Flufenamic acid as an ion channel modulator

Pharmacology and Therapeutics

Volumn 138, Issue 2, 2013, Pages 272-284

  Guinamard, Romain ^a,b   Simard, Christophe ^a,b   Del Negro, Christopher ^c  

^a NORMANDIE UNIVERSITÉ   (France)

^b France   (France)

^c The College of William and Mary   (United States)

Author keywords

Channel blockers; Chloride channels; Flufenamate; Flufenamic acid; Non selective cation channel; TRP

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; CALCIUM ION; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FENAMIC ACID DERIVATIVE; FLUFENAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POTASSIUM CHANNEL KV1.1; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; TRANSIENT RECEPTOR POTENTIAL CHANNEL 4; TRANSIENT RECEPTOR POTENTIAL CHANNEL 5; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6; TRANSIENT RECEPTOR POTENTIAL CHANNEL 7; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M2; TRANSIENT RECEPTOR POTENTIAL CHANNEL M3; TRANSIENT RECEPTOR POTENTIAL CHANNEL M4; TRANSIENT RECEPTOR POTENTIAL CHANNEL M5; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 3; VANILLOID RECEPTOR 4; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

CANCER CELL CULTURE; CHLORIDE CURRENT; CYSTIC FIBROSIS; DRUG EFFICACY; DRUG PENETRATION; GAP JUNCTION; HUMAN; IC 50; NONHUMAN; PRIORITY JOURNAL; RABBIT; REVIEW; SKELETAL MUSCLE; SPODOPTERA LITTORALIS; SYNAPTIC INHIBITION; XENOPUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; FLUFENAMIC ACID; HUMANS; ION CHANNELS; PATCH-CLAMP TECHNIQUES; PROTEIN BINDING;

EID: 84875211004     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2013.01.012     Document Type: Review

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