Mechanisms of block of muscle type CLC chloride channels (review)

Molecular Membrane Biology

Volumn 19, Issue 4, 2002, Pages 285-292

  Pusch, Michael ^a   Accardi, Alessio ^a   Liantonio, Antonella ^a   Guida, Patrizia ^a   Traverso, Sonia ^a   Conte Camerino, Diana ^b   Conti, Franco ^a  

^a CNR   (Italy)

^b NONE

Author keywords

9AC; Anion channel; CPP; Double barrelled; Gating; Pore block; Voltage dependence

Indexed keywords

CHLORIDE CHANNEL; CLC PROTEIN; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

BINDING AFFINITY; BINDING KINETICS; CHIRALITY; MUSCLE; PRIORITY JOURNAL; PROTEIN STRUCTURE; REVIEW;

ANIMALS; CHLORIDE CHANNELS; HUMANS; ION CHANNEL GATING; MUSCLES; TORPEDO;

BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 0036821666     PISSN: 09687688     EISSN: None     Source Type: Journal    
DOI: 10.1080/09687680210166938     Document Type: Review

References (51)

1. Accardi, A. and Pusch, M., 2000, Fast and slow gating relaxations in the muscle chloride channel CLC-1. Journal of General Physiology, 116, 433-444.
2. Accardi, A., Ferrera, L. and Pusch, M., 2001, Drastic reduction of the slow gate of human muscle chloride channel (CIC-1) by mutation C277S. Journal of Physiology, 534, 745-752.
3. Accardi, A., Traverso, S. and Pusch, M., 2002, Investigating the open and closed pore of CLC-0 with CPA. Biophysical Journal, 82, 13a.
4. Aromataris, E. C., Astill, D. S., Rychkov, G. Y., Bryant, S. H., Bretag, A. H. and Roberts, M. L., 1999, Modulation of the gating of CIC-1 by S-(-) 2-(4-chlorophenoxy) propionic acid. British Journal of Pharmacology, 126, 1375-1382.
5. Bauer, C. K., Steinmeyer, K., Schwarz, J. R. and Jentsch, T. J., 1991, Completely functional double-barreled chloride channel expressed from a single Torpedo cDNA. Proceedings of the National Academy of Sciences (USA), 88, 11052-11056.
6. Birkenhäger, R., Otto, E., Schurmann, M. J., Vollmer, M., Ruf, E. M., Maier-Lutz, I., Beekmann, F., Fekete, A., Omran, H., Feldmann, D., Milford, D. V., Jeck, N., Konrad, M., Landau, D., Knoers, N. V., Antignac, C., Sudbrak, R., Kispert, A. and Hildebrandt, F., 2001, Mutation of BSND causes Bartter syndrome with sensorineural deafness and kidney failure. Nature Genetics, 29, 310-314.
7. Bösl, M. R., Stein, V., Hübner, C., Zdebik, A. A., Jordt, S. E., Mukhopadhyay, A. K., Davidoff, M. S., Holstein, A. F. and Jentsch, T. J., 2001, Male germ cells and photoreceptors, both dependent on close cell-cell interactions, degenerate upon CIC-2 CI(-) channel disruption. Embo Journal, 20, 1289-1299.
8. Chen, T. Y., 1998, Extracellular zinc ion inhibits CIC-0 chloride channels by facilitating slow gating. Journal of General Physiology, 112, 715-726.
9. Chen, T. Y. and Miller, C., 1996, Nonequilibrium gating and voltage dependence of the CIC-0 CI-channel. Journal of General Physiology, 108, 237-250.
10. Clark, S., Jordt, S. E., Jentsch, T. J. and Mathie, A., 1998, Characterization of the hyperpolarization-activated chloride current in dissociated rat sympathetic neurons. Journal of Physiology, 506, 665-678.
11. Conte-Camerino, D., Mambrini, M., DeLuca, A., Tricarico, D., Bryant, S. H., Tortorella, V. and Bettoni, G., 1988, Enantiomers of clofibric acid analogs have opposite actions on rat skeletal muscle chloride channels. Pflugers Archiv, 413, 105-107.
12. De Luca, A., Tricarico, D., Wagner, R., Bryant, S. H., Tortorella, V. and Conte Camerino, D., 1992, Opposite effects of enantiomers of clofibric acid derivative on rat skeletal muscle chloride conductance: antagonism studies and theoretical modeling of two different receptor site interactions. Journal of Pharmacology and Experimental Therapy, 260, 364-368.
13. Dutzler, R., Campbell, E. B., Cadene, M., Chait, B. T. and MacKinnon, R., 2002, X-ray structure of a CIC chloride channel at 3.0 A reveals the molecular basis of anion selectivity. Nature, 415, 287-294.
14. Estévez, R., Boettger, T., Stein, V., Birkenhager, R., Otto, E., Hildebrandt, F. and Jentsch, T. J., 2001, Barttin is a CI- channel beta-subunit crucial for renal CI- reabsorption and inner ear K+ secretion. Nature, 414, 558-561.
15. Gadsby, D. C. and Nairn, A. C., 1999, Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis. Physiology Review, 79, S77-S107.
16. Gründer, S., Thiemann, A., Pusch, M. and Jentsch, T. J., 1992, Regions involved in the opening of CIC-2 chloride channel by voltage and cell volume. Nature, 360, 759-762.
17. Hanke, W. and Miller, C., 1983, Single chloride channels from Torpedo electroplax. Activation by protons. Journal of General Physiology, 82, 25-45.
18. Humphrey, W., Dalke, A. and Schulten, K., 1996, VMD: visual molecular dynamics. Journal of Molecular Graphics, 14, 33-38.
19. Jentsch, T. J., Steinmeyer, K. and Schwarz, G., 1990, Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes. Nature, 348, 510-514.
20. Koch, M. C., Steinmeyer, K., Lorenz, C., Ricker, K., Wolf, F., Otto, M., Zoll, B., Lehmann-Horn, F., Grzeschik, K. H. and Jentsch, T. J., 1992, The skeletal muscle chloride channel in dominant and recessive human myotonia. Science, 257, 797-800.
21. Kornak, U., Kasper, D., Bösl, M. R., Kaiser, E., Schweizer, M., Schulz, A., Friedrich, W., Delling, G. and Jentsch, T. J., 2001, Loss of the CIC-7 chloride channel leads to osteopetrosis in mice and man. Cell, 104, 205-215.
22. Kurz, L. L., Klink, H., Jakob, I., Kuchenbecker, M., Benz, S., Lehmann-Horn, F. and Rüdel, R., 1999, Identification of three cysteines as targets for the Zn2+ blockade of the human skeletal muscle chloride channel. Journal of Biological Chemistry, 274, 11687-11692.
23. Liantonio, L., Pusch, M., Accardi, A., De Luca, A., Traverso, S., Pierno, S., Tortorella, P., Fracchiolla, G., Loiodice, F. and Conte Camerino, D., 2002, Various members of the CLC family are differentially affected by newly synthesized clofibric acid derivatives. Biophysical Journal, 82, 241a.
24. Lin, C. W. and Chen, T. Y., 2000, Cysteine modification of a putative pore residue in CIC-0: implication for the pore stoichiometry of CIC chloride channels. Journal of General Physiology, 116, 535-546.
25. Lin, Y. W., Lin, C. W. and Chen, T. Y., 1999, Elimination of the slow gating of CIC-0 chloride channel by a point mutation. Journal of General Physiology, 114, 1-12.
26. Lloyd, S. E., Pearce, S. H., Fisher, S. E., Steinmeyer, K., Schwappach, B., Scheinman, S. J., Harding, B., Bolino, A., Devoto, M., Goodyer, P., Rigden, S. P., Wrong, O., Jentsch, T. J., Craig, I. W. and Thakker, R. V., 1996, A common molecular basis for three inherited kidney stone diseases. Nature, 379, 445-449.
27. Ludewig, U., 1996, Struktur-Funktionsuntersuchungen am klonierten Chloridkanal aus Torpedo marmorata Doctoral Thesis, Fakultät für Physik, Universität Göttingen.
28. Ludewig, U., Jentsch, T. J. and Pusch, M., 1997b, Analysis of a protein region involved in permeation and gating of the voltage-gated Torpedo chloride channel CIC-0. Journal of Physiology, 498, 691-702.
29. Ludewig, U., Pusch, M. and Jentsch, T. J., 1996, Two physically distinct pores in the dimeric CIC-0 chloride channel. Nature, 383, 340-343.
30. Ludewig, U., Pusch, M. and Jentsch, T. J., 1997a, Independent gating of single pores in CLC-0 chloride channels. Biophysics Journal, 73, 789-797.
31. Maduke, M., Miller, C. and Mindell, J. A., 2000, A decade of CLC chloride channels: structure, mechanism, and many unsettled questions. Annual Review of Biophysical and Biomolecular Structures, 29, 411-438.
32. Middleton, R. E., Pheasant, D. J. and Miller, C., 1996, Homodimeric architecture of a CIC-type chloride ion channel. Nature, 383, 337-340.
33. Miller, C., 1982, Open-state substructure of single chloride channels from Torpedo electroplax. Philosophical Transactions of the Royal Society of London B Biological Science, 299, 401-411.
34. Miller, C. and White, M. M., 1984, Dimeric structure of single chloride channels from Torpedo electroplax. Proceedings of the National Academy of Sciences (USA), 81, 2772-2775.
35. Mindell, J. A., Maduke, M., Miller, C. and Grigorieff, N., 2001, Projection structure of a CIC-type chloride channel at 6.5 A resolution. Nature, 409, 219-223.
36. Piwon, N., Günther, W., Schwake, M., Bösl, M. R. and Jentsch, T. J., 2000, CIC-5 CI-channel disruption impairs endocytosis in a mouse model for Dent's disease. Nature, 408, 369-373.
37. Pusch, M., 2002, Myotonia caused by mutations in the muscle chloride channel gene CLCN1. Human Mutation, 19, 423-434.
38. Pusch, M., Accardi, A., Liantonio, A., Ferrera, L., De Luca, A., Camerino, D. C. and Conti, F., 2001, Mechanism of block of single protopores of the Torpedo chloride channel CIC-0 by 2-(p-chlorophenoxy)butyric acid (CPB). Journal of General Physiology, 118, 45-62.
39. Pusch, M., Liantonio, A., Bertorello, L., Accardi, A., De Luca, A., Pierno, S., Tortorella, V. and Camerino, D. C., 2000, Pharmacological characterization of chloride channels belonging to the CIC family by the use of chiral clofibric acid derivatives. Molecular Pharmacology, 58, 498-507.
40. Pusch, M., Ludewig, U. and Jentsch, T. J., 1997, Temperature dependence of fast and slow gating relaxations of CIC-0 chloride channels. Journal of General Physiology, 109, 105-116.
41. Pusch, M., Ludewig, U., Rehfeldt, A. and Jentsch, T. J., 1995, Gating of the voltage-dependent chloride channel CIC-0 by the permeant anion. Nature, 373, 527-531.
42. Rychkov, G. Y., Astill, D. S., Bennetts, B., Hughes, B. P., Bretag, A. H. and Roberts, M. L., 1997, pH-dependent interactions of Cd2+ and a carboxylate blocker with the rat C1C-1 chloride channel and its R304E mutant in the Sf-9 insect cell line. Journal of Physiology, 501, 355-362.
43. Saviane, C., Conti, F. and Pusch, M., 1999, The muscle chloride channel CIC-1 has a double-barreled appearance that is differentially affected in dominant and recessive myotonia. Journal of General Physiology, 113, 457-468.
44. Simon, D. B., Bindra, R. S., Mansfield, T. A., Nelson-Williams, C., Mendonca, E., Stone, R., Schurman, S., Nayir, A., Alpay, H., Bakkaloglu, A., Rodriguez-Soriano, J., Morales, J. M., Sanjad, S. A., Taylor, C. M., Pilz, D., Brem, A., Trachtman, H., Griswold, W., Richard, G. A., John, E. and Lifton, R. P., 1997, Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III. Nature Genetics, 17, 171-178.
45. Steinmeyer, K., Klocke, R., Ortland, C., Gronemeier, M., Jockusch, H., Gründer, S. and Jentsch, T. J., 1991a, Inactivation of muscle chloride channel by transposon insertion in myotonic mice. Nature, 354, 304-308.
46. Steinmeyer, K., Ortland, C. and Jentsch, T. J., 1991b, Primary structure and functional expression of a developmentally regulated skeletal muscle chloride channel. Nature, 354, 301-304.
47. Stobrawa, S. M., Breiderhoff, T., Takamori, S., Engel, D., Schweizer, M., Zdebik, A. A., Bösl, M. R., Ruether, K., Jahn, H., Draguhn, A., Jahn, R. and Jentsch, T. J., 2001, Disruption of CIC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus. Neuron, 29, 185-196.
48. Thiemann, A., Gründer, S., Pusch, M. and Jentsch, T. J., 1992, A chloride channel widely expressed in epithelial and non-epithelial cells. Nature, 356, 57-60.
49. Waldegger, S. and Jentsch, T. J., 2000, Functional and structural analysis of CIC-K chloride channels involved in renal disease. Journal of Biological Chemistry, 275, 24527-24533.
50. Wang, S. S., Devuyst, O., Courtoy, P. J., Wang, X. T., Wang, H., Wang, Y., Thakker, R. V., Guggino, S. and Guggino, W. B., 2000, Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis. Human Molecular Genetics, 9, 2937-2945.
51. Weinreich, F. and Jentsch, T. J., 2001, Pores formed by single subunits in mixed dimers of different CLC chloride channels. Journal of Biological Chemistry, 276, 2347-2353.