the antibody response in vitro and characterization of the effector cells. Cell Immunol. 1985;91: 443-454.
    • (1985) Cell Immunol , vol.91 , pp. 443-454
    • Segre, M.1    Tomei, E.2    Segre, D.3
  • 9
    • 0023639559 scopus 로고
    • Stimulation of suppressor cells in the bone marrow and spleens of high dose cyclophosphamide-treated C57BL/6 mice
    • Nikcevich DA, Duffie GP, Young MR, Ellis NK, Kaufman GE, Wepsic HT. Stimulation of suppressor cells in the bone marrow and spleens of high dose cyclophosphamide-treated C57BL/6 mice. Cell Immunol. 1987;109:349-359.
    • (1987) Cell Immunol , vol.109 , pp. 349-359
    • Nikcevich, D.A.1    Duffie, G.P.2    Young, M.R.3    Ellis, N.K.4    Kaufman, G.E.5    Wepsic, H.T.6
  • 10
    • 0024346258 scopus 로고
    • Murine natural suppressor cells in the newborn, in bone marrow, and after cyclophosphamide. Genetic variations and dependence on IFN-γ
    • Maier T, Holda JH, Claman HN. Murine natural suppressor cells in the newborn, in bone marrow, and after cyclophosphamide. Genetic variations and dependence on IFN-γ. J Immunol. 1989;143: 491-498.
    • (1989) J Immunol , vol.143 , pp. 491-498
    • Maier, T.1    Holda, J.H.2    Claman, H.N.3
  • 11
    • 0024451925 scopus 로고
    • Reconstitution of cytolytic alloreactivity with N-[4-[(4-fluorophenyl)sulfonyl]phenyl]acetamide (CL 259,763) in animals immunocompromised by cyclophosphamide
    • Wang BS, Lumanglas AL, James JP, et al. Reconstitution of cytolytic alloreactivity with N-[4-[(4-fluorophenyl)sulfonyl]phenyl]acetamide (CL 259,763) in animals immunocompromised by cyclophosphamide. Int J Immunopharmacol. 1989; 11:479-486.
    • (1989) Int J Immunopharmacol , vol.11 , pp. 479-486
    • Wang, B.S.1    Lumanglas, A.L.2    James, J.P.3
  • 12
    • 0027499281 scopus 로고
    • Heterogeneity ot splenic natural suppressor cells induced in mice by treatment with cyclophosphamide
    • Brooks-Kaiser JC, Bourque LA, Hoskin DW. Heterogeneity ot splenic natural suppressor cells induced in mice by treatment with cyclophosphamide. Immunopharmacology. 1993;25:117-129.
    • (1993) Immunopharmacology , vol.25 , pp. 117-129
    • Brooks-Kaiser, J.C.1    Bourque, L.A.2    Hoskin, D.W.3
  • 13
    • 0001509578 scopus 로고
    • Mammalian nitrate biosynthesis: Mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide
    • Stuehr DJ, Marletta MA. Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc Natl Acad Sci U S A. 1985; 82:7738-7742.
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 7738-7742
    • Stuehr, D.J.1    Marletta, M.A.2
  • 14
  • 15
    • 0028902552 scopus 로고
    • Nitric oxide synthases: Properties and catalytic mechanism
    • Griffith OW, Stuehr DJ. Nitric oxide synthases: properties and catalytic mechanism. Ann Rev Physiol. 1995;57:707-736.
    • (1995) Ann Rev Physiol , vol.57 , pp. 707-736
    • Griffith, O.W.1    Stuehr, D.J.2
  • 16
    • 0025942326 scopus 로고
    • Nitric oxide production is required for murine resident peritoneal macrophages to suppress mitogen-stimulated T cell proliferation
    • Albina JE, Abate JA, Henry WL Jr. Nitric oxide production is required for murine resident peritoneal macrophages to suppress mitogen-stimulated T cell proliferation. J Immunol. 1991;147: 144-148.
    • (1991) J Immunol , vol.147 , pp. 144-148
    • Albina, J.E.1    Abate, J.A.2    Henry W.L., Jr.3
  • 17
    • 0026712298 scopus 로고
    • Immunosuppression induced by nitric oxide and its inhibition by interleukin-4
    • al-Ramadi BK, Meissler JJ Jr, Huang D, Eisenstein TK. Immunosuppression induced by nitric oxide and its inhibition by interleukin-4. Eur J Immunol. 1992;22:2249-2254.
    • (1992) Eur J Immunol , vol.22 , pp. 2249-2254
    • Al-Ramadi, B.K.1    Meissler J.J., Jr.2    Huang, D.3    Eisenstein, T.K.4
  • 18
    • 0027382922 scopus 로고
    • Suppressor macrophages in African trypanosomiasis inhibit T cell proliferative responses by nitric oxide and prostaglandins
    • Schleifer KW, Mansfield JM. Suppressor macrophages in African trypanosomiasis inhibit T cell proliferative responses by nitric oxide and prostaglandins. J Immunol. 1993;151:5492-5503.
    • (1993) J Immunol , vol.151 , pp. 5492-5503
    • Schleifer, K.W.1    Mansfield, J.M.2
  • 19
    • 0027250110 scopus 로고
    • Characterization of the immunosuppressive effects of nitric oxide in graft-versus-host disease
    • Hoffman RA, Langrerh JM, Wren SM, et al. Characterization of the immunosuppressive effects of nitric oxide in graft-versus-host disease. J Immunol. 1993;151:1508-1518.
    • (1993) J Immunol , vol.151 , pp. 1508-1518
    • Hoffman, R.A.1    Langrerh, J.M.2    Wren, S.M.3
  • 20
    • 0032531093 scopus 로고    scopus 로고
    • Treatment of Paracoccidioides brasiliensis-infected mice with a nitric oxide inhibitor prevents the failure of cell-mediated immune response
    • Bocca AL, Hayashi EE, Pinheiro AG, et al. Treatment of Paracoccidioides brasiliensis-infected mice with a nitric oxide inhibitor prevents the failure of cell-mediated immune response. J Immunol. 1998;161:3056-3063.
    • (1998) J Immunol , vol.161 , pp. 3056-3063
    • Bocca, A.L.1    Hayashi, E.E.2    Pinheiro, A.G.3
  • 21
    • 0029065835 scopus 로고
    • Involvement of nitric oxide in bone marrow-derived natural suppressor activity. Its dependence on IFN-γ
    • Angulo I, Rodriguez R, García B, Medina M, Navarro J, Subiza JL. Involvement of nitric oxide in bone marrow-derived natural suppressor activity. Its dependence on IFN-γ. J Immunol. 1995;155: 15-26.
    • (1995) J Immunol , vol.155 , pp. 15-26
    • Angulo, I.1    Rodriguez, R.2    García, B.3    Medina, M.4    Navarro, J.5    Subiza, J.L.6
  • 26
    • 0029994319 scopus 로고    scopus 로고
    • Interferon-γ: Biology and role in pathogenesis
    • Billiau A. Interferon-γ: biology and role in pathogenesis. Adv Immunol. 1996;62:61-130.
    • (1996) Adv Immunol , vol.62 , pp. 61-130
    • Billiau, A.1
  • 27
    • 0028041170 scopus 로고
    • Monoclonal antibodies to murine CD40 define two distinct functional epitopes
    • Heath AW, Wu WW, Howard MC. Monoclonal antibodies to murine CD40 define two distinct functional epitopes. Eur J Immunol. 1994;24:1828-1834.
    • (1994) Eur J Immunol , vol.24 , pp. 1828-1834
    • Heath, A.W.1    Wu, W.W.2    Howard, M.C.3
  • 28
    • 0025559814 scopus 로고
    • Regulation of in vivo expression of Fc receptors for IgE (Fc∈R) on murine lymphocytes. II. Induction of Fc∈R and its inhibition in mice immunized with antigen
    • Kiniwa M, Yanagiara Y, Tasaka K. Regulation of in vivo expression of Fc receptors for IgE (Fc∈R) on murine lymphocytes. II. Induction of Fc∈R and its inhibition in mice immunized with antigen. Int Arch Allergy Appl Immunol. 1990;93:242-248.
    • (1990) Int Arch Allergy Appl Immunol , vol.93 , pp. 242-248
    • Kiniwa, M.1    Yanagiara, Y.2    Tasaka, K.3
  • 29
    • 0026775653 scopus 로고
    • Production of nitric oxide by murine bone marrow cells: Inverse correlation with cellular proliferation
    • Punjabi CJ, Laskin DL, Heck DE, Laskin JD. Production of nitric oxide by murine bone marrow cells: inverse correlation with cellular proliferation. J Immunol. 1992;149:2179-2184.
    • (1992) J Immunol , vol.149 , pp. 2179-2184
    • Punjabi, C.J.1    Laskin, D.L.2    Heck, D.E.3    Laskin, J.D.4
  • 30
    • 0029081523 scopus 로고
    • Nitric oxide suppression of human hematopoiesis in vitro. Contribution to inhibitory action of interferon-γ and tumor necrosis factor-á
    • Maciejewski JP, Selleri C, Sato T, et al. Nitric oxide suppression of human hematopoiesis in vitro. Contribution to inhibitory action of interferon-γ and tumor necrosis factor-á. J Clin Invest. 1995; 96:1085-1092.
    • (1995) J Clin Invest , vol.96 , pp. 1085-1092
    • Maciejewski, J.P.1    Selleri, C.2    Sato, T.3
  • 31
    • 0029098304 scopus 로고
    • Cytokine and nitric oxide regulation of the immunosuppression in Trypanosoma cruzi infection
    • Abrahamsohn IA, Coffman RL. Cytokine and nitric oxide regulation of the immunosuppression in Trypanosoma cruzi infection. J Immunol. 1995; 155:3955-3963.
    • (1995) J Immunol , vol.155 , pp. 3955-3963
    • Abrahamsohn, I.A.1    Coffman, R.L.2
  • 32
    • 0029742960 scopus 로고    scopus 로고
    • Interferon-gamma suppresses T-cell proliferation to mitogen via the nitric oxide pathway during experimental acute graft-versus-host disease
    • Krenger W, Falzarano G, Delmonte J Jr. Snyder KM, Byon JC, Ferrara JL. Interferon-gamma suppresses T-cell proliferation to mitogen via the nitric oxide pathway during experimental acute graft-versus-host disease. Blood. 1996;88:1113-1121.
    • (1996) Blood , vol.88 , pp. 1113-1121
    • Krenger, W.1    Falzarano, G.2    Delmonte J., Jr.3    Snyder, K.M.4    Byon, J.C.5    Ferrara, J.L.6
  • 34
    • 0030059765 scopus 로고    scopus 로고
    • Suppression of T cell proliferation by tumor-induced granulocyte-macrophage progenitor cells producing transforming growth factor-β and nitric oxide
    • Young MR, Wright MA, Matthews JP, Malik I, Prechel M. Suppression of T cell proliferation by tumor-induced granulocyte-macrophage progenitor cells producing transforming growth factor-β and nitric oxide. J Immunol. 1996;156:1916-1922.
    • (1996) J Immunol , vol.156 , pp. 1916-1922
    • Young, M.R.1    Wright, Ma.2    Matthews, J.P.3    Malik, I.4    Prechel, M.5
  • 35
    • 0030459045 scopus 로고    scopus 로고
    • Role of nitric oxide in hematosuppression and benzene-induced toxicity
    • Laskin DL, Heck DE, Punjabi CJ, Laskin JD. Role of nitric oxide in hematosuppression and benzene-induced toxicity. Environ Health Perspect. 1996;104(suppl):1283-1287.
    • (1996) Environ Health Perspect , vol.104 , Issue.SUPPL. , pp. 1283-1287
    • Laskin, D.L.1    Heck, D.E.2    Punjabi, C.J.3    Laskin, J.D.4
  • 36
    • 0032526629 scopus 로고    scopus 로고
    • Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/ STAT5 signaling pathway
    • Bingisser RM, Tilbrook PA, Holt PG, Kees UR. Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/ STAT5 signaling pathway. J Immunol. 1998;160: 5729-5734.
    • (1998) J Immunol , vol.160 , pp. 5729-5734
    • Bingisser, R.M.1    Tilbrook, P.A.2    Holt, P.G.3    Kees, U.R.4
  • 37
    • 0029903812 scopus 로고    scopus 로고
    • Inhibition of endothelial cell proliferation and bFGF-induced phenotypic modulation by nitric oxide
    • RayChaudhury A, Frischer H, Malik AB. Inhibition of endothelial cell proliferation and bFGF-induced phenotypic modulation by nitric oxide. J Cell Biochem. 1996;63:125-134.
    • (1996) J Cell Biochem , vol.63 , pp. 125-134
    • RayChaudhury, A.1    Frischer, H.2    Malik, A.B.3
  • 38
    • 0030731917 scopus 로고    scopus 로고
    • Nitric oxide primes pancreatic β cells for Fas-mediated destruction in insulin-dependent diabetes mellitus
    • Stassi G, De Maria R, Trucco WR, Testi R, Galuzzo A, Giordano C, Trucco M. Nitric oxide primes pancreatic β cells for Fas-mediated destruction in insulin-dependent diabetes mellitus. J Exp Med. 1997;186:1193-1200.
    • (1997) J Exp Med , vol.186 , pp. 1193-1200
    • Stassi, G.1    De Maria, R.2    Trucco, W.R.3    Testi, R.4    Galuzzo, A.5    Giordano, C.6    Trucco, M.7
  • 39
    • 0027231742 scopus 로고
    • Nitric oxide-mediated apoptosis in murine peritoneal macrophages
    • Albina JE, Cui S, Mateo RB, Reichner JS. Nitric oxide-mediated apoptosis in murine peritoneal macrophages. J Immunol. 1993;150:5080-5085.
    • (1993) J Immunol , vol.150 , pp. 5080-5085
    • Albina, J.E.1    Cui, S.2    Mateo, R.B.3    Reichner, J.S.4
  • 42
    • 0032526840 scopus 로고    scopus 로고
    • Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation
    • Munder M, Mallo M, Eichmann K, Modolell M. Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation. J Exp Med. 1998;187: 2103-2108.
    • (1998) J Exp Med , vol.187 , pp. 2103-2108
    • Munder, M.1    Mallo, M.2    Eichmann, K.3    Modolell, M.4
  • 43
    • 0028277327 scopus 로고
    • Control of T lymphocyte activation and IL-2 receptor expression by endogenously secreted lymphokines
    • Pimentel-Muiños FX, Muñoz-Fernández MA, Fresno M. Control of T lymphocyte activation and IL-2 receptor expression by endogenously secreted lymphokines. J Immunol. 1994;152:5714-5722.
    • (1994) J Immunol , vol.152 , pp. 5714-5722
    • Pimentel-Muiños, F.X.1    Muñoz-Fernández, M.A.2    Fresno, M.3
  • 44
    • 0030046808 scopus 로고    scopus 로고
    • CD40-gp39 interactions play a critical role during allograft rejection. Suppression of allograft rejection by blockade of the CD40-gp39 pathway
    • Larsen CP, Alexander DZ, Hollenbaugh D, et al. CD40-gp39 interactions play a critical role during allograft rejection. Suppression of allograft rejection by blockade of the CD40-gp39 pathway. Transplantation. 1996;61:4-9.
    • (1996) Transplantation , vol.61 , pp. 4-9
    • Larsen, C.P.1    Alexander, D.Z.2    Hollenbaugh, D.3
  • 45
    • 0028898462 scopus 로고
    • Activated T cells enhance nitric oxide production by murine splenic macrophages through gp39 and LFA-1
    • Tian L, Noelle RJ, Lawrence DA. Activated T cells enhance nitric oxide production by murine splenic macrophages through gp39 and LFA-1. Eur J Immunol. 1995;25:306-309.
    • (1995) Eur J Immunol , vol.25 , pp. 306-309
    • Tian, L.1    Noelle, R.J.2    Lawrence, D.A.3
  • 46
    • 0030470417 scopus 로고    scopus 로고
    • Nitric oxide production by bone marrow-derived dendritic cells: Implications for the regulation of allogenic T cell responses
    • Bonham CA, Lu L, Li Y, Huffman RA, Simmons RL, Thomson AW. Nitric oxide production by bone marrow-derived dendritic cells: implications for the regulation of allogenic T cell responses. Transplantation. 1996;62:1871-1877.
    • (1996) Transplantation , vol.62 , pp. 1871-1877
    • Bonham, C.A.1    Lu, L.2    Li, Y.3    Huffman, R.A.4    Simmons, R.L.5    Thomson, A.W.6
  • 47
    • 0027272534 scopus 로고
    • Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. R86-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family
    • Fleming TJ, Fleming ML, Malek TR. Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. R86-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family. J Immunol. 1993;151: 2399-2408.
    • (1993) J Immunol , vol.151 , pp. 2399-2408
    • Fleming, T.J.1    Fleming, M.L.2    Malek, T.R.3
  • 49
    • 0031058635 scopus 로고    scopus 로고
    • Structural identification of the hematopoietic progenitor antigen ER-MP12 as the vascular endothelial adhesion molecule PECAM-1 (CD31)
    • Ling V, Luxenberg D, Wang J, et al. Structural identification of the hematopoietic progenitor antigen ER-MP12 as the vascular endothelial adhesion molecule PECAM-1 (CD31). Eur J Immunol. 1997;27:509-514.
    • (1997) Eur J Immunol , vol.27 , pp. 509-514
    • Ling, V.1    Luxenberg, D.2    Wang, J.3
  • 50
    • 0024439774 scopus 로고
    • + hematopoietic stem cells in the peripheral blood of high-dose cyclophosphamide-treated patients: Enhancement by intravenous recombinant human granulocyte-macrophage colony-stimulating factors
    • + hematopoietic stem cells in the peripheral blood of high-dose cyclophosphamide-treated patients: enhancement by intravenous recombinant human granulocyte-macrophage colony-stimulating factors. Blood. 1989;74:1905-1914.
    • (1989) Blood , vol.74 , pp. 1905-1914
    • Siena, S.1    Bregni, M.2    Brando, B.3    Ravagnani, F.4    Bonadonna, G.5    Gianni, A.M.6
  • 51
    • 0031059252 scopus 로고    scopus 로고
    • Cyclophosphamide/granulocyle colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization
    • Morrison SJ, Wright DE, Weissman IL. Cyclophosphamide/granulocyle colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization. Proc Natl Acad Sci U S A. 1997;94:1908-1913.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 1908-1913
    • Morrison, S.J.1    Wright, D.E.2    Weissman, I.L.3
  • 52
    • 0029561771 scopus 로고
    • Nitric oxide in human hematopoiesis
    • Ouaaz F. Nitric oxide in human hematopoiesis. Res Immunol. 1995;146:678-681.
    • (1995) Res Immunol , vol.146 , pp. 678-681
    • Ouaaz, F.1
  • 53
    • 0028080983 scopus 로고
    • + natural suppressor cells on IL-2 and IL-4 utilization in MLR
    • + natural suppressor cells on IL-2 and IL-4 utilization in MLR. Transplantation. 1994;58:1096-1103.
    • (1994) Transplantation , vol.58 , pp. 1096-1103
    • Brooks, J.C.1    Hoskin, D.W.2
  • 54
    • 0032534664 scopus 로고    scopus 로고
    • Nitric oxide synthase plays a signaling role in TcR-triggered apoptotic death
    • Williams MS, Noguchi S, Henkart PA, Osawa Y. Nitric oxide synthase plays a signaling role in TcR-triggered apoptotic death. J Immunol. 1998; 161:6526-6531.
    • (1998) J Immunol , vol.161 , pp. 6526-6531
    • Williams, M.S.1    Noguchi, S.2    Henkart, P.A.3    Osawa, Y.4
  • 56
    • 0030780577 scopus 로고    scopus 로고
    • Interleukin-12 is critical for induction of nitric oxide-mediated immunosuppression following vaccination of mice with attenuated Salmonella typhimurium
    • Schwacha MG, Eisenstein TK. Interleukin-12 is critical for induction of nitric oxide-mediated immunosuppression following vaccination of mice with attenuated Salmonella typhimurium. Infect Immun. 1997;65:4897-4903.
    • (1997) Infect Immun , vol.65 , pp. 4897-4903
    • Schwacha, M.G.1    Eisenstein, T.K.2
  • 57
    • 0032476615 scopus 로고    scopus 로고
    • Immune suppression by recombinant interleukin (rlL)-12 involves interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: Inhibitors of NO generation reveal the extent of rlL-12 vaccine adjuvant effect
    • Koblish HK, Hunter CA, Wysocka M, Trinchieri G, Lee WM. Immune suppression by recombinant interleukin (rlL)-12 involves interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: inhibitors of NO generation reveal the extent of rlL-12 vaccine adjuvant effect. J Exp Med. 1998;188:1603-1610.
    • (1998) J Exp Med , vol.188 , pp. 1603-1610
    • Koblish, H.K.1    Hunter, C.A.2    Wysocka, M.3    Trinchieri, G.4    Lee, W.M.5
  • 58
    • 0033136294 scopus 로고    scopus 로고
    • Different doses of adenoviral vector expressing IL-12 enhance or depress the immune response to a coadministered antigen: The role of nitric oxide
    • Lasarte JJ, Corrales FJ, Casares N, et al. Different doses of adenoviral vector expressing IL-12 enhance or depress the immune response to a coadministered antigen: the role of nitric oxide. J Immunol. 1999;162:5270-5277.
    • (1999) J Immunol , vol.162 , pp. 5270-5277
    • Lasarte, J.J.1    Corrales, F.J.2    Casares, N.3
  • 59
    • 0031670153 scopus 로고    scopus 로고
    • Nitric oxide-induced apoptotic cell death in the acute phase of Trypanosoma cruzi infection in mice
    • Martins GA, Cardoso MAG, Aliberti JCS, Silva JS. Nitric oxide-induced apoptotic cell death in the acute phase of Trypanosoma cruzi infection in mice. Immunol Lett. 1998;63:113-120.
    • (1998) Immunol Lett , vol.63 , pp. 113-120
    • Martins, G.A.1    Cardoso, M.A.G.2    Aliberti, J.C.S.3    Silva, J.S.4
  • 60
    • 0032423716 scopus 로고    scopus 로고
    • Nitric oxide synthase expression in macrophages of Histoplasma capsulatum-infected mice is associated with splenocyte apoptosis and unresponsiveness
    • Wu-Hsieh BA, Chen W, Lee H. Nitric oxide synthase expression in macrophages of Histoplasma capsulatum-infected mice is associated with splenocyte apoptosis and unresponsiveness. Infect Immun. 1998;66:5520-5526.
    • (1998) Infect Immun , vol.66 , pp. 5520-5526
    • Wu-Hsieh, B.A.1    Chen, W.2    Lee, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.