Epigenetic repression of PDZ-LIM domain-containing protein 2: Implications for the biology and treatment of breast cancer

Journal of Biological Chemistry

Volumn 285, Issue 16, 2010, Pages 11786-11792

  Qu, Zhaoxia ^a,b   Fu, Jing ^a,b   Yan, Pengrong ^a,b   Hu, Jing ^a   Cheng, Shi Yuan ^a   Xiao, Gutian ^a,b  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER; BREAST CANCER CELLS; DNA METHYLTRANSFERASES; ESTROGEN RECEPTOR; HUMAN BREAST CANCER CELLS; IN-VITRO; IN-VIVO; LIM DOMAIN; PROMOTER METHYLATION; THERAPEUTIC STRATEGY; TUMOR FORMATION; TUMOR SUPPRESSION;

ALKYLATION; BIOLOGY; GENES; METHYLATION; TRANSCRIPTION; TRANSCRIPTION FACTORS; TUMORS;

CELLS;

5 AZA 2' DEOXYCYTIDINE; CELL PROTEIN; ESTROGEN RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PDZ LIM DOMAIN CONTAINING PROTEIN 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CELL ANCHORAGE; CELL GROWTH; CELL STRAIN HEK293; CONTROLLED STUDY; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN METHYLATION; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; AZACITIDINE; BASE SEQUENCE; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA METHYLATION; DNA MODIFICATION METHYLASES; DNA PRIMERS; ENZYME INHIBITORS; EPIGENESIS, GENETIC; FEMALE; HUMANS; MICE; MICE, SCID; MICROFILAMENT PROTEINS; NF-KAPPA B; PROMOTER REGIONS, GENETIC; RECEPTORS, ESTROGEN; TUMOR STEM CELL ASSAY;

EID: 77951236061     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.086561     Document Type: Article

References (28)

1. Jemal, A., Siegel, R., Ward, E., Hao, Y., Xu, J., and Thun, M. J. (2009) CA Cancer J. Clin. 59, 225-249
2. Cao, Y., and Karin, M. (2003) J. Mammary Gland Biol. Neoplasia 8, 215-223
3. Wu, J. T., and Kral, J. G. (2005) J. Surg. Res. 123, 158-169
4. Biswas, D. K., and Iglehart, J. D. (2006) J. Cell. Physiol. 209, 645-652
5. Nakshatri, H., Bhat-Nakshatri, P., Martin, D. A., Goulet, R. J., Jr., and Sledge, G. W., Jr. (1997) Mol. Cell. Biol. 17, 3629-3639
6. Pratt, M. A., Tibbo, E., Robertson, S. J., Jansson, D., Hurst, K., Perez-Iratxeta, C., Lau, R., and Niu, M. Y. (2009) Oncogene 28, 2710-2722
7. Xiao, G. (2007) Cytokine Growth Factor Rev. 18, 233-243
8. Xiao, G., Rabson, A. B., Young, W., Qing, G., and Qu, Z. (2006) Cytokine Growth Factor Rev. 17, 281-293
9. Saccani, S., Marazzi, I., Beg, A. A., and Natoli, G. (2004) J. Exp. Med. 200, 107-113
10. Tanaka, T., Grusby, M. J., and Kaisho, T. (2007) Nat. Immunol. 8, 584-591
11. Yan, P., Fu, J., Qu, Z., Li, S., Tanaka, T., Grusby, M. J., and Xiao, G. (2009) Blood 113, 4370-4380
12. Qing, G., Yan, P., Qu, Z., Liu, H., and Xiao, G. (2007) Cell Res. 17, 520-530
13. Qing, G., Qu, Z., and Xiao, G. (2005) J. Biol. Chem. 280, 40578-40582
14. Qu, Z., Qing, G., Rabson, A., and Xiao, G. (2004) J. Biol. Chem. 279, 44563-44572
15. Qing, G., Qu, Z., and Xiao, G. (2005) J. Biol. Chem. 280, 18-27
16. Yan, P., Qu, Z., Ishikawa, C., Mori, N., and Xiao, G. (2009) Neoplasia 11, 1036-1041
17. Qing, G., Yan, P., and Xiao, G. (2006) Cell Res. 16, 895-901
18. Qu, Z., Yan, P., Fu, J., Jiang, J., Grusby, M. J., Smithgall, T. E., and Xiao, G. (2010) Cancer Res. 70, 1766-1772
19. Sun, S. C., and Xiao, G. (2003) Cancer Metastasis Rev. 22, 405-422
20. Cvijic, M. E., Xiao, G., and Sun, S. C. (2003) J. Immunol. Methods 278, 293-304
21. Qing, G., Qu, Z., and Xiao, G. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 5324-5329
22. Luczak, M., and Jagodziñski, P. P. (2006) Folia Histochem. Cytobiol. 44, 143-154
23. Garcia-Manero, G. (2008) Curr. Opin. Oncol. 20, 705-710
24. Samlowski, W. E., Leachman, S. A., Wade, M., Cassidy, P., Porter-Gill, P., Busby, L., Wheeler, R., Boucher, K., Fitzpatrick, F., Jones, D. A., and Karpf, A. R. (2005) J. Clin. Oncol. 23, 3897-3905
25. Lo, P. K., and Sukumar, S. (2008) Pharmacogenomics 9, 1879-1902
26. Torrado, M., Senatorov, V. V., Trivedi, R., Fariss, R. N., and Tomarev, S. I. (2004) Invest. Ophthalmol Vis. Sci. 45, 3955-3963
27. Loughran, G., Healy, N. C., Kiely, P. A., Huigsloot, M., Kedersha, N. L., and O'Connor, R. (2005) Mol. Biol. Cell 16, 1811-1822
28. Tanaka, T., Soriano, M. A., and Grusby, M. J. (2005) Immunity 22, 729-736