Suberoylanilide Hydroxamic Acid, an Inhibitor of Histone Deacetylase, Enhances Radiosensitivity and Suppresses Lung Metastasis in Breast Cancer In Vitro and In Vivo

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Chiu, Hui Wen ^a   Yeh, Ya Ling ^a   Wang, Yi Ching ^a   Huang, Wei Jan ^b   Chen, Yi An ^a   Chiou, Yi Shiou ^a,c   Ho, Sheng Yow ^d   Lin, Pinpin ^e   Wang, Ying Jan ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL KAOHSIUNG UNIVERSITY OF APPLIED SCIENCES   (Taiwan)

^d CHI MEI MEDICAL CENTER   (Taiwan)

^e NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; GELATINASE B; HISTONE DEACETYLASE; VORINOSTAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGY; BREAST CANCER; CANCER INHIBITION; CONTROLLED STUDY; DISEASE MODEL; DNA DAMAGE; DNA REPAIR; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; LUNG METASTASIS; METASTASIS INHIBITION; MOUSE; NONHUMAN; RADIOSENSITIVITY;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COMBINED MODALITY THERAPY; DNA DAMAGE; DNA REPAIR; ENDOPLASMIC RETICULUM STRESS; FEMALE; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; LUNG NEOPLASMS; MICE; NEOPLASM INVASIVENESS; RADIATION TOLERANCE; SURVIVAL ANALYSIS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84885414197     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076340     Document Type: Article

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