Mechanism of allosteric activation of TMEM16A/ANO1 channels by a commonly used chloride channel blocker

British Journal of Pharmacology

Volumn 173, Issue 3, 2016, Pages 511-528

  Ta, Chau M ^a   Adomaviciene, Aiste ^a   Rorsman, Nils J G ^a,b   Garnett, Hannah ^a,c   Tammaro, Paolo ^a,c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

9 ANTHROIC ACID; ANOCTAMIN 1; CALCIUM ACTIVATED CHLORIDE CHANNEL; CALCIUM ION; CHLORIDE CHANNEL BLOCKING AGENT; CHLORIDE ION; UNCLASSIFIED DRUG; 9-ANTHROIC ACID; ANTHRACENE DERIVATIVE; CHLORIDE CHANNEL; TMEM16A PROTEIN, MOUSE;

ALLOSTERISM; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BINDING SITE; CALCIUM CELL LEVEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG MECHANISM; ELECTROPHYSIOLOGY; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PATCH CLAMP TECHNIQUE; PRIORITY JOURNAL; STEADY STATE; ANTAGONISTS AND INHIBITORS; CHANNEL GATING; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; PHYSIOLOGY;

ANTHRACENES; BINDING SITES; CHLORIDE CHANNELS; HEK293 CELLS; HUMANS; ION CHANNEL GATING;

EID: 84956595435     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13381     Document Type: Article

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