Trichostatin A and 5 Aza-2′ deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR

Breast Cancer Research and Treatment

Volumn 111, Issue 1, 2008, Pages 15-25

  Pryzbylkowski, Peter ^a   Obajimi, Oluwakemi ^a   Keen, Judith Clancy ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

5 Aza 2 deoxycytidine; Actinomycin D; Breast cancer; Estrogen receptor alpha; HuR; MCF7; mRNA stability; Trichostatin A

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; DACTINOMYCIN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HISTONE; HUR PROTEIN; MESSENGER RNA; RNA BINDING PROTEIN; SMALL INTERFERING RNA; TRICHOSTATIN A;

3' UNTRANSLATED REGION; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL STRAIN MCF 7; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DEACETYLATION; DNA METHYLATION; DRUG MECHANISM; EPIGENETICS; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; RNA STABILITY; STEADY STATE;

3' UNTRANSLATED REGIONS; ANTIGENS, SURFACE; AZACITIDINE; BASE SEQUENCE; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE, TUMOR; ENZYME INHIBITORS; EPIGENESIS, GENETIC; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR MODULATORS; FEMALE; HUMANS; HYDROXAMIC ACIDS; IMMUNOPRECIPITATION; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA STABILITY; RNA, MESSENGER; RNA-BINDING PROTEINS; TRANSFECTION;

EID: 47549097004     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-007-9751-0     Document Type: Article

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