-
1
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
Ferlay J, Shin H-R, Bray F, Forman D, Mathers C, Parkin DM (2010) Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 127:2893–2917. doi: 10.1002/ijc.25516
-
(2010)
Int J Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.-R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
3
-
-
33749002551
-
Models of genetic susceptibility to breast cancer
-
Antoniou AC, Easton DF (2006) Models of genetic susceptibility to breast cancer. Oncogene 25:5898–5905. doi: 10.1038/sj.onc.1209879
-
(2006)
Oncogene
, vol.25
, pp. 5898-5905
-
-
Antoniou, A.C.1
Easton, D.F.2
-
4
-
-
84884559633
-
Molecular and cellular heterogeneity in breast cancer: Challenges for personalized medicine
-
Rivenbark AG, O’Connor SM, Coleman WB (2013) Molecular and cellular heterogeneity in breast cancer: challenges for personalized medicine. Am J Pathol 183:1113–1124. doi: 10.1016/j.ajpath.2013.08.002.
-
(2013)
Am J Pathol
, vol.183
, pp. 1113-1124
-
-
Rivenbark, A.G.1
O’connor, S.M.2
Coleman, W.B.3
-
5
-
-
0027498979
-
Increasing incidence of breast cancer in family with BRCA1 mutation
-
Narod S, Lynch H, Conway T, Watson P, Feunteun J, Lenoir G (1993) Increasing incidence of breast cancer in family with BRCA1 mutation. Lancet 341:1101–1102
-
(1993)
Lancet
, vol.341
, pp. 1101-1102
-
-
Narod, S.1
Lynch, H.2
Conway, T.3
Watson, P.4
Feunteun, J.5
Lenoir, G.6
-
6
-
-
0037379520
-
Epigenetic inactivation of the Ras-association domain family 1 (RASSF1A) gene and its function in human carcinogenesis
-
Dammann R, Schagdarsurengin U, Strunnikova M, Rastetter M, Seidel C, Liu L, Tommasi S, Pfeifer GP (2003) Epigenetic inactivation of the Ras-association domain family 1 (RASSF1A) gene and its function in human carcinogenesis. Histol Histopathol 18:665–677
-
(2003)
Histol Histopathol
, vol.18
, pp. 665-677
-
-
Dammann, R.1
Schagdarsurengin, U.2
Strunnikova, M.3
Rastetter, M.4
Seidel, C.5
Liu, L.6
Tommasi, S.7
Pfeifer, G.P.8
-
7
-
-
0037310198
-
Hypomethylation of the synuclein gamma gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma
-
Gupta A, Godwin AK, Vanderveer L, Lu A, Liu J (2003) Hypomethylation of the synuclein gamma gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma. Cancer Res 63:664–673
-
(2003)
Cancer Res
, vol.63
, pp. 664-673
-
-
Gupta, A.1
Godwin, A.K.2
Vanderveer, L.3
Lu, A.4
Liu, J.5
-
9
-
-
78049308800
-
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
-
Prat A, Parker JS, Karginova O, Fan C, Livasy C, Herschkowitz JI, He X, Perou CM (2010) Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer. Breast Cancer Res 12:R68. doi: 10.1186/bcr2635
-
(2010)
Breast Cancer Res
, vol.12
, pp. R68
-
-
Prat, A.1
Parker, J.S.2
Karginova, O.3
Fan, C.4
Livasy, C.5
Herschkowitz, J.I.6
He, X.7
Perou, C.M.8
-
10
-
-
79960100823
-
Therapeutically activating RB: Reestablishing cell cycle control in endocrine therapy-resistant breast cancer
-
Thangavel C, Dean JL, Ertel A, Knudsen KE, Aldaz CM, Witkiewicz AK, Clarke R, Knudsen ES (2011) Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer. Endocr Relat Cancer 18:333–345. doi: 10.1530/ERC-10-0262
-
(2011)
Endocr Relat Cancer
, vol.18
, pp. 333-345
-
-
Thangavel, C.1
Dean, J.L.2
Ertel, A.3
Knudsen, K.E.4
Aldaz, C.M.5
Witkiewicz, A.K.6
Clarke, R.7
Knudsen, E.S.8
-
11
-
-
0035878753
-
High tumor levels of vascular endothelial growth factor predict poor response to systemic therapy in advanced breast cancer
-
Foekens JA, Peters HA, Grebenchtchikov N, Look MP, Meijer-van Gelder ME, Geurts- Moespot A, van der Kwast TH, Sweep CG, Klijn JG (2001) High tumor levels of vascular endothelial growth factor predict poor response to systemic therapy in advanced breast cancer. Cancer Res 61:5407–5414
-
(2001)
Cancer Res
, vol.61
, pp. 5407-5414
-
-
Foekens, J.A.1
Peters, H.A.2
Grebenchtchikov, N.3
Look, M.P.4
Meijer-Van Gelder, M.E.5
Geurts- Moespot, A.6
Van Der Kwast, T.H.7
Sweep, C.G.8
Klijn, J.G.9
-
12
-
-
77149122714
-
Epigenetic regulation in estrogen receptor positive breast cancer—role in treatment response
-
Pathiraja TN, Stearns V, Oesterreich S (2010) Epigenetic regulation in estrogen receptor positive breast cancer—role in treatment response. J Mammary Gland Biol Neoplasia 15:35–47. doi: 10.1007/s10911-010-9166-0
-
(2010)
J Mammary Gland Biol Neoplasia
, vol.15
, pp. 35-47
-
-
Pathiraja, T.N.1
Stearns, V.2
Oesterreich, S.3
-
13
-
-
33745685866
-
Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: Tamoxifen-bound reactivated ER recruits distinctive corepressor complexes
-
Sharma D, Saxena NK, Davidson NE, Vertino PM (2006) Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes. Cancer Res 66:6370–6378. doi: 10.1158/0008-5472.CAN-06-0402
-
(2006)
Cancer Res
, vol.66
, pp. 6370-6378
-
-
Sharma, D.1
Saxena, N.K.2
Davidson, N.E.3
Vertino, P.M.4
-
14
-
-
65249157050
-
Epigenetics, DNA methylation, and chromatin modifying drugs
-
Szyf M (2009) Epigenetics, DNA methylation, and chromatin modifying drugs. Annu Rev Pharmacol Toxicol 49:243–263. doi: 10.1146/annurev-pharmtox-061008-103102
-
(2009)
Annu Rev Pharmacol Toxicol
, vol.49
, pp. 243-263
-
-
Szyf, M.1
-
15
-
-
33746679765
-
Effect of histone deacetylase inhibitor LAQ824 on antineoplastic action of 5-Aza-2’-deoxycytidine (Decitabine) on human breast carcinoma cells
-
Hurtubise A, Momparler RL (2006) Effect of histone deacetylase inhibitor LAQ824 on antineoplastic action of 5-Aza-2’-deoxycytidine (decitabine) on human breast carcinoma cells. Cancer Chemother Pharmacol 58:618–625. doi: 10.1007/s00280-006-0225-6
-
(2006)
Cancer Chemother Pharmacol
, vol.58
, pp. 618-625
-
-
Hurtubise, A.1
Momparler, R.L.2
-
16
-
-
0034917318
-
Antineoplastic action of 5-aza-2’-deoxycytidineand histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells
-
Bovenzi V, Momparler RL (2001) Antineoplastic action of 5-aza-2’-deoxycytidineand histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells. Cancer Chemother Pharmacol 48:71–76
-
(2001)
Cancer Chemother Pharmacol
, vol.48
, pp. 71-76
-
-
Bovenzi, V.1
Momparler, R.L.2
-
17
-
-
77951236061
-
Epigenetic repression of PDZ-LIM domain-containing protein 2 implications for the biology and treatment of breast cancer
-
Qu Z, Fu J, Yan P, Hu J, Cheng S-Y, Xiao G (2010) Epigenetic repression of PDZ-LIM domain-containing protein 2 implications for the biology and treatment of breast cancer. J Biol Chem 285:11786–11792. doi: 10.1074/jbc.M109.086561
-
(2010)
J Biol Chem
, vol.285
, pp. 11786-11792
-
-
Qu, Z.1
Fu, J.2
Yan, P.3
Hu, J.4
Cheng, S.-Y.5
Xiao, G.6
-
18
-
-
77956945027
-
Reactivation of epigenetically silenced HER4/ERBB4 results in apoptosis of breast tumor cells
-
Das PM, Thor AD, Edgerton SM, Barry SK, Chen DF, Jones FE (2010) Reactivation of epigenetically silenced HER4/ERBB4 results in apoptosis of breast tumor cells. Oncogene 29:5214–5219. doi: 10.1038/onc.2010.271
-
(2010)
Oncogene
, vol.29
, pp. 5214-5219
-
-
Das, P.M.1
Thor, A.D.2
Edgerton, S.M.3
Barry, S.K.4
Chen, D.F.5
Jones, F.E.6
-
19
-
-
84876411649
-
DACT1, an antagonist to Wnt/β-catenin signaling, suppresses tumor cell growth and is frequently silenced in breast cancer
-
Yin X, Xiang T, Li L, Su X, Shu X, Luo X, Huang J, Yuan Y, Peng W, Oberst M, Kelly K, Ren G, Tao Q (2013) DACT1, an antagonist to Wnt/β-catenin signaling, suppresses tumor cell growth and is frequently silenced in breast cancer. Breast Cancer Res 15:R23. doi: 10.1186/bcr3399
-
(2013)
Breast Cancer Res
, vol.15
, pp. R23
-
-
Yin, X.1
Xiang, T.2
Li, L.3
Su, X.4
Shu, X.5
Luo, X.6
Huang, J.7
Yuan, Y.8
Peng, W.9
Oberst, M.10
Kelly, K.11
Ren, G.12
Tao, Q.13
-
20
-
-
84884919327
-
Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis
-
Borges S, Döppler H, Perez EA, Andorfer CA, Sun Z, Anastasiadis PZ, Thompson EA, Geiger XJ, Storz P (2013) Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis. Breast Cancer Res 15:R66. doi: 10.1186/bcr3460
-
(2013)
Breast Cancer Res
, vol.15
, pp. R66
-
-
Borges, S.1
Döppler, H.2
Perez, E.A.3
Orfer, C.A.4
Sun, Z.5
Anastasiadis, P.Z.6
Thompson, E.A.7
Geiger, X.J.8
Storz, P.9
-
21
-
-
40149092689
-
Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo
-
Ateeq B, Unterberger A, Szyf M, Rabbani SA (2008) Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo. Neoplasia 10:266–278
-
(2008)
Neoplasia
, vol.10
, pp. 266-278
-
-
Ateeq, B.1
Unterberger, A.2
Szyf, M.3
Rabbani, S.A.4
-
22
-
-
84855354318
-
DNA demethylation by 5-aza-2- deoxycytidine treatment abrogates 17 beta-estradiolinduced cell growth and restores expression of DNA repair genes in human breast cancer cells
-
Singh KP, Treas J, Tyagi T, Gao W (2012) DNA demethylation by 5-aza-2- deoxycytidine treatment abrogates 17 beta-estradiolinduced cell growth and restores expression of DNA repair genes in human breast cancer cells. Cancer Lett 316:62–69. doi: 10.1016/j.canlet.2011.10.022
-
(2012)
Cancer Lett
, vol.316
, pp. 62-69
-
-
Singh, K.P.1
Treas, J.2
Tyagi, T.3
Gao, W.4
-
23
-
-
84879741034
-
Methylation of the claudin 1 promoter is associated with loss of expression in estrogen receptor positive breast cancer
-
Di Cello F, Cope L, Li H, Jeschke J, Wang W, Baylin SB, Zahnow CA (2013) Methylation of the claudin 1 promoter is associated with loss of expression in estrogen receptor positive breast cancer. PLoS ONE 8:e68630. doi: 10.1371/journal.pone.0068630
-
(2013)
Plos ONE
, vol.8
, pp. e68630
-
-
Di Cello, F.1
Cope, L.2
Li, H.3
Jeschke, J.4
Wang, W.5
Baylin, S.B.6
Zahnow, C.A.7
-
24
-
-
84880709210
-
Insulin-like growth factor binding protein-3 (IGFBP-3) plays a role in the anti-tumorigenic effects of 5-Aza-2′-deoxycytidine (AZA) in breast cancer cells
-
Zeng L, Jarrett C, Brown K, Gillespie KM, Holly JMP, Perks CM (2013) Insulin-like growth factor binding protein-3 (IGFBP-3) plays a role in the anti-tumorigenic effects of 5-Aza-2′-deoxycytidine (AZA) in breast cancer cells. Exp Cell Res 319:2282–2295. doi: 10.1016/j.yexcr.2013.06.011
-
(2013)
Exp Cell Res
, vol.319
, pp. 2282-2295
-
-
Zeng, L.1
Jarrett, C.2
Brown, K.3
Gillespie, K.M.4
Holly, J.5
Perks, C.M.6
-
25
-
-
0035477320
-
Synergistic activation of functional estrogen receptor (ER)-α by DNA methyltransferase and histone deacetylase inhibition in human ER-α-negative breast cancer cells
-
Yang X, Phillips DL, Ferguson AT, Nelson WG, Herman JG, Davidson NE (2001) Synergistic activation of functional estrogen receptor (ER)-α by DNA methyltransferase and histone deacetylase inhibition in human ER-α-negative breast cancer cells. Cancer Res 61:7025–7029
-
(2001)
Cancer Res
, vol.61
, pp. 7025-7029
-
-
Yang, X.1
Phillips, D.L.2
Ferguson, A.T.3
Nelson, W.G.4
Herman, J.G.5
Davidson, N.E.6
-
26
-
-
83055194490
-
Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline- based chemotherapy and the demethylating agent decitabine
-
Ari F, Napieralski R, Ulukaya E, Dere E, Colling C, Honert K, Krüger A, Kiechle M, Schmitt M (2011) Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline- based chemotherapy and the demethylating agent decitabine. Cell Biochem Funct 29:651–659. doi: 10.1002/cbf.1801
-
(2011)
Cell Biochem Funct
, vol.29
, pp. 651-659
-
-
Ari, F.1
Napieralski, R.2
Ulukaya, E.3
Dere, E.4
Colling, C.5
Honert, K.6
Krüger, A.7
Kiechle, M.8
Schmitt, M.9
-
27
-
-
47549097004
-
Trichostatin A and 5 Aza-2′ deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR
-
Pryzbylkowski P, Obajimi O, Keen JC (2008) Trichostatin A and 5 Aza-2′ deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR. Breast Cancer Res Treat 111:15–25. doi: 10.1007/s10549-007-9751-0
-
(2008)
Breast Cancer Res Treat
, vol.111
, pp. 15-25
-
-
Pryzbylkowski, P.1
Obajimi, O.2
Keen, J.C.3
-
28
-
-
77953608981
-
Long-term genistein treatment of MCF-7 cells decreases acetylated histone 3 expression and alters growth responses to mitogens and histone deacetylase inhibitors
-
Jawaid K, Crane SR, Nowers JL, Lacey M, Whitehead SA (2010) Long-term genistein treatment of MCF-7 cells decreases acetylated histone 3 expression and alters growth responses to mitogens and histone deacetylase inhibitors. J Steroid Biochem Mol Biol 120:164–171. doi: 10.1016/j.jsbmb.2010.04.007
-
(2010)
J Steroid Biochem Mol Biol
, vol.120
, pp. 164-171
-
-
Jawaid, K.1
Crane, S.R.2
Nowers, J.L.3
Lacey, M.4
Whitehead, S.A.5
-
29
-
-
84856230176
-
Enhancement of chemotherapeutic effi cacy in hypermethylator breast cancer cells through targeted and pharmacologic inhibition of DNMT3b
-
Sandhu R, Rivenbark AG, Coleman WB (2012) Enhancement of chemotherapeutic effi cacy in hypermethylator breast cancer cells through targeted and pharmacologic inhibition of DNMT3b. Breast Cancer Res Treat 131:3 85–399. doi: 10.1007/s10549-011-1409-2
-
(2012)
Breast Cancer Res Treat
, vol.131
, Issue.3
, pp. 85-399
-
-
Sandhu, R.1
Rivenbark, A.G.2
Coleman, W.B.3
-
30
-
-
77955853899
-
Demethylating agent 5-aza-2- deoxycytidine enhances susceptibility of breast cancer cells to anticancer agents
-
Mirza S, Sharma G, Pandya P, Ralhan R (2010) Demethylating agent 5-aza-2- deoxycytidine enhances susceptibility of breast cancer cells to anticancer agents. Mol Cell Biochem 342:101–109. doi: 10.1007/s11010-010-0473-y
-
(2010)
Mol Cell Biochem
, vol.342
, pp. 101-109
-
-
Mirza, S.1
Sharma, G.2
Pandya, P.3
Ralhan, R.4
-
31
-
-
84865988286
-
Epigenetic modulation of the biophysical properties of drug-resistant cell lipids to restore drug transport and endocytic functions
-
Vijayaraghavalu S, Peetla C, Lu S, Labhasetwar V (2012) Epigenetic modulation of the biophysical properties of drug-resistant cell lipids to restore drug transport and endocytic functions. Mol Pharm 9:2730–2742. doi: 10.1021/mp300281t
-
(2012)
Mol Pharm
, vol.9
, pp. 2730-2742
-
-
Vijayaraghavalu, S.1
Peetla, C.2
Lu, S.3
Labhasetwar, V.4
-
32
-
-
84872146371
-
Highly synergistic effect of sequential treatment with epigenetic and anticancer drugs to overcome drug resistance in breast cancer cells is mediated via activation of p21 gene expression leading to G2/M cycle arrest
-
Vijayaraghavalu S, Dermawan JK, Cheriyath V, Labhasetwar V (2013) Highly synergistic effect of sequential treatment with epigenetic and anticancer drugs to overcome drug resistance in breast cancer cells is mediated via activation of p21 gene expression leading to G2/M cycle arrest. Mol Pharm 10:337–352. doi: 10.1021/mp3004622
-
(2013)
Mol Pharm
, vol.10
, pp. 337-352
-
-
Vijayaraghavalu, S.1
Dermawan, J.K.2
Cheriyath, V.3
Labhasetwar, V.4
-
33
-
-
84874215066
-
Regulation of human Cripto-1 expression by nuclear receptors and DNA promoter methylation in human embryonal and breast cancer cells
-
Bianco C, Castro NP, Baraty C, Rollman K, Held N, Rangel MC, Karasawa H, Gonzales M, Strizzi L, Salomon DS (2013) Regulation of human Cripto-1 expression by nuclear receptors and DNA promoter methylation in human embryonal and breast cancer cells. J Cell Physiol 228:1174–1188. doi: 10.1002/jcp.24271
-
(2013)
J Cell Physiol
, vol.228
, pp. 1174-1188
-
-
Bianco, C.1
Castro, N.P.2
Baraty, C.3
Rollman, K.4
Held, N.5
Rangel, M.C.6
Karasawa, H.7
Gonzales, M.8
Strizzi, L.9
Salomon, D.S.10
-
34
-
-
84863694083
-
Tamoxifen-induced epigenetic silencing of oestrogen-regulated genes in anti-hormone resistant breast cancer
-
Stone A, Valdés-Mora F, Gee JMW, Farrow L, McClelland RA, Fiegl H, Dutkowski C, McCloy RA, Sutherland RL, Musgrove EA, Nicholson RI (2012) Tamoxifen-induced epigenetic silencing of oestrogen-regulated genes in anti-hormone resistant breast cancer. PLoS ONE 7:e40466. doi: 10.1371/journal.pone.0040466
-
(2012)
Plos ONE
, vol.7
, pp. e40466
-
-
Stone, A.1
Valdés-Mora, F.2
Gee, J.3
Farrow, L.4
McClelland, R.A.5
Fiegl, H.6
Dutkowski, C.7
McCloy, R.A.8
Sutherland, R.L.9
Musgrove, E.A.10
Nicholson, R.I.11
-
35
-
-
84865165269
-
ING1 and 5-azacytidine act synergistically to block breast cancer cell growth
-
Thakur S, Feng X, Qiao Shi Z, Ganapathy A, Kumar Mishra M, Atadja P, Morris D, Riabowol K (2012) ING1 and 5-azacytidine act synergistically to block breast cancer cell growth. PLoS One 7:e43671. doi: 10.1371/journal.pone.0043671
-
(2012)
Plos One
, vol.7
, pp. e43671
-
-
Thakur, S.1
Feng, X.2
Qiao Shi, Z.3
Ganapathy, A.4
Kumar Mishra, M.5
Atadja, P.6
Morris, D.7
Riabowol, K.8
-
36
-
-
70449713327
-
5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats
-
Tikoo K, Ali IY, Gupta J, Gupta C (2009) 5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats. Toxicol Lett 191:158–166. doi: 10.1016/j.toxlet.2009.08.018
-
(2009)
Toxicol Lett
, vol.191
, pp. 158-166
-
-
Tikoo, K.1
Ali, I.Y.2
Gupta, J.3
Gupta, C.4
-
37
-
-
84921766276
-
-
NCT 00030615. Decitabine in treating patients with advanced solid tumors
-
Weber J (2002) NCT 00030615. Decitabine in treating patients with advanced solid tumors. https://clinicaltrials.gov
-
(2002)
-
-
Weber, J.1
-
38
-
-
0344990164
-
Phase I trial of continuous infusion 5-aza-2’-deoxycytidine
-
Aparicio A, Eads CA, Leong LA, Laird PW, Newman EM, Synold TW, Baker SD, Zhao M, Weber JS (2003) Phase I trial of continuous infusion 5-aza-2’-deoxycytidine. Cancer Chemother Pharmacol 51:231–239. doi: 10.1007/s00280-002-0563-y
-
(2003)
Cancer Chemother Pharmacol
, vol.51
, pp. 231-239
-
-
Aparicio, A.1
Eads, C.A.2
Leong, L.A.3
Laird, P.W.4
Newman, E.M.5
Synold, T.W.6
Baker, S.D.7
Zhao, M.8
Weber, J.S.9
-
39
-
-
34548414620
-
Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors
-
Appleton K, Mackay HJ, Judson I, Plumb JA, McCormick C, Strathdee G, Lee C, Barrett S, Reade S, Jadayel D, Tang A, Bellenger K, Mackay L, Setanoians A, Schätzlein A, Twelves C, Kaye SB, Brown R (2007) Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors. J Clin Oncol Off J Am Soc Clin Oncol 25:4603–4609. doi: 10.1200/JCO.2007.10.8688
-
(2007)
J Clin Oncol off J am Soc Clin Oncol
, vol.25
, pp. 4603-4609
-
-
Appleton, K.1
Mackay, H.J.2
Judson, I.3
Plumb, J.A.4
McCormick, C.5
Strathdee, G.6
Lee, C.7
Barrett, S.8
Reade, S.9
Jadayel, D.10
Tang, A.11
Bellenger, K.12
Mackay, L.13
Setanoians, A.14
Schätzlein, A.15
Twelves, C.16
Kaye, S.B.17
Brown, R.18
-
40
-
-
84921744752
-
-
NCT 00748553. A phase I/II clinical trial of vidaza with abraxane in the treatment of patients with advanced or metastatic solid tumors and breast cancer (VA)
-
Khong HT (2008) NCT 00748553. A phase I/II clinical trial of vidaza with abraxane in the treatment of patients with advanced or metastatic solid tumors and breast cancer (VA). https://clinicaltrials.gov
-
(2008)
-
-
Khong, H.T.1
-
41
-
-
33947153008
-
Multiple histone deacetylases repress tumor suppressor gene ARHI in breast cancer
-
Feng W, Lu Z, Luo RZ, Zhang X, Seto E, Liao WS-L, Yu Y (2007) Multiple histone deacetylases repress tumor suppressor gene ARHI in breast cancer. Int J Cancer 120:1664–1668. doi: 10.1002/ijc.22474
-
(2007)
Int J Cancer
, vol.120
, pp. 1664-1668
-
-
Feng, W.1
Lu, Z.2
Luo, R.Z.3
Zhang, X.4
Seto, E.5
Liao, W.-L.6
Yu, Y.7
-
42
-
-
38849139136
-
TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases
-
Yarosh W, Barrientos T, Esmailpour T, Lin L, Carpenter PM, Osann K, Anton-Culver H, Huang T (2008) TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases. Cancer Res 68:693–699. doi: 10.1158/0008-5472.CAN-07-5012
-
(2008)
Cancer Res
, vol.68
, pp. 693-699
-
-
Yarosh, W.1
Barrientos, T.2
Esmailpour, T.3
Lin, L.4
Carpenter, P.M.5
Osann, K.6
Anton-Culver, H.7
Huang, T.8
-
43
-
-
78751475720
-
Cytoplasmic compartmentalization of SOX9 abrogates the growth arrest response of breast cancer cells that can be rescued by trichostatin A treatment
-
Chakravarty G, Rider B, Mondal D (2011) Cytoplasmic compartmentalization of SOX9 abrogates the growth arrest response of breast cancer cells that can be rescued by trichostatin A treatment. Cancer Biol Ther 11:71–83. doi: 10.4161/cbt.11.1.13952
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 71-83
-
-
Chakravarty, G.1
Rider, B.2
Mondal, D.3
-
44
-
-
77956627130
-
Trichostatin A enhances acetylation as well as protein stability of ERalpha through induction of p300 protein
-
Kim S-H, Kang H-J, Na H, Lee M-O (2010) Trichostatin A enhances acetylation as well as protein stability of ERalpha through induction of p300 protein. Breast Cancer Res 12:R22. doi: 10.1186/bcr2562
-
(2010)
Breast Cancer Res
, vol.12
, pp. R22
-
-
Kim, S.-H.1
Kang, H.-J.2
Na, H.3
Lee, M.-O.4
-
45
-
-
23744495968
-
Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor alpha, in response to deacetylase inhibition by valproic acid and trichostatin A
-
Reid G, Métivier R, Lin C-Y, Denger S, Ibberson D, Ivacevic T, Brand H, Benes V, Liu ET, Gannon F (2005) Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor alpha, in response to deacetylase inhibition by valproic acid and trichostatin A. Oncogene 24:4894–4907. doi: 10.1038/sj.onc.1208662
-
(2005)
Oncogene
, vol.24
, pp. 4894-4907
-
-
Reid, G.1
Métivier, R.2
Lin, C.-Y.3
Denger, S.4
Ibberson, D.5
Ivacevic, T.6
Brand, H.7
Benes, V.8
Liu, E.T.9
Gannon, F.10
-
46
-
-
1642339046
-
The histone deacetylase inhibitor trichostatin A sensitizes estrogen receptor α-negative breast cancer cells to tamoxifen
-
Jang ER, Lim S-J, Lee ES, Jeong G, Kim T-Y, Bang Y-J, Lee J-S (2003) The histone deacetylase inhibitor trichostatin A sensitizes estrogen receptor α-negative breast cancer cells to tamoxifen. Oncogene 23:1724–1736. doi: 10.1038/sj.onc.1207315
-
(2003)
Oncogene
, vol.23
, pp. 1724-1736
-
-
Jang, E.R.1
Lim, S.-J.2
Lee, E.S.3
Jeong, G.4
Kim, T.-Y.5
Bang, Y.-J.6
Lee, J.-S.7
-
47
-
-
84855283939
-
The histone deacetylase inhibitor trichostatin A alters microRNA expression profi les in apoptosis-resistant breast cancer cells
-
Collins-Burow B (2011) The histone deacetylase inhibitor trichostatin A alters microRNA expression profi les in apoptosis-resistant breast cancer cells. Oncol Rep. doi: 10.3892/or.2011.1488
-
(2011)
Oncol Rep
-
-
Collins-Burow, B.1
-
48
-
-
84862006182
-
The enhanced antiproliferative response to combined treatment of trichostatin A with raloxifene in MCF-7 breast cancer cells and its relevance to estrogen receptor β expression
-
Tu Z, Li H, Ma Y, Tang B, Tian J, Akers W, Achilefu S, Gu Y (2012) The enhanced antiproliferative response to combined treatment of trichostatin A with raloxifene in MCF-7 breast cancer cells and its relevance to estrogen receptor β expression. Mol Cell Biochem 366: 111–122. doi: 10.1007/s11010-012-1288-9
-
(2012)
Mol Cell Biochem
, vol.366
, pp. 111-122
-
-
Tu, Z.1
Li, H.2
Ma, Y.3
Tang, B.4
Tian, J.5
Akers, W.6
Achilefu, S.7
Gu, Y.8
-
49
-
-
84880509091
-
Reversal of ER-β silencing by chromatin modifying agents overrides acquired tamoxifen resistance
-
Pitta CA, Papageorgis P, Charalambous C, Constantinou AI (2013) Reversal of ER-β silencing by chromatin modifying agents overrides acquired tamoxifen resistance. Cancer Lett 337:167–176. doi: 10.1016/j.canlet.2013.05.031
-
(2013)
Cancer Lett
, vol.337
, pp. 167-176
-
-
Pitta, C.A.1
Papageorgis, P.2
Charalambous, C.3
Constantinou, A.I.4
-
50
-
-
59349106138
-
Timing is everything: Order of administration of 5-aza 2′ deoxycytidine, trichostatin A and tamoxifen changes estrogen receptor mRNA expression and cell sensitivity
-
Hostetter CL, Licata LA, Keen JC (2009) Timing is everything: Order of administration of 5-aza 2′ deoxycytidine, trichostatin A and tamoxifen changes estrogen receptor mRNA expression and cell sensitivity. Cancer Lett 275:178–184. doi: 10.1016/j.canlet.2008.10.005
-
(2009)
Cancer Lett
, vol.275
, pp. 178-184
-
-
Hostetter, C.L.1
Licata, L.A.2
Keen, J.C.3
-
51
-
-
44749085668
-
ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor
-
Fan J, Yin W-J, Lu J-S, Wang L, Wu J, Wu F-Y, Di G-H, Shen Z-Z, Shao Z-M (2008) ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor. J Cancer Res ClinOncol 134:883–890. doi: 10.1007/s00432-008-0354-x
-
(2008)
J Cancer Res Clinoncol
, vol.134
, pp. 883-890
-
-
Fan, J.1
Yin, W.-J.2
Lu, J.-S.3
Wang, L.4
Wu, J.5
Wu, F.-Y.6
Di, G.-H.7
Shen, Z.-Z.8
Shao, Z.-M.9
-
52
-
-
84872779585
-
Inhibition of lymphangiogenic factor VEGF-C expression and production by the histone deacetylase inhibitor suberoylanilide hydroxamic acid in breast cancer cells
-
Hung W-C (2012) Inhibition of lymphangiogenic factor VEGF-C expression and production by the histone deacetylase inhibitor suberoylanilide hydroxamic acid in breast cancer cells. Oncol Rep. doi: 10.3892/or.2012.2188
-
(2012)
Oncol Rep
-
-
Hung, W.-C.1
-
53
-
-
84885414197
-
Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, enhances radiosensitivity and suppresses lung metastasis in breast cancer in vitro and in vivo
-
Chiu H-W, Yeh Y-L, Wang Y-C, Huang W-J, Chen Y-A, Chiou Y-S, Ho S-Y, Lin P, Wang Y-J (2013) Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, enhances radiosensitivity and suppresses lung metastasis in breast cancer in vitro and in vivo. PLoS ONE 8:e76340. doi: 10.1371/journal.pone.0076340
-
(2013)
Plos ONE
, vol.8
, pp. e76340
-
-
Chiu, H.-W.1
Yeh, Y.-L.2
Wang, Y.-C.3
Huang, W.-J.4
Chen, Y.-A.5
Chiou, Y.-S.6
Ho, S.-Y.7
Lin, P.8
Wang, Y.-J.9
-
54
-
-
81755171451
-
MiR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells
-
Eades G, Yang M, Yao Y, Zhang Y, Zhou Q (2011) miR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells. J Biol Chem 286:40725–40733. doi: 10.1074/jbc.M111.275495
-
(2011)
J Biol Chem
, vol.286
, pp. 40725-40733
-
-
Eades, G.1
Yang, M.2
Yao, Y.3
Zhang, Y.4
Zhou, Q.5
-
55
-
-
84866523199
-
SAHA/Vorinostat induces the expression of the CD137 receptor/ligand system and enhances apoptosis mediated by soluble CD137 receptor in a human breast cancer cell line
-
Bellarosa D, Bressan A, Bigioni M, Parlani M, Maggi CA, Binaschi M (2012) SAHA/Vorinostat induces the expression of the CD137 receptor/ligand system and enhances apoptosis mediated by soluble CD137 receptor in a human breast cancer cell line. Int J Oncol 41:1486–1494. doi: 10.3892/ijo.2012.1551
-
(2012)
Int J Oncol
, vol.41
, pp. 1486-1494
-
-
Bellarosa, D.1
Bressan, A.2
Bigioni, M.3
Parlani, M.4
Maggi, C.A.5
Binaschi, M.6
-
56
-
-
84874812625
-
Drug resistant breast cancer cell line displays cancer stem cell phenotype and responds sensitively to epigenetic drug SAHA
-
Lu S, Labhasetwar V (2013) Drug resistant breast cancer cell line displays cancer stem cell phenotype and responds sensitively to epigenetic drug SAHA. Drug Deliv Transl Res 3: 183–194. doi: 10.1007/s13346-012-0113-z
-
(2013)
Drug Deliv Transl Res
, vol.3
, pp. 183-194
-
-
Lu, S.1
Labhasetwar, V.2
-
57
-
-
84861961464
-
Combination of pan-histone deacetylase inhibitor and autophagy inhibitor exerts superior efficacy against triple-negative human breast cancer cells
-
Rao R, Balusu R, Fiskus W, Mudunuru U, Venkannagari S, Chauhan L, Smith JE, Hembruff SL, Ha K, Atadja P, Bhalla KN (2012) Combination of pan-histone deacetylase inhibitor and autophagy inhibitor exerts superior efficacy against triple-negative human breast cancer cells. Mol Cancer Ther 11:973–983. doi: 10.1158/1535-7163.MCT-11-0979
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 973-983
-
-
Rao, R.1
Balusu, R.2
Fiskus, W.3
Mudunuru, U.4
Venkannagari, S.5
Chauhan, L.6
Smith, J.E.7
Hembruff, S.L.8
Ha, K.9
Atadja, P.10
Bhalla, K.N.11
-
58
-
-
84856230241
-
Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells
-
Huang Y, Vasilatos SN, Boric L, Shaw PG, Davidson NE (2012) Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells. Breast Cancer Res Treat 131:777–789. doi: 10.1007/s10549-011-1480-8
-
(2012)
Breast Cancer Res Treat
, vol.131
, pp. 777-789
-
-
Huang, Y.1
Vasilatos, S.N.2
Boric, L.3
Shaw, P.G.4
Davidson, N.E.5
-
59
-
-
84878964098
-
Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells
-
Vasilatos SN, Katz TA, Oesterreich S, Wan Y, Davidson NE, Huang Y (2013) Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells. Carcinogenesis 34:1196–1207. doi: 10.1093/carcin/bgt033
-
(2013)
Carcinogenesis
, vol.34
, pp. 1196-1207
-
-
Vasilatos, S.N.1
Katz, T.A.2
Oesterreich, S.3
Wan, Y.4
Davidson, N.E.5
Huang, Y.6
-
60
-
-
78649330519
-
The pan-DAC inhibitor LBH589 is a multi-functional agent in breast cancer cells: Cytotoxic drug and inducer of sodium-iodide symporter (NIS)
-
Fortunati N, Catalano MG, Marano F, Mugoni V, Pugliese M, Bosco O, Mainini F, Boccuzzi G (2010) The pan-DAC inhibitor LBH589 is a multi-functional agent in breast cancer cells: cytotoxic drug and inducer of sodium-iodide symporter (NIS). Breast Cancer Res Treat 124:667–675. doi: 10.1007/s10549-010-0789-z
-
(2010)
Breast Cancer Res Treat
, vol.124
, pp. 667-675
-
-
Fortunati, N.1
Catalano, M.G.2
Marano, F.3
Mugoni, V.4
Pugliese, M.5
Bosco, O.6
Mainini, F.7
Boccuzzi, G.8
-
61
-
-
84861968080
-
Targeting triple-negative breast cancer cells with the histone deacetylase inhibitor panobinostat
-
Tate CR, Rhodes LV, Segar HC, Driver JL, Pounder FN, Burow ME, Collins-Burow BM (2012) Targeting triple-negative breast cancer cells with the histone deacetylase inhibitor panobinostat. Breast Cancer Res 14:R79. doi: 10.1186/bcr3192
-
(2012)
Breast Cancer Res
, vol.14
, pp. R79
-
-
Tate, C.R.1
Rhodes, L.V.2
Segar, H.C.3
Driver, J.L.4
Pounder, F.N.5
Burow, M.E.6
Collins-Burow, B.M.7
-
62
-
-
77954627516
-
The HDAC inhibitor LBH589 (Panobinostat) is an inhibitory modulator of aromatase gene expression
-
Chen S, Ye J, Kijima I, Evans D (2010) The HDAC inhibitor LBH589 (panobinostat) is an inhibitory modulator of aromatase gene expression. Proc Natl Acad Sci 107:11032– 11037. doi: 10.1073/pnas.1000917107
-
(2010)
Proc Natl Acad Sci 107:11032–
, pp. 11037
-
-
Chen, S.1
Ye, J.2
Kijima, I.3
Evans, D.4
-
63
-
-
84875886681
-
Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells
-
Wang S, Huang J, Lyu H, Lee C-K, Tan J, Wang J, Liu B (2013) Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells. Cell Death Dis 4:e556. doi: 10.1038/cddis.2013.79
-
(2013)
Cell Death Dis
, vol.4
, pp. e556
-
-
Wang, S.1
Huang, J.2
Lyu, H.3
Lee, C.-K.4
Tan, J.5
Wang, J.6
Liu, B.7
-
64
-
-
79957514394
-
HDAC inhibitor SNDX-275 enhances effi cacy of trastuzumab in erbB2- overexpressing breast cancer cells and exhibits potential to overcome trastuzumab resistance
-
Huang X, Wang S, Lee C-K, Yang X, Liu B (2011) HDAC inhibitor SNDX-275 enhances effi cacy of trastuzumab in erbB2- overexpressing breast cancer cells and exhibits potential to overcome trastuzumab resistance. Cancer Lett 307:72–79. doi: 10.1016/j.canlet.2011.03.019
-
(2011)
Cancer Lett
, vol.307
, pp. 72-79
-
-
Huang, X.1
Wang, S.2
Lee, C.-K.3
Yang, X.4
Liu, B.5
-
65
-
-
79952237710
-
Functional activation of the estrogen receptor-α and aromatase by the HDAC inhibitor entinostat sensitizes ER-negative tumors to letrozole
-
Sabnis GJ, Goloubeva O, Chumsri S, Nguyen N, Sukumar S, Brodie AMH (2011) Functional activation of the estrogen receptor-α and aromatase by the HDAC inhibitor entinostat sensitizes ER-negative tumors to letrozole. Cancer Res 71:1893–1903. doi: 10.1158/0008-5472.CAN-10-2458
-
(2011)
Cancer Res
, vol.71
, pp. 1893-1903
-
-
Sabnis, G.J.1
Goloubeva, O.2
Chumsri, S.3
Nguyen, N.4
Sukumar, S.5
Brodie, A.6
-
66
-
-
79958766981
-
Aromatase inhibitors and xenograft studies
-
Chumsri S, Sabnis GJ, Howes T, Brodie AMH (2011) Aromatase inhibitors and xenograft studies. Steroids 76:730–735. doi: 10.1016/j.steroids.2011.02.033
-
(2011)
Steroids
, vol.76
, pp. 730-735
-
-
Chumsri, S.1
Sabnis, G.J.2
Howes, T.3
Brodie, A.4
-
67
-
-
78650443648
-
MS-275 sensitizes TRAIL-resistant breast cancer cells, inhibits angiogenesis and metastasis, and reverses epithelial-mesenchymal transition in vivo
-
Srivastava RK, Kurzrock R, Shankar S (2010) MS-275 sensitizes TRAIL-resistant breast cancer cells, inhibits angiogenesis and metastasis, and reverses epithelial-mesenchymal transition in vivo. Mol Cancer Ther 9: 3254–3266. doi: 10.1158/1535-7163.MCT-10-0582
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 3254-3266
-
-
Srivastava, R.K.1
Kurzrock, R.2
Shankar, S.3
-
68
-
-
1142267455
-
Antiepileptic drugs inhibit cell growth in the human breast cancer cell line MCF 7
-
Olsen CM, Meussen-Elholm ETM, Røste LS, Taubøll E (2004) Antiepileptic drugs inhibit cell growth in the human breast cancer cell line MCF 7. Mol Cell Endocrinol 213: 173–179. doi: 10.1016/j.mce.2003.10.032
-
(2004)
Mol Cell Endocrinol
, vol.213
, pp. 173-179
-
-
Olsen, C.M.1
Meussen-Elholm, E.2
Røste, L.S.3
Taubøll, E.4
-
69
-
-
35348961982
-
Inhibition of histone deacetylase enhances the anti-proliferative action of antiestrogens on breast cancer cellsand blocks tamoxifen-induced proliferation of uterine cells
-
Hodges-Gallagher L, Valentine CD, Bader SE, Kushner PJ (2007) Inhibition of histone deacetylase enhances the anti-proliferative action of antiestrogens on breast cancer cellsand blocks tamoxifen-induced proliferation of uterine cells. Breast Cancer Res Treat 105: 297–309. doi: 10.1007/s10549-006-9459-6
-
(2007)
Breast Cancer Res Treat
, vol.105
, pp. 297-309
-
-
Hodges-Gallagher, L.1
Valentine, C.D.2
Bader, S.E.3
Kushner, P.J.4
-
70
-
-
79952384705
-
Cancer epigenetics reaches mainstream oncology
-
Rodríguez-Paredes M, Esteller M (2011) Cancer epigenetics reaches mainstream oncology. Nat Med 17:330–339. doi: 10.1038/nm.2305
-
(2011)
Nat Med
, vol.17
, pp. 330-339
-
-
Rodríguez-Paredes, M.1
Esteller, M.2
-
71
-
-
50249095068
-
Early phase II trial of oral Vorinostat in relapsed or refractory breast, colorectal, or non-small cell lung cancer
-
Vansteenkiste J, Van Cutsem E, Dumez H, Chen C, Ricker JL, Randolph SS, Schöffski P (2008) Early phase II trial of oral Vorinostat in relapsed or refractory breast, colorectal, or non-small cell lung cancer. Invest New Drugs 26:483–488. doi: 10.1007/s10637-008-9131-6
-
(2008)
Invest New Drugs
, vol.26
, pp. 483-488
-
-
Vansteenkiste, J.1
Van Cutsem, E.2
Dumez, H.3
Chen, C.4
Ricker, J.L.5
Randolph, S.S.6
Schöffski, P.7
-
72
-
-
58149242889
-
A phase II trial of Vorinostat (Suberoylanilide hydroxamic acid) in metastatic breast cancer: A California Cancer Consortium study
-
Luu TH, Morgan RJ, Leong L, Lim D, McNamara M, Portnow J, Frankel P, Smith DD, Doroshow JH, Gandara DR, Aparicio A, Somlo G, Wong C (2008) A phase II trial of Vorinostat (suberoylanilide hydroxamic acid) in metastatic breast cancer: a California Cancer Consortium study. Clin Cancer Res 14: 7138–7142. doi: 10.1158/1078-0432.CCR-08-0122
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7138-7142
-
-
Luu, T.H.1
Morgan, R.J.2
Leong, L.3
Lim, D.4
McNamara, M.5
Portnow, J.6
Frankel, P.7
Smith, D.D.8
Doroshow, J.H.9
Gandara, D.R.10
Aparicio, A.11
Somlo, G.12
Wong, C.13
-
73
-
-
70349682188
-
Phase I trial of vorinostat and doxorubicin in solid tumours: Histone deacetylase 2 expression as a predictive marker
-
Munster PN, Marchion D, Thomas S, Egorin M, Minton S, Springett G, Lee J-H, Simon G, Chiappori A, Sullivan D, Daud A (2009) Phase I trial of vorinostat and doxorubicin in solid tumours: histone deacetylase 2 expression as a predictive marker. Br J Cancer 101: 1044–1050. doi: 10.1038/sj.bjc.6605293
-
(2009)
Br J Cancer
, vol.101
, pp. 1044-1050
-
-
Munster, P.N.1
Marchion, D.2
Thomas, S.3
Egorin, M.4
Minton, S.5
Springett, G.6
Lee, J.-H.7
Simon, G.8
Chiappori, A.9
Sullivan, D.10
Daud, A.11
-
74
-
-
84865168464
-
Phase I–II study of vorinostat plus paclitaxel and bevacizumab in metastatic breast cancer: Evidence for vorinostat- induced tubulin acetylation and Hsp90 inhibition in vivo
-
Ramaswamy B, Fiskus W, Cohen B, Pellegrino C, Hershman DL, Chuang E, Luu T, Somlo G, Goetz M, Swaby R, Shapiro CL, Stearns V, Christos P, Espinoza-Delgado I, Bhalla K, Sparano JA (2011) Phase I–II study of vorinostat plus paclitaxel and bevacizumab in metastatic breast cancer: evidence for vorinostat- induced tubulin acetylation and Hsp90 inhibition in vivo. Breast Cancer Res Treat 132:1063–1072. doi: 10.1007/s10549-011-1928-x
-
(2011)
Breast Cancer Res Treat
, vol.132
, pp. 1063-1072
-
-
Ramaswamy, B.1
Fiskus, W.2
Cohen, B.3
Pellegrino, C.4
Hershman, D.L.5
Chuang, E.6
Luu, T.7
Somlo, G.8
Goetz, M.9
Swaby, R.10
Shapiro, C.L.11
Stearns, V.12
Christos, P.13
Espinoza-Delgado, I.14
Bhalla, K.15
Sparano, J.A.16
-
75
-
-
79958084461
-
A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer
-
Munster PN, Thurn KT, Thomas S, Raha P, Lacevic M, Miller A, Melisko M, Ismail-Khan R, Rugo H, Moasser M, Minton SE (2011) A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer. Br J Cancer 104:1828–1835. doi: 10.1038/bjc.2011.156
-
(2011)
Br J Cancer
, vol.104
, pp. 1828-1835
-
-
Munster, P.N.1
Thurn, K.T.2
Thomas, S.3
Raha, P.4
Lacevic, M.5
Miller, A.6
Melisko, M.7
Ismail-Khan, R.8
Rugo, H.9
Moasser, M.10
Minton, S.E.11
-
76
-
-
79952710830
-
Phase I study of decitabine in combination with vorinostat in patients with advanced solid tumors and non-Hodgkin’s lymphomas
-
Stathis A, Hotte SJ, Chen EX, Hirte HW, Oza AM, Moretto P, Webster S, Laughlin A, Stayner L-A, McGill S, Wang L, Zhang W, Espinoza-Delgado I, Holleran JL, Egorin MJ, Siu LL (2011) Phase I study of decitabine in combination with vorinostat in patients with advanced solid tumors and non-Hodgkin’s lymphomas. Clin Cancer Res 17:1582–1590. doi: 10.1158/1078-0432.CCR-10-1893
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1582-1590
-
-
Stathis, A.1
Hotte, S.J.2
Chen, E.X.3
Hirte, H.W.4
Oza, A.M.5
Moretto, P.6
Webster, S.7
Laughlin, A.8
Stayner, L.-A.9
McGill, S.10
Wang, L.11
Zhang, W.12
Espinoza-Delgado, I.13
Holleran, J.L.14
Egorin, M.J.15
Siu, L.L.16
-
77
-
-
84879834815
-
Randomized phase II, double-blind, placebo-controlled study of exemestane with or without entinostat in postmenopausal women with locally recurrent or metastatic estrogen receptor-positive breast cancer progressing on treatment with a nonsteroidal aromatase inhibitor
-
Yardley DA, Ismail-Khan RR, Melichar B, Lichinitser M, Munster PN, Klein PM, Cruickshank S, Miller KD, Lee MJ, Trepel JB (2013) Randomized phase II, double-blind, placebo-controlled study of exemestane with or without entinostat in postmenopausal women with locally recurrent or metastatic estrogen receptor-positive breast cancer progressing on treatment with a nonsteroidal aromatase inhibitor. J Clin Oncol Off J Am Soc Clin Oncol 31:2128–2135. doi: 10.1200/JCO.2012.43.7251
-
(2013)
J Clin Oncol off J am Soc Clin Oncol
, vol.31
, pp. 2128-2135
-
-
Yardley, D.A.1
Ismail-Khan, R.R.2
Melichar, B.3
Lichinitser, M.4
Munster, P.N.5
Klein, P.M.6
Cruickshank, S.7
Miller, K.D.8
Lee, M.J.9
Trepel, J.B.10
-
78
-
-
84921806786
-
-
NCT 01349959. Azacitidine and entinostat in treating patients with advanced breast cancer
-
Stearns V (2011) NCT 01349959. Azacitidine and entinostat in treating patients with advanced breast cancer. https://clinicaltrials.gov
-
(2011)
-
-
Stearns, V.1
-
79
-
-
84921730745
-
-
NCT 00777335. Study of panobinostat monotherapy in women with v-ERB-B2 avian erythroblastic leukemia viral oncogene homolog 2 (HER2) positive locally recurrent or metastatic breast cancer
-
Finn R (2008) NCT 00777335. Study of panobinostat monotherapy in women with v-ERB-B2 avian erythroblastic leukemia viral oncogene homolog 2 (HER2) positive locally recurrent or metastatic breast cancer. https://clinicaltrials.gov
-
(2008)
-
-
Finn, R.1
-
80
-
-
84866358085
-
A phase I trial of oral administration of panobinostat in combination with paclitaxel and carboplatin in patients with solid tumors
-
Jones SF, Infante JR, Thompson DS, Mohyuddin A, Bendell JC, Yardley DA, Burris HA 3rd (2012) A phase I trial of oral administration of panobinostat in combination with paclitaxel and carboplatin in patients with solid tumors. Cancer Chemother Pharmacol 70:471–475. doi: 10.1007/s00280-012-1931-x
-
(2012)
Cancer Chemother Pharmacol
, vol.70
, pp. 471-475
-
-
Jones, S.F.1
Infante, J.R.2
Thompson, D.S.3
Mohyuddin, A.4
Bendell, J.C.5
Yardley, D.A.6
Burris, H.A.7
-
81
-
-
84921763309
-
-
NCT 01194908. Re-expression of ER in triple negative breast cancers
-
O’Regan R (2010) NCT 01194908. Re-expression of ER in triple negative breast cancers. https://clinicaltrials.gov
-
(2010)
-
-
O’regan, R.1
-
82
-
-
84921822876
-
-
NCT 01010854. Valproic acid in combination with FEC100 for primary therapy in patients with breast cancer (VPA- FEC100
-
Munster P (2009) NCT 01010854. Valproic acid in combination with FEC100 for primary therapy in patients with breast cancer (VPA- FEC100). https://clinicaltrials.gov
-
(2009)
-
-
Munster, P.1
-
83
-
-
34249937594
-
Phase I trial of histone deacetylase inhibition by valproic acid followed by the topoisomerase II inhibitor epirubicin in advanced solid tumors: A clinical and translational study
-
Münster P, Marchion D, Bicaku E, Schmitt M, Lee JH, DeConti R, Simon G, Fishman M, Minton S, Garrett C, Chiappori A, Lush R, Sullivan D, Daud A (2007) Phase I trial of histone deacetylase inhibition by valproic acid followed by the topoisomerase II inhibitor epirubicin in advanced solid tumors: a clinical and translational study. J Clin Oncol Off J Am Soc Clin Oncol 25:1979–1985. doi: 10.1200/JCO.2006.08.6165
-
(2007)
J Clin Oncol off J am Soc Clin Oncol
, vol.25
, pp. 1979-1985
-
-
Münster, P.1
Marchion, D.2
Bicaku, E.3
Schmitt, M.4
Lee, J.H.5
Deconti, R.6
Simon, G.7
Fishman, M.8
Minton, S.9
Garrett, C.10
Chiappori, A.11
Lush, R.12
Sullivan, D.13
Daud, A.14
-
84
-
-
84921795164
-
-
NCT 01171924. A phase Ib expansion study investigating the safety, efficacy, and pharmacokinetics of intravenous CUDC- 101 in subjects with advanced head and neck, gastric, breast, liver and non-small cell lung cancer tumors
-
2010, NCT 01171924. A phase Ib expansion study investigating the safety, efficacy, and pharmacokinetics of intravenous CUDC- 101 in subjects with advanced head and neck, gastric, breast, liver and non-small cell lung cancer tumors. https://clinicaltrials.gov
-
(2010)
-
-
-
85
-
-
77951708371
-
CUDC-101, a multitargeted inhibitor of histone deacetylase, epidermalgrowth factor receptor, and human epidermal growth factor receptor 2, exerts potent anticancer activity
-
Lai C-J, Bao R, Tao X, Wang J, Atoyan R, Qu H, Wang D-G, Yin L, Samson M, Forrester J, Zifcak B, Xu G-X, DellaRocca S, Zhai H-X, Cai X, Munger WE, Keegan M, Pepicelli CV, Qian C (2010) CUDC-101, a multitargeted inhibitor of histone deacetylase, epidermalgrowth factor receptor, and human epidermal growth factor receptor 2, exerts potent anticancer activity. Cancer Res 70:3647–3656. doi: 10.1158/0008-5472.CAN-09-3360
-
(2010)
Cancer Res
, vol.70
, pp. 3647-3656
-
-
Lai, C.-J.1
Bao, R.2
Tao, X.3
Wang, J.4
Atoyan, R.5
Qu, H.6
Wang, D.-G.7
Yin, L.8
Samson, M.9
Forrester, J.10
Zifcak, B.11
Xu, G.-X.12
Dellarocca, S.13
Zhai, H.-X.14
Cai, X.15
Munger, W.E.16
Keegan, M.17
Pepicelli, C.V.18
Qian, C.19
-
86
-
-
73449113904
-
Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation
-
Hervouet E, Vallette FM, Cartron P-F (2009) Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation. Epigenetics 4:487–499
-
(2009)
Epigenetics
, vol.4
, pp. 487-499
-
-
Hervouet, E.1
Vallette, F.M.2
Cartron, P.-F.3
-
87
-
-
84855862393
-
Epigenetic events associated with breast cancer and their prevention by dietary components targeting the epigenome
-
Khan SI, Aumsuwan P, Khan IA, Walker LA, Dasmahapatra AK (2012) Epigenetic events associated with breast cancer and their prevention by dietary components targeting the epigenome. Chem Res Toxicol 25:61–73. doi: 10.1021/tx200378c
-
(2012)
Chem Res Toxicol
, vol.25
, pp. 61-73
-
-
Khan, S.I.1
Aumsuwan, P.2
Khan, I.A.3
Walker, L.A.4
Dasmahapatra, A.K.5
-
88
-
-
84876084653
-
Expression of DNA methyltransferases in breast cancer patients and to analyze the effect of natural compounds on dna methyltransferases and associated proteins
-
Mirza S, Sharma G, Parshad R, Gupta SD, Pandya P, Ralhan R (2013) Expression of DNA methyltransferases in breast cancer patients and to analyze the effect of natural compounds on dna methyltransferases and associated proteins. J Breast Cancer 16:23–31. doi: 10.4048/jbc.2013.16.1.23
-
(2013)
J Breast Cancer
, vol.16
, pp. 23-31
-
-
Mirza, S.1
Sharma, G.2
Parshad, R.3
Gupta, S.D.4
Pandya, P.5
Ralhan, R.6
-
89
-
-
84872843245
-
Curcumin induces cell death and restores tamoxifen sensitivity in the antiestrogen-resistant breast cancer cell lines MCF-7/LCC2 and MCF-7/LCC 9
-
Jiang M, Huang O, Zhang X, Xie Z, Shen A, Liu H, Geng M, Shen K (2013) Curcumin induces cell death and restores tamoxifen sensitivity in the antiestrogen-resistant breast cancer cell lines MCF-7/LCC2 and MCF-7/LCC 9. Molecules 18:701–720. doi: 10.3390/molecules18010701
-
(2013)
Molecules
, vol.18
, pp. 701-720
-
-
Jiang, M.1
Huang, O.2
Zhang, X.3
Xie, Z.4
Shen, A.5
Liu, H.6
Geng, M.7
Shen, K.8
-
90
-
-
84872335358
-
Epigenetic regulation of multiple tumor-related genes leads to suppression of breast tumorigenesis by dietary genistein
-
Li Y, Chen H, Hardy TM, Tollefsbol TO (2013) Epigenetic regulation of multiple tumor-related genes leads to suppression of breast tumorigenesis by dietary genistein. PLoS One 8:e54369. doi: 10.1371/journal.pone.0054369
-
(2013)
Plos One
, vol.8
, pp. e54369
-
-
Li, Y.1
Chen, H.2
Hardy, T.M.3
Tollefsbol, T.O.4
-
91
-
-
84871294130
-
Reactivation of the tumour suppressor RASSF1A in breast cancer by simultaneous targeting of DNA and E2F1 methylation
-
Montenegro MF, Sáez-Ayala M, Piñero- Madrona A, Cabezas-Herrera J, Rodríguez- López JN (2012) Reactivation of the tumour suppressor RASSF1A in breast cancer by simultaneous targeting of DNA and E2F1 methylation. PLoS One 7:e52231. doi: 10.1371/journal.pone.0052231
-
(2012)
Plos One
, vol.7
, pp. e52231
-
-
Montenegro, M.F.1
Sáez-Ayala, M.2
Piñero- Madrona, A.3
Cabezas-Herrera, J.4
Rodríguez- López, J.N.5
-
92
-
-
84867841981
-
MicroRNAs in breast cancer initiation and progression
-
Liu H (2012) MicroRNAs in breast cancer initiation and progression. Cell Mol Life Sci 69:3587–3599. doi: 10.1007/s00018-012-1128-9
-
(2012)
Cell Mol Life Sci
, vol.69
, pp. 3587-3599
-
-
Liu, H.1
-
93
-
-
84860561774
-
Epigenetic reprogramming of cancer cells via targeted DNA methylation
-
Rivenbark AG, Stolzenburg S, Beltran AS, Yuan X, Rots MG, Strahl BD, Blancafort P (2012) Epigenetic reprogramming of cancer cells via targeted DNA methylation. Epigenetics 7:350–360. doi: 10.4161/epi.19507
-
(2012)
Epigenetics
, vol.7
, pp. 350-360
-
-
Rivenbark, A.G.1
Stolzenburg, S.2
Beltran, A.S.3
Yuan, X.4
Rots, M.G.5
Strahl, B.D.6
Blancafort, P.7
-
94
-
-
80052768726
-
Suppression of breast tumor growth and metastasis by an engineered transcription factor
-
Beltran AS, Russo A, Lara H, Fan C, Lizardi PM, Blancafort P (2011) Suppression of breast tumor growth and metastasis by an engineered transcription factor. PLoS ONE 6:e24595. doi: 10.1371/journal.pone.0024595
-
(2011)
Plos ONE
, vol.6
, pp. e24595
-
-
Beltran, A.S.1
Russo, A.2
Lara, H.3
Fan, C.4
Lizardi, P.M.5
Blancafort, P.6
-
95
-
-
84860992007
-
Choosing the right cell line for breast cancer research
-
Holliday DL, Speirs V (2011) Choosing the right cell line for breast cancer research. Breast Cancer Res 13:215. doi: 10.1186/bcr2889
-
(2011)
Breast Cancer Res
, vol.13
, pp. 215
-
-
Holliday, D.L.1
Speirs, V.2
-
96
-
-
33845209913
-
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
-
Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T, Clark L, Bayani N, Coppe J-P, Tong F, Speed T, Spellman PT, DeVries S, Lapuk A, Wang NJ, Kuo W-L, Stilwell JL, Pinkel D, Albertson DG, Waldman FM, McCormick F, Dickson RB, Johnson MD, Lippman M, Ethier S, Gazdar A, Gray JW (2006) A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10:515–527. doi: 10.1016/j.ccr.2006.10.008
-
(2006)
Cancer Cell
, vol.10
, pp. 515-527
-
-
Neve, R.M.1
Chin, K.2
Fridlyand, J.3
Yeh, J.4
Baehner, F.L.5
Fevr, T.6
Clark, L.7
Bayani, N.8
Coppe, J.-P.9
Tong, F.10
Speed, T.11
Spellman, P.T.12
Devries, S.13
Lapuk, A.14
Wang, N.J.15
Kuo, W.-L.16
Stilwell, J.L.17
Pinkel, D.18
Albertson, D.G.19
Waldman, F.M.20
McCormick, F.21
Dickson, R.B.22
Johnson, M.D.23
Lippman, M.24
Ethier, S.25
Gazdar, A.26
Gray, J.W.27
more..
-
97
-
-
30344477367
-
Histone deacetylase inhibitors and the promise of epigenetic (And more) treatments for cancer
-
Minucci S, Pelicci PG (2006) Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. Nat Rev Cancer 6:38–51. doi: 10.1038/nrc1779
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 38-51
-
-
Minucci, S.1
Pelicci, P.G.2
-
98
-
-
84921807604
-
-
NCT 00788931. A trial l of panobinostat given in combination with trastuzumab and paclitaxel in adult female patients with HER2 positive metastatic breast cancer
-
Novartis Pharmaceuticals (2008) NCT 00788931. A trial l of panobinostat given in combination with trastuzumab and paclitaxel in adult female patients with HER2 positive metastatic breast cancer. https://clinicaltrials.gov
-
(2008)
-
-
Pharmaceuticals, N.1
-
99
-
-
84921811825
-
-
NCT 00632489. LBH589 in combination with capecitabine plus/minus (±) lapatinib in breast cancer patients
-
Burris HA (2008) NCT 00632489. LBH589 in combination with capecitabine plus/minus (±) lapatinib in breast cancer patients. https://clinicaltrials.gov
-
(2008)
-
-
Burris, H.A.1
-
100
-
-
84921768163
-
-
NCT 01105312. Panobinostat and letrozole in treating patients with metastatic breast cancer. In: clinicaltrials.org
-
Tan W (2010) NCT 01105312. Panobinostat and letrozole in treating patients with metastatic breast cancer. In: clinicaltrials.org
-
(2010)
-
-
Tan, W.1
-
101
-
-
84921821277
-
-
NCT 00567879. A trial of panobinostat and trastuzumab for adult female patients with HER2 positive metastatic breast cancer whose disease has progressed on or after trastuzumab
-
Pharmaceuticals N (2007) NCT 00567879. A trial of panobinostat and trastuzumab for adult female patients with HER2 positive metastatic breast cancer whose disease has progressed on or after trastuzumab. https://clinicaltrials.gov
-
(2007)
-
-
Pharmaceuticals, N.1
-
102
-
-
84921797237
-
-
NCT 00777049. Study of panobinostat monotherapy in women with HER2 negative locally recurrent or metastatic breast cancer
-
Hurvitz S (2008) NCT 00777049. Study of panobinostat monotherapy in women with HER2 negative locally recurrent or metastatic breast cancer. https://clinicaltrials.gov
-
(2008)
-
-
Hurvitz, S.1
-
103
-
-
84921726352
-
-
NCT 00993642. ERB-B4 after treatment with HDAC inhibitor in ER + tamoxifen refractory breast cancer
-
Collins-Burow B (2009) NCT 00993642. ERB-B4 after treatment with HDAC inhibitor in ER + tamoxifen refractory breast cancer. https://clinicaltrials.gov
-
(2009)
-
-
Collins-Burow, B.1
-
104
-
-
84921755780
-
-
NCT 00020579. MS-275 in treating patients with advanced solid tumors or lymphoma
-
Kummar S (2001) NCT 00020579. MS-275 in treating patients with advanced solid tumors or lymphoma. https://clinicaltrials.gov
-
(2001)
-
-
Kummar, S.1
-
105
-
-
84921774784
-
-
NCT 01434303. Entinostat, lapatinib ditosylate and trastuzumab in patients with locally recurrent or distant relapsed metastatic breast cancer previously treated with trastuzumab only
-
Ueno N (2011) NCT 01434303. Entinostat, lapatinib ditosylate and trastuzumab in patients with locally recurrent or distant relapsed metastatic breast cancer previously treated with trastuzumab only. https://clinicaltrials.gov
-
(2011)
-
-
Ueno, N.1
-
106
-
-
84921756704
-
-
NCT 01594398. Study to assess food effect on pharmacokinetics of entinostat in subjects with breast cancer or non-small cell lung cancer (ENCORE110)
-
McCulloch W (2012) NCT 01594398. Study to assess food effect on pharmacokinetics of entinostat in subjects with breast cancer or non-small cell lung cancer (ENCORE110). https://clinicaltrials.gov
-
(2012)
-
-
McCulloch, W.1
-
107
-
-
84921768087
-
-
NCT 00676663. Study to evaluate exemestane with and without SNDX- 275 in treatment of postmenopausal women with advanced breast cancer (ENCORE301)
-
Yardley D (2008) NCT 00676663. Study to evaluate exemestane with and without SNDX- 275 in treatment of postmenopausal women with advanced breast cancer (ENCORE301). https://clinicaltrials.gov
-
(2008)
-
-
Yardley, D.1
-
108
-
-
84921746795
-
-
NCT 00828854. A phase 2, multicenter study of the effect of the addition of SNDX-275 to continued aromatase inhibitor (AI) therapy in postmenopausal women With ER + breast cancer whose disease is progressing
-
Pharmaceuticals S (2009) NCT 00828854. A phase 2, multicenter study of the effect of the addition of SNDX-275 to continued aromatase inhibitor (AI) therapy in postmenopausal women With ER + breast cancer whose disease is progressing. https://clinicaltrials.gov
-
(2009)
-
-
Pharmaceuticals, S.1
-
109
-
-
84921767900
-
-
NCT 01234532. Entinostat and anastrozole in treating postmenopausal women with triple-negative breast cancer that can be removed by surgery
-
Chumsri S (2010) NCT 01234532. Entinostat and anastrozole in treating postmenopausal women with triple-negative breast cancer that can be removed by surgery. https://clinicaltrials.gov
-
(2010)
-
-
Chumsri, S.1
-
110
-
-
84921756895
-
-
NCT 01720602. Vorinostat in treating patients with stage IV breast cancer receiving hormone therapy
-
Linden H (2012) NCT 01720602. Vorinostat in treating patients with stage IV breast cancer receiving hormone therapy. https://clinicaltrials. gov
-
(2012)
-
-
Linden, H.1
-
111
-
-
84921735615
-
-
NCT 01153672. Vorinostat in treating patients with stage IV breast cancer receiving aromatase inhibitor therapy
-
Linden H (2010) NCT 01153672. Vorinostat in treating patients with stage IV breast cancer receiving aromatase inhibitor therapy. https://clinicaltrials.gov
-
(2010)
-
-
Linden, H.1
-
112
-
-
84921746892
-
-
NCT 01084057. Ixabepilone and vorinostat in treating patients with metastatic breast cancer
-
Luu T (2010) NCT 01084057. Ixabepilone and vorinostat in treating patients with metastatic breast cancer. https://clinicaltrials.gov
-
(2010)
-
-
Luu, T.1
-
113
-
-
84921809065
-
-
NCT00788112. orinostat in treating women with ductal carcinoma in situ of the breast
-
Esserman L (2008) NCT00788112. orinostat in treating women with ductal carcinoma in situ of the breast. https://clinicaltrials.gov
-
(2008)
-
-
Esserman, L.1
-
114
-
-
84921786373
-
-
NCT 00368875. Vorinostat, paclitaxel, and bevacizumab in treating patients with metastatic breast cancer and/or breast cancer that has recurred in the chest wall and cannot be removed by surgery
-
Sparano J (2006) NCT 00368875. Vorinostat, paclitaxel, and bevacizumab in treating patients with metastatic breast cancer and/or breast cancer that has recurred in the chest wall and cannot be removed by surgery. https://clinicaltrials.gov
-
(2006)
-
-
Sparano, J.1
-
115
-
-
84921734935
-
-
NCT 00258349. Vorinostat and trastuzumab in treating patients with metastatic or locally recurrent breast cancer
-
Swaby R (2005) NCT 00258349. Vorinostat and trastuzumab in treating patients with metastatic or locally recurrent breast cancer. https://clinicaltrials.gov
-
(2005)
-
-
Swaby, R.1
-
116
-
-
84921747826
-
-
NCT 00262834. Vorinostat in treating women who are undergoing surgery for newly diagnosed stage I, stage II, or stage III breast cancer
-
Stearns V (2005) NCT 00262834. Vorinostat in treating women who are undergoing surgery for newly diagnosed stage I, stage II, or stage III breast cancer. https://clinicaltrials.gov
-
(2005)
-
-
Stearns, V.1
-
117
-
-
84921814753
-
-
NCT 00616967. Carboplatin and paclitaxel albumin-stabilized nanoparticle formulation with or without vorinostat in treating women with breast cancer that can be removed by surgery
-
Stearns V (2008) NCT 00616967. Carboplatin and paclitaxel albumin-stabilized nanoparticle formulation with or without vorinostat in treating women with breast cancer that can be removed by surgery. https://clinicaltrials.gov
-
(2008)
-
-
Stearns, V.1
-
118
-
-
84921712943
-
-
NCT 00132002. Suberoylanilide hydroxamic acid in treating patients with progressive stage IV breast cancer
-
Luu T (2005) NCT 00132002. Suberoylanilide hydroxamic acid in treating patients with progressive stage IV breast cancer. https://clinicaltrials.gov
-
(2005)
-
-
Luu, T.1
-
119
-
-
84921767715
-
-
NCT 00365599. Phase II trial of SAHA & tamoxifen for patients with breast cancer
-
Minton S (2006) NCT 00365599. Phase II trial of SAHA & tamoxifen for patients with breast cancer. https://clinicaltrials.gov
-
(2006)
-
-
Minton, S.1
-
120
-
-
84921769899
-
-
NCT 01118975. Vorinostat and lapatinib in advanced solid tumors and advanced breast cancer to evaluate response and biomarkers
-
Chumsri S (2010) NCT 01118975. Vorinostat and lapatinib in advanced solid tumors and advanced breast cancer to evaluate response and biomarkers. https://clinicaltrials.gov
-
(2010)
-
-
Chumsri, S.1
|