Rapamycin inhibits lipopolysaccharide induction of granulocyte-colony stimulating factor and inducible nitric oxide synthase expression in macrophages by reducing the levels of octamer-binding factor-2

FEBS Journal

Volumn 278, Issue 1, 2011, Pages 85-96

  Chou, Yuan Yi ^a   Gao, Jhen I ^a   Chang, Shwu Fen ^b   Chang, Po Yuan ^c   Lu, Shao Chun ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

granulocyte colony stimulating factor (G CSF); inducible nitric oxide synthase (iNOS); lipopolysaccharide (LPS); macrophage; mammalian target of rapamycin (mTOR); octamer binding factor 2 (Oct 2); rapamycin

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MAMMALIAN TARGET OF RAPAMYCIN; OCTAMER TRANSCRIPTION FACTOR 2; RAPAMYCIN;

ANIMAL CELL; ARTICLE; CELL ASSAY; CELL STIMULATION; CHROMATIN IMMUNOPRECIPITATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME INHIBITOR INTERACTION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; UPREGULATION;

ANIMALS; CELL LINE; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GRANULOCYTE COLONY-STIMULATING FACTOR; HUMANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NITRIC OXIDE SYNTHASE TYPE II; OCTAMER TRANSCRIPTION FACTOR-2; PROMOTER REGIONS, GENETIC; SIROLIMUS;

MAMMALIA;

EID: 78650465760     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2010.07929.x     Document Type: Article

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